Ohcanbohtosat - Grimwade, David

Topoisomerase II and leukemia Dahkki Pendleton, MaryJean, Lindsey, R. Hunter, Felix, Carolyn A., Grimwade, David, Osheroff, Neil

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The epigenetic regulator PLZF represses L1 retrotransposition in germ and progenitor cells Dahkki Puszyk, William, Down, Thomas, Grimwade, David, Chomienne, Christine, Oakey, Rebecca J, Solomon, Ellen, Guidez, Fabien

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Attenuated arsenic trioxide plus ATRA therapy for newly diagnosed and relapsed APL: long-term follow-up of the AML17 trial Dahkki Russell, Nigel, Burnett, Alan, Hills, Robert, Betteridge, Sophie, Dennis, Mike, Jovanovic, Jelena, Dillon, Richard, Grimwade, David

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Development of Real-Time Quantitative Polymerase Chain Reaction Assays to Track Treatment Response in Retinoid Resistant Acute Promyelocytic Leukemia Dahkki Jovanovic, Jelena V., Rennie, Kristian, Culligan, Dominic, Peniket, Andrew, Lennard, Anne, Harrison, Justin, Vyas, Paresh, Grimwade, David

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The Cks1/Cks2 axis fine-tunes Mll1 expression and is crucial for MLL-rearranged leukaemia cell viability Dahkki Grey, William, Ivey, Adam, Milne, Thomas A., Haferlach, Torsten, Grimwade, David, Uhlmann, Frank, Voisset, Edwige, Yu, Veronica

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Presenting features and treatment outcome of acute promyelocytic leukemia arising after multiple sclerosis Dahkki Ammatuna, Emanuele, Montesinos, Pau, Hasan, Syed Khizer, Ramadan, Safaa M., Esteve, Jordi, Hubmann, Maximillian, Pagoni, Maria, Grimwade, David, Sanz, Miguel Angel, Lo-Coco, Francesco

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Wilms’ Tumour 1 (WT1) peptide vaccination in patients with acute myeloid leukaemia induces short-lived WT1-specific immune responses Dahkki Uttenthal, Benjamin, Martinez-Davila, Irma, Ivey, Adam, Craddock, Charles, Chen, Frederick, Virchis, Andras, Kottaridis, Panagiotis, Grimwade, David, Khwaja, Asim, Stauss, Hans, Morris, Emma C

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Pml nuclear body disruption cooperates in APL pathogenesis and impairs DNA damage repair pathways in mice Dahkki Voisset, Edwige, Moravcsik, Eva, Stratford, Eva W., Jaye, Amie, Palgrave, Christopher J., Hills, Robert K., Salomoni, Paolo, Kogan, Scott C., Solomon, Ellen, Grimwade, David

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Expression of CD33 is a predictive factor for effect of Gemtuzumab Ozogamicin at different doses in adult acute myeloid leukemia Dahkki Khan, Naeem, Hills, Robert K, Virgo, Paul, Couzens, Stephen, Clark, Nithiya, Gilkes, Amanda, Richardson, Peter, Knapper, Steven, Grimwade, David, Russell, Nigel H, Burnett, Alan K, Freeman, Sylvie D

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Characterisation of Genome-Wide PLZF/RARA Target Genes Dahkki Spicuglia, Salvatore, Vincent-Fabert, Christelle, Benoukraf, Touati, Tibéri, Guillaume, Saurin, Andrew J., Zacarias-Cabeza, Joaquin, Grimwade, David, Mills, Ken, Calmels, Boris, Bertucci, François, Sieweke, Michael, Ferrier, Pierre, Duprez, Estelle

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Comprehensive genomic screens identify a role for PLZF-RARα as a positive regulator of cell proliferation via direct regulation of c-MYC Dahkki Rice, Kim L., Hormaeche, Itsaso, Doulatov, Sergei, Flatow, Jared M., Grimwade, David, Mills, Ken I., Leiva, Magdalena, Ablain, Julien, Ambardekar, Charuta, McConnell, Melanie J., Dick, John E., Licht, Jonathan D.

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Normal Hematopoietic Progenitor Subsets Have Distinct Reactive Oxygen Species, BCL2 and Cell-Cycle Profiles That Are Decoupled from Maturation in Acute Myeloid Leukemia Dahkki Khan, Naeem, Hills, Robert K., Knapper, Steve, Steadman, Lora, Qureshi, Ushna, Rector, Jerrald L., Bradbury, Charlotte, Russell, Nigel H., Vyas, Paresh, Burnett, Alan K., Grimwade, David, Hole, Paul S., Freeman, Sylvie D.

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RARα-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11;17) acute promyelocytic leukemia Dahkki Guidez, Fabien, Parks, Sarah, Wong, Henna, Jovanovic, Jelena V., Mays, Ashley, Gilkes, Amanda F., Mills, Kenneth I., Guillemin, Marie-Claude, Hobbs, Robin M., Pandolfi, Pier Paolo, de Thé, Hugues, Solomon, Ellen, Grimwade, David

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Therapy-related leukaemias with balanced translocations can arise from pre-existing clonal haematopoiesis Dahkki Dillon, Richard, Ahearne, Matthew J., Quek, Lynn, Potter, Nicola, Jovanovic, Jelena, Foot, Nicola, Valganon, Mikel, Jayne, Sandrine, Dennis, Mike, Raj, Kavita, Tauro, Sudhir, Dyer, Martin J. S., Russell, Nigel, Solomon, Ellen, Grimwade, David

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Prognostic value of monitoring a candidate immunophenotypic leukemic stem/progenitor cell population in patients allografted for acute myeloid leukemia Dahkki Bradbury, Charlotte, Houlton, Aimee E, Akiki, Susanna, Gregg, Richard, Rindl, Max, Khan, Josephine, Ward, Janice, Khan, Naeem, Griffiths, Mike, Nagra, Sandeep, Hills, Robert, Burnett, Alan, Russell, Nigel, Vyas, Paresh, Grimwade, David, Craddock, Charles, Freeman, Sylvie D.

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High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia Dahkki Marquis, Miriam, Beaubois, Cyrielle, Lavallée, Vincent-Philippe, Abrahamowicz, Michal, Danieli, Coraline, Lemieux, Sébastien, Ahmad, Imran, Wei, Andrew, Ting, Stephen B., Fleming, Shaun, Schwarer, Anthony, Grimwade, David, Grey, William, Hills, Robert K., Vyas, Paresh, Russell, Nigel, Sauvageau, Guy, Hébert, Josée

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Correction: High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia Dahkki Marquis, Miriam, Beaubois, Cyrielle, Lavallée, Vincent-Philippe, Abrahamowicz, Michal, Danieli, Coraline, Lemieux, Sébastien, Ahmad, Imran, Wei, Andrew, Ting, Stephen B., Fleming, Shaun, Schwarer, Anthony, Grimwade, David, Grey, William, Hills, Robert K., Vyas, Paresh, Russell, Nigel, Sauvageau, Guy, Hébert, Josée

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Evidence for direct involvement of epirubicin in the formation of chromosomal translocations in t(15;17) therapy-related acute promyelocytic leukemia Dahkki Mays, Ashley N., Osheroff, Neil, Xiao, Yuanyuan, Wiemels, Joseph L., Felix, Carolyn A., Byl, Jo Ann W., Saravanamuttu, Kandeepan, Peniket, Andrew, Corser, Robert, Chang, Cherry, Hoyle, Christine, Parker, Anne N., Hasan, Syed K., Lo-Coco, Francesco, Solomon, Ellen, Grimwade, David

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Measurable Residual Disease at Induction Redefines Partial Response in Acute Myeloid Leukemia and Stratifies Outcomes in Patients at Standard Risk Without NPM1 Mutations Dahkki Freeman, Sylvie D., Hills, Robert K., Virgo, Paul, Khan, Naeem, Couzens, Steve, Dillon, Richard, Gilkes, Amanda, Upton, Laura, Nielsen, Ove Juul, Cavenagh, James D., Jones, Gail, Khwaja, Asim, Cahalin, Paul, Thomas, Ian, Grimwade, David, Burnett, Alan K., Russell, Nigel H.

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Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts an... Dahkki Hughes, Timothy, Deininger, Michael, Hochhaus, Andreas, Branford, Susan, Radich, Jerald, Kaeda, Jaspal, Baccarani, Michele, Cortes, Jorge, Cross, Nicholas C. P., Druker, Brian J., Gabert, Jean, Grimwade, David, Hehlmann, Rüdiger, Kamel-Reid, Suzanne, Lipton, Jeffrey H., Longtine, Janina, Martinelli, Giovanni, Saglio, Giuseppe, Soverini, Simona, Stock, Wendy, Goldman, John M.

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