Ohcanbohtosat - Henrik Möbitz
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1
Optimization of a Fragment-Based Screening Hit toward Potent DOT1L Inhibitors Interacting in an Induced Binding Pocket Dahkki Clemens Scheufler, Henrik Möbitz, Christoph Gaul, Christian Ragot, C. Be, César Fernández Fernández, Kim S. Beyer, Ralph Tiedt, Frédéric Stauffer
Almmustuhtton 2016Artigo -
2
Discovery of Potent, Selective, and Structurally Novel Dot1L Inhibitors by a Fragment Linking Approach Dahkki Henrik Möbitz, Rainer Machauer, Philipp Holzer, Andrea Vaupel, Frédéric Stauffer, Christian Ragot, Giorgio Caravatti, Clemens Scheufler, César Fernández Fernández, Ulrich Hommel, Ralph Tiedt, Kim S. Beyer, Chao Chen, Hugh Zhu, Christoph Gaul
Almmustuhtton 2017Artigo -
3
Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach Dahkki Chao Chen, Hugh Zhu, Frédéric Stauffer, Giorgio Caravatti, Susanne Vollmer, Rainer Machauer, Philipp Holzer, Henrik Möbitz, Clemens Scheufler, Martin Klumpp, Ralph Tiedt, Kim S. Beyer, Keith Calkins, Daniel Guthy, Michael Kiffe, Jeff Zhang, Christoph Gaul
Almmustuhtton 2016Artigo -
4
Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor Dahkki Alexei S. Karpov, Payman Amiri, Cornelia Bellamacina, Marie-Hélène Bellance, Werner Breitenstein, Dylan Daniel, Régis Denay, Doriano Fabbro, César Fernández Fernández, Inga Galuba, Stephanie Guerro-Lagasse, Sascha Gutmann, Linda Hinh, Wolfgang Jahnke, Julia Klopp, Albert Lai, Mika Lindvall, Sylvia Ma, Henrik Möbitz, Sabina Pecchi, Gabriele Rummel, Kevin Shoemaker, Joerg Trappe, Charles F. Voliva, Sandra W. Cowan‐Jacob, Andreas L. Marzinzik
Almmustuhtton 2015Artigo -
5
Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers Dahkki Stéphane Ferretti, Jacques Hamon, Ruben de Kanter, Clemens Scheufler, Rita Andraos-Rey, Stéphanie Barbé, Elisabeth Bechter, Jutta Blank, Vincent Bordas, Ernesta Dammassa, Eric A. Decker, Noemi Di Nanni, Marion Dourdoigne, Elena Gavioli, Marc Hattenberger, Alisa Heuser, Christelle Hemmerlin, Jürgen Hinrichs, Gráinne Kerr, Laurent Laborde, Isabel Jaco, Eloísa Jiménez Núñez, Hans‐Joerg Martus, Cornelia Quadt, Markus Reschke, Vincent Romanet, Fanny Schaeffer, Joseph Schoepfer, Maxime Schrapp, Ross Strang, Hans Voshol, Markus Wartmann, Sarah Welly, Frédéric J. Zécri, Francesco Hofmann, Henrik Möbitz, Marta Cortés-Cros
Almmustuhtton 2024Artigo
Ohcanreaiddut:
Laktáseaddji fáttát
Biology
Computational biology
Chemistry
Drug discovery
Algorithm
Biochemistry
Cancer research
Computer science
Context (archaeology)
Fragment (logic)
Gene
Genetics
Paleontology
Allele
Allosteric regulation
Bioinformatics
Cancer
Cancer cell
DNA
DNA damage
DNA methylation
DNA repair
Enzyme
Epigenetics
Gene expression
Genome instability
Helicase
Histone
Histone methyltransferase
Kinase