检索结果 - Hubank, Michael

Revealing Individual Signatures of Human T Cell CDR3 Sequence Repertoires with Kidera Factors 由 Epstein, Michael, Barenco, Martino, Klein, Nigel, Hubank, Michael, Callard, Robin E.

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Correction of scaling mismatches in oligonucleotide microarray data 由 Barenco, Martino, Stark, Jaroslav, Brewer, Daniel, Tomescu, Daniela, Callard, Robin, Hubank, Michael

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Ranked prediction of p53 targets using hidden variable dynamic modeling 由 Barenco, Martino, Tomescu, Daniela, Brewer, Daniel, Callard, Robin, Stark, Jaroslav, Hubank, Michael

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Dissection of a complex transcriptional response using genome-wide transcriptional modelling 由 Barenco, Martino, Brewer, Daniel, Papouli, Efterpi, Tomescu, Daniela, Callard, Robin, Stark, Jaroslav, Hubank, Michael

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Lineage-Independent Tumors in Bilateral Neuroblastoma 由 Coorens, Tim H.H., Farndon, Sarah J., Mitchell, Thomas J., Jain, Neha, Lee, Sangjin, Hubank, Michael, Sebire, Neil, Anderson, John, Behjati, Sam

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DIPG-25. GENETIC ALTERATIONS TARGETING THE MAPK PATHWAY CONFERS PRECLINICAL SENSITIVITY TO TRAMETINIB IN A CO-CLINICAL TRIAL IN DIPG 由 Izquierdo, Elisa, Carvalho, Diana, Boult, Jessica, Mackay, Alan, Temelso, Sara, Molinari, Valeria, Stubbs, Mark, Burke, Rosemary, Depani, Sarita, O’Hare, Patricia, Robinson, Simon, Hubank, Michael, Hargrave, Darren, Jones, Chris

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MODL-19. DIPG HARBOUR ALTERATIONS TARGETABLE BY MEK INHIBITORS, WITH ACQUIRED RESISTANCE MECHANISMS OVERCOME BY COMBINATORIAL UP- OR DOWN-STREAM INHIBITION 由 Izquierdo, Elisa, Carvalho, Diana, Mackay, Alan, Temelso, Sara, Boult, Jessica K R, Molinari, Valeria, Stubbs, Mark, Depani, Sarita, O’Hare, Patricia, Robinson, Simon P, Hubank, Michael, Hargrave, Darren, Jones, Chris

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Optimised ARID1A immunohistochemistry is an accurate predictor of ARID1A mutational status in gynaecological cancers 由 Khalique, Saira, Naidoo, Kalnisha, Attygalle, Ayoma D, Kriplani, Divya, Daley, Frances, Lowe, Anne, Campbell, James, Jones, Thomas, Hubank, Michael, Fenwick, Kerry, Matthews, Nicholas, Rust, Alistair G, Lord, Christopher J, Banerjee, Susana, Natrajan, Rachael

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DDRE-07. DIPG HARBOUR ALTERATIONS TARGETABLE BY MEK INHIBITORS, WITH ACQUIRED RESISTANCE MECHANISMS OVERCOME BY COMBINATORIAL INHIBITION 由 Izquierdo, Elisa, Carvalho, Diana, Mackay, Alan, Temelso, Sara, Boult, Jessica K R, Molinari, Valeria, Stubbs, Mark, Grabovska, Yura, Yu, Lu, Choudhary, Jyoti, Depani, Sarita, o’Hare, Patricia, Robinson, Simon P, Hubank, Michael, Hargrave, Darren, Jones, Chris

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Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson‐Gilford progeria syndrome fibroblasts, ex... 由 Bikkul, Mehmet U., Faragher, Richard G. A., Worthington, Gemma, Meinke, Peter, Kerr, Alastair R. W., Sammy, Aakila, Riyahi, Kumars, Horton, Daniel, Schirmer, Eric C., Hubank, Michael, Kill, Ian R., Anderson, Rhona M., Slijepcevic, Predrag, Makarov, Evgeny, Bridger, Joanna M.

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Identification of a novel genetic locus associated with immune-mediated thrombotic thrombocytopenic purpura 由 Stubbs, Matthew J., Coppo, Paul, Cheshire, Chris, Veyradier, Agnès, Dufek, Stephanie, Levine, Adam P., Thomas, Mari, Patel, Vaksha, Connolly, John O., Hubank, Michael, Benhamou, Ygal, Galicier, Lionel, Poullin, Pascale, Kleta, Robert, Gale, Daniel P., Stanescu, Horia, Scully, Marie A.

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Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer 由 Chopra, Neha, Tovey, Holly, Pearson, Alex, Cutts, Ros, Toms, Christy, Proszek, Paula, Hubank, Michael, Dowsett, Mitch, Dodson, Andrew, Daley, Frances, Kriplani, Divya, Gevensleben, Heidi, Davies, Helen Ruth, Degasperi, Andrea, Roylance, Rebecca, Chan, Stephen, Tutt, Andrew, Skene, Anthony, Evans, Abigail, Bliss, Judith M., Nik-Zainal, Serena, Turner, Nicholas C.

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Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients 由 Izquierdo, Elisa, Proszek, Paula, Pericoli, Giulia, Temelso, Sara, Clarke, Matthew, Carvalho, Diana M, Mackay, Alan, Marshall, Lynley V, Carceller, Fernando, Hargrave, Darren, Lannering, Birgitta, Pavelka, Zdenek, Bailey, Simon, Entz-Werle, Natacha, Grill, Jacques, Vassal, Gilles, Rodriguez, Daniel, Morgan, Paul S, Jaspan, Tim, Mastronuzzi, Angela, Vinci, Mara, Hubank, Michael, Jones, Chris

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EXTH-46. ARTIFICIAL INTELLIGENCE-BASED IDENTIFICATION OF COMBINED VANDETANIB AND EVEROLIMUS IN THE TREATMENT OF ACVR1-MUTANT DIFFUSE INTRINSIC PONTINE GLIOMA 由 Carvalho, Diana, Richardson, Peter, Olaciregui, Nagore Gene, Stankunaite, Reda, Lavarino, Cinzia Emilia, Molinari, Valeria, Corley, Elizabeth, Ruddle, Ruth, Donovan, Adam, Pal, Akos, Raynaud, Florence I, Overington, John P, Phelan, Anne, Sheppard, Dave, Mackinnon, Andrew, Hubank, Michael, Cruz, Ofelia, Madrid, Andres Morales La, Mueller, Sabine, Carcaboso, Angel Montero, Carceller, Fernando, Jones, Chris

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Quantitative Assessment and Prognostic Associations of the Immune Landscape in Ovarian Clear Cell Carcinoma 由 Khalique, Saira, Nash, Sarah, Mansfield, David, Wampfler, Julian, Attygale, Ayoma, Vroobel, Katherine, Kemp, Harriet, Buus, Richard, Cottom, Hannah, Roxanis, Ioannis, Jones, Thomas, von Loga, Katharina, Begum, Dipa, Guppy, Naomi, Ramagiri, Pradeep, Fenwick, Kerry, Matthews, Nik, Hubank, Michael J. F., Lord, Christopher J., Haider, Syed, Melcher, Alan, Banerjee, Susana, Natrajan, Rachael

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MODL-20. A BIOBANK OF ~100 PATIENT-DERIVED MODELS REPRESENTING BIOLOGICAL HETEROGENEITY AND DISTINCT THERAPEUTIC DEPENDENCIES IN PAEDIATRIC HIGH GRADE GLIOMA AND DIPG 由 Carvalho, Diana, Mackay, Alan, Temelso, Sara, Izquierdo, Elisa, Fernandez, Elisabet Potente, Rogers, Rebecca, Boult, Jessica, Salom, Janat Fazal, Simon, Natalie, Clarke, Matthew, Molinari, Valeria, Kessler, Ketty, Burford, Anna, Bjerke, Lynn, Fofana, Mariama, Hubank, Michael, Pears, Jane, Moore, Andrew, Carcaboso, Angel Montero, Marshall, Lynley, Carceller, Fernando, Robinson, Simon, Hargrave, Darren, Vinci, Maria, Jones, Chris

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Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours 由 Izquierdo, Elisa, Yuan, Lina, George, Sally, Hubank, Michael, Jones, Chris, Proszek, Paula, Shipley, Janet, Gatz, Susanne A., Stinson, Caedyn, Moore, Andrew S., Clifford, Steven C., Hicks, Debbie, Lindsey, Janet C., Hill, Rebecca M., Jacques, Thomas S., Chalker, Jane, Thway, Khin, O’Connor, Simon, Marshall, Lynley, Moreno, Lucas, Pearson, Andrew, Chesler, Louis, Walker, Brian A., De Castro, David Gonzalez

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Genomic profile of advanced breast cancer in circulating tumour DNA 由 Kingston, Belinda, Cutts, Rosalind J., Bye, Hannah, Beaney, Matthew, Walsh-Crestani, Giselle, Hrebien, Sarah, Swift, Claire, Kilburn, Lucy S., Kernaghan, Sarah, Moretti, Laura, Wilkinson, Katie, Wardley, Andrew M., Macpherson, Iain R., Baird, Richard D., Roylance, Rebecca, Reis-Filho, Jorge S., Hubank, Michael, Faull, Iris, Banks, Kimberly C., Lanman, Richard B., Garcia-Murillas, Isaac, Bliss, Judith M., Ring, Alistair, Turner, Nicholas C.

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Author Correction: Genomic profile of advanced breast cancer in circulating tumor DNA 由 Kingston, Belinda, Cutts, Rosalind J., Bye, Hannah, Beaney, Matthew, Walsh-Crestani, Giselle, Hrebien, Sarah, Swift, Claire, Kilburn, Lucy S., Kernaghan, Sarah, Moretti, Laura, Wilkinson, Katie, Wardley, Andrew M., Macpherson, Iain R., Baird, Richard D., Roylance, Rebecca, Reis-Filho, Jorge S., Hubank, Michael, Faull, Iris, Banks, Kimberly C., Lanman, Richard B., Garcia-Murillas, Isaac, Bliss, Judith M., Ring, Alistair, Turner, Nicholas C.

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Circulating tumour DNA analysis to direct therapy in advanced breast cancer (plasmaMATCH): a multicentre, multicohort, phase 2a, platform trial 由 Turner, Nicholas C, Kingston, Belinda, Kilburn, Lucy S, Kernaghan, Sarah, Wardley, Andrew M, Macpherson, Iain R, Baird, Richard D, Roylance, Rebecca, Stephens, Peter, Oikonomidou, Olga, Braybrooke, Jeremy P, Tuthill, Mark, Abraham, Jacinta, Winter, Matthew C, Bye, Hannah, Hubank, Michael, Gevensleben, Heidrun, Cutts, Ros, Snowdon, Claire, Rea, Daniel, Cameron, David, Shaaban, Abeer, Randle, Katrina, Martin, Sue, Wilkinson, Katie, Moretti, Laura, Bliss, Judith M, Ring, Alistair

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