खोज परिणाम - Holmes, Michael C.

Targeted Gene Addition of Microdystrophin in Mice Skeletal Muscle via Human Myoblast Transplantation द्वारा Benabdallah, Basma F, Duval, Arnaud, Rousseau, Joel, Chapdelaine, Pierre, Holmes, Michael C, Haddad, Eli, Tremblay, Jacques P, Beauséjour, Christian M

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Use of zinc-finger nucleases to knock out the WAS gene in K562 cells: a human cellular model for Wiskott-Aldrich syndrome द्वारा Toscano, Miguel G., Anderson, Per, Muñoz, Pilar, Lucena, Gema, Cobo, Marién, Benabdellah, Karim, Gregory, Philip D., Holmes, Michael C., Martin, Francisco

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Zinc-finger Nuclease Editing of Human cxcr4 Promotes HIV-1 CD4(+) T Cell Resistance and Enrichment द्वारा Yuan, Jinyun, Wang, Jianbin, Crain, Karen, Fearns, Colleen, Kim, Kenneth A, Hua, Kevin L, Gregory, Philip D, Holmes, Michael C, Torbett, Bruce E

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Disruption of the BCL11A Erythroid Enhancer Reactivates Fetal Hemoglobin in Erythroid Cells of Patients with β-Thalassemia Major द्वारा Psatha, Nikoletta, Reik, Andreas, Phelps, Susan, Zhou, Yuanyue, Dalas, Demetri, Yannaki, Evangelia, Levasseur, Dana N., Urnov, Fyodor D., Holmes, Michael C., Papayannopoulou, Thalia

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Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases द्वारा Moehle, Erica A., Rock, Jeremy M., Lee, Ya-Li, Jouvenot, Yann, DeKelver, Russell C., Gregory, Philip D., Urnov, Fyodor D., Holmes, Michael C.

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ZFN-mediated in vivo gene editing in hepatocytes leads to supraphysiologic α-Gal A activity and effective substrate reduction in Fabry mice द्वारा Pagant, Silvere, Huston, Marshall W., Moreira, Luciana, Gan, Lin, St Martin, Susan, Sproul, Scott, Holmes, Michael C., Meyer, Kathleen, Wechsler, Thomas, Desnick, Robert J., Yasuda, Makiko

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Zinc finger nuclease-mediated CCR5 knockout hematopoietic stem cell transplantation controls HIV-1 in vivo द्वारा Holt, Nathalia, Wang, Jianbin, Kim, Kenneth, Friedman, Geoffrey, Wang, Xingchao, Taupin, Vanessa, Crooks, Gay M., Kohn, Donald B., Gregory, Philip D., Holmes, Michael C., Cannon, Paula M.

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Derivation and Characterization of a Simian Immunodeficiency Virus SIVmac239 Variant with Tropism for CXCR4 द्वारा Del Prete, Gregory Q., Haggarty, Beth, Leslie, George J., Jordan, Andrea P. O., Romano, Josephine, Wang, Nathaniel, Wang, Jianbin, Holmes, Michael C., Montefiori, David C., Hoxie, James A.

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Genome editing for scalable production of alloantigen‐free lentiviral vectors for in vivo gene therapy द्वारा Milani, Michela, Annoni, Andrea, Bartolaccini, Sara, Biffi, Mauro, Russo, Fabio, Di Tomaso, Tiziano, Raimondi, Andrea, Lengler, Johannes, Holmes, Michael C, Scheiflinger, Friedrich, Lombardo, Angelo, Cantore, Alessio, Naldini, Luigi

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Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme द्वारा Wang, Jianbin, Friedman, Geoffrey, Doyon, Yannick, Wang, Nathaniel S., Li, Carrie Jiaxin, Miller, Jeffrey C., Hua, Kevin L., Yan, Jenny Jiacheng, Babiarz, Joshua E., Gregory, Philip D., Holmes, Michael C.

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Simultaneous zinc-finger nuclease editing of the HIV coreceptors ccr5 and cxcr4 protects CD4(+) T cells from HIV-1 infection द्वारा Didigu, Chuka A., Wilen, Craig B., Wang, Jianbin, Duong, Jennifer, Secreto, Anthony J., Danet-Desnoyers, Gwenn A., Riley, James L., Gregory, Phillip D., June, Carl H., Holmes, Michael C., Doms, Robert W.

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DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation द्वारा Simsek, Deniz, Brunet, Erika, Wong, Sunnie Yan-Wai, Katyal, Sachin, Gao, Yankun, McKinnon, Peter J., Lou, Jacqueline, Zhang, Lei, Li, James, Rebar, Edward J., Gregory, Philip D., Holmes, Michael C., Jasin, Maria

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Absence of WASp Enhances Hematopoietic and Megakaryocytic Differentiation in a Human Embryonic Stem Cell Model द्वारा Toscano, Miguel G, Muñoz, Pilar, Sánchez-Gilabert, Almudena, Cobo, Marién, Benabdellah, Karim, Anderson, Per, Ramos-Mejía, Verónica, Real, Pedro J, Neth, Olaf, Molinos-Quintana, Agueda, Gregory, Philip D, Holmes, Michael C, Martin, Francisco

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Homology-driven genome editing in hematopoietic stem and progenitor cells using zinc finger nuclease mRNA and AAV6 donors द्वारा Wang, Jianbin, Exline, Colin M., DeClercq, Joshua J., Llewellyn, G. Nicholas, Hayward, Samuel B., Li, Patrick Wai-Lun, Shivak, David A., Surosky, Richard T., Gregory, Philip D., Holmes, Michael C., Cannon, Paula M

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Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy द्वारा Peterson, Christopher W., Wang, Jianbin, Deleage, Claire, Reddy, Sowmya, Kaur, Jasbir, Polacino, Patricia, Reik, Andreas, Huang, Meei-Li, Jerome, Keith R., Hu, Shiu-Lok, Holmes, Michael C., Estes, Jacob D., Kiem, Hans-Peter

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Cancer translocations in human cells induced by zinc finger and TALE nucleases द्वारा Piganeau, Marion, Ghezraoui, Hind, De Cian, Anne, Guittat, Lionel, Tomishima, Mark, Perrouault, Loic, René, Oliver, Katibah, George E., Zhang, Lei, Holmes, Michael C., Doyon, Yannick, Concordet, Jean-Paul, Giovannangeli, Carine, Jasin, Maria, Brunet, Erika

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Robust ZFN-mediated genome editing in adult hemophilic mice द्वारा Anguela, Xavier M., Sharma, Rajiv, Doyon, Yannick, Miller, Jeffrey C., Li, Hojun, Haurigot, Virginia, Rohde, Michelle E., Wong, Sunnie Y., Davidson, Robert J., Zhou, Shangzhen, Gregory, Philip D., Holmes, Michael C., High, Katherine A.

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Efficient genome editing in hematopoietic stem cells with helper-dependent Ad5/35 vectors expressing site-specific endonucleases under microRNA regulation द्वारा Saydaminova, Kamola, Ye, Xun, Wang, Hongjie, Richter, Maximilian, Ho, Martin, Chen, HongZhuan, Xu, Ning, Kim, Jin-Soo, Papapetrou, Eirini, Holmes, Michael C, Gregory, Philip D, Palmer, Donna, Ng, Philip, Ehrhardt, Anja, Lieber, André

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Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases द्वारा Santiago, Yolanda, Chan, Edmond, Liu, Pei-Qi, Orlando, Salvatore, Zhang, Lin, Urnov, Fyodor D., Holmes, Michael C., Guschin, Dmitry, Waite, Adam, Miller, Jeffrey C., Rebar, Edward J., Gregory, Philip D., Klug, Aaron, Collingwood, Trevor N.

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Therapeutic gene editing in CD34(+) hematopoietic progenitors from Fanconi anemia patients द्वारा Diez, Begoña, Genovese, Pietro, Roman‐Rodriguez, Francisco J, Alvarez, Lara, Schiroli, Giulia, Ugalde, Laura, Rodriguez‐Perales, Sandra, Sevilla, Julian, Diaz de Heredia, Cristina, Holmes, Michael C, Lombardo, Angelo, Naldini, Luigi, Bueren, Juan Antonio, Rio, Paula

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