Sökresultat - Gruber, Harry

A short discussion about the SARS-CoV-2 mRNA-1273 vaccine av Oronsky, Bryan, Gruber, Harry E., Reiners, Wendy, Reid, Tony R.

Hämta fulltext Hämta fulltext Hämta fulltext

ET-23 THERAPEUTIC EFFICACY OF RETROVIRAL REPLICATING VECTORS IN HUMAN BREAST CANCER CNS METASTASIS MODEL av Inagaki, Akihito, Hiraoka, Kei, Kamijima, Shuichi, Robbins, Joan, Jolly, Douglas, Gruber, Harry, Kasahara, Noriyuki

Hämta fulltext Hämta fulltext

RETROVIRAL REPLICATING VECTORS IN CANCER av Logg, Christopher R., Robbins, Joan M., Jolly, Douglas J., Gruber, Harry E., Kasahara, Noriyuki

Hämta fulltext Hämta fulltext Hämta fulltext

TMIC-42. TOCA 511 AND 5-FC INDUCES T CELL-MEDIATED ANTITUMOR IMMUNITY IN A MOUSE GLIOMA MODEL WHICH IS ENHANCED BY THE ADDITION OF A THERAPEUTIC ANTIBODY AGAINST CTLA-4 AND CORRELA... av Jolly, Douglas, Mitchell, Leah, Yagiz, Kader, Espinoza, Fernando Lopez, Mendoza, Daniel, Munday, Anthony, Gruber, Harry

Hämta fulltext Hämta fulltext

Blockade of Type I Interferon (IFN) Production by Retroviral Replicating Vectors and Reduced Tumor Cell Responses to IFN Likely Contribute To Tumor Selectivity av Lin, Amy H., Burrascano, Cindy, Pettersson, Par L., Ibañez, Carlos E., Gruber, Harry E., Jolly, Douglas J.

Hämta fulltext Hämta fulltext Hämta fulltext

AT-29 INTRAVENOUS ADMINISTRATION OF TOCA 511 IN PATIENTS WITH RECURRENT GLIOBLASTOMA av Kalkanis, Steven, Jolly, Doug J., Pertschuk, Dan, Ostertag, Derek, Robbins, Joan M., Huang, Tiffany T., Gruber, Harry, Mikkelsen, Tom

Hämta fulltext Hämta fulltext

THER-06. THERAPEUTIC EFFICACY OF RRV-MEDIATED PRODRUG ACTIVATOR GENE THERAPY IN CLINICAL TRIALS OF RECURRENT HIGH-GRADE GLIOMA AND IN MURINE ORTHOTOPIC MODELS OF INTRACEREBRAL GLIO... av Richardson, Angela, Collins, Sara, Inagaki, Akihito, Armstrong, Valerie, Robbins, David, Ayad, Nagi, Gruber, Harry, Jolly, Douglas, Cloughesy, Timothy, Kasahara, Noriyuki

Hämta fulltext Hämta fulltext

Toca 511 plus 5-fluorocytosine in combination with lomustine shows chemotoxic and immunotherapeutic activity with no additive toxicity in rodent glioblastoma models av Yagiz, Kader, Huang, Tiffany T., Lopez Espinoza, Fernando, Mendoza, Daniel, Ibañez, Carlos E., Gruber, Harry E., Jolly, Douglas J., Robbins, Joan M.

Hämta fulltext Hämta fulltext Hämta fulltext

CADD-23. PD-L1 CHECKPOINT BLOCKADE USING A SINGLE-CHAIN VARIABLE FRAGMENT TARGETING PD-L1 DELIVERED BY RETROVIRAL REPLICATING VECTOR (TOCA 521) ENHANCES ANTI-TUMOR EFFECT IN CANCER... av Lin, Amy, Yagiz, Kader, Hofacre, Andrew, Munday, Anthony, Espinoza, Fernando Lopez, Mendoza, Daniel, Burrascano, Cynthia, Gruber, Harry, Mitchell, Leah, Jolly, Douglas

Hämta fulltext Hämta fulltext

Retroviral Replicating Vector Delivery of miR-PDL1 Inhibits Immune Checkpoint PDL1 and Enhances Immune Responses In Vitro av Lin, Amy H., Twitty, Christopher G., Burnett, Ryan, Hofacre, Andrew, Mitchell, Leah A., Espinoza, Fernando Lopez, Gruber, Harry E., Jolly, Douglas J.

Hämta fulltext Hämta fulltext Hämta fulltext

Extensive Replication of a Retroviral Replicating Vector Can Expand the A Bulge in the Encephalomyocarditis Virus Internal Ribosome Entry Site and Change Translation Efficiency of... av Lin, Amy H., Liu, Yanzheng, Burrascano, Cynthia, Cunanan, Kathrina, Logg, Christopher R., Robbins, Joan M., Kasahara, Noriyuki, Gruber, Harry, Ibañez, Carlos, Jolly, Douglas J.

Hämta fulltext Hämta fulltext Hämta fulltext

Convection-enhanced delivery improves distribution and efficacy of tumor-selective retroviral replicating vectors (RRV) in a rodent brain tumor model av Yin, Dali, Zhai, Yuying, Gruber, Harry E., Ibanez, Carlos E., Robbins, Joan M., Kells, Adrian P., Kasahara, Noriyuki, Forsayeth, John, Jolly, Douglas J., Bankiewicz, Krystof S.

Hämta fulltext Hämta fulltext Hämta fulltext

Toca 511 gene transfer and treatment with the prodrug, 5-fluorocytosine, promotes durable antitumor immunity in a mouse glioma model av Mitchell, Leah A., Lopez Espinoza, Fernando, Mendoza, Daniel, Kato, Yuki, Inagaki, Akihito, Hiraoka, Kei, Kasahara, Noriyuki, Gruber, Harry E., Jolly, Douglas J., Robbins, Joan M.

Hämta fulltext Hämta fulltext Hämta fulltext

TMOD-15. TOCA 511 & TOCA FC: PRE-CLINICAL PROOF OF CONCEPT IN CNS METASTATIC BREAST CANCER av Inagaki, Akihito, Richardson, Angela M, Collins, Sara A, Hiraoka, Kei, Kamijima, Shuichi, Shorr, Jolene, Gruber, Harry, Jolly, Douglas, Merchan, Jaime, Slingerland, Joyce M, Kasahara, Noriyuki

Hämta fulltext Hämta fulltext

Efficient Therapeutic Protein Expression Using Retroviral Replicating Vector with 2A Peptide in Cancer Models av Hofacre, Andrew, Yagiz, Kader, Mendoza, Daniel, Lopez Espinoza, Fernando, Munday, Anthony W., Burrascano, Cynthia, Singer, Oded, Gruber, Harry E., Jolly, Douglas J., Lin, Amy H.

Hämta fulltext Hämta fulltext Hämta fulltext

SCDT-06. QUANTIFIABLE LEVELS OF THE TRANSGENE, CYTOSINE DEAMINASE, IN TUMOR SAMPLES FOLLOWING INTRAVENOUS DELIVERY OF TOCA 511 IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMA av Walbert, Tobias, Bota, Danilella, Vogelbaum, Michael, Kalkanis, Steven, Liau, Linda, Mikkelsen, Tom, Gruber, Harry, Shorr, Jolene, Rodriguez-Aguirre, Maria, Ostertag, Derek, Mitchell, Leah, Jolly, Doug, Cloughesy, Timothy

Hämta fulltext Hämta fulltext

ATIM-21. INTRAVENOUS DELIVERY OF TOCA 511 IN PATIENTS WITH HIGH GRADE GLIOMA RESULTS IN QUANTIFIABLE EXPRESSION OF CYTOSINE DEAMINASE IN TUMOR TISSUE av Walbert, Tobias, Bota, Daniela, Vogelbaum, Michael, Kalkanis, Steven, Liau, Linda, Mikkelsen, Tom, Gruber, Harry, Shorr, Jolene, Rodriguez-Aquirre, Maria, Ostertag, Derek, Mitchell, Leah, Jolly, Douglas, Cloughesy, Timothy

Hämta fulltext Hämta fulltext

Radio-sensitization of gliomas by intracellular generation of 5-fluorouracil potentiates prodrug activator gene therapy with a retroviral replicating vector av Takahashi, Masamichi, Valdes, Gilmer, Hiraoka, Kei, Inagaki, Akihito, Kamijima, Shuichi, Micewicz, Ewa, Gruber, Harry E., Robbins, Joan M., Jolly, Douglas J., McBride, William H., Iwamoto, Keisuke S., Kasahara, Noriyuki

Hämta fulltext Hämta fulltext Hämta fulltext

A Retroviral Replicating Vector Encoding Cytosine Deaminase and 5-FC Induces Immune Memory in Metastatic Colorectal Cancer Models av Yagiz, Kader, Rodriguez-Aguirre, Maria E., Lopez Espinoza, Fernando, Montellano, Tiffany T., Mendoza, Daniel, Mitchell, Leah A., Ibanez, Carlos E., Kasahara, Noriyuki, Gruber, Harry E., Jolly, Douglas J., Robbins, Joan M.

Hämta fulltext Hämta fulltext Hämta fulltext

MicroRNA 142-3p Attenuates Spread of Replicating Retroviral Vector in Hematopoietic Lineage-Derived Cells While Maintaining an Antiviral Immune Response av Lin, Amy H., Timberlake, Nina, Logg, Christopher R., Liu, Yanzheng, Kamijima, Shuichi, Diago, Oscar, Wong, Kenneth, Gammon, Dawn K., Ostertag, Derek, Hacke, Katrin, Yang, Emily C., Gruber, Harry, Kasahara, Noriyuki, Jolly, Douglas J.

Hämta fulltext Hämta fulltext Hämta fulltext