Rezultati - Greulich, Heidi

Probing the cancer genome od Greulich, Heidi

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The Genomics of Lung Adenocarcinoma: Opportunities for Targeted Therapies od Greulich, Heidi

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Targeting Mutant Fibroblast Growth Factor Receptors in Cancer od Greulich, Heidi, Pollock, Pamela M.

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Activating Mutations in ERBB2 and Their Impact on Diagnostics and Treatment od Herter-Sprie, Grit S., Greulich, Heidi, Wong, Kwok-Kin

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Structures of lung cancer-derived EGFR mutants and inhibitor complexes: Mechanism of activation and insights into differential inhibitor sensitivity od Yun, Cai-Hong, Boggon, Titus J., Li, Yiqun, Woo, Michele S., Greulich, Heidi, Meyerson, Matthew, Eck, Michael J.

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SNP panel identification assay (SPIA): a genetic-based assay for the identification of cell lines od Demichelis, Francesca, Greulich, Heidi, Macoska, Jill A., Beroukhim, Rameen, Sellers, William R., Garraway, Levi, Rubin, Mark A.

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Inhibition of Hsp90 Down-regulates Mutant Epidermal Growth Factor Receptor (EGFR) Expression and Sensitizes EGFR Mutant Tumors to Paclitaxel od Sawai, Ayana, Chandarlapaty, Sarat, Greulich, Heidi, Gonen, Mithat, Ye, Qing, Arteaga, Carlos L., Sellers, William, Rosen, Neal, Solit, David B.

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The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP od Yun, Cai-Hong, Mengwasser, Kristen E., Toms, Angela V., Woo, Michele S., Greulich, Heidi, Wong, Kwok-Kin, Meyerson, Matthew, Eck, Michael J.

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Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma od Imielinski, Marcin, Greulich, Heidi, Kaplan, Bethany, Araujo, Luiz, Amann, Joseph, Horn, Leora, Schiller, Joan, Villalona-Calero, Miguel A., Meyerson, Matthew, Carbone, David P.

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Inhibitor-Sensitive FGFR1 Amplification in Human Non-Small Cell Lung Cancer od Dutt, Amit, Ramos, Alex H., Hammerman, Peter S., Mermel, Craig, Cho, Jeonghee, Sharifnia, Tanaz, Chande, Ajit, Tanaka, Kumiko Elisa, Stransky, Nicolas, Greulich, Heidi, Gray, Nathanael S., Meyerson, Matthew

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Oncogenic Transformation by Inhibitor-Sensitive and -Resistant EGFR Mutants od Greulich, Heidi, Chen, Tzu-Hsiu, Feng, Whei, Jänne, Pasi A, Alvarez, James V, Zappaterra, Mauro, Bulmer, Sara E, Frank, David A, Hahn, William C, Sellers, William R, Meyerson, Matthew

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Loss of the Epigenetic Tumor Suppressor SNF5 Leads to Cancer without Genomic Instability od McKenna, Elizabeth S., Sansam, Courtney G., Cho, Yoon-Jae, Greulich, Heidi, Evans, Julia A., Thom, Christopher S., Moreau, Lisa A., Biegel, Jaclyn A., Pomeroy, Scott L., Roberts, Charles W. M.

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Predicting Relapse in Patients With Medulloblastoma by Integrating Evidence From Clinical and Genomic Features od Tamayo, Pablo, Cho, Yoon-Jae, Tsherniak, Aviad, Greulich, Heidi, Ambrogio, Lauren, Schouten-van Meeteren, Netteke, Zhou, Tianni, Buxton, Allen, Kool, Marcel, Meyerson, Matthew, Pomeroy, Scott L., Mesirov, Jill P.

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Optimization of PDE3A Modulators for SLFN12-Dependent Cancer Cell Killing od Lewis, Timothy A., de Waal, Luc, Wu, Xiaoyun, Youngsaye, Willmen, Wengner, Antje, Kopitz, Charlotte, Lange, Martin, Gradl, Stefan, Ellermann, Manuel, Lienau, Philip, Schreiber, Stuart L., Greulich, Heidi, Meyerson, Matthew

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Cetuximab response of lung cancer-derived EGF receptor mutants is associated with asymmetric dimerization od Cho, Jeonghee, Chen, Liang, Sangji, Naveen, Okabe, Takafumi, Yonesaka, Kimio, Francis, Joshua M., Flavin, Richard J., Johnson, William, Kwon, Jihyun, Yu, Soyoung, Greulich, Heidi E., Johnson, Bruce E., Eck, Michael J., Jänne, Pasi A., Wong, Kwok-Kin, Meyerson, Matthew

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The kinesin KIF1Bβ acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor od Schlisio, Susanne, Kenchappa, Rajappa S., Vredeveld, Liesbeth C.W., George, Rani E., Stewart, Rodney, Greulich, Heidi, Shahriari, Kristina, Nguyen, Nguyen V., Pigny, Pascal, Dahia, Patricia L., Pomeroy, Scott L., Maris, John M., Look, A. Thomas, Meyerson, Matthew, Peeper, Daniel S., Carter, Bruce D., Kaelin, William G.

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An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells od Sheng, Qing, Liu, Xinggang, Fleming, Eleanor, Yuan, Karen, Piao, Huiying, Chen, Jinyun, Moustafa, Zeinab, Thomas, Roman K., Greulich, Heidi, Schinzel, Anna, Zaghlul, Sara, Batt, David, Ettenberg, Seth, Meyerson, Matthew, Schoeberl, Birgit, Kung, Andrew L., Hahn, William C., Drapkin, Ronny, Livingston, David M., Liu, Joyce F.

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Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12 od Wu, Xiaoyun, Schnitzler, Gavin R., Gao, Galen F., Diamond, Brett, Baker, Andrew R., Kaplan, Bethany, Williamson, Kaylyn, Westlake, Lindsay, Lorrey, Selena, Lewis, Timothy A., Garvie, Colin W., Lange, Martin, Hayat, Sikander, Seidel, Henrik, Doench, John, Cherniack, Andrew D., Kopitz, Charlotte, Meyerson, Matthew, Greulich, Heidi

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Correction: Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12. od Wu, Xiaoyun, Schnitzler, Gavin R., Gao, Galen F., Diamond, Brett, Baker, Andrew R., Kaplan, Bethany, Williamson, Kaylyn, Westlake, Lindsay, Lorrey, Selena, Lewis, Timothy A., Garvie, Colin W., Lange, Martin, Hayat, Sikander, Seidel, Henrik, Doench, John, Cherniack, Andrew D., Kopitz, Charlotte, Meyerson, Matthew, Greulich, Heidi

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Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome od Cho, Yoon-Jae, Tsherniak, Aviad, Tamayo, Pablo, Santagata, Sandro, Ligon, Azra, Greulich, Heidi, Berhoukim, Rameen, Amani, Vladimir, Goumnerova, Liliana, Eberhart, Charles G., Lau, Ching C., Olson, James M., Gilbertson, Richard J., Gajjar, Amar, Delattre, Olivier, Kool, Marcel, Ligon, Keith, Meyerson, Matthew, Mesirov, Jill P., Pomeroy, Scott L.

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