Resultats de la cerca - Heather R. Keys

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  1. 1
    Genome-scale CRISPR screening in a single mouse liver

    Genome-scale CRISPR screening in a single mouse liver per Heather R. Keys, Kristin A. Knouse

    Publicat 2022
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  2. 2
    A unifying model for mTORC1-mediated regulation of mRNA translation

    A unifying model for mTORC1-mediated regulation of mRNA translation per Carson C. Thoreen, Lynne Chantranupong, Heather R. Keys, Timothy C. Wang, Nathanael S. Gray, David M. Sabatini

    Publicat 2012
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  3. 3
    CRISPR screens in physiologic medium reveal conditionally essential genes in human cells

    CRISPR screens in physiologic medium reveal conditionally essential genes in human cells per Nicholas J. Rossiter, Kimberly S. Huggler, Charles H. Adelmann, Heather R. Keys, Ross Soens, David M. Sabatini, Jason R. Cantor

    Publicat 2021
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  4. 4
    Genome-wide CRISPR screen for Zika virus resistance in human neural cells

    Genome-wide CRISPR screen for Zika virus resistance in human neural cells per Yun Li, Julien Muffat, Attya Omer, Heather R. Keys, Tenzin Lungjangwa, Irene Bosch, Mehreen Ali Khan, Maria Virgilio, Lee Gehrke, David M. Sabatini, Rudolf Jaenisch

    Publicat 2019
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  5. 5
    Coupled protein quality control during nonsense-mediated mRNA decay

    Coupled protein quality control during nonsense-mediated mRNA decay per Alison J. Inglis, Alina Guna, Ángel Gálvez-Merchán, Akshaye Pal, Theodore K. Esantsi, Heather R. Keys, Evgeni M. Frenkel, Robert Oania, Jonathan S. Weissman, R.M. Voorhees

    Publicat 2023
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  6. 6
    Histidine catabolism is a major determinant of methotrexate sensitivity

    Histidine catabolism is a major determinant of methotrexate sensitivity per Naama Kanarek, Heather R. Keys, Jason R. Cantor, Caroline A. Lewis, Sze Ham Chan, Tenzin Kunchok, Monther Abu-Remaileh, Elizaveta Freinkman, Lawrence D. Schweitzer, David M. Sabatini

    Publicat 2018
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  7. 7
    SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism

    SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism per Nora Kory, Gregory A. Wyant, Gyan Prakash, Jelmi uit de Bos, Francesca Bottanelli, Michael E. Pacold, Sze Ham Chan, Caroline A. Lewis, Timothy C. Wang, Heather R. Keys, Yang Guo, David M. Sabatini

    Publicat 2018
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  8. 8
    Mitochondrial metabolism promotes adaptation to proteotoxic stress

    Mitochondrial metabolism promotes adaptation to proteotoxic stress per Peter Tsvetkov, Alexandre Detappe, Kai Cai, Heather R. Keys, Zarina Brune, Weiwen Ying, Prathapan Thiru, Mairéad Reidy, Guillaume Kugener, Jordan Rossen, Mustafa Kocak, Nora Kory, Aviad Tsherniak, Sandro Santagata, Luke Whitesell, Irene M. Ghobrial, John L. Markley, Susan Lindquist, Todd R. Golub

    Publicat 2019
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  9. 9
    SLC25A38 is required for mitochondrial pyridoxal 5’-phosphate (PLP) accumulation

    SLC25A38 is required for mitochondrial pyridoxal 5’-phosphate (PLP) accumulation per Izabella A. Pena, Ju Shi, Sarah Chang, Jason Yang, Samuel Block, Charles H. Adelmann, Heather R. Keys, Preston Ge, Shveta Bathla, Isabella H. Witham, Grzegorz Sienski, Angus C. Nairn, David M. Sabatini, Caroline A. Lewis, Nora Kory, Matthew G. Vander Heiden, Myriam Heiman

    Publicat 2025
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  10. 10
    Plasticity of ether lipids promotes ferroptosis susceptibility and evasion

    Plasticity of ether lipids promotes ferroptosis susceptibility and evasion per Yilong Zou, Whitney S. Henry, Emily L. Ricq, Emily Graham, Vaishnavi V. Phadnis, Pema Maretich, Sateja Paradkar, Natalie Boehnke, Amy Deik, Ferenc Reinhardt, John K. Eaton, Bryan Ferguson, Wenyu Wang, Joshua Fairman, Heather R. Keys, Vlado Dančík, Clary B. Clish, Paul A. Clemons, Paula T. Hammond, Laurie A. Boyer, Robert A. Weinberg, Stuart L. Schreiber

    Publicat 2020
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  11. 11
    Genome-wide CRISPR screen identifies PRC2 and KMT2D-COMPASS as regulators of distinct EMT trajectories that contribute differentially to metastasis

    Genome-wide CRISPR screen identifies PRC2 and KMT2D-COMPASS as regulators of distinct EMT trajectories that contribute differentially to metastasis per Yun Zhang, Joana Liu Donaher, Sunny Das, Xin Li, Ferenc Reinhardt, Jordan A. Krall, Arthur W. Lambert, Prathapan Thiru, Heather R. Keys, Mehreen Ali Khan, Matan Hofree, Molly M. Wilson, Ozlem Yedier-Bayram, Nathan A. Lack, Tamer T. Önder, Tugba Bagcı-Önder, Michael Tyler, Itay Tirosh, Aviv Regev, Jacqueline A. Lees, Robert A. Weinberg

    Publicat 2022
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