Torthaí cuardaigh - Homme W. Hellinga

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  1. 1
    Rational protein design: Combining theory and experiment

    Rational protein design: Combining theory and experiment de réir Homme W. Hellinga

    Foilsithe / Cruthaithe 1997
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  2. 2
    An empirical model for electrostatic interactions in proteins incorporating multiple geometry‐dependent dielectric constants

    An empirical model for electrostatic interactions in proteins incorporating multiple geometry‐dependent dielectric constants de réir Michael S. Wisz, Homme W. Hellinga

    Foilsithe / Cruthaithe 2003
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  3. 3
    Construction of new ligand binding sites in proteins of known structure

    Construction of new ligand binding sites in proteins of known structure de réir Homme W. Hellinga, Frederic M. Richards

    Foilsithe / Cruthaithe 1991
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  4. 4
    Quantitation of protein–protein interactions by thermal stability shift analysis

    Quantitation of protein–protein interactions by thermal stability shift analysis de réir Curtis J. Layton, Homme W. Hellinga

    Foilsithe / Cruthaithe 2011
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  5. 5
    Optimal sequence selection in proteins of known structure by simulated evolution.

    Optimal sequence selection in proteins of known structure by simulated evolution. de réir Homme W. Hellinga, F.M. Richards

    Foilsithe / Cruthaithe 1994
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  6. 6
    Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I

    Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I de réir Yuqian Shi, Homme W. Hellinga, L.S. Beese

    Foilsithe / Cruthaithe 2017
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  7. 7
    Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis

    Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis de réir Wei-Na Wang, Homme W. Hellinga, L.S. Beese

    Foilsithe / Cruthaithe 2011
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  8. 8
    Multifactorial Determinants of Protein Expression in Prokaryotic Open Reading Frames

    Multifactorial Determinants of Protein Expression in Prokaryotic Open Reading Frames de réir Malin Allert, J. Colin Cox, Homme W. Hellinga

    Foilsithe / Cruthaithe 2010
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  9. 9
    Construction of new ligand binding sites in proteins of known structure

    Construction of new ligand binding sites in proteins of known structure de réir Homme W. Hellinga, John P. Caradonna, F.M. Richards

    Foilsithe / Cruthaithe 1991
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  10. 10
    Computational Design of a Biologically Active Enzyme

    Computational Design of a Biologically Active Enzyme de réir Mary A. Dwyer, Loren L. Looger, Homme W. Hellinga

    Foilsithe / Cruthaithe 2004
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  11. 11
    Structural Factors That Determine Selectivity of a High Fidelity DNA Polymerase for Deoxy-, Dideoxy-, and Ribonucleotides

    Structural Factors That Determine Selectivity of a High Fidelity DNA Polymerase for Deoxy-, Dideoxy-, and Ribonucleotides de réir Wei-Na Wang, Eugene Wu, Homme W. Hellinga, L.S. Beese

    Foilsithe / Cruthaithe 2012
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  12. 12
    The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics

    The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics de réir Stephen B. Long, Paula J. Hancock, Astrid M. Kral, Homme W. Hellinga, L.S. Beese

    Foilsithe / Cruthaithe 2001
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  13. 13
    The rational design of allosteric interactions in a monomeric protein and its applications to the construction of biosensors

    The rational design of allosteric interactions in a monomeric protein and its applications to the construction of biosensors de réir Jonathan S. Marvin, Elizabeth Corcoran, N. A. Hattangadi, J. V. Zhang, S. A. Gere, Homme W. Hellinga

    Foilsithe / Cruthaithe 1997
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  14. 14
    Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family

    Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family de réir Jillian Orans, Elizabeth McSweeney, Ravi Iyer, Michael A. Hast, Homme W. Hellinga, Paul Modrich, L.S. Beese

    Foilsithe / Cruthaithe 2011
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  15. 15
    Visualization of Synaptic Inhibition with an Optogenetic Sensor Developed by Cell-Free Protein Engineering Automation

    Visualization of Synaptic Inhibition with an Optogenetic Sensor Developed by Cell-Free Protein Engineering Automation de réir Joshua S. Grimley, Li Li, Wei-Na Wang, Wen Lei, L.S. Beese, Homme W. Hellinga, George J Augustine

    Foilsithe / Cruthaithe 2013
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  16. 16
    Structural Reorganization and Preorganization in Enzyme Active Sites: Comparisons of Experimental and Theoretically Ideal Active Site Geometries in the Multistep Serine Esterase Reaction Cycle

    Structural Reorganization and Preorganization in Enzyme Active Sites: Comparisons of Experimental and Theoretically Ideal Active Site Geometries in the Multistep Serine Esterase Re... de réir Adam J. T. Smith, Roger Müller, Miguel D. Toscano, Peter Kast, Homme W. Hellinga, Donald Hilvert, K. N. Houk

    Foilsithe / Cruthaithe 2008
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  17. 17
    Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens

    Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens de réir Michael A. Hast, Connie B. Nichols, Stephanie Armstrong, Shannon M. Kelly, Homme W. Hellinga, J. Andrew Alspaugh, L.S. Beese

    Foilsithe / Cruthaithe 2011
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