Ohcanbohtosat - Guillaume M. Hautbergue
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Ribosome-inactivating proteins Dahkki Matthew J. Walsh, Jennifer E. Dodd, Guillaume M. Hautbergue
Almmustuhtton 2013Revisão -
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Structural Basis for the Recognition of Cellular mRNA Export Factor REF by Herpes Viral Proteins HSV-1 ICP27 and HVS ORF57 Dahkki Richard B. Tunnicliffe, Guillaume M. Hautbergue, Priti Kalra, Brian R. Jackson, Adrian Whitehouse, Stuart A. Wilson, Alexander P. Golovanov
Almmustuhtton 2011Artigo -
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Stable transgenic C9orf72 zebrafish model key aspects of the ALS/FTD phenotype and reveal novel pathological features Dahkki M. Shaw, Adrian Higginbottom, Alexander McGown, Lydia M. Castelli, E Goldman James, Guillaume M. Hautbergue, Pamela J. Shaw, Tennore Ramesh
Almmustuhtton 2018Artigo -
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UIF, a New mRNA Export Adaptor that Works Together with REF/ALY, Requires FACT for Recruitment to mRNA Dahkki Guillaume M. Hautbergue, Ming-Lung Hung, Matthew J. Walsh, Ambrosius P. Snijders, Chung-Te Chang, Rachel Jones, Chris P. Ponting, Mark J. Dickman, Stuart A. Wilson
Almmustuhtton 2009Artigo -
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Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy Dahkki Johnathan Cooper‐Knock, Adrian Higginbottom, Matthew J. Stopford, J. Robin Highley, Paul G. Ince, Stephen B. Wharton, Stuart Pickering‐Brown, Janine Kirby, Guillaume M. Hautbergue, Pamela J. Shaw
Almmustuhtton 2015Artigo -
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C9ORF72 GGGGCC Expanded Repeats Produce Splicing Dysregulation which Correlates with Disease Severity in Amyotrophic Lateral Sclerosis Dahkki Johnathan Cooper‐Knock, Joanna J. Bury, Paul R. Heath, Matthew Wyles, Adrian Higginbottom, Catherine Gelsthorpe, J. Robin Highley, Guillaume M. Hautbergue, Magnus Rattray, Janine Kirby, Pamela J. Shaw
Almmustuhtton 2015Artigo -
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Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALS Dahkki André Varcianna, Monika A. Myszczynska, Lydia M. Castelli, Brendan O’Neill, Ye-Seul Kim, Jordan Talbot, Sophie Nyberg, Immanuelle Nyamali, Paul R. Heath, Matthew J. Stopford, Guillaume M. Hautbergue, Laura Ferraiuolo
Almmustuhtton 2019Artigo -
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Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions Dahkki Johnathan Cooper‐Knock, Matthew J. Walsh, Adrian Higginbottom, J. Robin Highley, Mark J. Dickman, Dieter Edbauer, Paul G. Ince, Stephen B. Wharton, Stuart A. Wilson, Janine Kirby, Guillaume M. Hautbergue, Pamela J. Shaw
Almmustuhtton 2014Artigo -
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Arginine methylation and citrullination of splicing factor proline- and glutamine-rich (SFPQ/PSF) regulates its association with mRNA Dahkki Ambrosius P. Snijders, Guillaume M. Hautbergue, Alex Bloom, James C. Williamson, Thomas C. Minshull, Helen L. Phillips, Simeon R. Mihaylov, Douglas T. Gjerde, D. Hornby, Stuart A. Wilson, Paul J. Hurd, Mark J. Dickman
Almmustuhtton 2015Artigo -
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Translating SOD1 Gene Silencing toward the Clinic: A Highly Efficacious, Off-Target-free, and Biomarker-Supported Strategy for fALS Dahkki Tommaso Iannitti, Joseph M. Scarrott, Shibi Likhite, Ian Coldicott, Katherine E. Lewis, Paul R. Heath, Adrian Higginbottom, Monika A. Myszczynska, Marta Milo, Guillaume M. Hautbergue, Kathrin Meyer, Brian K. Kaspar, Laura Ferraiuolo, Pamela J. Shaw, Mimoun Azzouz
Almmustuhtton 2018Artigo -
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Directly converted astrocytes retain the ageing features of the donor fibroblasts and elucidate the astrocytic contribution to human CNS health and disease Dahkki Noemi Gatto, Cleide Dos Santos Souza, Allan C. Shaw, Simon Bell, Monika A. Myszczynska, Samantha K. Powers, Kathrin Meyer, Lydia M. Castelli, Evangelia Karyka, Heather Mortiboys, Mimoun Azzouz, Guillaume M. Hautbergue, Nóra M. Márkus, Pamela J. Shaw, Laura Ferraiuolo
Almmustuhtton 2020Artigo -
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The C9orf72 protein interacts with Rab1a and the <scp>ULK</scp>1 complex to regulate initiation of autophagy Dahkki Christopher P Webster, Emma F. Smith, Claudia S. Bauer, Annekathrin Möller, Guillaume M. Hautbergue, Laura Ferraiuolo, Monika A. Myszczynska, Adrian Higginbottom, Matthew J. Walsh, Alexander J. Whitworth, Brian K. Kaspar, Kathrin Meyer, Pamela J. Shaw, Andrew J. Grierson, Kurt J. De Vos
Almmustuhtton 2016Artigo -
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The master energy homeostasis regulator PGC-1α exhibits an mRNA nuclear export function Dahkki Simeon R. Mihaylov, Lydia M. Castelli, Ya-Hui Lin, Aytaç Gül, Nikita Soni, Christopher Hastings, Helen R. Flynn, Oana Păun, Mark J. Dickman, Ambrosius P. Snijders, Robert Goldstone, Oliver Bandmann, Tatyana A. Shelkovnikova, Heather Mortiboys, Sila K. Ultanir, Guillaume M. Hautbergue
Almmustuhtton 2023Artigo -
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C9orf72 expansion disrupts ATM-mediated chromosomal break repair Dahkki Callum Walker, Saúl Herranz-Martín, Evangelia Karyka, Chunyan Liao, Katherine E. Lewis, Waheba Elsayed, Vera Lukashchuk, Shih‐Chieh Chiang, Swagat Ray, Pádraig J. Mulcahy, Mateusz Jurga, Ioannis Tsagakis, Tommaso Iannitti, Jayanth Chandran, Ian Coldicott, Kurt J. De Vos, Mohamed K. Hassan, Adrian Higginbottom, Pamela J. Shaw, Guillaume M. Hautbergue, Mimoun Azzouz, Sherif F. El‐Khamisy
Almmustuhtton 2017Artigo
Ohcanreaiddut:
Laktáseaddji fáttát
Biology
Gene
Cell biology
Genetics
RNA
Messenger RNA
Medicine
Disease
Biochemistry
Allele
Amyotrophic lateral sclerosis
C9orf72
Pathology
RNA-binding protein
Trinucleotide repeat expansion
Neuroscience
Molecular biology
Neurodegeneration
Chemistry
Computational biology
Astrocyte
Central nervous system
Dementia
Enzyme
Frontotemporal dementia
Internal medicine
Translation (biology)
Alternative splicing
Amino acid
Arginine