Search Results - Hailing Cheng
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Targeting the phosphoinositide 3-kinase pathway in cancer by Pixu Liu, Hailing Cheng, Thomas M. Roberts, Jean J. Zhao
Published 2009Revisão -
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Inhibition of palmitoyltransferase <scp>ZDHHC12</scp> sensitizes ovarian cancer cells to cisplatin through <scp>ROS</scp>‐mediated mechanisms by Xining Zhang, Xingming Liao, Min Wang, Jiao Liu, Jiaxin Han, Dong Sung An, Tiezheng Zheng, Xuefei Wang, Hailing Cheng, Pixu Liu
Published 2024Artigo -
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An optimized ratiometric fluorescent probe for sensing human UDP-glucuronosyltransferase 1A1 and its biological applications by Xia Lv, Guang‐Bo Ge, Lei Feng, Johanna Troberg, Lianghai Hu, Jie Hou, Hailing Cheng, Ping Wang, Zhaoming Liu, Moshe Finel, Jingnan Cui, Ling Yang
Published 2015Artigo -
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PTEN deficiency sensitizes endometrioid endometrial cancer to compound PARP-PI3K inhibition but not PARP inhibition as monotherapy by Xiaoying Bian, Jing Gao, Fei Luo, Ceng Rui, Tingting Zheng, Dong‐Yu Wang, Y Wang, Thomas M. Roberts, P Liu, Jean J. Zhao, Hailing Cheng
Published 2017Artigo -
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The p110α and p110β isoforms of PI3K play divergent roles in mammary gland development and tumorigenesis by Tamara Utermark, Trisha Rao, Hailing Cheng, Qi Wang, Sang‐Hyun Lee, Zhigang C. Wang, J. Dirk Iglehart, Thomas M. Roberts, William J. Muller, Jean J. Zhao
Published 2012Artigo -
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SIK1 Couples LKB1 to p53-Dependent Anoikis and Suppresses Metastasis by Hailing Cheng, Pixu Liu, Zhigang C. Wang, Lihua Zou, Stephanie Santiago, Victoria M. Garbitt, Ole Gjoerup, J. Dirk Iglehart, Alexander Miron, Andrea L. Richardson, William C. Hahn, Jean J. Zhao
Published 2009Artigo -
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Mutant <i>PIK3CA</i> accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies by Ariella B. Hanker, Adam D. Pfefferle, Justin M. Balko, María G. Kuba, Christian D. Young, Violeta Sánchez, Cammie R. Sutton, Hailing Cheng, Charles M. Perou, Jean J. Zhao, Rebecca S. Cook, Carlos L. Arteaga
Published 2013Artigo -
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A Genetic Mouse Model of Invasive Endometrial Cancer Driven by Concurrent Loss of Pten and Lkb1 Is Highly Responsive to mTOR Inhibition by Hailing Cheng, Pixu Liu, Fan Zhang, Erbo Xu, Lynn Symonds, Carolynn E. Ohlson, Roderick T. Bronson, Sauveur-Michel Maira, Emmanuelle di Tomaso, Jane Li, Andrea P. Myers, Lewis C. Cantley, Gordon B. Mills, Jean J. Zhao
Published 2013Artigo
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Biology
Cancer research
Cell biology
Cancer
Signal transduction
Gene
Genetics
PI3K/AKT/mTOR pathway
Medicine
Internal medicine
Biochemistry
Breast cancer
Chemistry
Protein kinase B
Olaparib
Ovarian cancer
P110α
PARP inhibitor
Poly ADP ribose polymerase
Polymerase
Synthetic lethality
DNA
DNA repair
Downregulation and upregulation
Gene isoform
Gene knockdown
Molecular biology
Mutant
Apoptosis
Endocrinology