Rezultaty - Hermela Shimelis

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  1. 1
    The 44-kDa Pim-1 Kinase Phosphorylates BCRP/ABCG2 and Thereby Promotes Its Multimerization and Drug-resistant Activity in Human Prostate Cancer Cells

    The 44-kDa Pim-1 Kinase Phosphorylates BCRP/ABCG2 and Thereby Promotes Its Multimerization and Drug-resistant Activity in Human Prostate Cancer Cells od Yingqiu Xie, Kexin Xu, Douglas E. Linn, Xi Yang, Zhiyong Guo, Hermela Shimelis, Takeo Nakanishi, Douglas D. Ross, Hegang Chen, Ladan Fazli, Martin Gleave, Yun Qiu

    Wydane 2007
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  2. 2
    Male breast cancer in a multi-gene panel testing cohort: insights and unexpected results

    Male breast cancer in a multi-gene panel testing cohort: insights and unexpected results od Mary Pritzlaff, Pia Summerour, Rachel McFarland, Shuwei Li, Patrick Reineke, Jill S. Dolinsky, David E. Goldgar, Hermela Shimelis, Fergus J. Couch, Elizabeth Chao, Holly LaDuca

    Wydane 2016
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  3. 3
    Frequency of mutations in a large series of clinically ascertained ovarian cancer cases tested on multi-gene panels compared to reference controls

    Frequency of mutations in a large series of clinically ascertained ovarian cancer cases tested on multi-gene panels compared to reference controls od Jenna Lilyquist, Holly LaDuca, Eric C. Polley, Brigette Tippin Davis, Hermela Shimelis, Chunling Hu, Steven N. Hart, Jill S. Dolinsky, Fergus J. Couch, David E. Goldgar

    Wydane 2017
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  4. 4
    Novel Membrane-associated Androgen Receptor Splice Variant Potentiates Proliferative and Survival Responses in Prostate Cancer Cells

    Novel Membrane-associated Androgen Receptor Splice Variant Potentiates Proliferative and Survival Responses in Prostate Cancer Cells od Xi Yang, Zhiyong Guo, Feng Sun, Wěi Li, Alan P. Alfano, Hermela Shimelis, Ming‐Yuan Chen, Angela Brodie, Hegang Chen, Zhen Xiao, Timothy D. Veenstra, Yun Qiu

    Wydane 2011
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  5. 5
    Differential Regulation of Androgen Receptor by PIM-1 Kinases via Phosphorylation-dependent Recruitment of Distinct Ubiquitin E3 Ligases

    Differential Regulation of Androgen Receptor by PIM-1 Kinases via Phosphorylation-dependent Recruitment of Distinct Ubiquitin E3 Ligases od Douglas E. Linn, Xi Yang, Yingqiu Xie, Alan P. Alfano, Dhanraj Deshmukh, Xin Wang, Hermela Shimelis, Hegang Chen, Wěi Li, Kexin Xu, Ming‐Yuan Chen, Yun Qiu

    Wydane 2012
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  6. 6
    The Contribution of Germline Predisposition Gene Mutations to Clinical Subtypes of Invasive Breast Cancer From a Clinical Genetic Testing Cohort

    The Contribution of Germline Predisposition Gene Mutations to Clinical Subtypes of Invasive Breast Cancer From a Clinical Genetic Testing Cohort od Chunling Hu, Eric C. Polley, Siddhartha Yadav, Jenna Lilyquist, Hermela Shimelis, Jie Na, Steven N. Hart, David E. Goldgar, Swati Shah, Tina Pesaran, Jill S. Dolinsky, Holly LaDuca, Fergus J. Couch

    Wydane 2020
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  7. 7
    Assessment of the Clinical Relevance of BRCA2 Missense Variants by Functional and Computational Approaches

    Assessment of the Clinical Relevance of BRCA2 Missense Variants by Functional and Computational Approaches od Lucia Guidugli, Hermela Shimelis, David L. Masica, V. Shane Pankratz, Gary Lipton, Namit Singh, Chunling Hu, Álvaro N.A. Monteiro, Noralane M. Lindor, David E. Goldgar, Rachel Karchin, Edwin S. Iversen, Fergus J. Couch

    Wydane 2018
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  8. 8
    Regulation of Androgen Receptor Transcriptional Activity and Specificity by RNF6-Induced Ubiquitination

    Regulation of Androgen Receptor Transcriptional Activity and Specificity by RNF6-Induced Ubiquitination od Kexin Xu, Hermela Shimelis, Douglas E. Linn, Richeng Jiang, Xi Yang, Feng Sun, Zhiyong Guo, Hege Chen, Wei Li, Hegang Chen, Xiangtian Kong, Jonathan Melamed, Shengyun Fang, Zhen Xiao, Timothy D. Veenstra, Yun Qiu

    Wydane 2009
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  9. 9
    Clinical validity assessment of genes frequently tested on hereditary breast and ovarian cancer susceptibility sequencing panels

    Clinical validity assessment of genes frequently tested on hereditary breast and ovarian cancer susceptibility sequencing panels od Kristy Lee, Bryce A. Seifert, Hermela Shimelis, Rajarshi Ghosh, Stephanie B. Crowley, Natalie J. Carter, Kurston Doonanco, Ann Katherine M. Foreman, Deborah Ritter, Sharisse Jimenez, Mackenzie Trapp, Kenneth Offit, Sharon E. Plon, Fergus J. Couch

    Wydane 2018
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  10. 10
    Comprehensive annotation of BRCA1 and BRCA2 missense variants by functionally validated sequence-based computational prediction models

    Comprehensive annotation of BRCA1 and BRCA2 missense variants by functionally validated sequence-based computational prediction models od Steven N. Hart, Tanya L. Hoskin, Hermela Shimelis, Raymond M. Moore, Bing Feng, Abigail Thomas, Noralane M. Lindor, Eric C. Polley, David E. Goldgar, Edwin S. Iversen, Álvaro N.A. Monteiro, Vera J. Suman, Fergus J. Couch

    Wydane 2018
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  11. 11
    Multigene Hereditary Cancer Panels Reveal High-Risk Pancreatic Cancer Susceptibility Genes

    Multigene Hereditary Cancer Panels Reveal High-Risk Pancreatic Cancer Susceptibility Genes od Chunling Hu, Holly LaDuca, Hermela Shimelis, Eric C. Polley, Jenna Lilyquist, Steven N. Hart, Jie Na, Abigail Thomas, Kun Y. Lee, Brigette Tippin Davis, Mary Helen Black, Tina Pesaran, David E. Goldgar, Jill S. Dolinsky, Fergus J. Couch

    Wydane 2018
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  12. 12
    Exome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancer

    Exome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancer od Johanna I. Kiiski, Liisa M. Pelttari, Sofia Khan, Edda Sigríður Freysteinsdóttir, Inga Reynisdóttir, Steven N. Hart, Hermela Shimelis, Sara Vilske, Anne Kallioniemi, Johanna Schleutker, Arto Leminen, Ralf Bützow, Carl Blomqvist, Rósa B. Barkardóttir, Fergus J. Couch, Kristiina Aittomäki, Heli Nevanlinna

    Wydane 2014
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  13. 13
    Associations Between Cancer Predisposition Testing Panel Genes and Breast Cancer

    Associations Between Cancer Predisposition Testing Panel Genes and Breast Cancer od Fergus J. Couch, Hermela Shimelis, Chunling Hu, Steven N. Hart, Eric C. Polley, Jie Na, Emily Hallberg, Raymond M. Moore, Abigail Thomas, Jenna Lilyquist, Bing Feng, Rachel McFarland, Tina Pesaran, Robert Huether, Holly LaDuca, Elizabeth Chao, David E. Goldgar, Jill S. Dolinsky

    Wydane 2017
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  14. 14
    Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer

    Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer od Chunling Hu, Steven N. Hart, Eric C. Polley, Rohan Gnanaolivu, Hermela Shimelis, Kun Y. Lee, Jenna Lilyquist, Jie Na, Raymond M. Moore, Samuel O. Antwi, William R. Bamlet, Kari G. Chaffee, John DiCarlo, Zhong Wu, Raed Samara, Pashtoon Murtaza Kasi, Robert R. McWilliams, Gloria M. Petersen, Fergus J. Couch

    Wydane 2018
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  15. 15
    <i>BRCA1/2</i> Mutations and Bevacizumab in the Neoadjuvant Treatment of Breast Cancer: Response and Prognosis Results in Patients With Triple-Negative Breast Cancer From the GeparQuinto Study

    <i>BRCA1/2</i> Mutations and Bevacizumab in the Neoadjuvant Treatment of Breast Cancer: Response and Prognosis Results in Patients With Triple-Negative Breast Cancer From the Gepar... od Peter A. Fasching, Sibylle Loibl, Chunling Hu, Steven N. Hart, Hermela Shimelis, Raymond M. Moore, Christian Schem, Hans Tesch, Michael Untch, J. Hilfrich, Mahdi Rezai, Bernd Gerber, Serban Dan Costa, Jens‐Uwe Blohmer, Tanja Fehm, Jens Huober, Cornelia Liedtke, Richard M. Weinshilboum, Liewei Wang, James N. Ingle, Volkmar Müller, Valentina Nekljudova, Karsten E. Weber, Brigitte Rack, Matthias Rübner, Gϋnter von Minckwitz, Fergus J. Couch

    Wydane 2018
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  16. 16
    Triple-Negative Breast Cancer Risk Genes Identified by Multigene Hereditary Cancer Panel Testing

    Triple-Negative Breast Cancer Risk Genes Identified by Multigene Hereditary Cancer Panel Testing od Hermela Shimelis, Holly LaDuca, Chunling Hu, Steven N. Hart, Jie Na, Abigail Thomas, Margaret Akinhanmi, Raymond M. Moore, Hiltrud Brauch, Angela Cox, Diana Eccles, Amanda E. Toland, Peter A. Fasching, Florentia Fostira, Judy E. Garber, Andrew K. Godwin, Irene Konstantopoulou, Heli Nevanlinna, Priyanka Sharma, Drakoulis Yannoukakos, Song Yao, Bing Feng, Brigette Tippin Davis, Jenna Lilyquist, Tina Pesaran, David E. Goldgar, Eric C. Polley, Jill S. Dolinsky, Fergus J. Couch

    Wydane 2018
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  17. 17
    <i>BRCA2</i> Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer

    <i>BRCA2</i> Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer od Hermela Shimelis, Romy L.S. Mesman, Catharina Von Nicolai, Åsa Ehlén, Lucia Guidugli, Charlotte Martin, Fabienne M.G.R. Calléja, Huong Meeks, Emily Hallberg, Jamie Hinton, Jenna Lilyquist, Chunling Hu, Cora M. Aalfs, Kristiina Aittomäki, Irene L. Andrulis, Hoda Anton‐Culver, Volker Arndt, Matthias W. Beckmann, Javier Benı́tez, Natalia Bogdanova, Stig E. Bojesen, Manjeet K. Bolla, Anne‐Lise Børresen‐Dale, Hiltrud Brauch, Paul Brennan, Hermann Brenner, Annegien Broeks, Barbara Brouwers, Thomas Brüning, Barbara Burwinkel, Jenny Chang‐Claude, Georgia Chenevix‐Trench, Ching‐Yu Cheng, Ji‐Yeob Choi, J. Margriet Collée, Angela Cox, Simon S. Cross, Kamila Czene, Hatef Darabi, Joe Dennis, Thilo Dörk, Isabel dos–Santos–Silva, Alison M. Dunning, Peter A. Fasching, Jonine D. Figueroa, Henrik Flyger, Montserrat García‐Closas, Graham G. Giles, Gord Glendon, Pascal Guénel, Christopher A. Haiman, Per Hall, Ute Hamann, Mikael Hartman, Frans B.L. Hogervorst, Antoinette Hollestelle, John L. Hopper, Hidemi Ito, Anna Jakubowska, Daehee Kang, Veli‐Matti Kosma, Vessela N. Kristensen, Kah-Nyin Lai, Diether Lambrechts, Loı̈c Le Marchand, Jingmei Li, Annika Lindblom, Artitaya Lophatananon, Jan Lubiński, Eva Macháčková, Graham J. Mann, Sara Margolin, Frederik Marmé, Keitaro Matsuo, Hui Miao, Kyriaki Michailidou, Roger L. Milne, Kenneth Muir, Susan L. Neuhausen, Heli Nevanlinna, Janet E. Olson, Curtis Olswold, Jan J.C. Oosterwijk, Ana Osório, Paolo Peterlongo, Julian Peto, Paul D.P. Pharoah, Katri Pylkäs, Paolo Radice, Muhammad Usman Rashid, Valerie Rhenius, Anja Rudolph, Suleeporn Sangrajrang, Elinor J. Sawyer, Marjanka K. Schmidt, Minouk J. Schoemaker, Caroline Seynaeve, Mitul Shah, Chen‐Yang Shen, Martha J. Shrubsole

    Wydane 2017
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