Resultados da busca - Hatton, Charlie

Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma por Conery, Andrew R, Centore, Richard C, Neiss, Adrianne, Keller, Patricia J, Joshi, Shivangi, Spillane, Kerry L, Sandy, Peter, Hatton, Charlie, Pardo, Eneida, Zawadzke, Laura, Bommi-Reddy, Archana, Gascoigne, Karen E, Bryant, Barbara M, Mertz, Jennifer A, Sims, Robert J

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Correction: Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma por Conery, Andrew R, Centore, Richard C, Neiss, Adrianne, Keller, Patricia J, Joshi, Shivangi, Spillane, Kerry L, Sandy, Peter, Hatton, Charlie, Pardo, Eneida, Zawadzke, Laura, Bommi-Reddy, Archana, Gascoigne, Karen E, Bryant, Barbara M, Mertz, Jennifer A, Sims, Robert J

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An Alternative Approach to ChIP-Seq Normalization Enables Detection of Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2 Inhibition por Egan, Brian, Yuan, Chih-Chi, Craske, Madeleine Lisa, Labhart, Paul, Guler, Gulfem D., Arnott, David, Maile, Tobias M., Busby, Jennifer, Henry, Chisato, Kelly, Theresa K., Tindell, Charles A., Jhunjhunwala, Suchit, Zhao, Feng, Hatton, Charlie, Bryant, Barbara M., Classon, Marie, Trojer, Patrick

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High-throughput mutation profiling of CTCL samples reveals KRAS and NRAS mutations sensitizing tumors toward inhibition of the RAS/RAF/MEK signaling cascade por Kießling, Michael K., Oberholzer, Patrick A., Mondal, Chandrani, Karpova, Maria B., Zipser, Marie C., Lin, William M., Girardi, Michael, MacConaill, Laura E., Kehoe, Sarah M., Hatton, Charlie, French, Lars E., Garraway, Levi A., Polier, Gernot, Süss, Dorothee, Klemke, Claus-Detlev, Krammer, Peter H., Gülow, Karsten, Dummer, Reinhard

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Regulation of GLI underlies a role for BET bromodomains in pancreatic cancer growth and the tumor microenvironment por Huang, Yinshi, Nahar, Sabikun, Nakagawa, Akifumi, Fernandez de Barrena, Maite G., Mertz, Jennifer A., Bryant, Barbara M., Adams, Curtis E., Mino-Kenudson, Mari, Von Alt, Kate N., Chang, Kevin, Conery, Andrew R., Hatton, Charlie, Sims, Robert J., Fernandez-Zapico, Martin E., Wang, Xingpeng, Lillemoe, Keith D., Castillo, Carlos Fernández-del, Warshaw, Andrew L., Thayer, Sarah P., Liss, Andrew S.

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Drug-sensitive FGFR2 mutations in endometrial carcinoma por Dutt, Amit, Salvesen, Helga B., Chen, Tzu-Hsiu, Ramos, Alex H., Onofrio, Robert C., Hatton, Charlie, Nicoletti, Richard, Winckler, Wendy, Grewal, Rupinder, Hanna, Megan, Wyhs, Nicolas, Ziaugra, Liuda, Richter, Daniel J., Trovik, Jone, Engelsen, Ingeborg B., Stefansson, Ingunn M., Fennell, Tim, Cibulskis, Kristian, Zody, Michael C., Akslen, Lars A., Gabriel, Stacey, Wong, Kwok-Kin, Sellers, William R., Meyerson, Matthew, Greulich, Heidi

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Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway por Lovejoy, Courtney A., Li, Wendi, Reisenweber, Steven, Thongthip, Supawat, Bruno, Joanne, de Lange, Titia, De, Saurav, Petrini, John H. J., Sung, Patricia A., Jasin, Maria, Rosenbluh, Joseph, Zwang, Yaara, Weir, Barbara A., Hatton, Charlie, Ivanova, Elena, Macconaill, Laura, Hanna, Megan, Hahn, William C., Lue, Neal F., Reddel, Roger R., Jiao, Yuchen, Kinzler, Kenneth, Vogelstein, Bert, Papadopoulos, Nickolas, Meeker, Alan K.

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Prospective Enterprise-Level Molecular Genotyping of a Cohort of Cancer Patients por MacConaill, Laura E., Garcia, Elizabeth, Shivdasani, Priyanka, Ducar, Matthew, Adusumilli, Ravali, Breneiser, Marc, Byrne, Mark, Chung, Lawrence, Conneely, Jodie, Crosby, Lauren, Garraway, Levi A., Gong, Xin, Hahn, William C., Hatton, Charlie, Kantoff, Philip W., Kluk, Michael, Kuo, Frank, Jia, Yonghui, Joshi, Ruchi, Longtine, Janina, Manning, Allison, Palescandolo, Emanuele, Sharaf, Nematullah, Sholl, Lynette, van Hummelen, Paul, Wade, Jacqueline, Wollinson, Bruce M., Zepf, Dimity, Rollins, Barrett J., Lindeman, Neal I.

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Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma por Beroukhim, Rameen, Getz, Gad, Nghiemphu, Leia, Barretina, Jordi, Hsueh, Teli, Linhart, David, Vivanco, Igor, Lee, Jeffrey C., Huang, Julie H., Alexander, Sethu, Du, Jinyan, Kau, Tweeny, Thomas, Roman K., Shah, Kinjal, Soto, Horacio, Perner, Sven, Prensner, John, Debiasi, Ralph M., Demichelis, Francesca, Hatton, Charlie, Rubin, Mark A., Garraway, Levi A., Nelson, Stan F., Liau, Linda, Mischel, Paul S., Cloughesy, Tim F., Meyerson, Matthew, Golub, Todd A., Lander, Eric S., Mellinghoff, Ingo K., Sellers, William R.

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A Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia por Krivtsov, Andrei V., Evans, Kathryn, Gadrey, Jayant Y., Eschle, Benjamin K., Hatton, Charlie, Uckelmann, Hannah J., Ross, Kenneth N., Perner, Florian, Olsen, Sarah N., Pritchard, Tara, McDermott, Lisa, Jones, Connor D., Jing, Duohui, Braytee, Ali, Chacon, Diego, Earley, Eric, McKeever, Brian M., Claremon, David, Gifford, Andrew J., Lee, Heather J., Teicher, Beverly A., Pimanda, John E., Beck, Dominik, Perry, Jennifer A., Smith, Malcolm A., McGeehan, Gerard M., Lock, Richard B., Armstrong, Scott A.

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Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhibition por Ghosh, Srimoyee, Taylor, Alexander, Chin, Melissa, Huang, Hon-Ren, Conery, Andrew R., Mertz, Jennifer A., Salmeron, Andres, Dakle, Pranal J., Mele, Deanna, Cote, Alexandre, Jayaram, Hari, Setser, Jeremy W., Poy, Florence, Hatzivassiliou, Georgia, DeAlmeida-Nagata, Denise, Sandy, Peter, Hatton, Charlie, Romero, F. Anthony, Chiang, Eugene, Reimer, Thornik, Crawford, Terry, Pardo, Eneida, Watson, Venita G., Tsui, Vickie, Cochran, Andrea G., Zawadzke, Laura, Harmange, Jean-Christophe, Audia, James E., Bryant, Barbara M., Cummings, Richard T., Magnuson, Steven R., Grogan, Jane L., Bellon, Steve F., Albrecht, Brian K., Sims, Robert J., Lora, Jose M.

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Subtype-specific genomic alterations define new targets for soft tissue sarcoma therapy por Barretina, Jordi, Taylor, Barry S., Banerji, Shantanu, Ramos, Alexis H., Lagos-Quintana, Mariana, DeCarolis, Penelope L., Shah, Kinjal, Socci, Nicholas D., Weir, Barbara A., Ho, Alan, Chiang, Derek Y., Reva, Boris, Mermel, Craig, Getz, Gad, Antipin, Yevgenyi, Beroukhim, Rameen, Major, John E., Hatton, Charlie, Nicoletti, Richard, Hanna, Megan, Sharpe, Ted, Fennell, Tim, Cibulskis, Kristian, Onofrio, Robert C., Saito, Tsuyoshi, Shukla, Neerav, Lau, Christopher, Nelander, Sven, Silver, Serena, Sougnez, Carrie, Viale, Agnes, Winckler, Wendy, Maki, Robert G., Garraway, Levi A., Lash, Alex, Greulich, Heidi, Root, David, Sellers, William R., Schwartz, Gary K., Antonescu, Cristina R., Lander, Eric S., Varmus, Harold E., Ladanyi, Marc, Sander, Chris, Meyerson, Matthew, Singer, Samuel

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