检索结果 - Heckl, Dirk

Multiple genetically engineered humanized microenvironments in a single mouse 由 Lee, Jungwoo, Heckl, Dirk, Parekkadan, Biju

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The Regulatory Roles of Long Noncoding RNAs in Acute Myeloid Leukemia 由 Ng, Michelle, Heckl, Dirk, Klusmann, Jan-Henning

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Molecular Mechanisms of the Genetic Predisposition to Acute Megakaryoblastic Leukemia in Infants With Down Syndrome 由 Grimm, Juliane, Heckl, Dirk, Klusmann, Jan-Henning

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Long noncoding RNAs as regulators of pediatric acute myeloid leukemia 由 Neyazi, Sina, Ng, Michelle, Heckl, Dirk, Klusmann, Jan-Henning

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Combining LSD1 and JAK-STAT inhibition targets Down syndrome-associated myeloid leukemia at its core 由 Grimm, Juliane, Bhayadia, Raj, Gack, Lucie, Heckl, Dirk, Klusmann, Jan-Henning

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RNA-Binding Proteins in Acute Leukemias 由 Schuschel, Konstantin, Helwig, Matthias, Hüttelmaier, Stefan, Heckl, Dirk, Klusmann, Jan-Henning, Hoell, Jessica I

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GATA1s exerts developmental stage-specific effects in human hematopoiesis 由 Gialesaki, Sofia, Mahnken, Anna Katharina, Schmid, Lena, Labuhn, Maurice, Bhayadia, Raj, Heckl, Dirk, Klusmann, Jan-Henning

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Ectopic expression ofHOXC6 blocks myeloid differentiation and predisposes to malignant transformation 由 Wurm, Melanie, Kowalski, John, Heckl, Dirk, Zhang, Xiao-Bing, Nelson, Veronica, Beard, Brian C., Kiem, Hans-Peter

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Meningioma 1 is indispensable for mixed lineage leukemia-rearranged acute myeloid leukemia 由 Sharma, Amit, Jyotsana, Nidhi, Gabdoulline, Razif, Heckl, Dirk, Kuchenbauer, Florian, Slany, Robert K., Ganser, Arnold, Heuser, Michael

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CRISPR-Cas9-induced t(11;19)/MLL-ENL translocations initiate leukemia in human hematopoietic progenitor cells in vivo 由 Reimer, Jana, Knöß, Sabine, Labuhn, Maurice, Charpentier, Emmanuelle M., Göhring, Gudrun, Schlegelberger, Brigitte, Klusmann, Jan-Henning, Heckl, Dirk

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Gene Therapy of Mpl Deficiency: Challenging Balance Between Leukemia and Pancytopenia 由 Wicke, Daniel C, Meyer, Johann, Buesche, Guntram, Heckl, Dirk, Kreipe, Hans, Li, Zhixiong, Welte, Karl H, Ballmaier, Matthias, Baum, Christopher, Modlich, Ute

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The stem cell–specific long noncoding RNA HOXA10-AS in the pathogenesis of KMT2A-rearranged leukemia 由 Al-Kershi, Sina, Bhayadia, Raj, Ng, Michelle, Verboon, Lonneke, Emmrich, Stephan, Gack, Lucie, Schwarzer, Adrian, Strowig, Till, Heckl, Dirk, Klusmann, Jan-Henning

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Lentiviral Vector Induced Insertional Haploinsufficiency of Ebf1 Causes Murine Leukemia 由 Heckl, Dirk, Schwarzer, Adrian, Haemmerle, Reinhard, Steinemann, Doris, Rudolph, Cornelia, Skawran, Britta, Knoess, Sabine, Krause, Johanna, Li, Zhixiong, Schlegelberger, Brigitte, Baum, Christopher, Modlich, Ute

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Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications 由 Labuhn, Maurice, Adams, Felix F, Ng, Michelle, Knoess, Sabine, Schambach, Axel, Charpentier, Emmanuelle M, Schwarzer, Adrian, Mateo, Juan L, Klusmann, Jan-Henning, Heckl, Dirk

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Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing 由 Heckl, Dirk, Kowalczyk, Monika S., Yudovich, David, Belizaire, Roger, Puram, Rishi V., McConkey, Marie E., Thielke, Anne, Aster, Jon C., Regev, Aviv, Ebert, Benjamin L.

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Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells 由 Shalem, Ophir, Sanjana, Neville E., Hartenian, Ella, Shi, Xi, Scott, David A., Mikkelson, Tarjei, Heckl, Dirk, Ebert, Benjamin L., Root, David E., Doench, John G., Zhang, Feng

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Transient Retrovirus-Based CRISPR/Cas9 All-in-One Particles for Efficient, Targeted Gene Knockout 由 Knopp, Yvonne, Geis, Franziska K., Heckl, Dirk, Horn, Stefan, Neumann, Thomas, Kuehle, Johannes, Meyer, Janine, Fehse, Boris, Baum, Christopher, Morgan, Michael, Meyer, Johann, Schambach, Axel, Galla, Melanie

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Gene correction of HAX1 reversed Kostmann disease phenotype in patient-specific induced pluripotent stem cells 由 Pittermann, Erik, Lachmann, Nico, MacLean, Glenn, Emmrich, Stephan, Ackermann, Mania, Göhring, Gudrun, Schlegelberger, Brigitte, Welte, Karl, Schambach, Axel, Heckl, Dirk, Orkin, Stuart H., Cantz, Tobias, Klusmann, Jan-Henning

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Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS 由 Schneider, Rebekka K., Ademà, Vera, Heckl, Dirk, Järås, Marcus, Mallo, Mar, Lord, Allegra M., Chu, Lisa P., McConkey, Marie E., Kramann, Rafael, Mullally, Ann, Bejar, Rafael, Solé, Francesc, Ebert, Benjamin L.

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Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis 由 Kramann, Rafael, Fleig, Susanne V., Schneider, Rebekka K., Fabian, Steven L., DiRocco, Derek P., Maarouf, Omar, Wongboonsin, Janewit, Ikeda, Yoichiro, Heckl, Dirk, Chang, Steven L., Rennke, Helmut G., Waikar, Sushrut S., Humphreys, Benjamin D.

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