Torthaí cuardaigh - Harkin, D Paul

Measuring a cell's response to stress: the p53 pathway de réir Harkin, D Paul, Hall, Peter A

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The complex relationship between BRCA1 and ERα in hereditary breast cancer de réir Gorski, Julia J., Kennedy, Richard D., Hosey, Alison M., Harkin, D. Paul

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The identification of a novel role for BRCA1 in regulating RNA polymerase I transcription de réir Johnston, Rebecca, D'Costa, Zenobia, Ray, Swagat, Gorski, Julia, Harkin, D. Paul, Mullan, Paul, Panov, Konstantin I.

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Profiling of the BRCA1 transcriptome through microarray and ChIP-chip analysis de réir Gorski, Julia J., Savage, Kienan I., Mulligan, Jude M., McDade, Simon S., Blayney, Jaine K., Ge, Zhaoping, Harkin, D. Paul

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Chemoprevention in BRCA1 mutation carriers (CIBRAC): protocol for an open allocation crossover feasibility trial assessing mechanisms of chemoprevention with goserelin and anastroz... de réir Campbell, Aideen M, Morris, Melanie, Gallagher, Rebecca, Boyd, Ruth, Carson, Hazel, Harkin, D Paul, Wielogorska, Ewa, Elliott, Christopher, Savage, Kienan I, McIntosh, Stuart A

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The RNA processing factors THRAP3 and BCLAF1 promote the DNA damage response through selective mRNA splicing and nuclear export de réir Vohhodina, Jekaterina, Barros, Eliana M., Savage, Abigail L., Liberante, Fabio G., Manti, Lorenzo, Bankhead, Peter, Cosgrove, Nicola, Madden, Angelina F., Harkin, D. Paul, Savage, Kienan I.

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Molecular classification of non-invasive breast lesions for personalised therapy and chemoprevention de réir Buckley, Niamh, Boyle, David, McArt, Darragh, Irwin, Gareth, Harkin, D. Paul, Lioe, Tong, McQuaid, Stephen, James, Jacqueline A., Maxwell, Perry, Hamilton, Peter, Mullan, Paul B., Salto-Tellez, Manuel

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Inhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70 de réir Maheswaran, Shyamala, Englert, Christoph, Zheng, Gang, Lee, Sean Bong, Wong, Jenise, Harkin, D. Paul, Bean, James, Ezzell, Robert, Garvin, A. Julian, McCluskey, Robert T., DeCaprio, James A., Haber, Daniel A.

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BRCA1 is a key regulator of breast differentiation through activation of Notch signalling with implications for anti-endocrine treatment of breast cancers de réir Buckley, Niamh E., Nic An tSaoir, Caoimhe B., Blayney, Jaine K., Oram, Lisa C., Crawford, Nyree T., D’Costa, Zenobia C., Quinn, Jennifer E., Kennedy, Richard D., Harkin, D. Paul, Mullan, Paul B.

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NF-κB is a Critical Mediator of BRCA1 induced Chemoresistance de réir Harte, Mary T, Gorski, Julia J, Savage, Kienan I, Purcell, James W, Barros, Eliana M, Burn, Philip M, McFarlane, Cheryl, Mullan, Paul B, Kennedy, Richard D, Perkins, Neil D, Harkin, D Paul

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Generation of a non-small cell lung cancer transcriptome microarray de réir Tanney, Austin, Oliver, Gavin R, Farztdinov, Vadim, Kennedy, Richard D, Mulligan, Jude M, Fulton, Ciaran E, Farragher, Susan M, Field, John K, Johnston, Patrick G, Harkin, D Paul, Proutski, Vitali, Mulligan, Karl A

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Prior knowledge transfer across transcriptional data sets and technologies using compositional statistics yields new mislabelled ovarian cell line de réir Blayney, Jaine K., Davison, Timothy, McCabe, Nuala, Walker, Steven, Keating, Karen, Delaney, Thomas, Greenan, Caroline, Williams, Alistair R., McCluggage, W. Glenn, Capes-Davis, Amanda, Harkin, D. Paul, Gourley, Charlie, Kennedy, Richard D.

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Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors de réir Lappin, Katrina M., Barros, Eliana M., Jhujh, Satpal S., Irwin, Gareth W., McMillan, Hayley, Liberante, Fabio G., Latimer, Cheryl, La Bonte, Melissa J., Mills, Ken I., Harkin, D. Paul, Stewart, Grant S., Savage, Kienan I.

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High EMSY expression defines a BRCA‐like subgroup of high‐grade serous ovarian carcinoma with prolonged survival and hypersensitivity to platinum de réir Hollis, Robert L., Churchman, Michael, Michie, Caroline O., Rye, Tzyvia, Knight, Laura, McCavigan, Andrena, Perren, Timothy, Williams, Alistair R. W., McCluggage, W. Glenn, Kaplan, Richard S., Jayson, Gordon C., Oza, Amit, Harkin, D. Paul, Herrington, C. Simon, Kennedy, Richard, Gourley, Charlie

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Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability de réir Savage, Kienan I., Gorski, Julia J., Barros, Eliana M., Irwin, Gareth W., Manti, Lorenzo, Powell, Alexander J., Pellagatti, Andrea, Lukashchuk, Natalia, McCance, Dennis J., McCluggage, W. Glenn, Schettino, Giuseppe, Salto-Tellez, Manuel, Boultwood, Jacqueline, Richard, Derek J., McDade, Simon S., Harkin, D. Paul

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Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer de réir Parkes, Eileen E., Walker, Steven M., Taggart, Laura E., McCabe, Nuala, Knight, Laura A., Wilkinson, Richard, McCloskey, Karen D., Buckley, Niamh E., Savage, Kienan I., Salto-Tellez, Manuel, McQuaid, Stephen, Harte, Mary T., Mullan, Paul B., Harkin, D. Paul, Kennedy, Richard D.

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Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome de réir Nichols, Kim E., Harkin, D. Paul, Levitz, Seth, Krainer, Michael, Kolquist, Kathryn Ann, Genovese, Cameo, Bernard, Amy, Ferguson, Martin, Zuo, Lin, Snyder, Eric, Buckler, Alan J., Wise, Carol, Ashley, Jennifer, Lovett, Michael, Valentine, Marcus B., Look, A. Thomas, Gerald, William, Housman, David E., Haber, Daniel A.

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Prognostic and Predictive Biomarkers in Resected Colon Cancer: Current Status and Future Perspectives for Integrating Genomics into Biomarker Discovery de réir Tejpar, Sabine, Bertagnolli, Monica, Bosman, Fred, Lenz, Heinz-Joseph, Garraway, Levi, Waldman, Frederic, Warren, Robert, Bild, Andrea, Collins-Brennan, Denise, Hahn, Hejin, Harkin, D. Paul, Kennedy, Richard, Ilyas, Mohammad, Morreau, Hans, Proutski, Vitali, Swanton, Charles, Tomlinson, Ian, Delorenzi, Mauro, Fiocca, Roberto, Van Cutsem, Eric, Roth, Arnaud

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PICan: An integromics framework for dynamic cancer biomarker discovery de réir McArt, Darragh G., Blayney, Jaine K., Boyle, David P., Irwin, Gareth W., Moran, Michael, Hutchinson, Ryan A., Bankhead, Peter, Kieran, Declan, Wang, Yinhai, Dunne, Philip D., Kennedy, Richard D., Mullan, Paul B., Harkin, D. Paul, Catherwood, Mark A., James, Jacqueline A., Salto-Tellez, Manuel, Hamilton, Peter W.

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Association Between Results of a Gene Expression Signature Assay and Recurrence-Free Interval in Patients With Stage II Colon Cancer in Cancer and Leukemia Group B 9581 (Alliance) de réir Niedzwiecki, Donna, Frankel, Wendy L., Venook, Alan P., Ye, Xing, Friedman, Paula N., Goldberg, Richard M., Mayer, Robert J., Colacchio, Thomas Anthony, Mulligan, Jude Marie, Davison, Timothy S., O’Brien, Eamonn, Kerr, Peter, Johnston, Patrick G., Kennedy, Richard D., Harkin, D. Paul, Schilsky, Richard L., Bertagnolli, Monica M., Warren, Robert S., Innocenti, Federico

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