Risultati della ricerca - Greulich, Heidi

Probing the cancer genome di Greulich, Heidi

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The Genomics of Lung Adenocarcinoma: Opportunities for Targeted Therapies di Greulich, Heidi

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Targeting Mutant Fibroblast Growth Factor Receptors in Cancer di Greulich, Heidi, Pollock, Pamela M.

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Activating Mutations in ERBB2 and Their Impact on Diagnostics and Treatment di Herter-Sprie, Grit S., Greulich, Heidi, Wong, Kwok-Kin

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Structures of lung cancer-derived EGFR mutants and inhibitor complexes: Mechanism of activation and insights into differential inhibitor sensitivity di Yun, Cai-Hong, Boggon, Titus J., Li, Yiqun, Woo, Michele S., Greulich, Heidi, Meyerson, Matthew, Eck, Michael J.

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SNP panel identification assay (SPIA): a genetic-based assay for the identification of cell lines di Demichelis, Francesca, Greulich, Heidi, Macoska, Jill A., Beroukhim, Rameen, Sellers, William R., Garraway, Levi, Rubin, Mark A.

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Inhibition of Hsp90 Down-regulates Mutant Epidermal Growth Factor Receptor (EGFR) Expression and Sensitizes EGFR Mutant Tumors to Paclitaxel di Sawai, Ayana, Chandarlapaty, Sarat, Greulich, Heidi, Gonen, Mithat, Ye, Qing, Arteaga, Carlos L., Sellers, William, Rosen, Neal, Solit, David B.

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The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP di Yun, Cai-Hong, Mengwasser, Kristen E., Toms, Angela V., Woo, Michele S., Greulich, Heidi, Wong, Kwok-Kin, Meyerson, Matthew, Eck, Michael J.

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Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma di Imielinski, Marcin, Greulich, Heidi, Kaplan, Bethany, Araujo, Luiz, Amann, Joseph, Horn, Leora, Schiller, Joan, Villalona-Calero, Miguel A., Meyerson, Matthew, Carbone, David P.

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Inhibitor-Sensitive FGFR1 Amplification in Human Non-Small Cell Lung Cancer di Dutt, Amit, Ramos, Alex H., Hammerman, Peter S., Mermel, Craig, Cho, Jeonghee, Sharifnia, Tanaz, Chande, Ajit, Tanaka, Kumiko Elisa, Stransky, Nicolas, Greulich, Heidi, Gray, Nathanael S., Meyerson, Matthew

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Oncogenic Transformation by Inhibitor-Sensitive and -Resistant EGFR Mutants di Greulich, Heidi, Chen, Tzu-Hsiu, Feng, Whei, Jänne, Pasi A, Alvarez, James V, Zappaterra, Mauro, Bulmer, Sara E, Frank, David A, Hahn, William C, Sellers, William R, Meyerson, Matthew

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Loss of the Epigenetic Tumor Suppressor SNF5 Leads to Cancer without Genomic Instability di McKenna, Elizabeth S., Sansam, Courtney G., Cho, Yoon-Jae, Greulich, Heidi, Evans, Julia A., Thom, Christopher S., Moreau, Lisa A., Biegel, Jaclyn A., Pomeroy, Scott L., Roberts, Charles W. M.

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Predicting Relapse in Patients With Medulloblastoma by Integrating Evidence From Clinical and Genomic Features di Tamayo, Pablo, Cho, Yoon-Jae, Tsherniak, Aviad, Greulich, Heidi, Ambrogio, Lauren, Schouten-van Meeteren, Netteke, Zhou, Tianni, Buxton, Allen, Kool, Marcel, Meyerson, Matthew, Pomeroy, Scott L., Mesirov, Jill P.

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Optimization of PDE3A Modulators for SLFN12-Dependent Cancer Cell Killing di Lewis, Timothy A., de Waal, Luc, Wu, Xiaoyun, Youngsaye, Willmen, Wengner, Antje, Kopitz, Charlotte, Lange, Martin, Gradl, Stefan, Ellermann, Manuel, Lienau, Philip, Schreiber, Stuart L., Greulich, Heidi, Meyerson, Matthew

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Cetuximab response of lung cancer-derived EGF receptor mutants is associated with asymmetric dimerization di Cho, Jeonghee, Chen, Liang, Sangji, Naveen, Okabe, Takafumi, Yonesaka, Kimio, Francis, Joshua M., Flavin, Richard J., Johnson, William, Kwon, Jihyun, Yu, Soyoung, Greulich, Heidi E., Johnson, Bruce E., Eck, Michael J., Jänne, Pasi A., Wong, Kwok-Kin, Meyerson, Matthew

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The kinesin KIF1Bβ acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor di Schlisio, Susanne, Kenchappa, Rajappa S., Vredeveld, Liesbeth C.W., George, Rani E., Stewart, Rodney, Greulich, Heidi, Shahriari, Kristina, Nguyen, Nguyen V., Pigny, Pascal, Dahia, Patricia L., Pomeroy, Scott L., Maris, John M., Look, A. Thomas, Meyerson, Matthew, Peeper, Daniel S., Carter, Bruce D., Kaelin, William G.

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An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells di Sheng, Qing, Liu, Xinggang, Fleming, Eleanor, Yuan, Karen, Piao, Huiying, Chen, Jinyun, Moustafa, Zeinab, Thomas, Roman K., Greulich, Heidi, Schinzel, Anna, Zaghlul, Sara, Batt, David, Ettenberg, Seth, Meyerson, Matthew, Schoeberl, Birgit, Kung, Andrew L., Hahn, William C., Drapkin, Ronny, Livingston, David M., Liu, Joyce F.

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Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12 di Wu, Xiaoyun, Schnitzler, Gavin R., Gao, Galen F., Diamond, Brett, Baker, Andrew R., Kaplan, Bethany, Williamson, Kaylyn, Westlake, Lindsay, Lorrey, Selena, Lewis, Timothy A., Garvie, Colin W., Lange, Martin, Hayat, Sikander, Seidel, Henrik, Doench, John, Cherniack, Andrew D., Kopitz, Charlotte, Meyerson, Matthew, Greulich, Heidi

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Correction: Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12. di Wu, Xiaoyun, Schnitzler, Gavin R., Gao, Galen F., Diamond, Brett, Baker, Andrew R., Kaplan, Bethany, Williamson, Kaylyn, Westlake, Lindsay, Lorrey, Selena, Lewis, Timothy A., Garvie, Colin W., Lange, Martin, Hayat, Sikander, Seidel, Henrik, Doench, John, Cherniack, Andrew D., Kopitz, Charlotte, Meyerson, Matthew, Greulich, Heidi

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Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome di Cho, Yoon-Jae, Tsherniak, Aviad, Tamayo, Pablo, Santagata, Sandro, Ligon, Azra, Greulich, Heidi, Berhoukim, Rameen, Amani, Vladimir, Goumnerova, Liliana, Eberhart, Charles G., Lau, Ching C., Olson, James M., Gilbertson, Richard J., Gajjar, Amar, Delattre, Olivier, Kool, Marcel, Ligon, Keith, Meyerson, Matthew, Mesirov, Jill P., Pomeroy, Scott L.

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