Rezultati - Harkin, D Paul

Measuring a cell's response to stress: the p53 pathway od Harkin, D Paul, Hall, Peter A

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The complex relationship between BRCA1 and ERα in hereditary breast cancer od Gorski, Julia J., Kennedy, Richard D., Hosey, Alison M., Harkin, D. Paul

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The identification of a novel role for BRCA1 in regulating RNA polymerase I transcription od Johnston, Rebecca, D'Costa, Zenobia, Ray, Swagat, Gorski, Julia, Harkin, D. Paul, Mullan, Paul, Panov, Konstantin I.

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Profiling of the BRCA1 transcriptome through microarray and ChIP-chip analysis od Gorski, Julia J., Savage, Kienan I., Mulligan, Jude M., McDade, Simon S., Blayney, Jaine K., Ge, Zhaoping, Harkin, D. Paul

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Chemoprevention in BRCA1 mutation carriers (CIBRAC): protocol for an open allocation crossover feasibility trial assessing mechanisms of chemoprevention with goserelin and anastroz... od Campbell, Aideen M, Morris, Melanie, Gallagher, Rebecca, Boyd, Ruth, Carson, Hazel, Harkin, D Paul, Wielogorska, Ewa, Elliott, Christopher, Savage, Kienan I, McIntosh, Stuart A

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The RNA processing factors THRAP3 and BCLAF1 promote the DNA damage response through selective mRNA splicing and nuclear export od Vohhodina, Jekaterina, Barros, Eliana M., Savage, Abigail L., Liberante, Fabio G., Manti, Lorenzo, Bankhead, Peter, Cosgrove, Nicola, Madden, Angelina F., Harkin, D. Paul, Savage, Kienan I.

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Molecular classification of non-invasive breast lesions for personalised therapy and chemoprevention od Buckley, Niamh, Boyle, David, McArt, Darragh, Irwin, Gareth, Harkin, D. Paul, Lioe, Tong, McQuaid, Stephen, James, Jacqueline A., Maxwell, Perry, Hamilton, Peter, Mullan, Paul B., Salto-Tellez, Manuel

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Inhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70 od Maheswaran, Shyamala, Englert, Christoph, Zheng, Gang, Lee, Sean Bong, Wong, Jenise, Harkin, D. Paul, Bean, James, Ezzell, Robert, Garvin, A. Julian, McCluskey, Robert T., DeCaprio, James A., Haber, Daniel A.

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BRCA1 is a key regulator of breast differentiation through activation of Notch signalling with implications for anti-endocrine treatment of breast cancers od Buckley, Niamh E., Nic An tSaoir, Caoimhe B., Blayney, Jaine K., Oram, Lisa C., Crawford, Nyree T., D’Costa, Zenobia C., Quinn, Jennifer E., Kennedy, Richard D., Harkin, D. Paul, Mullan, Paul B.

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NF-κB is a Critical Mediator of BRCA1 induced Chemoresistance od Harte, Mary T, Gorski, Julia J, Savage, Kienan I, Purcell, James W, Barros, Eliana M, Burn, Philip M, McFarlane, Cheryl, Mullan, Paul B, Kennedy, Richard D, Perkins, Neil D, Harkin, D Paul

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Generation of a non-small cell lung cancer transcriptome microarray od Tanney, Austin, Oliver, Gavin R, Farztdinov, Vadim, Kennedy, Richard D, Mulligan, Jude M, Fulton, Ciaran E, Farragher, Susan M, Field, John K, Johnston, Patrick G, Harkin, D Paul, Proutski, Vitali, Mulligan, Karl A

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Prior knowledge transfer across transcriptional data sets and technologies using compositional statistics yields new mislabelled ovarian cell line od Blayney, Jaine K., Davison, Timothy, McCabe, Nuala, Walker, Steven, Keating, Karen, Delaney, Thomas, Greenan, Caroline, Williams, Alistair R., McCluggage, W. Glenn, Capes-Davis, Amanda, Harkin, D. Paul, Gourley, Charlie, Kennedy, Richard D.

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Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors od Lappin, Katrina M., Barros, Eliana M., Jhujh, Satpal S., Irwin, Gareth W., McMillan, Hayley, Liberante, Fabio G., Latimer, Cheryl, La Bonte, Melissa J., Mills, Ken I., Harkin, D. Paul, Stewart, Grant S., Savage, Kienan I.

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High EMSY expression defines a BRCA‐like subgroup of high‐grade serous ovarian carcinoma with prolonged survival and hypersensitivity to platinum od Hollis, Robert L., Churchman, Michael, Michie, Caroline O., Rye, Tzyvia, Knight, Laura, McCavigan, Andrena, Perren, Timothy, Williams, Alistair R. W., McCluggage, W. Glenn, Kaplan, Richard S., Jayson, Gordon C., Oza, Amit, Harkin, D. Paul, Herrington, C. Simon, Kennedy, Richard, Gourley, Charlie

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Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability od Savage, Kienan I., Gorski, Julia J., Barros, Eliana M., Irwin, Gareth W., Manti, Lorenzo, Powell, Alexander J., Pellagatti, Andrea, Lukashchuk, Natalia, McCance, Dennis J., McCluggage, W. Glenn, Schettino, Giuseppe, Salto-Tellez, Manuel, Boultwood, Jacqueline, Richard, Derek J., McDade, Simon S., Harkin, D. Paul

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Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer od Parkes, Eileen E., Walker, Steven M., Taggart, Laura E., McCabe, Nuala, Knight, Laura A., Wilkinson, Richard, McCloskey, Karen D., Buckley, Niamh E., Savage, Kienan I., Salto-Tellez, Manuel, McQuaid, Stephen, Harte, Mary T., Mullan, Paul B., Harkin, D. Paul, Kennedy, Richard D.

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Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome od Nichols, Kim E., Harkin, D. Paul, Levitz, Seth, Krainer, Michael, Kolquist, Kathryn Ann, Genovese, Cameo, Bernard, Amy, Ferguson, Martin, Zuo, Lin, Snyder, Eric, Buckler, Alan J., Wise, Carol, Ashley, Jennifer, Lovett, Michael, Valentine, Marcus B., Look, A. Thomas, Gerald, William, Housman, David E., Haber, Daniel A.

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Prognostic and Predictive Biomarkers in Resected Colon Cancer: Current Status and Future Perspectives for Integrating Genomics into Biomarker Discovery od Tejpar, Sabine, Bertagnolli, Monica, Bosman, Fred, Lenz, Heinz-Joseph, Garraway, Levi, Waldman, Frederic, Warren, Robert, Bild, Andrea, Collins-Brennan, Denise, Hahn, Hejin, Harkin, D. Paul, Kennedy, Richard, Ilyas, Mohammad, Morreau, Hans, Proutski, Vitali, Swanton, Charles, Tomlinson, Ian, Delorenzi, Mauro, Fiocca, Roberto, Van Cutsem, Eric, Roth, Arnaud

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PICan: An integromics framework for dynamic cancer biomarker discovery od McArt, Darragh G., Blayney, Jaine K., Boyle, David P., Irwin, Gareth W., Moran, Michael, Hutchinson, Ryan A., Bankhead, Peter, Kieran, Declan, Wang, Yinhai, Dunne, Philip D., Kennedy, Richard D., Mullan, Paul B., Harkin, D. Paul, Catherwood, Mark A., James, Jacqueline A., Salto-Tellez, Manuel, Hamilton, Peter W.

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Association Between Results of a Gene Expression Signature Assay and Recurrence-Free Interval in Patients With Stage II Colon Cancer in Cancer and Leukemia Group B 9581 (Alliance) od Niedzwiecki, Donna, Frankel, Wendy L., Venook, Alan P., Ye, Xing, Friedman, Paula N., Goldberg, Richard M., Mayer, Robert J., Colacchio, Thomas Anthony, Mulligan, Jude Marie, Davison, Timothy S., O’Brien, Eamonn, Kerr, Peter, Johnston, Patrick G., Kennedy, Richard D., Harkin, D. Paul, Schilsky, Richard L., Bertagnolli, Monica M., Warren, Robert S., Innocenti, Federico

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