Sökresultat - Greulich, Heidi

Probing the cancer genome av Greulich, Heidi

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The Genomics of Lung Adenocarcinoma: Opportunities for Targeted Therapies av Greulich, Heidi

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Targeting Mutant Fibroblast Growth Factor Receptors in Cancer av Greulich, Heidi, Pollock, Pamela M.

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Activating Mutations in ERBB2 and Their Impact on Diagnostics and Treatment av Herter-Sprie, Grit S., Greulich, Heidi, Wong, Kwok-Kin

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Structures of lung cancer-derived EGFR mutants and inhibitor complexes: Mechanism of activation and insights into differential inhibitor sensitivity av Yun, Cai-Hong, Boggon, Titus J., Li, Yiqun, Woo, Michele S., Greulich, Heidi, Meyerson, Matthew, Eck, Michael J.

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SNP panel identification assay (SPIA): a genetic-based assay for the identification of cell lines av Demichelis, Francesca, Greulich, Heidi, Macoska, Jill A., Beroukhim, Rameen, Sellers, William R., Garraway, Levi, Rubin, Mark A.

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Inhibition of Hsp90 Down-regulates Mutant Epidermal Growth Factor Receptor (EGFR) Expression and Sensitizes EGFR Mutant Tumors to Paclitaxel av Sawai, Ayana, Chandarlapaty, Sarat, Greulich, Heidi, Gonen, Mithat, Ye, Qing, Arteaga, Carlos L., Sellers, William, Rosen, Neal, Solit, David B.

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The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP av Yun, Cai-Hong, Mengwasser, Kristen E., Toms, Angela V., Woo, Michele S., Greulich, Heidi, Wong, Kwok-Kin, Meyerson, Matthew, Eck, Michael J.

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Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma av Imielinski, Marcin, Greulich, Heidi, Kaplan, Bethany, Araujo, Luiz, Amann, Joseph, Horn, Leora, Schiller, Joan, Villalona-Calero, Miguel A., Meyerson, Matthew, Carbone, David P.

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Inhibitor-Sensitive FGFR1 Amplification in Human Non-Small Cell Lung Cancer av Dutt, Amit, Ramos, Alex H., Hammerman, Peter S., Mermel, Craig, Cho, Jeonghee, Sharifnia, Tanaz, Chande, Ajit, Tanaka, Kumiko Elisa, Stransky, Nicolas, Greulich, Heidi, Gray, Nathanael S., Meyerson, Matthew

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Oncogenic Transformation by Inhibitor-Sensitive and -Resistant EGFR Mutants av Greulich, Heidi, Chen, Tzu-Hsiu, Feng, Whei, Jänne, Pasi A, Alvarez, James V, Zappaterra, Mauro, Bulmer, Sara E, Frank, David A, Hahn, William C, Sellers, William R, Meyerson, Matthew

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Loss of the Epigenetic Tumor Suppressor SNF5 Leads to Cancer without Genomic Instability av McKenna, Elizabeth S., Sansam, Courtney G., Cho, Yoon-Jae, Greulich, Heidi, Evans, Julia A., Thom, Christopher S., Moreau, Lisa A., Biegel, Jaclyn A., Pomeroy, Scott L., Roberts, Charles W. M.

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Predicting Relapse in Patients With Medulloblastoma by Integrating Evidence From Clinical and Genomic Features av Tamayo, Pablo, Cho, Yoon-Jae, Tsherniak, Aviad, Greulich, Heidi, Ambrogio, Lauren, Schouten-van Meeteren, Netteke, Zhou, Tianni, Buxton, Allen, Kool, Marcel, Meyerson, Matthew, Pomeroy, Scott L., Mesirov, Jill P.

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Optimization of PDE3A Modulators for SLFN12-Dependent Cancer Cell Killing av Lewis, Timothy A., de Waal, Luc, Wu, Xiaoyun, Youngsaye, Willmen, Wengner, Antje, Kopitz, Charlotte, Lange, Martin, Gradl, Stefan, Ellermann, Manuel, Lienau, Philip, Schreiber, Stuart L., Greulich, Heidi, Meyerson, Matthew

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Cetuximab response of lung cancer-derived EGF receptor mutants is associated with asymmetric dimerization av Cho, Jeonghee, Chen, Liang, Sangji, Naveen, Okabe, Takafumi, Yonesaka, Kimio, Francis, Joshua M., Flavin, Richard J., Johnson, William, Kwon, Jihyun, Yu, Soyoung, Greulich, Heidi E., Johnson, Bruce E., Eck, Michael J., Jänne, Pasi A., Wong, Kwok-Kin, Meyerson, Matthew

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The kinesin KIF1Bβ acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor av Schlisio, Susanne, Kenchappa, Rajappa S., Vredeveld, Liesbeth C.W., George, Rani E., Stewart, Rodney, Greulich, Heidi, Shahriari, Kristina, Nguyen, Nguyen V., Pigny, Pascal, Dahia, Patricia L., Pomeroy, Scott L., Maris, John M., Look, A. Thomas, Meyerson, Matthew, Peeper, Daniel S., Carter, Bruce D., Kaelin, William G.

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An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells av Sheng, Qing, Liu, Xinggang, Fleming, Eleanor, Yuan, Karen, Piao, Huiying, Chen, Jinyun, Moustafa, Zeinab, Thomas, Roman K., Greulich, Heidi, Schinzel, Anna, Zaghlul, Sara, Batt, David, Ettenberg, Seth, Meyerson, Matthew, Schoeberl, Birgit, Kung, Andrew L., Hahn, William C., Drapkin, Ronny, Livingston, David M., Liu, Joyce F.

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Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12 av Wu, Xiaoyun, Schnitzler, Gavin R., Gao, Galen F., Diamond, Brett, Baker, Andrew R., Kaplan, Bethany, Williamson, Kaylyn, Westlake, Lindsay, Lorrey, Selena, Lewis, Timothy A., Garvie, Colin W., Lange, Martin, Hayat, Sikander, Seidel, Henrik, Doench, John, Cherniack, Andrew D., Kopitz, Charlotte, Meyerson, Matthew, Greulich, Heidi

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Correction: Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12. av Wu, Xiaoyun, Schnitzler, Gavin R., Gao, Galen F., Diamond, Brett, Baker, Andrew R., Kaplan, Bethany, Williamson, Kaylyn, Westlake, Lindsay, Lorrey, Selena, Lewis, Timothy A., Garvie, Colin W., Lange, Martin, Hayat, Sikander, Seidel, Henrik, Doench, John, Cherniack, Andrew D., Kopitz, Charlotte, Meyerson, Matthew, Greulich, Heidi

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Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome av Cho, Yoon-Jae, Tsherniak, Aviad, Tamayo, Pablo, Santagata, Sandro, Ligon, Azra, Greulich, Heidi, Berhoukim, Rameen, Amani, Vladimir, Goumnerova, Liliana, Eberhart, Charles G., Lau, Ching C., Olson, James M., Gilbertson, Richard J., Gajjar, Amar, Delattre, Olivier, Kool, Marcel, Ligon, Keith, Meyerson, Matthew, Mesirov, Jill P., Pomeroy, Scott L.

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