Suchergebnisse - Guido J.R. Zaman

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  1. 1
    Ligand-induced folding of the guanine-sensing riboswitch is controlled by a combined predetermined–induced fit mechanism

    Ligand-induced folding of the guanine-sensing riboswitch is controlled by a combined predetermined–induced fit mechanism von Otmar M. Ottink, S.M. Rampersad, Marco Tessari, Guido J.R. Zaman, Hans A. Heus, Sybren S. Wijmenga

    Veröffentlicht 2007
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  2. 2
    A guide to picking the most selective kinase inhibitor tool compounds for pharmacological validation of drug targets

    A guide to picking the most selective kinase inhibitor tool compounds for pharmacological validation of drug targets von Joost C.M. Uitdehaag, Folkert Verkaar, Husam Alwan, Jos de Man, Rogier C. Buijsman, Guido J.R. Zaman

    Veröffentlicht 2012
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  3. 3
    Membrane Topology and Glycosylation of the Human Multidrug Resistance-associated Protein

    Membrane Topology and Glycosylation of the Human Multidrug Resistance-associated Protein von Éva Bakos, Tamás Hegedűs, Zsolt Holló, Ervin Welker, Gábor Tusnády, Guido J.R. Zaman, Marcel J. Flens, András Váradi, Balázs Sarkadi

    Veröffentlicht 1996
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  4. 4
    Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158

    Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158 von Yvonne Grobben, Joost C.M. Uitdehaag, Nicole Willemsen‐Seegers, Werner W.A. Tabak, Jos de Man, Rogier C. Buijsman, Guido J.R. Zaman

    Veröffentlicht 2019
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  5. 5
    Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.

    Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein. von Guido J.R. Zaman, J. Lankelma, Olaf van Tellingen, Jos H. Beijnen, Henk Dekker, Coen C. Paulusma, Ronald P.J. Oude Elferink, Frank Baas, Piet Borst

    Veröffentlicht 1995
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  6. 6
    Quantitative proteomic and phosphoproteomic comparison of human colon cancer DLD-1 cells differing in ploidy and chromosome stability

    Quantitative proteomic and phosphoproteomic comparison of human colon cancer DLD-1 cells differing in ploidy and chromosome stability von Cristina Viganó, Conrad von Schubert, Erik Ahrné, Alexander Schmidt, Thomas Lorber, Lukas Bubendorf, Judith R.F. de Vetter, Guido J.R. Zaman, Zuzana Štorchová, Erich A. Nigg

    Veröffentlicht 2018
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  7. 7
    TTK Inhibitors as a Targeted Therapy for<i>CTNNB1</i>(<b>β</b>-catenin) Mutant Cancers

    TTK Inhibitors as a Targeted Therapy for<i>CTNNB1</i>(<b>β</b>-catenin) Mutant Cancers von Guido J.R. Zaman, Jeroen A.D.M. de Roos, Marion A.A. Libouban, Martine B.W. Prinsen, Jos de Man, Rogier C. Buijsman, Joost C.M. Uitdehaag

    Veröffentlicht 2017
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  8. 8
    Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells.

    Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells. von Raymond Evers, Guido J.R. Zaman, Liesbeth van Deemter, H W Jansen, Jero Calafat, Lauran C. J. M. Oomen, Ronald P.J. Oude Elferink, Piet Borst, Alfred H. Schinkel

    Veröffentlicht 1996
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  9. 9
    Comparative analysis of drug response and gene profiling of HER2-targeted tyrosine kinase inhibitors

    Comparative analysis of drug response and gene profiling of HER2-targeted tyrosine kinase inhibitors von Neil T. Conlon, Jeffrey J. Kooijman, Suzanne J.C. van Gerwen, Winfried R. Mulder, Guido J.R. Zaman, Irmina Diala, Lisa D. Eli, Alshad S. Lalani, John Crown, Denis M. Collins

    Veröffentlicht 2021
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  10. 10
    Chromosomal instability, tolerance of mitotic errors and multidrug resistance are promoted by tetraploidization in human cells

    Chromosomal instability, tolerance of mitotic errors and multidrug resistance are promoted by tetraploidization in human cells von Anastasia Y Kuznetsova, Katarzyna Seget, Giuliana K Moeller, Mirjam S. de Pagter, Jeroen A.D.M. de Roos, Milena Dürrbaum, Christian Kuffer, Stefan Müller, Guido J.R. Zaman, Wigard P. Kloosterman, Zuzana Štorchová

    Veröffentlicht 2015
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  11. 11
    β-Arrestin Recruitment and G Protein Signaling by the Atypical Human Chemokine Decoy Receptor CCX-CKR

    β-Arrestin Recruitment and G Protein Signaling by the Atypical Human Chemokine Decoy Receptor CCX-CKR von Anne O. Watts, Folkert Verkaar, Miranda M.C. van der Lee, Claudia A.W. Timmerman, Martien Kuijer, Jody van Offenbeek, Lambertus H.C.J. van Lith, Martine J. Smit, Rob Leurs, Guido J.R. Zaman, Henry F. Vischer

    Veröffentlicht 2013
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  12. 12
    MEK and PI3K-AKT inhibitors synergistically block activated IL7 receptor signaling in T-cell acute lymphoblastic leukemia

    MEK and PI3K-AKT inhibitors synergistically block activated IL7 receptor signaling in T-cell acute lymphoblastic leukemia von Kirsten Canté-Barrett, J A P Spijkers-Hagelstein, Jessica G. C. A. M. Buijs-Gladdines, Joost C.M. Uitdehaag, Willem K. Smits, Jordy Van Der Zwet, Rogier C. Buijsman, Guido J.R. Zaman, Rob Pieters, Jules P.P. Meijerink

    Veröffentlicht 2016
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  13. 13
    IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study

    IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study von Yunlei Li, Jessica G. C. A. M. Buijs-Gladdines, Kirsten Canté-Barrett, Andrew Stubbs, Eric Vroegindeweij, Willem K. Smits, Ronald van Marion, Winand N.M. Dinjens, Martin A. Horstmann, Roland P. Kuiper, Rogier C. Buijsman, Guido J.R. Zaman, Peter J. van der Spek, Rob Pieters, Jules P.P. Meijerink

    Veröffentlicht 2016
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  14. 14
    Inhibition of the spindle assembly checkpoint kinase TTK enhances the efficacy of docetaxel in a triple-negative breast cancer model

    Inhibition of the spindle assembly checkpoint kinase TTK enhances the efficacy of docetaxel in a triple-negative breast cancer model von Ana Maia, J. de Man, Ute Boon, Aniek Janssen, Ji‐Ying Song, Manja Omerzu, Jan Gerard Sterrenburg, Martine B.W. Prinsen, Nicole Willemsen‐Seegers, J.A.D.M. De Roos, Antoon M. van Doornmalen, Joost C.M. Uitdehaag, Geert J.P.L. Kops, Jos Jonkers, Rogier C. Buijsman, Guido J.R. Zaman, René H. Medema

    Veröffentlicht 2015
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  15. 15
    Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines

    Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines von Gisele Nishiguchi, Lauren G. Mascibroda, Sarah M. Young, Elizabeth A. Caine, Sherif Abdelhamed, Jeffrey J. Kooijman, Darcie J. Miller, Sourav Das, Kevin M. McGowan, Anand Mayasundari, Zhe Shi, Juan M. Barajas, Ryan Hiltenbrand, Anup Aggarwal, Yunchao Chang, Vibhor Mishra, Shilpa Narina, Melvin E. Thomas, Allister J. Loughran, Ravi C. Kalathur, Kaiwen Yu, Suiping Zhou, Xusheng Wang, Anthony A. High, Junmin Peng, Shondra M. Pruett‐Miller, Danette L. Daniels, Marjeta Urh, Anang A. Shelat, Charles G. Mullighan, Kristin M. Riching, Guido J.R. Zaman, Marcus Fischer, Jeffery M. Klco, Zoran Ranković

    Veröffentlicht 2024
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