Search Results - Guillaume Kugener

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  1. 1
    Extracting Biological Insights from the Project Achilles Genome-Scale CRISPR Screens in Cancer Cell Lines

    Extracting Biological Insights from the Project Achilles Genome-Scale CRISPR Screens in Cancer Cell Lines by Joshua M. Dempster, Jordan Rossen, Mariya Kazachkova, Joshua Pan, Guillaume Kugener, David E. Root, Aviad Tsherniak

    Published 2019
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  2. 2
    A systematic review of virtual reality for the assessment of technical skills in neurosurgery

    A systematic review of virtual reality for the assessment of technical skills in neurosurgery by Justin P. Chan, Dhiraj J. Pangal, Tyler Cardinal, Guillaume Kugener, Yichao Zhu, Arman Roshannai, Nicholas Markarian, Aditya Sinha, Anima Anandkumar, Andrew J. Hung, Gabriel Zada, Daniel A. Donoho

    Published 2021
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  3. 3
    Robotic and robot-assisted skull base neurosurgery: systematic review of current applications and future directions

    Robotic and robot-assisted skull base neurosurgery: systematic review of current applications and future directions by Dhiraj J. Pangal, David J. Coté, Jacob Ruzevick, Benjamin Yarovinsky, Guillaume Kugener, Bozena Wrobel, Elisabeth H. Ference, Mark S. Swanson, Andrew J. Hung, Daniel A. Donoho, Steven L. Giannotta, Gabriel Zada

    Published 2022
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  4. 4
    Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration

    Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration by James M. McFarland, Zandra V. Ho, Guillaume Kugener, Joshua M. Dempster, Phillip G. Montgomery, Jordan Bryan, John M. Krill-Burger, Thomas Green, Francisca Vázquez, Jesse S. Boehm, Todd R. Golub, William C. Hahn, David E. Root, Aviad Tsherniak

    Published 2018
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  5. 5
    Mitochondrial metabolism promotes adaptation to proteotoxic stress

    Mitochondrial metabolism promotes adaptation to proteotoxic stress by Peter Tsvetkov, Alexandre Detappe, Kai Cai, Heather R. Keys, Zarina Brune, Weiwen Ying, Prathapan Thiru, Mairéad Reidy, Guillaume Kugener, Jordan Rossen, Mustafa Kocak, Nora Kory, Aviad Tsherniak, Sandro Santagata, Luke Whitesell, Irene M. Ghobrial, John L. Markley, Susan Lindquist, Todd R. Golub

    Published 2019
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  6. 6
    An <i>In Vivo</i> CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML

    An <i>In Vivo</i> CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML by Shan Lin, Clément Larrue, Nastassja K. Scheidegger, Bo Kyung A. Seong, Neekesh V. Dharia, Miljan Kuljanin, Caroline S. Wechsler, Guillaume Kugener, Amanda L. Robichaud, Amy Saur Conway, Thelma Mashaka, Sarah Mouche, Biniam Adane, Jeremy Ryan, Joseph D. Mancias, Scott T. Younger, Federica Piccioni, Lynn Lee, Mark Wunderlich, Anthony Letai, Jérôme Tamburini, Kimberly Stegmaier

    Published 2021
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  7. 7
    A first-generation pediatric cancer dependency map

    A first-generation pediatric cancer dependency map by Neekesh V. Dharia, Guillaume Kugener, Lillian M. Guenther, Clare F. Malone, Adam D. Durbin, Andrew L. Hong, Thomas P. Howard, Pratiti Bandopadhayay, Caroline S. Wechsler, Iris Fung, Allison Warren, Joshua M. Dempster, John M. Krill-Burger, Brenton R. Paolella, Phoebe Moh, Nishant Jha, Andrew Tang, Philip Montgomery, Jesse S. Boehm, William C. Hahn, Charles W.M. Roberts, James M. McFarland, Aviad Tsherniak, Todd R. Golub, Francisca Vázquez, Kimberly Stegmaier

    Published 2021
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  8. 8
    Genetic and transcriptional evolution alters cancer cell line drug response

    Genetic and transcriptional evolution alters cancer cell line drug response by Uri Ben‐David, Benjamin A. Siranosian, Gavin Ha, Helen Tang, Yaara Oren, Kunihiko Hinohara, Craig A. Strathdee, Joshua M. Dempster, Nicholas Lyons, Robert Burns, Anwesha Nag, Guillaume Kugener, Beth A. Cimini, Peter Tsvetkov, Yosef E. Maruvka, Ryan O’Rourke, Anthony J. Garrity, Andrew A. Tubelli, Pratiti Bandopadhayay, Aviad Tsherniak, Francisca Vázquez, Bang Wong, Chet Birger, Mahmoud Ghandi, Aaron R. Thorner, Joshua A. Bittker, Matthew Meyerson, Gad Getz, Rameen Beroukhim, Todd R. Golub

    Published 2018
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  9. 9
    MDM2 and MDM4 Are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors

    MDM2 and MDM4 Are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors by Thomas P. Howard, Taylor E. Arnoff, Melinda R. Song, Andrew O. Giacomelli, Xiaofeng Wang, Andrew L. Hong, Neekesh V. Dharia, Su Wang, Francisca Vázquez, Minh‐Tam Pham, Ann M. Morgan, Franziska Wachter, Gregory H. Bird, Guillaume Kugener, Elaine M. Oberlick, Matthew G. Rees, Hong L. Tiv, Justin H. Hwang, Katherine H. Walsh, April Cook, John M. Krill-Burger, Aviad Tsherniak, Prafulla C. Gokhale, Peter J. Park, Kimberly Stegmaier, Loren D. Walensky, William C. Hahn, Charles W.M. Roberts

    Published 2019
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  10. 10
    Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q

    Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q by Jasper E. Neggers, Brenton R. Paolella, Adhana Asfaw, Michael Rothberg, Thomas A. Skipper, Annan Yang, Radha L. Kalekar, John M. Krill-Burger, Neekesh V. Dharia, Guillaume Kugener, Jérémie Kalfon, Chen Yuan, Nancy Dumont, Alfredo González, Mai Abdusamad, Yvonne Y. Li, Liam F. Spurr, Westley W. Wu, Adam D. Durbin, Brian M. Wolpin, Federica Piccioni, David E. Root, Jesse S. Boehm, Andrew D. Cherniack, Aviad Tsherniak, Andrew L. Hong, William C. Hahn, Kimberly Stegmaier, Todd R. Golub, Francisca Vázquez, Andrew J. Aguirre

    Published 2020
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  11. 11
    Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition

    Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition by Andrew L. Hong, Yuen‐Yi Tseng, Jeremiah A. Wala, Won‐Jun Kim, Bryan D. Kynnap, Mihir B. Doshi, Guillaume Kugener, Gabriel J. Sandoval, Thomas P. Howard, Ji Li, Xiaoping Yang, Michelle Tillgren, Mahmhoud Ghandi, Abeer Sayeed, Rebecca Deasy, Abigail Ward, Brian McSteen, Katherine Labella, Paula Keskula, Adam Tracy, Cora Connor, Catherine Clinton, Alanna J. Church, Brian D. Crompton, Katherine A. Janeway, Barbara Van Hare, David Sandak, Ole Gjoerup, Pratiti Bandopadhayay, Paul A. Clemons, Stuart L. Schreiber, David E. Root, Prafulla C. Gokhale, Susan Chi, Elizabeth A. Mullen, Charles W.M. Roberts, Cigall Kadoch, Rameen Beroukhim, Keith L. Ligon, Jesse S. Boehm, William C. Hahn

    Published 2019
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  12. 12
    BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma

    BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma by Eshini Panditharatna, Joana G. Marques, Tingjian Wang, Maria Trissal, Ilon Liu, Li Jiang, Alexander Beck, Andrew Groves, Neekesh V. Dharia, Deyao Li, Samantha E. Hoffman, Guillaume Kugener, McKenzie Shaw, Hafsa M. Mire, Olivia A. Hack, Joshua M. Dempster, Caleb A. Lareau, Lingling Dai, Logan H. Sigua, Michael A. Quezada, Ann-Catherine J. Stanton, Meghan Wyatt, Zohra Kalani, Amy Goodale, Francisca Vázquez, Federica Piccioni, John G. Doench, David E. Root, Jamie N. Anastas, Kristen L. Jones, Amy Saur Conway, Sylwia A. Stopka, Michael S. Regan, Yu Liang, Hyuk‐Soo Seo, Kijun Song, Puspalata Bashyal, William P. Jerome, Nathan D. Mathewson, Sirano Dhe‐Paganon, Mario L. Suvà, Ángel M. Carcaboso, Cinzia Lavarino, Jaume Mora, Quang‐Dé Nguyen, Keith L. Ligon, Yang Shi, Sameer Agnihotri, Nathalie Y.R. Agar, Kimberly Stegmaier, Charles D. Stiles, Michelle Monje, Todd R. Golub, Jun Qi, Mariella G. Filbin

    Published 2022
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