Risultati della ricerca - Halazonetis, T D

Emerging common themes in regulation of PIKKs and PI3Ks di Lempiäinen, Harri, Halazonetis, Thanos D

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Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants. di Halazonetis, T D, Kandil, A N

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Determination of the c-MYC DNA-binding site. di Halazonetis, T D, Kandil, A N

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Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stress di Macheret, Morgane, Halazonetis, Thanos D.

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Retinoic acid increases the sensitivity of the rat embryo fibroblast transformation assay. di Halazonetis, T D, Daugherty, C, Leder, P

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PARP inhibitors and IR join forces to strike glioblastoma-initiating cells di Lugli, N, Kamileri, I, Halazonetis, T D

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DNA replication stress as an Achilles' heel of cancer di Da-Rè, Caterina, Halazonetis, Thanos D.

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Evolutionarily conserved regions of the human c-myc protein can be uncoupled from transforming activity. di Sarid, J, Halazonetis, T D, Murphy, W, Leder, P

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The dihedral symmetry of the p53 tetramerization domain mandates a conformational switch upon DNA binding. di Waterman, J L, Shenk, J L, Halazonetis, T D

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Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA. di Halazonetis, T D, Davis, L J, Kandil, A N

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A Model to Investigate Single-Strand DNA Responses in G1 Human Cells via a Telomere-Targeted, Nuclease-Deficient CRISPR-Cas9 System di Crefcoeur, Remco P., Zgheib, Omar, Halazonetis, Thanos D.

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Studies of genomic copy number changes in human cancers reveal signatures of DNA replication stress di Dereli‐Öz, Aygül, Versini, Gwennaelle, Halazonetis, Thanos D.

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An Oligomerized 53BP1 Tudor Domain Suffices for Recognition of DNA Double-Strand Breaks di Zgheib, Omar, Pataky, Kristopher, Brugger, Juergen, Halazonetis, Thanos D.

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TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint di Cescutti, Rachele, Negrini, Simona, Kohzaki, Masaoki, Halazonetis, Thanos D

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Draining the FEN1s for cancer therapy di Rossetti, Giacomo G., Sotiriou, Sotirios K., Halazonetis, Thanos D.

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Change in oligomerization specificity of the p53 tetramerization domain by hydrophobic amino acid substitutions. di Stavridi, E. S., Chehab, N. H., Caruso, L. C., Halazonetis, T. D.

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Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage di Chehab, Nabil H., Malikzay, Asra, Stavridi, Elena S., Halazonetis, Thanos D.

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Identification of an additional negative regulatory region for p53 sequence-specific DNA binding di Müller-Tiemann, Beate F., Halazonetis, Thanos D., Elting, James J.

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Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53 di Chehab, Nabil H., Malikzay, Asra, Appel, Michael, Halazonetis, Thanos D.

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P53 Binding Protein 1 (53bp1) Is an Early Participant in the Cellular Response to DNA Double-Strand Breaks di Schultz, Linda B., Chehab, Nabil H., Malikzay, Asra, Halazonetis, Thanos D.

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