Søgeresultater - Huang, Shar‐yin N

The Role of Nucleotide Cofactor Binding in Cooperativity and Specificity of MutS Recognition af Huang, Shar-yin N., Crothers, Donald M.

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Tyrosyl-DNA Phosdiesterase 1 (Tdp1) Inhibitors af Huang, Shar-yin N., Pommier, Yves, Marchand, Christophe

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Biochemical Characterization of Human Tyrosyl-DNA Phosphodiesterase 2 (TDP2/TTRAP): A Mg(2+)/Mn(2+)-DEPENDENT PHOSPHODIESTERASE SPECIFIC FOR THE REPAIR OF TOPOISOMERASE CLEAVAGE CO... af Gao, Rui, Huang, Shar-yin N., Marchand, Christophe, Pommier, Yves

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Roles of eukaryotic topoisomerases in transcription, replication and genomic stability af Pommier, Yves, Sun, Yilun, Huang, Shar-yin N., Nitiss, John L.

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Topoisomerase I‐mediated cleavage at unrepaired ribonucleotides generates DNA double‐strand breaks af Huang, Shar‐yin N, Williams, Jessica S, Arana, Mercedes E, Kunkel, Thomas A, Pommier, Yves

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The indenoisoquinoline LMP517: a novel antitumor agent targeting both TOP1 and TOP2 af Marzi, Laetitia, Sun, Yilun, Huang, Shar-yin N., James, Amy, Difilippantonio, Simone, Pommier, Yves

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Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Repairs DNA Damage Induced by Topoisomerases I and II and Base Alkylation in Vertebrate Cells af Murai, Junko, Huang, Shar-yin N., Das, Benu Brata, Dexheimer, Thomas S., Takeda, Shunichi, Pommier, Yves

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Tyrosyl-DNA-phosphodiesterases (TDP1 and TDP2) af Pommier, Yves, Huang, Shar-yin N., Gao, Rui, Das, Benu Brata, Murai, Junko, Marchand, Christophe

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Mapping Topoisomerase Sites in Mitochondrial DNA with a Poisonous Mitochondrial Topoisomerase I (Top1mt) af Dalla Rosa, Ilaria, Huang, Shar-yin N., Agama, Keli, Khiati, Salim, Zhang, Hongliang, Pommier, Yves

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Parallel analysis of ribonucleotide-dependent deletions produced by yeast Top1 in vitro and in vivo af Cho, Jang-Eun, Huang, Shar-yin N., Burgers, Peter M., Shuman, Stewart, Pommier, Yves, Jinks-Robertson, Sue

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TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs af Huang, Shar-yin N., Murai, Junko, Dalla Rosa, Ilaria, Dexheimer, Thomas S., Naumova, Alena, Gmeiner, William H., Pommier, Yves

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TDP1 suppresses mis-joining of radiomimetic DNA double-strand breaks and cooperates with Artemis to promote optimal nonhomologous end joining af Kawale, Ajinkya S, Akopiants, Konstantin, Valerie, Kristoffer, Ruis, Brian, Hendrickson, Eric A, Huang, Shar-yin N, Pommier, Yves, Povirk, Lawrence F

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Differential trapping of PARP1 and PARP2 by clinical PARP inhibitors af Murai, Junko, Huang, Shar-yin N., Das, Benu Brata, Renaud, Amelie, Zhang, Yiping, Doroshow, James H., Ji, Jiuping, Takeda, Shunichi, Pommier, Yves

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Stereospecific PARP trapping by BMN 673 and comparison with olaparib and rucaparib af Murai, Junko, Huang, Shar-yin N., Renaud, Amèlie, Zhang, Yiping, Ji, Jiuping, Takeda, Shunichi, Morris, Joel, Teicher, Beverly, Doroshow, James H., Pommier, Yves

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Proteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2·DNA and Top2·RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2) af Gao, Rui, Schellenberg, Matthew J., Huang, Shar-yin N., Abdelmalak, Monica, Marchand, Christophe, Nitiss, Karin C., Nitiss, John L., Williams, R. Scott, Pommier, Yves

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SLFN11 inactivation induces proteotoxic stress and sensitizes cancer cells to ubiquitin activating enzyme inhibitor TAK-243 af Murai, Yasuhisa, Jo, Ukhyun, Murai, Junko, Jenkins, Lisa, Huang, Shar-Yin N., Chakka, Sirisha, Chen, Lu, Cheng, Ken, Fukuda, Shinsaku, Takebe, Naoko, Pommier, Yves

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Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration af Khiati, Salim, Baechler, Simone A., Factor, Valentina M., Zhang, Hongliang, Huang, Shar-yin N., Dalla Rosa, Ilaria, Sourbier, Carole, Neckers, Leonard, Thorgeirsson, Snorri S., Pommier, Yves

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Exonuclease VII repairs quinolone-induced damage by resolving DNA gyrase cleavage complexes af Huang, Shar-yin N., Michaels, Stephanie A., Mitchell, Brianna B., Majdalani, Nadim, Vanden Broeck, Arnaud, Canela, Andres, Tse-Dinh, Yuk-Ching, Lamour, Valerie, Pommier, Yves

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PARylation prevents the proteasomal degradation of topoisomerase I DNA-protein crosslinks and induces their deubiquitylation af Sun, Yilun, Chen, Jiji, Huang, Shar-yin N., Su, Yijun P., Wang, Wenjie, Agama, Keli, Saha, Sourav, Jenkins, Lisa M., Pascal, John M., Pommier, Yves

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Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity af Canela, Andres, Maman, Yaakov, Huang, Shar-yin N., Wutz, Gordana, Tang, Wen, Zagnoli-Vieira, Guido, Callen, Elsa, Wong, Nancy, Day, Amanda, Peters, Jan-Michael, Caldecott, Keith W., Pommier, Yves, Nussenzweig, André

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