Ohcanbohtosat - Gruber, Harry

A short discussion about the SARS-CoV-2 mRNA-1273 vaccine Dahkki Oronsky, Bryan, Gruber, Harry E., Reiners, Wendy, Reid, Tony R.

Viečča ollesdeavstta Viečča ollesdeavstta Viečča ollesdeavstta

ET-23 THERAPEUTIC EFFICACY OF RETROVIRAL REPLICATING VECTORS IN HUMAN BREAST CANCER CNS METASTASIS MODEL Dahkki Inagaki, Akihito, Hiraoka, Kei, Kamijima, Shuichi, Robbins, Joan, Jolly, Douglas, Gruber, Harry, Kasahara, Noriyuki

Viečča ollesdeavstta Viečča ollesdeavstta

RETROVIRAL REPLICATING VECTORS IN CANCER Dahkki Logg, Christopher R., Robbins, Joan M., Jolly, Douglas J., Gruber, Harry E., Kasahara, Noriyuki

Viečča ollesdeavstta Viečča ollesdeavstta Viečča ollesdeavstta

TMIC-42. TOCA 511 AND 5-FC INDUCES T CELL-MEDIATED ANTITUMOR IMMUNITY IN A MOUSE GLIOMA MODEL WHICH IS ENHANCED BY THE ADDITION OF A THERAPEUTIC ANTIBODY AGAINST CTLA-4 AND CORRELA... Dahkki Jolly, Douglas, Mitchell, Leah, Yagiz, Kader, Espinoza, Fernando Lopez, Mendoza, Daniel, Munday, Anthony, Gruber, Harry

Viečča ollesdeavstta Viečča ollesdeavstta

Blockade of Type I Interferon (IFN) Production by Retroviral Replicating Vectors and Reduced Tumor Cell Responses to IFN Likely Contribute To Tumor Selectivity Dahkki Lin, Amy H., Burrascano, Cindy, Pettersson, Par L., Ibañez, Carlos E., Gruber, Harry E., Jolly, Douglas J.

Viečča ollesdeavstta Viečča ollesdeavstta Viečča ollesdeavstta

AT-29 INTRAVENOUS ADMINISTRATION OF TOCA 511 IN PATIENTS WITH RECURRENT GLIOBLASTOMA Dahkki Kalkanis, Steven, Jolly, Doug J., Pertschuk, Dan, Ostertag, Derek, Robbins, Joan M., Huang, Tiffany T., Gruber, Harry, Mikkelsen, Tom

Viečča ollesdeavstta Viečča ollesdeavstta

THER-06. THERAPEUTIC EFFICACY OF RRV-MEDIATED PRODRUG ACTIVATOR GENE THERAPY IN CLINICAL TRIALS OF RECURRENT HIGH-GRADE GLIOMA AND IN MURINE ORTHOTOPIC MODELS OF INTRACEREBRAL GLIO... Dahkki Richardson, Angela, Collins, Sara, Inagaki, Akihito, Armstrong, Valerie, Robbins, David, Ayad, Nagi, Gruber, Harry, Jolly, Douglas, Cloughesy, Timothy, Kasahara, Noriyuki

Viečča ollesdeavstta Viečča ollesdeavstta

Toca 511 plus 5-fluorocytosine in combination with lomustine shows chemotoxic and immunotherapeutic activity with no additive toxicity in rodent glioblastoma models Dahkki Yagiz, Kader, Huang, Tiffany T., Lopez Espinoza, Fernando, Mendoza, Daniel, Ibañez, Carlos E., Gruber, Harry E., Jolly, Douglas J., Robbins, Joan M.

Viečča ollesdeavstta Viečča ollesdeavstta Viečča ollesdeavstta

CADD-23. PD-L1 CHECKPOINT BLOCKADE USING A SINGLE-CHAIN VARIABLE FRAGMENT TARGETING PD-L1 DELIVERED BY RETROVIRAL REPLICATING VECTOR (TOCA 521) ENHANCES ANTI-TUMOR EFFECT IN CANCER... Dahkki Lin, Amy, Yagiz, Kader, Hofacre, Andrew, Munday, Anthony, Espinoza, Fernando Lopez, Mendoza, Daniel, Burrascano, Cynthia, Gruber, Harry, Mitchell, Leah, Jolly, Douglas

Viečča ollesdeavstta Viečča ollesdeavstta

Retroviral Replicating Vector Delivery of miR-PDL1 Inhibits Immune Checkpoint PDL1 and Enhances Immune Responses In Vitro Dahkki Lin, Amy H., Twitty, Christopher G., Burnett, Ryan, Hofacre, Andrew, Mitchell, Leah A., Espinoza, Fernando Lopez, Gruber, Harry E., Jolly, Douglas J.

Viečča ollesdeavstta Viečča ollesdeavstta Viečča ollesdeavstta

Extensive Replication of a Retroviral Replicating Vector Can Expand the A Bulge in the Encephalomyocarditis Virus Internal Ribosome Entry Site and Change Translation Efficiency of... Dahkki Lin, Amy H., Liu, Yanzheng, Burrascano, Cynthia, Cunanan, Kathrina, Logg, Christopher R., Robbins, Joan M., Kasahara, Noriyuki, Gruber, Harry, Ibañez, Carlos, Jolly, Douglas J.

Viečča ollesdeavstta Viečča ollesdeavstta Viečča ollesdeavstta

Convection-enhanced delivery improves distribution and efficacy of tumor-selective retroviral replicating vectors (RRV) in a rodent brain tumor model Dahkki Yin, Dali, Zhai, Yuying, Gruber, Harry E., Ibanez, Carlos E., Robbins, Joan M., Kells, Adrian P., Kasahara, Noriyuki, Forsayeth, John, Jolly, Douglas J., Bankiewicz, Krystof S.

Viečča ollesdeavstta Viečča ollesdeavstta Viečča ollesdeavstta

Toca 511 gene transfer and treatment with the prodrug, 5-fluorocytosine, promotes durable antitumor immunity in a mouse glioma model Dahkki Mitchell, Leah A., Lopez Espinoza, Fernando, Mendoza, Daniel, Kato, Yuki, Inagaki, Akihito, Hiraoka, Kei, Kasahara, Noriyuki, Gruber, Harry E., Jolly, Douglas J., Robbins, Joan M.

Viečča ollesdeavstta Viečča ollesdeavstta Viečča ollesdeavstta

TMOD-15. TOCA 511 & TOCA FC: PRE-CLINICAL PROOF OF CONCEPT IN CNS METASTATIC BREAST CANCER Dahkki Inagaki, Akihito, Richardson, Angela M, Collins, Sara A, Hiraoka, Kei, Kamijima, Shuichi, Shorr, Jolene, Gruber, Harry, Jolly, Douglas, Merchan, Jaime, Slingerland, Joyce M, Kasahara, Noriyuki

Viečča ollesdeavstta Viečča ollesdeavstta

Efficient Therapeutic Protein Expression Using Retroviral Replicating Vector with 2A Peptide in Cancer Models Dahkki Hofacre, Andrew, Yagiz, Kader, Mendoza, Daniel, Lopez Espinoza, Fernando, Munday, Anthony W., Burrascano, Cynthia, Singer, Oded, Gruber, Harry E., Jolly, Douglas J., Lin, Amy H.

Viečča ollesdeavstta Viečča ollesdeavstta Viečča ollesdeavstta

SCDT-06. QUANTIFIABLE LEVELS OF THE TRANSGENE, CYTOSINE DEAMINASE, IN TUMOR SAMPLES FOLLOWING INTRAVENOUS DELIVERY OF TOCA 511 IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMA Dahkki Walbert, Tobias, Bota, Danilella, Vogelbaum, Michael, Kalkanis, Steven, Liau, Linda, Mikkelsen, Tom, Gruber, Harry, Shorr, Jolene, Rodriguez-Aguirre, Maria, Ostertag, Derek, Mitchell, Leah, Jolly, Doug, Cloughesy, Timothy

Viečča ollesdeavstta Viečča ollesdeavstta

ATIM-21. INTRAVENOUS DELIVERY OF TOCA 511 IN PATIENTS WITH HIGH GRADE GLIOMA RESULTS IN QUANTIFIABLE EXPRESSION OF CYTOSINE DEAMINASE IN TUMOR TISSUE Dahkki Walbert, Tobias, Bota, Daniela, Vogelbaum, Michael, Kalkanis, Steven, Liau, Linda, Mikkelsen, Tom, Gruber, Harry, Shorr, Jolene, Rodriguez-Aquirre, Maria, Ostertag, Derek, Mitchell, Leah, Jolly, Douglas, Cloughesy, Timothy

Viečča ollesdeavstta Viečča ollesdeavstta

Radio-sensitization of gliomas by intracellular generation of 5-fluorouracil potentiates prodrug activator gene therapy with a retroviral replicating vector Dahkki Takahashi, Masamichi, Valdes, Gilmer, Hiraoka, Kei, Inagaki, Akihito, Kamijima, Shuichi, Micewicz, Ewa, Gruber, Harry E., Robbins, Joan M., Jolly, Douglas J., McBride, William H., Iwamoto, Keisuke S., Kasahara, Noriyuki

Viečča ollesdeavstta Viečča ollesdeavstta Viečča ollesdeavstta

A Retroviral Replicating Vector Encoding Cytosine Deaminase and 5-FC Induces Immune Memory in Metastatic Colorectal Cancer Models Dahkki Yagiz, Kader, Rodriguez-Aguirre, Maria E., Lopez Espinoza, Fernando, Montellano, Tiffany T., Mendoza, Daniel, Mitchell, Leah A., Ibanez, Carlos E., Kasahara, Noriyuki, Gruber, Harry E., Jolly, Douglas J., Robbins, Joan M.

Viečča ollesdeavstta Viečča ollesdeavstta Viečča ollesdeavstta

MicroRNA 142-3p Attenuates Spread of Replicating Retroviral Vector in Hematopoietic Lineage-Derived Cells While Maintaining an Antiviral Immune Response Dahkki Lin, Amy H., Timberlake, Nina, Logg, Christopher R., Liu, Yanzheng, Kamijima, Shuichi, Diago, Oscar, Wong, Kenneth, Gammon, Dawn K., Ostertag, Derek, Hacke, Katrin, Yang, Emily C., Gruber, Harry, Kasahara, Noriyuki, Jolly, Douglas J.

Viečča ollesdeavstta Viečča ollesdeavstta Viečča ollesdeavstta