Search Results - Hironori Hayashi

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  1. 1
    Design Strategies of Fluorescent Biosensors Based on Biological Macromolecular Receptors

    Design Strategies of Fluorescent Biosensors Based on Biological Macromolecular Receptors by Kazuki Tainaka, Reiko Sakaguchi, Hironori Hayashi, Shun Nakano, Fong Fong Liew, Takashi Morii

    Published 2010
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  2. 2
    Mechanism of Darunavir (DRV)’s High Genetic Barrier to HIV-1 Resistance: A Key V32I Substitution in Protease Rarely Occurs, but Once It Occurs, It Predisposes HIV-1 To Develop DRV Resistance

    Mechanism of Darunavir (DRV)’s High Genetic Barrier to HIV-1 Resistance: A Key V32I Substitution in Protease Rarely Occurs, but Once It Occurs, It Predisposes HIV-1 To Develop DRV... by Manabu Aoki, Debananda Das, Hironori Hayashi, Hiromi Aoki-Ogata, Yuki Takamatsu, Arun K. Ghosh, Hiroaki Mitsuya

    Published 2018
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  3. 3
    Pioglitazone inhibits the proliferation and metastasis of human pancreatic cancer cells

    Pioglitazone inhibits the proliferation and metastasis of human pancreatic cancer cells by Itasu Ninomiya, Keisuke Yamazaki, Katsunobu Oyama, Hironori Hayashi, Hidehiro Tajima, Hirohisa Kitagawa, Sachio Fushida, Takashi Fujimura, Tetsuo Ohta

    Published 2014
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  4. 4
    Aldosterone Nongenomically Produces NADPH Oxidase−Dependent Reactive Oxygen Species and Induces Myocyte Apoptosis

    Aldosterone Nongenomically Produces NADPH Oxidase−Dependent Reactive Oxygen Species and Induces Myocyte Apoptosis by Hironori Hayashi, Miyuki Kobara, Masaki Abe, Nana Tanaka, Eri Gouda, Hiroe Toba, Hiroyuki Yamada, Tetsuya Tatsumi, Tetsuo Nakata, Hiroaki Matsubara

    Published 2008
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  5. 5
    Dimerization of HIV-1 protease occurs through two steps relating to the mechanism of protease dimerization inhibition by darunavir

    Dimerization of HIV-1 protease occurs through two steps relating to the mechanism of protease dimerization inhibition by darunavir by Hironori Hayashi, Nobutoki Takamune, Takashi Nirasawa, Manabu Aoki, Yoshihiko Morishita, Debananda Das, Yasuhiro Koh, Arun K. Ghosh, Shogo Misumi, Hiroaki Mitsuya

    Published 2014
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  6. 6
    Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor

    Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor by Hironori Hayashi, Masatoshi Ichihara, Toshihide Iwashita, Hideki Murakami, Yohei Shimono, Kazuyoshi Kawai, Kazuo Kurokawa, Yoshiki Murakumo, Tsuneo Imai, Hiroomi Funahashi, Akimasa Nakao, Masahide Takahashi

    Published 2000
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  7. 7
    Platelets surrounding primary tumor cells are related to chemoresistance

    Platelets surrounding primary tumor cells are related to chemoresistance by Satoko Ishikawa, Tomoharu Miyashita, Masafumi Inokuchi, Hironori Hayashi, Katsunobu Oyama, Hidehiro Tajima, Hironori Takamura, Itasu Ninomiya, Ali Ahmed, John W. Harman, Sachio Fushida, Tetsuo Ohta

    Published 2016
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  8. 8
    Valproic acid inhibits proliferation of HER2-expressing breast cancer cells by inducing cell cycle arrest and apoptosis through Hsp70 acetylation

    Valproic acid inhibits proliferation of HER2-expressing breast cancer cells by inducing cell cycle arrest and apoptosis through Hsp70 acetylation by Toshiki Mawatari, Itasu Ninomiya, Masafumi Inokuchi, Shinichi Harada, Hironori Hayashi, Katsunobu Oyama, Isamu Makino, Hisatoshi Nakagawara, Tomoharu Miyashita, Hidehiro Tajima, Hiroyuki Takamura, Sachio Fushida, Tetsuo Ohta

    Published 2015
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  9. 9
    Ischemia reperfusion-facilitated sinusoidal endothelial cell injury in liver transplantation and the resulting impact of extravasated platelet aggregation

    Ischemia reperfusion-facilitated sinusoidal endothelial cell injury in liver transplantation and the resulting impact of extravasated platelet aggregation by Tomoharu Miyashita, Shinichi Nakanuma, Ali Ahmed, Isamu Makino, Hironori Hayashi, Katsunobu Oyama, Hisatoshi Nakagawara, Hidehiro Tajima, Hiroyuki Takamura, Itasu Ninomiya, Sachio Fushida, John W. Harmon, Takahisa Ohta

    Published 2015
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  10. 10
    Single atom changes in newly synthesized HIV protease inhibitors reveal structural basis for extreme affinity, high genetic barrier, and adaptation to the HIV protease plasticity

    Single atom changes in newly synthesized HIV protease inhibitors reveal structural basis for extreme affinity, high genetic barrier, and adaptation to the HIV protease plasticity by Haydar Bulut, Shin‐ichiro Hattori, Hiromi Aoki-Ogata, Hironori Hayashi, Debananda Das, Manabu Aoki, David A. Davis, Kalapala Venkateswara Rao, Prasanth R. Nyalapatla, Arun K. Ghosh, Hiroaki Mitsuya

    Published 2020
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  11. 11
    Neoadjuvant Chemotherapy with Gemcitabine Plus Nab-paclitaxel Reduces the Number of Cancer-associated Fibroblasts Through Depletion of Pancreatic Stroma

    Neoadjuvant Chemotherapy with Gemcitabine Plus Nab-paclitaxel Reduces the Number of Cancer-associated Fibroblasts Through Depletion of Pancreatic Stroma by Tomoharu Miyashita, Hidehiro Tajima, Isamu Makino, Mitsuyoshi Okazaki, Takahisa Yamaguchi, Yoshinao Ohbatake, Shinichi Nakanuma, Hironori Hayashi, Hiroyuki Takamura, Itasu Ninomiya, Sachio Fushida, Koji Kishimoto, John W. Harmon, Tetsuo Ohta

    Published 2018
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  12. 12
    Probiotic Beverage with Soy Isoflavone Consumption for Breast Cancer Prevention: A Case-control Study

    Probiotic Beverage with Soy Isoflavone Consumption for Breast Cancer Prevention: A Case-control Study by Masakazu Toi, Saya Hirota, Ai Tomotaki, Nobuaki Sato, Yasuo Hozumi, Keisei Anan, Takeshi Nagashima, Yutaka Tokuda, Norikazu Masuda, Shozo Ohsumi, Shinji Ohno, Masato Takahashi, Hironori Hayashi, Seiichiro Yamamoto, Yasuo Ohashi

    Published 2013
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  13. 13
    Design and Development of Highly Potent HIV-1 Protease Inhibitors with a Crown-Like Oxotricyclic Core as the P2-Ligand To Combat Multidrug-Resistant HIV Variants

    Design and Development of Highly Potent HIV-1 Protease Inhibitors with a Crown-Like Oxotricyclic Core as the P2-Ligand To Combat Multidrug-Resistant HIV Variants by Arun K. Ghosh, Kalapala Venkateswara Rao, Prasanth R. Nyalapatla, Heather L. Osswald, Cuthbert D. Martyr, Manabu Aoki, Hironori Hayashi, Johnson Agniswamy, Yuan-Fang Wang, Haydar Bulut, Debananda Das, Irene T. Weber, Hiroaki Mitsuya

    Published 2017
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  14. 14
    Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones

    Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones by Kento Tsukada, Shono Shinki, Akiho Kaneko, Kazuma Murakami, Kazuhiro Irie, Masatoshi Murai, Hideto Miyoshi, Shingo Dan, Kumi Kawaji, Hironori Hayashi, Eiichi Kodama, Aki Hori, Emil Salim, Takayuki Kuraishi, Naoya Hirata, Yasunari Kanda, Teigo Asai

    Published 2020
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  15. 15
    Serine hydroxymethyltransferase as a potential target of antibacterial agents acting synergistically with one-carbon metabolism-related inhibitors

    Serine hydroxymethyltransferase as a potential target of antibacterial agents acting synergistically with one-carbon metabolism-related inhibitors by Yuko Makino, Chihiro Oe, Kazuya Iwama, Satoshi Suzuki, Akie Nishiyama, Kazuya Hasegawa, Haruka Okuda, Kazushige Hirata, Mariko Ueno, Kumi Kawaji, Mina Sasano, Emiko Usui, Toshiaki Hosaka, Yukako Yabuki, Mikako Shirouzu, Makoto Katsumi, Kazutaka Murayama, Hironori Hayashi, Eiichi Kodama

    Published 2022
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  16. 16
    Pilot study of neoadjuvant chemotherapy with gemcitabine and oral S-1 for resectable pancreatic cancer

    Pilot study of neoadjuvant chemotherapy with gemcitabine and oral S-1 for resectable pancreatic cancer by Hidehiro Tajima, Tetsuo Ohta, Hirohisa Kitagawa, Koichi Okamoto, Seisho Sakai, Isamu Makino, Jun Kinoshita, Hiroyuki Furukawa, Keishi Nakamura, Hironori Hayashi, Katsunobu Oyama, Masafumi Inokuchi, Hisatoshi Nakagawara, Hideto Fujita, Hiroyuki Takamura, Itasu Ninomiya, Sachio Fushida, Takashi Tani, Takashi Fujimura, Hiroko Ikeda, S Kitamura

    Published 2012
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  17. 17
    Angiotensin II enhances epithelial-to-mesenchymal transition through the interaction between activated hepatic stellate cells and the stromal cell-derived factor-1/CXCR4 axis in intrahepatic cholangiocarcinoma

    Angiotensin II enhances epithelial-to-mesenchymal transition through the interaction between activated hepatic stellate cells and the stromal cell-derived factor-1/CXCR4 axis in in... by Koichi Okamoto, Hidehiro Tajima, Shinichi Nakanuma, Seisho Sakai, Isamu Makino, Jun Kinoshita, Hironori Hayashi, Keishi Nakamura, Katsunobu Oyama, Hisatoshi Nakagawara, Hideto Fujita, Hiroyuki Takamura, Itasu Ninomiya, Hirohisa Kitagawa, Sachio Fushida, Takashi Fujimura, Shinichi Harada, Tomohiko Wakayama, Shoichi Iseki, Tetsuo Ohta

    Published 2012
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  18. 18
    Role for Neutrophil Extracellular Traps (NETs) and Platelet Aggregation in Early Sepsis-induced Hepatic Dysfunction

    Role for Neutrophil Extracellular Traps (NETs) and Platelet Aggregation in Early Sepsis-induced Hepatic Dysfunction by Kentaro Sakurai, Tomoharu Miyashita, Mitsuyoshi Okazaki, Takahisa Yamaguchi, Yoshinao Ohbatake, Shinichi Nakanuma, Koichi Okamoto, Seisho Sakai, Jun Kinoshita, Isamu Makino, Keishi Nakamura, Hironori Hayashi, Katsunobu Oyama, Hidehiro Tajima, Hiroyuki Takamura, Itasu Ninomiya, Sachio Fushida, Kenichi Harada, John W. Harmon, Tetsuo Ohta

    Published 2017
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  19. 19
    Comparative study of the antitumor activity of Nab-paclitaxel and intraperitoneal solvent-based paclitaxel regarding peritoneal metastasis in gastric cancer

    Comparative study of the antitumor activity of Nab-paclitaxel and intraperitoneal solvent-based paclitaxel regarding peritoneal metastasis in gastric cancer by Jun Kinoshita, Sachio Fushida, Tomoya Tsukada, Katsunobu Oyama, Toshihumi Watanabe, Masatoshi Shoji, Koichi Okamoto, Shinichi Nakanuma, Seisho Sakai, Isamu Makino, Hiroyuki Furukawa, Hironori Hayashi, Keishi Nakamura, Masahumi Inokuchi, Hisatoshi Nakagawara, Tomoharu Miyashita, Hidehiro Tajima, Hiroyuki Takamura, Itasu Ninomiya, Takashi Fujimura, Masakazu Yashiro, Kosei Hirakawa, Tetsuo Ohta

    Published 2014
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  20. 20
    A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency

    A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency by Manabu Aoki, Hironori Hayashi, Kalapala Venkateswara Rao, Debananda Das, Nobuyo Higashi‐Kuwata, Haydar Bulut, Hiromi Aoki-Ogata, Yuki Takamatsu, Ravikiran S. Yedidi, David A. Davis, Shin-ichiro Hattori, Noriko Nishida, Kazuya Hasegawa, Nobutoki Takamune, Prasanth R. Nyalapatla, Heather L. Osswald, Hirofumi Jono, Hideyuki Saito, Robert Yarchoan, Shogo Misumi, Arun K. Ghosh, Hiroaki Mitsuya

    Published 2017
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