檢索結果 - Henry J. Lin

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  1. 1
    Targeting the cancer kinome through polypharmacology

    Targeting the cancer kinome through polypharmacology 由 Zachary A. Knight, Henry J. Lin, Kevan M. Shokat

    出版 2010
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  2. 2
    In search of druggable targets for GBM amino acid metabolism

    In search of druggable targets for GBM amino acid metabolism 由 Eduard H. Panosyan, Henry J. Lin, Jan Köster, Joseph L. Lasky

    出版 2017
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  3. 3
    A pharmacological organization of G protein–coupled receptors

    A pharmacological organization of G protein–coupled receptors 由 Henry J. Lin, Maria F. Sassano, Bryan L. Roth, Brian K. Shoichet

    出版 2013
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  4. 4
    Deficits in cortical, diencephalic and midbrain gray matter in alcoholism measured by VBM: Effects of co-morbid substance abuse

    Deficits in cortical, diencephalic and midbrain gray matter in alcoholism measured by VBM: Effects of co-morbid substance abuse 由 Erica N. Grodin, Henry J. Lin, Caitlin A. Durkee, Daniel W. Hommer, Reza Momenan

    出版 2013
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  5. 5
    Oxygen environment and islet size are the primary limiting factors of isolated pancreatic islet survival

    Oxygen environment and islet size are the primary limiting factors of isolated pancreatic islet survival 由 Hirotake Komatsu, Colin A. Cook, Chia-Hao Wang, Leonard Medrano, Henry J. Lin, Fouad Kandeel, Yu‐Chong Tai, Yoko Mullen

    出版 2017
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  6. 6
    Specific Inhibition of p97/VCP ATPase and Kinetic Analysis Demonstrate Interaction between D1 and D2 ATPase Domains

    Specific Inhibition of p97/VCP ATPase and Kinetic Analysis Demonstrate Interaction between D1 and D2 ATPase Domains 由 Tsui‐Fen Chou, Stacie L. Bulfer, Conrad C. Weihl, Kelin Li, Lev Lis, Michael A. Walters, Frank J. Schoenen, Henry J. Lin, Raymond J. Deshaies, Michelle R. Arkin

    出版 2014
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  7. 7
    Asparagine Depletion Potentiates the Cytotoxic Effect of Chemotherapy against Brain Tumors

    Asparagine Depletion Potentiates the Cytotoxic Effect of Chemotherapy against Brain Tumors 由 Eduard H. Panosyan, Yuntao Wang, Peng Xia, Wai‐Nang Paul Lee, Youngju Pak, Dan R. Laks, Henry J. Lin, Theodore B. Moore, Timothy F. Cloughesy, Harley I. Kornblum, Joseph L. Lasky

    出版 2014
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  8. 8
    Altered cofactor regulation with disease-associated p97/VCP mutations

    Altered cofactor regulation with disease-associated p97/VCP mutations 由 Xiaoyi Zhang, Lin Gui, Xiaoyan Zhang, Stacie L. Bulfer, Valentina Sanghez, Daniel Wong, Youjin Lee, Lynn Lehmann, James S. Lee, Pei-Yin Shih, Henry J. Lin, Michelina Iacovino, Conrad C. Weihl, Michelle R. Arkin, Yanzhuang Wang, Tsui‐Fen Chou

    出版 2015
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  9. 9
    Genome-wide analyses identify SCN5A as a susceptibility locus for premature atrial contraction frequency

    Genome-wide analyses identify SCN5A as a susceptibility locus for premature atrial contraction frequency 由 Sébastien Thériault, Medea Imboden, Mary L. Biggs, Thomas R. Austin, Stefanie Aeschbacher, Emmanuel Schaffner, Jennifer A. Brody, Traci M. Bartz, Martin Risch, Kirsten Grossmann, Henry J. Lin, Elsayed Z. Soliman, Wendy S. Post, Lorenz Risch, José Eduardo Krieger, Alexandre C. Pereira, Susan R. Heckbert, Nona Sotoodehnia, Nicole Probst‐Hensch, David Conen

    出版 2022
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  10. 10
    Structure-based discovery of opioid analgesics with reduced side effects

    Structure-based discovery of opioid analgesics with reduced side effects 由 Aashish Manglik, Henry J. Lin, Dipendra K. Aryal, John D. McCorvy, Daniela G. Dengler, Gregory Corder, Anat Levit, Ralf C. Kling, Viachaslau Bernat, Harald Hübner, Xi‐Ping Huang, Maria F. Sassano, Patrick M. Giguère, Stefan Löber, Da Duan, Grégory Scherrer, Brian K. Kobilka, Peter Gmeiner, Bryan L. Roth, Brian K. Shoichet

    出版 2016
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  11. 11
    Non-linear machine learning models incorporating SNPs and PRS improve polygenic prediction in diverse human populations

    Non-linear machine learning models incorporating SNPs and PRS improve polygenic prediction in diverse human populations 由 Michael Elgart, Genevieve Lyons, Santiago Romero‐Brufau, Nuzulul Kurniansyah, Jennifer A. Brody, Xiuqing Guo, Henry J. Lin, Laura M. Raffield, Yan Gao, Han Chen, Paul S. de Vries, Donald M. Lloyd‐Jones, Leslie A. Lange, Gina M. Peloso, Myriam Fornage, Jerome I. Rotter, Stephen S. Rich, Alanna C. Morrison, Bruce M. Psaty, Daniel Levy, Susan Redline, Paul S. de Vries, Tamar Sofer

    出版 2022
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  12. 12
    A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood

    A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood 由 Nuzulul Kurniansyah, Matthew Goodman, Tanika N. Kelly, Tali Elfassy, Kerri L. Wiggins, Joshua C. Bis, Xiuqing Guo, Walter Palmas, Kent D. Taylor, Henry J. Lin, Jeffrey Haessler, Yan Gao, Daichi Shimbo, Jennifer A. Smith, Bing Yu, Elena V. Feofanova, Roelof A.J. Smit, Zhe Wang, Shih‐Jen Hwang, Simin Liu, Sylvia Wassertheil‐Smoller, JoAnn E. Manson, Donald M. Lloyd‐Jones, Stephen S. Rich, Ruth J. F. Loos, Susan Redline, Adolfo Correa, Charles Kooperberg, Myriam Fornage, Robert C. Kaplan, Bruce M. Psaty, Jerome I. Rotter, Donna K. Arnett, Alanna C. Morrison, Nora Franceschini, Daniel Levy, Joshua C. Bis, Xiuqing Guo, Kent D. Taylor, Henry J. Lin, Jeffrey Haessler, Yan Gao, Jennifer A. Smith, Simin Liu, Sylvia Wassertheil‐Smoller, JoAnn E. Manson, Stephen S. Rich, Susan Redline, Adolfo Correa, Charles Kooperberg, Myriam Fornage, Robert C. Kaplan, Bruce M. Psaty, Jerome I. Rotter, Donna K. Arnett, Nora Franceschini, Daniel Levy, Tamar Sofer, Tamar Sofer

    出版 2022
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  13. 13
    De novo truncating variants in the intronless IRF2BPL are responsible for developmental epileptic encephalopathy

    De novo truncating variants in the intronless IRF2BPL are responsible for developmental epileptic encephalopathy 由 Frédéric Tran Mau‐Them, Laurent Guibaud, Laurence Duplomb, Boris Keren, Kristin Lindstrom, Isabelle Marey, Fanny Mochel, M. J. van den Boogaard, Renske Oegema, Caroline Nava, Alice Masurel, Thibaud Jouan, Floor E. Jansen, Margaret Au, Agnes H. Chen, M. Cho, Yannis Duffourd, Ekaterina Lozier, Fedor A. Konovalov, Artem Sharkov, С. А. Коростелев, Benoit Urteaga, Patricia Dickson, M. Concepcion Nuñez Pardo de Vera, Julian A. Martínez‐Agosto, Anaïs Begemann, Markus Zweier, Thomas Schmitt‐Mechelke, Anita Rauch, Christophe Philippe, Koen L.I. van Gassen, S. F. Nelson, John M. Graham, Jennifer Friedman, Laurence Faivre, Henry J. Lin, Christel Thauvin‐Robinet, Antonio Vitobello

    出版 2018
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  14. 14
    Monogenic and Polygenic Contributions to QTc Prolongation in the Population

    Monogenic and Polygenic Contributions to QTc Prolongation in the Population 由 Victor Nauffal, Valerie N. Morrill, Sean J. Jurgens, Seung Hoan Choi, Amelia Weber Hall, Lu‐Chen Weng, Jennifer L. Halford, Christina Austin‐Tse, Christopher M. Haggerty, Stephanie Harris, Eugene Wong, Álvaro Alonso, Dan E. Arking, Emelia J. Benjamin, Eric Boerwinkle, Yuan‐I Min, Adolfo Correa, Brandon K. Fornwalt, Susan R. Heckbert, Charles Kooperberg, Henry J. Lin, Ruth J. F. Loos, Kenneth Rice, Namrata Gupta, Thomas W. Blackwell, Braxton D. Mitchell, Alanna C. Morrison, Bruce M. Psaty, Wendy S. Post, Susan Redline, Heidi L. Rehm, Stephen S. Rich, Jerome I. Rotter, Elsayed Z. Soliman, Nona Sotoodehnia, Kathryn L. Lunetta, Patrick T. Ellinor, Steven A. Lubitz

    出版 2022
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  15. 15
    Genetic Risk Prediction of Atrial Fibrillation

    Genetic Risk Prediction of Atrial Fibrillation 由 Steven A. Lubitz, Xiaoyan Yin, Henry J. Lin, Matthew J. Kolek, J. G. Smith, Stella Trompet, Michiel Rienstra, Natalia S. Rost, Pedro L. Teixeira, Peter Almgren, Christopher D. Anderson, Lin Y. Chen, Gunnar Engström, Ian Ford, Karen L. Furie, Xiuqing Guo, Martin G. Larson, Kathryn L. Lunetta, Peter W. Macfarlane, Bruce M. Psaty, Elsayed Z. Soliman, Nona Sotoodehnia, David J. Stott, Kent D. Taylor, Lu‐Chen Weng, Jie Yao, Bastiaan Geelhoed, Niek Verweij, Joylene E. Siland, Sekar Kathiresan, Carolina Roselli, Dan M. Roden, Pim van der Harst, Dawood Darbar, J. Wouter Jukema, Olle Melander, Jonathan Rosand, Jerome I. Rotter, Susan R. Heckbert, Patrick T. Ellinor, Álvaro Alonso, Emelia J. Benjamin

    出版 2016
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  16. 16
    Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation

    Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation 由 Christina Ellervik, Carolina Roselli, Ingrid E. Christophersen, Álvaro Alonso, Maik Pietzner, Collen M. Sitlani, Stella Trompet, Dan E. Arking, Bastiaan Geelhoed, Xiuqing Guo, Marcus E. Kleber, Henry J. Lin, Honghuang Lin, Peter W. Macfarlane, Elizabeth Selvin, Christian M. Shaffer, Albert V. Smith, Niek Verweij, Stefan Weiß, Anne Rentoumis Cappola, Marcus Dörr, Vilmundur Guðnason, Susan R. Heckbert, Simon P. Mooijaart, Winfried März, Bruce M. Psaty, Paul M. Ridker, Dan M. Roden, David J. Stott, Henry Völzke, Emelia J. Benjamin, Graciela Delgado, Patrick T. Ellinor, Georg Homuth, Anna Köttgen, J. Wouter Jukema, Steven A. Lubitz, Samia Mora, Michiel Rienstra, Jerome I. Rotter, M. Benjamin Shoemaker, Nona Sotoodehnia, Kent D. Taylor, Pim van der Harst, Christine M. Albert, Daniel I. Chasman

    出版 2019
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  17. 17
    An open resource of structural variation for medical and population genetics

    An open resource of structural variation for medical and population genetics 由 Ryan L. Collins, Harrison Brand, Konrad J. Karczewski, Xuefang Zhao, Jessica Alföldi, Laurent C. Francioli, Amit V. Khera, Chelsea Lowther, Laura D. Gauthier, Harold Wang, Nicholas A. Watts, Matthew Solomonson, Anne O’Donnell‐Luria, Alexander Baumann, Ruchi Munshi, Mark Walker, Christopher W. Whelan, Yongqing Huang, Ted Brookings, Ted Sharpe, Matthew R. Stone, Elise Valkanas, Jack Fu, Grace Tiao, Kristen M. Laricchia, Valentín Ruano-Rubio, Christine Stevens, Namrata Gupta, Lauren Margolin, Kent D. Taylor, Henry J. Lin, Stephen S. Rich, Wendy S. Post, Yii‐Der Ida Chen, Jerome I. Rotter, Chad Nusbaum, Anthony Philippakis, Eric S. Lander, Stacey Gabriel, Benjamin M. Neale, Sekar Kathiresan, Mark J. Daly, Eric Banks, Daniel G. MacArthur, Michael E. Talkowski

    出版 2019
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  18. 18
    Evaluating the use of blood pressure polygenic risk scores across race/ethnic background groups

    Evaluating the use of blood pressure polygenic risk scores across race/ethnic background groups 由 Nuzulul Kurniansyah, Matthew Goodman, Alyna Khan, Jiongming Wang, Elena V. Feofanova, Joshua C. Bis, Kerri L. Wiggins, Jennifer E. Huffman, Tanika N. Kelly, Tali Elfassy, Xiuqing Guo, Walter Palmas, Henry J. Lin, Shih‐Jen Hwang, Yan Gao, Kendra A. Young, Gregory L. Kinney, Jennifer A. Smith, Bing Yu, Simin Liu, Sylvia Wassertheil‐Smoller, JoAnn E. Manson, Xiaofeng Zhu, Yii‐Der Ida Chen, I‐Te Lee, C. Charles Gu, Donald M. Lloyd‐Jones, Sebastian Zöllner, Myriam Fornage, Charles Kooperberg, Adolfo Correa, Bruce M. Psaty, Donna K. Arnett, Carmen R. Isasi, Stephen S. Rich, Robert C. Kaplan, Susan Redline, Braxton D. Mitchell, Nora Franceschini, Daniel Levy, Jerome I. Rotter, Alanna C. Morrison, Tamar Sofer

    出版 2023
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  19. 19
    Genetic Determinants of Electrocardiographic P-Wave Duration and Relation to Atrial Fibrillation

    Genetic Determinants of Electrocardiographic P-Wave Duration and Relation to Atrial Fibrillation 由 Lu‐Chen Weng, Amelia Weber Hall, Seung Hoan Choi, Sean J. Jurgens, Jeffrey Haessler, Nathan A. Bihlmeyer, Niels Grarup, Honghuang Lin, Alexander Teumer, Ruifang Li‐Gao, Jie Yao, Xiuqing Guo, Jennifer A. Brody, Martina Müller‐Nurasyid, Katharina Schramm, Niek Verweij, Marten E. van den Berg, Jessica van Setten, Aaron Isaacs, Julia Ramírez, Helen R. Warren, Sandosh Padmanabhan, Jan A. Kors, Rudolf A. de Boer, Peter van der Meer, Moritz F. Sinner, Mélanie Waldenberger, Bruce M. Psaty, Kent D. Taylor, Uwe Völker, Jørgen K. Kanters, Man Li, Álvaro Alonso, Marco Pérez, Ilonca Vaartjes, Michiel L. Bots, Paul L. Huang, Susan R. Heckbert, Henry J. Lin, Jelena Kornej, Patricia B. Munroe, Cornelia M. van Duijn, Folkert W. Asselbergs, Bruno H. Stricker, Pim van der Harst, Stefan Kääb, Annette Peters, Nona Sotoodehnia, Jerome I. Rotter, Dennis O. Mook‐Kanamori, Marcus Dörr, Stephan B. Felix, Allan Linneberg, Torben Hansen, Dan E. Arking, Charles Kooperberg, Emelia J. Benjamin, Kathryn L. Lunetta, Patrick T. Ellinor, Steven A. Lubitz

    出版 2020
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  20. 20
    Genetic analyses of the QT interval and its components in over 250K individuals identifies new loci and pathways affecting ventricular depolarization and repolarization

    Genetic analyses of the QT interval and its components in over 250K individuals identifies new loci and pathways affecting ventricular depolarization and repolarization 由 William J. Young, Najim Lahrouchi, Aaron Isaacs, ThuyVy Duong, Luisa Foco, Farah Ahmed, Jennifer A. Brody, Reem Salman, Raymond Noordam, Jan Walter Benjamins, Jeffrey Haessler, Leo‐Pekka Lyytikäinen, L. Repetto, Maria Pina Concas, Marten E. van den Berg, Stefan Weiß, Antoine Baldassari, Traci M. Bartz, James P. Cook, Daniel S. Evans, Rebecca Freudling, Oliver Hines, Jonas L. Isaksen, Honghuang Lin, Hao Mei, Arden Moscati, Martina Müller‐Nurasyid, Casia Nursyifa, Yong Qian, Anne Richmond, Carolina Roselli, Kathleen A. Ryan, Eduardo Tarazona‐Santos, Sébastien Thériault, Stefan van Duijvenboden, Helen Warren, Jie Yao, Dania Raza, Stefanie Aeschbacher, Gustav Ahlberg, Álvaro Alonso, Laura Andreasen, Joshua C. Bis, Eric Boerwinkle, Archie Campbell, Eulalia Catamo, Massimiliano Cocca, Michael J. Cutler, Dawood Darbar, Alessandro De Grandi, Antonio De Luca, Jun Ding, Christina Ellervik, Patrick T. Ellinor, Stephan B. Felix, Philippe Froguel, Christian Fuchsberger, Martin Gögele, Claus Graff, Mariaelisa Graff, Xiuqing Guo, Torben Hansen, Susan R. Heckbert, Paul L. Huang, Heikki V. Huikuri, Nina Hutri‐Kähönen, M. Arfan Ikram, Rebecca D. Jackson, Juhani Junttila, Maryam Kavousi, Jan A. Kors, Thiago Peixoto Leal, Rozenn N. Lemaître, Henry J. Lin, Lars Lind, Allan Linneberg, Simin Liu, Peter W. Macfarlane, Massimo Mangino, Thomas Meitinger, Massimo Mezzavilla, Pashupati P. Mishra, Rebecca Mitchell, Nina Mononen, May E. Montasser, Alanna C. Morrison, Matthias Nauck, Victor Nauffal, Pau Navarro, Kjell Nikus, Guillaume Paré, Kristen K. Patton, Giulia Pelliccione, Alan Pittman, David J. Porteous, Peter P. Pramstaller, Michael Preuß, Olli T. Raitakari, Alexander P. Reiner, Antônio Luiz Pinho Ribeiro

    出版 2021
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