检索结果 - Holger Fröhlich

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  1. 1
    Prognostic gene signatures for patient stratification in breast cancer - accuracy, stability and interpretability of gene selection approaches using prior knowledge on protein-protein interactions

    Prognostic gene signatures for patient stratification in breast cancer - accuracy, stability and interpretability of gene selection approaches using prior knowledge on protein-prot... 由 Yupeng Cun, Holger Fröhlich

    出版 2012
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  2. 2
    Network and Data Integration for Biomarker Signature Discovery via Network Smoothed T-Statistics

    Network and Data Integration for Biomarker Signature Discovery via Network Smoothed T-Statistics 由 Yupeng Cun, Holger Fröhlich

    出版 2013
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  3. 3
    MCMC Techniques for Parameter Estimation of ODE Based Models in Systems Biology

    MCMC Techniques for Parameter Estimation of ODE Based Models in Systems Biology 由 Gloria Isabel Valderrama Bahamóndez, Holger Fröhlich

    出版 2019
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  4. 4
    PathME: pathway based multi-modal sparse autoencoders for clustering of patient-level multi-omics data

    PathME: pathway based multi-modal sparse autoencoders for clustering of patient-level multi-omics data 由 Amina Lemsara, Salima Ouadfel, Holger Fröhlich

    出版 2020
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  5. 5
    GOSim – an R-package for computation of information theoretic GO similarities between terms and gene products

    GOSim – an R-package for computation of information theoretic GO similarities between terms and gene products 由 Holger Fröhlich, N. Speer, Annemarie Poustka, Tim Beißbarth

    出版 2007
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  6. 6
    Integrating digital gait data with metabolomics and clinical data to predict outcomes in Parkinson’s disease

    Integrating digital gait data with metabolomics and clinical data to predict outcomes in Parkinson’s disease 由 Cyril Brzenczek, Quentin Klopfenstein, Tom Hähnel, Holger Fröhlich, Enrico Glaab

    出版 2024
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  7. 7
    Premenopausal breast cancer: potential clinical utility of a multi-omics based machine learning approach for patient stratification

    Premenopausal breast cancer: potential clinical utility of a multi-omics based machine learning approach for patient stratification 由 Holger Fröhlich, Sabyasachi Patjoshi, Kristina Yeghiazaryan, Christina Kehrer, Walther Kuhn, Olga Golubnitschaja

    出版 2018
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  8. 8
    miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit

    miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit 由 Yong Chen, Franziska Siegel, Stefanie Kipschull, Bodo Haas, Holger Fröhlich, Gunter Meister, Alexander Pfeifer

    出版 2013
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  9. 9
    Evaluating the Alzheimer's disease data landscape

    Evaluating the Alzheimer's disease data landscape 由 Colin Birkenbihl, Yasamin Salimi, Daniel Domingo‐Fernándéz, Simon Lovestone, Holger Fröhlich, Martin Hofmann‐Apitius

    出版 2020
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  10. 10
    Using Multi-Scale Genetic, Neuroimaging and Clinical Data for Predicting Alzheimer’s Disease and Reconstruction of Relevant Biological Mechanisms

    Using Multi-Scale Genetic, Neuroimaging and Clinical Data for Predicting Alzheimer’s Disease and Reconstruction of Relevant Biological Mechanisms 由 Shashank Khanna, Daniel Domingo‐Fernándéz, Anandhi Iyappan, Mohammad Asif Emon, Martin Hofmann‐Apitius, Holger Fröhlich

    出版 2018
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  11. 11
    The Impact of Pathway Database Choice on Statistical Enrichment Analysis and Predictive Modeling

    The Impact of Pathway Database Choice on Statistical Enrichment Analysis and Predictive Modeling 由 Sarah Mubeen, Charles Tapley Hoyt, André Gemünd, Martin Hofmann‐Apitius, Holger Fröhlich, Daniel Domingo‐Fernándéz

    出版 2019
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  12. 12
    Epigenome-Wide Analysis of DNA Methylation in Parkinson’s Disease Cortex

    Epigenome-Wide Analysis of DNA Methylation in Parkinson’s Disease Cortex 由 Oliver Kaut, Ina Schmitt, Fabian Stahl, Holger Fröhlich, Per Hoffmann, Frank J. Gonzalez, Ullrich Wüllner

    出版 2022
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  13. 13
    Integration of pathway knowledge into a reweighted recursive feature elimination approach for risk stratification of cancer patients

    Integration of pathway knowledge into a reweighted recursive feature elimination approach for risk stratification of cancer patients 由 Marc Johannes, Jan C. Brase, Holger Fröhlich, Stephan Gade, Mathias Gehrmann, Maria Fälth, Holger Sültmann, Tim Beißbarth

    出版 2010
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  14. 14
    Artificial intelligence-based clustering and characterization of Parkinson's disease trajectories

    Artificial intelligence-based clustering and characterization of Parkinson's disease trajectories 由 Colin Birkenbihl, Ashar Ahmad, Nathalie J. Massat, Tamara Raschka, Andreja Avberšek, Patrick Downey, Martin Armstrong, Holger Fröhlich

    出版 2023
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  15. 15
    Progression subtypes in Parkinson’s disease identified by a data-driven multi cohort analysis

    Progression subtypes in Parkinson’s disease identified by a data-driven multi cohort analysis 由 Tom Hähnel, Tamara Raschka, Stefano Sapienza, Jochen Klucken, Enrico Glaab, Jean‐Christophe Corvol, Björn Falkenburger, Holger Fröhlich

    出版 2024
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  16. 16
    Improved prediction of MAPKi response duration in melanoma patients using genomic data and machine learning

    Improved prediction of MAPKi response duration in melanoma patients using genomic data and machine learning 由 Sarah Dandou, Kriti Amin, Véronique D’Hondt, Jérôme Solassol, O. Dereure, Peter J. Coopman, Ovidiu Radulescu, Holger Fröhlich, Romain M. Larive

    出版 2025
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  17. 17
    Ten quick tips for biomarker discovery and validation analyses using machine learning

    Ten quick tips for biomarker discovery and validation analyses using machine learning 由 Ramón Díaz‐Uriarte, Elisa Gómez de Lope, Rosalba Giugno, Holger Fröhlich, Petr V. Nazarov, Isabel A. Nepomuceno-Chamorro, Armin Rauschenberger, Enrico Glaab

    出版 2022
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  18. 18
    Stimulation of MMP-1 and CCL2 by NAMPT in PDL Cells

    Stimulation of MMP-1 and CCL2 by NAMPT in PDL Cells 由 Marjan Nokhbehsaim, Sigrun Eick, Andressa Vilas Boas Nogueira, Per Hoffmann, Stefan Herms, Holger Fröhlich, Søren Jepsen, Andreas Jäger, Joni Augusto Cirelli, James Deschner

    出版 2013
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  19. 19
    DNA methylation signature in peripheral blood reveals distinct characteristics of human X chromosome numerical aberrations

    DNA methylation signature in peripheral blood reveals distinct characteristics of human X chromosome numerical aberrations 由 Amit Sharma, Muhammad Ahmer Jamil, Nicole Nuesgen, Felix Schreiner, Lutz Priebe, Per Hoffmann, Stefan Herns, Markus M. Nöthen, Holger Fröhlich, Johannes Oldenburg, Joachim Woelfle, Osman El‐Maarri

    出版 2015
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  20. 20
    Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance

    Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance 由 Özgür Şahin, Holger Fröhlich, Christian Löbke, Ulrike Korf, Sara Burmester, Meher Majety, Jens Mattern, Ingo Schupp, Claudine Chaouiya, Denis Thieffry, Annemarie Poustka, Stefan Wiemann, Tim Beißbarth, Dorit Arlt

    出版 2009
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