Rezultati - Hamberg, Paul

(Pre-)Clinical Pharmacology and Activity of Pazopanib, a Novel Multikinase Angiogenesis Inhibitor od Hamberg, Paul, Verweij, Jaap, Sleijfer, Stefan

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A prospective phase I multicentre randomized cross-over pharmacokinetic study to determine the effect of food on abiraterone pharmacokinetics od Lubberman, Floor J. E., Benoist, Guillemette E., Gerritsen, Winald, Burger, David M., Mehra, Niven, Hamberg, Paul, van Oort, Inge, van Erp, Nielka P.

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Effect of ketoconazole-mediated CYP3A4 inhibition on clinical pharmacokinetics of panobinostat (LBH589), an orally active histone deacetylase inhibitor od Hamberg, Paul, Woo, Margaret M., Chen, Lin-Chi, Verweij, Jaap, Porro, Maria Grazia, Zhao, Lily, Li, Wenkui, van der Biessen, Diane, Sharma, Sunil, Hengelage, Thomas, de Jonge, Maja

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The effect of everolimus and low-dose cyclophosphamide on immune cell subsets in patients with metastatic renal cell carcinoma: results from a phase I clinical trial od Huijts, Charlotte M., Lougheed, Sinéad M., Bodalal, Zuhir, van Herpen, Carla M., Hamberg, Paul, Tascilar, Metin, Haanen, John B., Verheul, Henk M., de Gruijl, Tanja D., van der Vliet, Hans J.

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11-Ketotestosterone is the predominant active androgen in prostate cancer patients after castration od Snaterse, Gido, van Dessel, Lisanne F., van Riet, Job, Taylor, Angela E., van der Vlugt-Daane, Michelle, Hamberg, Paul, de Wit, Ronald, Visser, Jenny A., Arlt, Wiebke, Lolkema, Martijn P., Hofland, Johannes

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Relationship Between Sunitinib Pharmacokinetics and Administration Time: Preclinical and Clinical Evidence od Kloth, Jacqueline S. L., Binkhorst, Lisette, de Wit, Annelieke S., de Bruijn, Peter, Hamberg, Paul, Lam, Mei H., Burger, Herman, Chaves, Ines, Wiemer, Erik A. C., van der Horst, Gijsbertus T. J., Mathijssen, Ron H. J.

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Prognostic factors in men with metastatic castration-resistant prostate cancer treated with cabazitaxel od Belderbos, Bodine P.S., de Wit, Ronald, Hoop, Esther Oomen-de, Nieuweboer, Annemieke, Hamberg, Paul, van Alphen, Robbert J., Bergman, André, van der Meer, Nelly, Bins, Sander, Mathijssen, Ron H.J., van Soest, Robert J.

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Phase 1 study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell carcinoma od Huijts, Charlotte M., Werter, Inge M., Lougheed, Sinéad M., Goedegebuure, Ruben S., van Herpen, Carla M., Hamberg, Paul, Tascilar, Metin, Haanen, John B., Verheul, Henk M., de Gruijl, Tanja D., van der Vliet, Hans J.

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Prognostic Impact of HER2 and ER Status of Circulating Tumor Cells in Metastatic Breast Cancer Patients with a HER2-Negative Primary Tumor() od Beije, Nick, Onstenk, Wendy, Kraan, Jaco, Sieuwerts, Anieta M., Hamberg, Paul, Dirix, Luc Y., Brouwer, Anja, de Jongh, Felix E., Jager, Agnes, Seynaeve, Caroline M., Van, Ngoc M., Foekens, John A., Martens, John W.M., Sleijfer, Stefan

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Impact of CYP3A4*22 on Pazopanib Pharmacokinetics in Cancer Patients od Bins, Sander, Huitema, Alwin D. R., Laven, Pim, Bouazzaoui, Samira el, Yu, Huixin, van Erp, Nielka, van Herpen, Carla, Hamberg, Paul, Gelderblom, Hans, Steeghs, Neeltje, Sleijfer, Stefan, van Schaik, Ron H. N., Mathijssen, Ron H. J., Koolen, Stijn L. W.

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Effects of prednisone on docetaxel pharmacokinetics in men with metastatic prostate cancer: A randomized drug–drug interaction study od Belderbos, Bodine P.S., Hussaarts, Koen G.A.M., van Harten, Leonie J., Oomen‐de Hoop, Esther, de Bruijn, Peter, Hamberg, Paul, van Alphen, Robbert J., Haberkorn, Brigitte C.M., Lolkema, Martijn P., de Wit, Ronald, van Soest, Robert J., Mathijssen, Ron H.J.

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The impact of a 1‐hour time interval between pazopanib and subsequent intake of gastric acid suppressants on pazopanib exposure od Krens, Stefanie D., Lubberman, Floor J. E., van Egmond, Marthe, Jansman, Frank G. A., Burger, David M., Hamberg, Paul, Vervenne, Walter L., Gelderblom, Hans, van der Graaf, Winette T. A., Desar, Ingrid M. E., van Herpen, Carla M. L., van Erp, Nielka P.

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A prospective observational registry evaluating clinical outcomes of Radium‐223 treatment in a nonstudy population od Badrising, Sushil K., Louhanepessy, Rebecca D., van der Noort, Vincent, Coenen, Jules L.L.M., Hamberg, Paul, Beeker, Aart, Wagenaar, Nils, Lam, Marnix G.E.H., Celik, Filiz, Loosveld, Olaf J.L., Oostdijk, Ad, Zuetenhorst, Hanneke, Haanen, John B., Vegt, Erik, Zwart, Wilbert, Bergman, Andries M.

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Circadian variation in tamoxifen pharmacokinetics in mice and breast cancer patients od Binkhorst, Lisette, Kloth, Jacqueline S. L., de Wit, Annelieke S., de Bruijn, Peter, Lam, Mei H., Chaves, Ines, Burger, Herman, van Alphen, Robbert J., Hamberg, Paul, van Schaik, Ron H. N., Jager, Agnes, Koch, Birgit C. P., Wiemer, Erik A. C., van Gelder, Teun, van der Horst, Gijsbertus T. J., Mathijssen, Ron H. J.

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Estrogen receptor mutations and splice variants determined in liquid biopsies from metastatic breast cancer patients od Beije, Nick, Sieuwerts, Anieta M., Kraan, Jaco, Van, Ngoc M., Onstenk, Wendy, Vitale, Silvia R., van der Vlugt‐Daane, Michelle, Dirix, Luc Y., Brouwer, Anja, Hamberg, Paul, de Jongh, Felix E., Jager, Agnes, Seynaeve, Caroline M., Jansen, Maurice P. H. M., Foekens, John A., Martens, John W. M., Sleijfer, Stefan

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Circulating Tumor Cell Enumeration and Characterization in Metastatic Castration-Resistant Prostate Cancer Patients Treated with Cabazitaxel od de Kruijff, Ingeborg E., Sieuwerts, Anieta M., Onstenk, Wendy, Kraan, Jaco, Smid, Marcel, Van, Mai N., van der Vlugt-Daane, Michelle, Oomen-de Hoop, Esther, Mathijssen, Ron H.J., Lolkema, Martijn P., de Wit, Ronald, Hamberg, Paul, Meulenbeld, Hielke J., Beeker, Aart, Creemers, Geert-Jan, Martens, John W.M., Sleijfer, Stefan

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RNA Biomarkers as a Response Measure for Survival in Patients with Metastatic Castration-Resistant Prostate Cancer od Boerrigter, Emmy, Benoist, Guillemette E., van Oort, Inge M., Verhaegh, Gerald W., de Haan, Anton F. J., van Hooij, Onno, Groen, Levi, Smit, Frank, Oving, Irma M., de Mol, Pieter, Smilde, Tineke J., Somford, Diederik M., Hamberg, Paul, Dezentjé, Vincent O., Mehra, Niven, van Erp, Nielka P., Schalken, Jack A.

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AR splice variants in circulating tumor cells of patients with castration‐resistant prostate cancer: relation with outcome to cabazitaxel od Sieuwerts, Anieta M., Onstenk, Wendy, Kraan, Jaco, Beaufort, Corine M., Van, Mai, De Laere, Bram, Dirix, Luc Y., Hamberg, Paul, Beeker, Aart, Meulenbeld, Hielke J., Creemers, Geert‐Jan, van Weerden, Wytske M., Jenster, Guido W., Nieuweboer, Annemieke J. M., Mathijssen, Ron H. J., de Wit, Ronald, Martens, John W. M., Sleijfer, Stefan

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An 8-gene mRNA expression profile in circulating tumor cells predicts response to aromatase inhibitors in metastatic breast cancer patients od Reijm, Esther A., Sieuwerts, Anieta M., Smid, Marcel, Vries, Joan Bolt-de, Mostert, Bianca, Onstenk, Wendy, Peeters, Dieter, Dirix, Luc Y., Seynaeve, Caroline M., Jager, Agnes, de Jongh, Felix E., Hamberg, Paul, van Galen, Anne, Kraan, Jaco, Jansen, Maurice P. H. M., Gratama, Jan W., Foekens, John A., Martens, John W. M., Berns, Els M. J. J., Sleijfer, Stefan

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The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact od van Dessel, Lisanne F., van Riet, Job, Smits, Minke, Zhu, Yanyun, Hamberg, Paul, van der Heijden, Michiel S., Bergman, Andries M., van Oort, Inge M., de Wit, Ronald, Voest, Emile E., Steeghs, Neeltje, Yamaguchi, Takafumi N., Livingstone, Julie, Boutros, Paul C., Martens, John W. M., Sleijfer, Stefan, Cuppen, Edwin, Zwart, Wilbert, van de Werken, Harmen J. G., Mehra, Niven, Lolkema, Martijn P.

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