Søgeresultater - Hailing Cheng
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Targeting the phosphoinositide 3-kinase pathway in cancer af Pixu Liu, Hailing Cheng, Thomas M. Roberts, Jean J. Zhao
Udgivet 2009Revisão -
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Inhibition of palmitoyltransferase <scp>ZDHHC12</scp> sensitizes ovarian cancer cells to cisplatin through <scp>ROS</scp>‐mediated mechanisms af Xining Zhang, Xingming Liao, Min Wang, Jiao Liu, Jiaxin Han, Dong Sung An, Tiezheng Zheng, Xuefei Wang, Hailing Cheng, Pixu Liu
Udgivet 2024Artigo -
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An optimized ratiometric fluorescent probe for sensing human UDP-glucuronosyltransferase 1A1 and its biological applications af Xia Lv, Guang‐Bo Ge, Lei Feng, Johanna Troberg, Lianghai Hu, Jie Hou, Hailing Cheng, Ping Wang, Zhaoming Liu, Moshe Finel, Jingnan Cui, Ling Yang
Udgivet 2015Artigo -
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PTEN deficiency sensitizes endometrioid endometrial cancer to compound PARP-PI3K inhibition but not PARP inhibition as monotherapy af Xiaoying Bian, Jing Gao, Fei Luo, Ceng Rui, Tingting Zheng, Dong‐Yu Wang, Y Wang, Thomas M. Roberts, P Liu, Jean J. Zhao, Hailing Cheng
Udgivet 2017Artigo -
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The p110α and p110β isoforms of PI3K play divergent roles in mammary gland development and tumorigenesis af Tamara Utermark, Trisha Rao, Hailing Cheng, Qi Wang, Sang‐Hyun Lee, Zhigang C. Wang, J. Dirk Iglehart, Thomas M. Roberts, William J. Muller, Jean J. Zhao
Udgivet 2012Artigo -
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Mutant <i>PIK3CA</i> accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies af Ariella B. Hanker, Adam D. Pfefferle, Justin M. Balko, María G. Kuba, Christian D. Young, Violeta Sánchez, Cammie R. Sutton, Hailing Cheng, Charles M. Perou, Jean J. Zhao, Rebecca S. Cook, Carlos L. Arteaga
Udgivet 2013Artigo -
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A Genetic Mouse Model of Invasive Endometrial Cancer Driven by Concurrent Loss of Pten and Lkb1 Is Highly Responsive to mTOR Inhibition af Hailing Cheng, Pixu Liu, Fan Zhang, Erbo Xu, Lynn Symonds, Carolynn E. Ohlson, Roderick T. Bronson, Sauveur-Michel Maira, Emmanuelle di Tomaso, Jane Li, Andrea P. Myers, Lewis C. Cantley, Gordon B. Mills, Jean J. Zhao
Udgivet 2013Artigo
Søgeredskaber:
Relaterede emner
Biology
Cancer research
Cell biology
Cancer
Signal transduction
Gene
Genetics
PI3K/AKT/mTOR pathway
Medicine
Internal medicine
Biochemistry
Breast cancer
Chemistry
Protein kinase B
Olaparib
Ovarian cancer
P110α
PARP inhibitor
Poly ADP ribose polymerase
Polymerase
Synthetic lethality
DNA
DNA repair
Downregulation and upregulation
Gene isoform
Gene knockdown
Molecular biology
Mutant
Apoptosis
Endocrinology