Torthaí cuardaigh - Hans‐Ulrich Klein

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  1. 1
    demuxmix: demultiplexing oligonucleotide-barcoded single-cell RNA sequencing data with regression mixture models

    demuxmix: demultiplexing oligonucleotide-barcoded single-cell RNA sequencing data with regression mixture models de réir Hans‐Ulrich Klein

    Foilsithe / Cruthaithe 2023
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  2. 2
    An evaluation of methods to test predefined genomic regions for differential methylation in bisulfite sequencing data

    An evaluation of methods to test predefined genomic regions for differential methylation in bisulfite sequencing data de réir Hans‐Ulrich Klein, Katja Hebestreit

    Foilsithe / Cruthaithe 2015
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  3. 3
    Detection of significantly differentially methylated regions in targeted bisulfite sequencing data

    Detection of significantly differentially methylated regions in targeted bisulfite sequencing data de réir Katja Hebestreit, Martin Dugas, Hans‐Ulrich Klein

    Foilsithe / Cruthaithe 2013
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  4. 4
    The epigenome in Alzheimer’s disease: current state and approaches for a new path to gene discovery and understanding disease mechanism

    The epigenome in Alzheimer’s disease: current state and approaches for a new path to gene discovery and understanding disease mechanism de réir Hans‐Ulrich Klein, David A. Bennett, Philip L. De Jager

    Foilsithe / Cruthaithe 2016
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  5. 5
    Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data

    Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data de réir Christoph Bartenhagen, Hans‐Ulrich Klein, Christian Rückert, Xiaoyi Jiang, Martin Dugas

    Foilsithe / Cruthaithe 2010
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  6. 6
    Leukemia Gene Atlas – A Public Platform for Integrative Exploration of Genome-Wide Molecular Data

    Leukemia Gene Atlas – A Public Platform for Integrative Exploration of Genome-Wide Molecular Data de réir Katja Hebestreit, Sören Gröttrup, Daniel Emden, Jannis Veerkamp, Christian Rückert, Hans‐Ulrich Klein, Carsten Müller‐Tidow, Martin Dugas

    Foilsithe / Cruthaithe 2012
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  7. 7
    Characterization of mitochondrial DNA quantity and quality in the human aged and Alzheimer’s disease brain

    Characterization of mitochondrial DNA quantity and quality in the human aged and Alzheimer’s disease brain de réir Hans‐Ulrich Klein, Caroline Trumpff, Hyun‐Sik Yang, Annie Lee, Martin Picard, David A. Bennett, Philip L. De Jager

    Foilsithe / Cruthaithe 2021
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  8. 8
    Robustness of Amplicon Deep Sequencing Underlines Its Utility in Clinical Applications

    Robustness of Amplicon Deep Sequencing Underlines Its Utility in Clinical Applications de réir Vera Grossmann, Andreas Roller, Hans‐Ulrich Klein, Sandra Weissmann, Wolfgang Kern, Claudia Haferlach, Martin Dugas, Torsten Haferlach, Susanne Schnittger, Alexander Kohlmann

    Foilsithe / Cruthaithe 2013
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  9. 9
    Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer’s disease

    Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer’s disease de réir Andrew Lim, Hans‐Ulrich Klein, Lei Yu, Lori B. Chibnik, Sanam Ali, Jishu Xu, David A. Bennett, Philip L. De Jager

    Foilsithe / Cruthaithe 2017
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  10. 10
    Cortical Proteins and Individual Differences in Cognitive Resilience in Older Adults

    Cortical Proteins and Individual Differences in Cognitive Resilience in Older Adults de réir Andrea R. Zammit, Lei Yu, Vladislav Petyuk, Julie A. Schneider, Philip L. De Jager, Hans‐Ulrich Klein, David A. Bennett, Aron S. Buchman

    Foilsithe / Cruthaithe 2022
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  11. 11
    Multilineage dysplasia (MLD) in acute myeloid leukemia (AML) correlates with MDS-related cytogenetic abnormalities and a prior history of MDS or MDS/MPN but has no independent prognostic relevance: a comparison of 408 cases classified as “AML not otherwise specified” (AML-NOS) or “AML with myelodysplasia-related changes” (AML-MRC)

    Multilineage dysplasia (MLD) in acute myeloid leukemia (AML) correlates with MDS-related cytogenetic abnormalities and a prior history of MDS or MDS/MPN but has no independent prog... de réir Miriam Miesner, Claudia Haferlach, Ulrike Bacher, Tamara Weiss, Katja Macijewski, Alexander Kohlmann, Hans‐Ulrich Klein, Martin Dugas, Wolfgang Kern, Susanne Schnittger, Torsten Haferlach

    Foilsithe / Cruthaithe 2010
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  12. 12
    Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts

    Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts de réir Weichen Zhou, Kalpita R. Karan, Wenjin Gu, Hans‐Ulrich Klein, Gabriel Sturm, Philip L. De Jager, David A. Bennett, Michio Hirano, Martin Picard, Ryan E. Mills

    Foilsithe / Cruthaithe 2024
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  13. 13
    The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes

    The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes de réir Francine Grodstein, Bernardo Lemos, Lei Yu, Hans‐Ulrich Klein, Artemis Iatrou, Aron S. Buchman, Gemma Shireby, Jonathan Mill, Julie A. Schneider, Philip L. De Jager, David A. Bennett

    Foilsithe / Cruthaithe 2021
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  14. 14
    Brain xQTL map: Integrating the genetic architecture of the human brain transcriptome and epigenome

    Brain xQTL map: Integrating the genetic architecture of the human brain transcriptome and epigenome de réir Bernard Ng, C. Jackson White, Hans‐Ulrich Klein, SK Sieberts, Cristin McCabe, Ellis Patrick, Jie Xu, Lei Yu, Chris Gaiteri, Bennett Da, Sara Mostafavi, De Jager Pl

    Foilsithe / Cruthaithe 2017
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  15. 15
    Multiple myeloma is affected by multiple and heterogeneous somatic mutations in adhesion- and receptor tyrosine kinase signaling molecules

    Multiple myeloma is affected by multiple and heterogeneous somatic mutations in adhesion- and receptor tyrosine kinase signaling molecules de réir Ellen Leich, Susann Weißbach, Hans‐Ulrich Klein, T. Grieb, Jordan Pischimarov, Thorsten Stühmer, Manik Chatterjee, Torsten Steinbrunn, Christian Langer, Martin Eilers, Stefan Knop, Hermann Einsele, Ralf C. Bargou, Andreas Rosenwald

    Foilsithe / Cruthaithe 2013
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  16. 16
    An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome

    An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome de réir Bernard Ng, Charles C. White, Hans‐Ulrich Klein, Solveig K. Sieberts, Cristin McCabe, Ellis Patrick, Jishu Xu, Lei Yu, Chris Gaiteri, David A. Bennett, Sara Mostafavi, Philip L. De Jager

    Foilsithe / Cruthaithe 2017
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  17. 17
    Local genetic covariance analysis with lipid traits identifies novel loci for early-onset Alzheimer’s Disease

    Local genetic covariance analysis with lipid traits identifies novel loci for early-onset Alzheimer’s Disease de réir Nicholas R. Ray, Joseph Bradley, Elanur Yılmaz, Çağhan Kızıl, Jiji T. Kurup, Eden R. Martin, Hans‐Ulrich Klein, Brian W. Kunkle, David A. Bennett, Philip L. De Jager, Gary W. Beecham, Carlos Cruchaga, Christiane Reitz

    Foilsithe / Cruthaithe 2025
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  18. 18
    DNA Methyltransferase Inhibition Reverses Epigenetically Embedded Phenotypes in Lung Cancer Preferentially Affecting Polycomb Target Genes

    DNA Methyltransferase Inhibition Reverses Epigenetically Embedded Phenotypes in Lung Cancer Preferentially Affecting Polycomb Target Genes de réir Antje Hascher, Ann-Kristin Haase, Katja Hebestreit, Christian Rohde, Hans‐Ulrich Klein, Maria Rius, Dominik Jungen, Anika Witten, Monika Stoll, Isabell Schulze, Seishi Ogawa, Rainer Wiewrodt, Lara Tickenbrock, Wolfgang E. Berdel, Martin Dugas, Nils H. Thoennissen, Carsten Müller‐Tidow

    Foilsithe / Cruthaithe 2013
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  19. 19
    Multilineage dysplasia has no impact on biologic, clinicopathologic, and prognostic features of AML with mutated nucleophosmin (NPM1)

    Multilineage dysplasia has no impact on biologic, clinicopathologic, and prognostic features of AML with mutated nucleophosmin (NPM1) de réir Brunangelo Falini, Katja Macijewski, Tamara Weiss, Ulrike Bacher, Susanne Schnittger, Wolfgang Kern, Alexander Kohlmann, Hans‐Ulrich Klein, Marco Vignetti, Alfonso Piciocchi, Paola Fazi, Maria Paola Martelli, Antonella Vitale, Stefano Pileri, Miriam Miesner, Antonella Santucci, Claudia Haferlach, Franco Mandelli, Torsten Haferlach

    Foilsithe / Cruthaithe 2010
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  20. 20
    Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells

    Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells de réir Elisabeth Bolton-Gillespie, Mirle Schemionek, Hans‐Ulrich Klein, Sylwia Flis, Grażyna Hoser, Thoralf Lange, Margaret Nieborowska-Skorska, Jacqueline Maier, Linda Kerstiens, Mateusz Koptyra, Martin C. Müller, Hardik Modi, Tomasz Stokłosa, Ilona Seferyńska, Ravi Bhatia, Tessa L. Holyoake, Steffen Koschmieder, Tomasz Skórski

    Foilsithe / Cruthaithe 2013
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