نتائج البحث - Hubank, Michael

Revealing Individual Signatures of Human T Cell CDR3 Sequence Repertoires with Kidera Factors حسب Epstein, Michael, Barenco, Martino, Klein, Nigel, Hubank, Michael, Callard, Robin E.

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Correction of scaling mismatches in oligonucleotide microarray data حسب Barenco, Martino, Stark, Jaroslav, Brewer, Daniel, Tomescu, Daniela, Callard, Robin, Hubank, Michael

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Ranked prediction of p53 targets using hidden variable dynamic modeling حسب Barenco, Martino, Tomescu, Daniela, Brewer, Daniel, Callard, Robin, Stark, Jaroslav, Hubank, Michael

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Dissection of a complex transcriptional response using genome-wide transcriptional modelling حسب Barenco, Martino, Brewer, Daniel, Papouli, Efterpi, Tomescu, Daniela, Callard, Robin, Stark, Jaroslav, Hubank, Michael

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Lineage-Independent Tumors in Bilateral Neuroblastoma حسب Coorens, Tim H.H., Farndon, Sarah J., Mitchell, Thomas J., Jain, Neha, Lee, Sangjin, Hubank, Michael, Sebire, Neil, Anderson, John, Behjati, Sam

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DIPG-25. GENETIC ALTERATIONS TARGETING THE MAPK PATHWAY CONFERS PRECLINICAL SENSITIVITY TO TRAMETINIB IN A CO-CLINICAL TRIAL IN DIPG حسب Izquierdo, Elisa, Carvalho, Diana, Boult, Jessica, Mackay, Alan, Temelso, Sara, Molinari, Valeria, Stubbs, Mark, Burke, Rosemary, Depani, Sarita, O’Hare, Patricia, Robinson, Simon, Hubank, Michael, Hargrave, Darren, Jones, Chris

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MODL-19. DIPG HARBOUR ALTERATIONS TARGETABLE BY MEK INHIBITORS, WITH ACQUIRED RESISTANCE MECHANISMS OVERCOME BY COMBINATORIAL UP- OR DOWN-STREAM INHIBITION حسب Izquierdo, Elisa, Carvalho, Diana, Mackay, Alan, Temelso, Sara, Boult, Jessica K R, Molinari, Valeria, Stubbs, Mark, Depani, Sarita, O’Hare, Patricia, Robinson, Simon P, Hubank, Michael, Hargrave, Darren, Jones, Chris

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Optimised ARID1A immunohistochemistry is an accurate predictor of ARID1A mutational status in gynaecological cancers حسب Khalique, Saira, Naidoo, Kalnisha, Attygalle, Ayoma D, Kriplani, Divya, Daley, Frances, Lowe, Anne, Campbell, James, Jones, Thomas, Hubank, Michael, Fenwick, Kerry, Matthews, Nicholas, Rust, Alistair G, Lord, Christopher J, Banerjee, Susana, Natrajan, Rachael

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DDRE-07. DIPG HARBOUR ALTERATIONS TARGETABLE BY MEK INHIBITORS, WITH ACQUIRED RESISTANCE MECHANISMS OVERCOME BY COMBINATORIAL INHIBITION حسب Izquierdo, Elisa, Carvalho, Diana, Mackay, Alan, Temelso, Sara, Boult, Jessica K R, Molinari, Valeria, Stubbs, Mark, Grabovska, Yura, Yu, Lu, Choudhary, Jyoti, Depani, Sarita, o’Hare, Patricia, Robinson, Simon P, Hubank, Michael, Hargrave, Darren, Jones, Chris

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Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson‐Gilford progeria syndrome fibroblasts, ex... حسب Bikkul, Mehmet U., Faragher, Richard G. A., Worthington, Gemma, Meinke, Peter, Kerr, Alastair R. W., Sammy, Aakila, Riyahi, Kumars, Horton, Daniel, Schirmer, Eric C., Hubank, Michael, Kill, Ian R., Anderson, Rhona M., Slijepcevic, Predrag, Makarov, Evgeny, Bridger, Joanna M.

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Identification of a novel genetic locus associated with immune-mediated thrombotic thrombocytopenic purpura حسب Stubbs, Matthew J., Coppo, Paul, Cheshire, Chris, Veyradier, Agnès, Dufek, Stephanie, Levine, Adam P., Thomas, Mari, Patel, Vaksha, Connolly, John O., Hubank, Michael, Benhamou, Ygal, Galicier, Lionel, Poullin, Pascale, Kleta, Robert, Gale, Daniel P., Stanescu, Horia, Scully, Marie A.

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Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer حسب Chopra, Neha, Tovey, Holly, Pearson, Alex, Cutts, Ros, Toms, Christy, Proszek, Paula, Hubank, Michael, Dowsett, Mitch, Dodson, Andrew, Daley, Frances, Kriplani, Divya, Gevensleben, Heidi, Davies, Helen Ruth, Degasperi, Andrea, Roylance, Rebecca, Chan, Stephen, Tutt, Andrew, Skene, Anthony, Evans, Abigail, Bliss, Judith M., Nik-Zainal, Serena, Turner, Nicholas C.

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Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients حسب Izquierdo, Elisa, Proszek, Paula, Pericoli, Giulia, Temelso, Sara, Clarke, Matthew, Carvalho, Diana M, Mackay, Alan, Marshall, Lynley V, Carceller, Fernando, Hargrave, Darren, Lannering, Birgitta, Pavelka, Zdenek, Bailey, Simon, Entz-Werle, Natacha, Grill, Jacques, Vassal, Gilles, Rodriguez, Daniel, Morgan, Paul S, Jaspan, Tim, Mastronuzzi, Angela, Vinci, Mara, Hubank, Michael, Jones, Chris

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EXTH-46. ARTIFICIAL INTELLIGENCE-BASED IDENTIFICATION OF COMBINED VANDETANIB AND EVEROLIMUS IN THE TREATMENT OF ACVR1-MUTANT DIFFUSE INTRINSIC PONTINE GLIOMA حسب Carvalho, Diana, Richardson, Peter, Olaciregui, Nagore Gene, Stankunaite, Reda, Lavarino, Cinzia Emilia, Molinari, Valeria, Corley, Elizabeth, Ruddle, Ruth, Donovan, Adam, Pal, Akos, Raynaud, Florence I, Overington, John P, Phelan, Anne, Sheppard, Dave, Mackinnon, Andrew, Hubank, Michael, Cruz, Ofelia, Madrid, Andres Morales La, Mueller, Sabine, Carcaboso, Angel Montero, Carceller, Fernando, Jones, Chris

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Quantitative Assessment and Prognostic Associations of the Immune Landscape in Ovarian Clear Cell Carcinoma حسب Khalique, Saira, Nash, Sarah, Mansfield, David, Wampfler, Julian, Attygale, Ayoma, Vroobel, Katherine, Kemp, Harriet, Buus, Richard, Cottom, Hannah, Roxanis, Ioannis, Jones, Thomas, von Loga, Katharina, Begum, Dipa, Guppy, Naomi, Ramagiri, Pradeep, Fenwick, Kerry, Matthews, Nik, Hubank, Michael J. F., Lord, Christopher J., Haider, Syed, Melcher, Alan, Banerjee, Susana, Natrajan, Rachael

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MODL-20. A BIOBANK OF ~100 PATIENT-DERIVED MODELS REPRESENTING BIOLOGICAL HETEROGENEITY AND DISTINCT THERAPEUTIC DEPENDENCIES IN PAEDIATRIC HIGH GRADE GLIOMA AND DIPG حسب Carvalho, Diana, Mackay, Alan, Temelso, Sara, Izquierdo, Elisa, Fernandez, Elisabet Potente, Rogers, Rebecca, Boult, Jessica, Salom, Janat Fazal, Simon, Natalie, Clarke, Matthew, Molinari, Valeria, Kessler, Ketty, Burford, Anna, Bjerke, Lynn, Fofana, Mariama, Hubank, Michael, Pears, Jane, Moore, Andrew, Carcaboso, Angel Montero, Marshall, Lynley, Carceller, Fernando, Robinson, Simon, Hargrave, Darren, Vinci, Maria, Jones, Chris

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Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours حسب Izquierdo, Elisa, Yuan, Lina, George, Sally, Hubank, Michael, Jones, Chris, Proszek, Paula, Shipley, Janet, Gatz, Susanne A., Stinson, Caedyn, Moore, Andrew S., Clifford, Steven C., Hicks, Debbie, Lindsey, Janet C., Hill, Rebecca M., Jacques, Thomas S., Chalker, Jane, Thway, Khin, O’Connor, Simon, Marshall, Lynley, Moreno, Lucas, Pearson, Andrew, Chesler, Louis, Walker, Brian A., De Castro, David Gonzalez

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Genomic profile of advanced breast cancer in circulating tumour DNA حسب Kingston, Belinda, Cutts, Rosalind J., Bye, Hannah, Beaney, Matthew, Walsh-Crestani, Giselle, Hrebien, Sarah, Swift, Claire, Kilburn, Lucy S., Kernaghan, Sarah, Moretti, Laura, Wilkinson, Katie, Wardley, Andrew M., Macpherson, Iain R., Baird, Richard D., Roylance, Rebecca, Reis-Filho, Jorge S., Hubank, Michael, Faull, Iris, Banks, Kimberly C., Lanman, Richard B., Garcia-Murillas, Isaac, Bliss, Judith M., Ring, Alistair, Turner, Nicholas C.

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Author Correction: Genomic profile of advanced breast cancer in circulating tumor DNA حسب Kingston, Belinda, Cutts, Rosalind J., Bye, Hannah, Beaney, Matthew, Walsh-Crestani, Giselle, Hrebien, Sarah, Swift, Claire, Kilburn, Lucy S., Kernaghan, Sarah, Moretti, Laura, Wilkinson, Katie, Wardley, Andrew M., Macpherson, Iain R., Baird, Richard D., Roylance, Rebecca, Reis-Filho, Jorge S., Hubank, Michael, Faull, Iris, Banks, Kimberly C., Lanman, Richard B., Garcia-Murillas, Isaac, Bliss, Judith M., Ring, Alistair, Turner, Nicholas C.

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Circulating tumour DNA analysis to direct therapy in advanced breast cancer (plasmaMATCH): a multicentre, multicohort, phase 2a, platform trial حسب Turner, Nicholas C, Kingston, Belinda, Kilburn, Lucy S, Kernaghan, Sarah, Wardley, Andrew M, Macpherson, Iain R, Baird, Richard D, Roylance, Rebecca, Stephens, Peter, Oikonomidou, Olga, Braybrooke, Jeremy P, Tuthill, Mark, Abraham, Jacinta, Winter, Matthew C, Bye, Hannah, Hubank, Michael, Gevensleben, Heidrun, Cutts, Ros, Snowdon, Claire, Rea, Daniel, Cameron, David, Shaaban, Abeer, Randle, Katrina, Martin, Sue, Wilkinson, Katie, Moretti, Laura, Bliss, Judith M, Ring, Alistair

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