检索结果 - Hanessian, Stephen

Application of cyclic phosphonamide reagents in the total synthesis of natural products and biologically active molecules 由 Focken, Thilo, Hanessian, Stephen

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Total synthesis of the cytotoxic cyclodepsipeptide (-)-doliculide: The “ester” effect in acyclic 1,3-induction of deoxypropionates 由 Hanessian, Stephen, Mascitti, Vincent, Giroux, Simon

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Ni-Catalyzed Reductive and Merged Photocatalytic Cross-Coupling Reactions toward sp(3)/sp(2)-Functionalized Isoquinolones: Creating Diversity at C-6 and C-7 to Address Bioactive An... 由 Dumas, Adrien, Garsi, Jean-Baptiste, Poissonnet, Guillaume, Hanessian, Stephen

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Synthetic Strategies toward Natural Products Containing Contiguous Stereogenic Quaternary Carbons 由 Büschleb, Martin, Dorich, Stéphane, Hanessian, Stephen, Tao, Daniel, Schenthal, Kyle B., Overman, Larry E.

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Inhibition of Aminoglycoside-Deactivating Enzymes APH(3′)-IIIa and AAC(6′)-Ii by Amphiphilic Paromomycin O2″-Ether Analogues 由 Szychowski, Janek, Kondo, Jiro, Zahr, Omar, Auclair, Karine, Westhof, Eric, Hanessian, Stephen, Keillor, Jeffrey W.

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Vorinostat-Like Molecules as Structural, Stereochemical, and Pharmacological Tools 由 Hanessian, Stephen, Auzzas, Luciana, Larsson, Andreas, Zhang, Jianbin, Giannini, Giuseppe, Gallo, Grazia, Ciacci, Andrea, Cabri, Walter

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Design, Synthesis, and Antileukemic Activity of Stereochemically Defined Constrained Analogues of FTY720 (Gilenya) 由 Fransson, Rebecca, McCracken, Alison N., Chen, Bin, McMonigle, Ryan J., Edinger, Aimee L., Hanessian, Stephen

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In search of constrained FTY720 and phytosphingosine analogs as dual acting anticancer agents targeting metabolic and epigenetic pathways 由 Garsi, Jean-Baptiste, Sernissi, Lorenzo, Vece, Vito, Hanessian, Stephen, McCracken, Alison N., Simitian, Grigor, Edinger, Aimee L.

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Crystal Structure of a Bioactive Pactamycin Analog Bound to the 30S Ribosomal Subunit() 由 Tourigny, David S., Fernández, Israel S., Kelley, Ann C., Vakiti, Ramkrishna Reddy, Chattopadhyay, Amit Kumar, Dorich, Stéphane, Hanessian, Stephen, Ramakrishnan, V.

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Dynamic Phosphoproteomics Uncovers Signaling Pathways Modulated by Anti-oncogenic Sphingolipid Analogs 由 Kubiniok, Peter, Finicle, Brendan T., Piffaretti, Fanny, McCracken, Alison N., Perryman, Michael, Hanessian, Stephen, Edinger, Aimee L., Thibault, Pierre

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Design, Synthesis, and Optimization of Balanced Dual NK(1)/NK(3) Receptor Antagonists 由 Hanessian, Stephen, Jennequin, Thomas, Boyer, Nicolas, Babonneau, Vincent, Soma, Udaykumar, Mannoury la Cour, Clotilde, Millan, Mark J., De Nanteuil, Guillaume

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Synthetic Sphingolipids with 1,2-Pyridazine Appendages Improve Antiproliferative Activity in Human Cancer Cell Lines 由 Bachollet, Sylvestre P. J. T., Vece, Vito, McCracken, Alison N., Finicle, Brendan T., Selwan, Elizabeth, Ben Romdhane, Nadine, Dahal, Amogha, Ramirez, Cuauhtemoc, Edinger, Aimee L., Hanessian, Stephen

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Azacyclic FTY720 Analogues that Limit Nutrient Transporter Expression but Lack S1P Receptor Activity and Negative Chronotropic Effects Offer a Novel and Effective Strategy to Kill... 由 Chen, Bin, Roy, Saurabh G., McMonigle, Ryan J., Keebaugh, Andrew, McCracken, Alison N., Selwan, Elizabeth, Fransson, Rebecca, Fallegger, Daniel, Huwiler, Andrea, Kleinman, Michael T., Edinger, Aimee L., Hanessian, Stephen

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Design, synthesis and anticancer activity of constrained sphingolipid-phenoxazine/phenothiazine hybrid constructs targeting protein phosphatase 2A 由 Garsi, Jean-Baptiste, Vece, Vito, Sernissi, Lorenzo, Auger-Morin, Catherine, Hanessian, Stephen, McCracken, Alison N., Selwan, Elizabeth, Ramirez, Cuauhtemoc, Dahal, Amogha, Romdhane, Nadine Ben, Finicle, Brendan T., Edinger, Aimee L.

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Drug‐like sphingolipid SH‐BC‐893 opposes ceramide‐induced mitochondrial fission and corrects diet‐induced obesity 由 Jayashankar, Vaishali, Selwan, Elizabeth, Hancock, Sarah E, Verlande, Amandine, Goodson, Maggie O, Eckenstein, Kazumi H, Milinkeviciute, Giedre, Hoover, Brianna M, Chen, Bin, Fleischman, Angela G, Cramer, Karina S, Hanessian, Stephen, Masri, Selma, Turner, Nigel, Edinger, Aimee L

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Targeting NOX2 via p47/phox-p22/phox Inhibition with Novel Triproline Mimetics 由 Garsi, Jean-Baptiste, Komjáti, Balázs, Cullia, Gregorio, Fejes, Imre, Sipos, Melinda, Sipos, Zoltán, Fördős, Eszter, Markacz, Piroska, Balázs, Barbara, Lancelot, Nathalie, Berger, Sylvie, Raimbaud, Eric, Brown, David, Vuillard, Laurent-Michel, Haberkorn, Laure, Cukier, Cyprian, Szlávik, Zoltán, Hanessian, Stephen

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Toward Overcoming Staphylococcus aureus Aminoglycoside Resistance Mechanisms with a Functionally Designed Neomycin Analogue 由 Hanessian, Stephen, Giguère, Alexandre, Grzyb, Justyna, Maianti, Juan Pablo, Saavedra, Oscar M., Aggen, James B., Linsell, Martin S., Goldblum, Adam A., Hildebrandt, Darin J., Kane, Timothy R., Dozzo, Paola, Gliedt, Micah J., Matias, Rowena D., Feeney, Lee Ann, Armstrong, Eliana S.

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Phosphorylation of a constrained azacyclic FTY720 analog enhances anti-leukemic activity without inducing S1P receptor activation 由 McCracken, Alison N., McMonigle, Ryan J., Tessier, Jérémie, Fransson, Rebecca, Perryman, Michael S., Chen, Bin, Keebaugh, Andrew, Selwan, Elizabeth, Barr, Sarah A., Kim, Seong M., Roy, Saurabh G., Liu, Gang, Fallegger, Daniel, Sernissi, Lorenzo, Brandt, Cordelia, Moitessier, Nicolas, Snider, Ashley J., Clare, Simon, Müschen, Markus, Huwiler, Andrea, Kleinman, Michael T., Hanessian, Stephen, Edinger, Aimee L.

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Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways 由 Kim, Seong M., Roy, Saurabh G., Chen, Bin, Nguyen, Tiffany M., McMonigle, Ryan J., McCracken, Alison N., Zhang, Yanling, Kofuji, Satoshi, Hou, Jue, Selwan, Elizabeth, Finicle, Brendan T., Nguyen, Tricia T., Ravi, Archna, Ramirez, Manuel U., Wiher, Tim, Guenther, Garret G., Kono, Mari, Sasaki, Atsuo T., Weisman, Lois S., Potma, Eric O., Tromberg, Bruce J., Edwards, Robert A., Hanessian, Stephen, Edinger, Aimee L.

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