Resultados de búsqueda - Gregory M. Findlay

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  1. 1
    Linking genome variants to disease: scalable approaches to test the functional impact of human mutations

    Linking genome variants to disease: scalable approaches to test the functional impact of human mutations por Gregory M. Findlay

    Publicado 2021
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  2. 2
    Genomic Medicine–Progress, Pitfalls, and Promise

    Genomic Medicine–Progress, Pitfalls, and Promise por Jay Shendure, Gregory M. Findlay, Matthew W. Snyder

    Publicado 2019
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  3. 3
    Saturation editing of genomic regions by multiplex homology-directed repair

    Saturation editing of genomic regions by multiplex homology-directed repair por Gregory M. Findlay, Evan A. Boyle, Ronald J. Hause, Jason C. Klein, Jay Shendure

    Publicado 2014
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  4. 4
    High-throughput screening of human genetic variants by pooled prime editing

    High-throughput screening of human genetic variants by pooled prime editing por Michael Herger, Christina M. Kajba, Megan Buckley, Ana Cunha, Molly Strom, Gregory M. Findlay

    Publicado 2025
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  5. 5
    Whole-organism lineage tracing by combinatorial and cumulative genome editing

    Whole-organism lineage tracing by combinatorial and cumulative genome editing por Aaron McKenna, Gregory M. Findlay, James A. Gagnon, Marshall S. Horwitz, Alexander F. Schier, Jay Shendure

    Publicado 2016
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  6. 6
    An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry

    An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry por Sonia Sharma, Ariel Quintana, Gregory M. Findlay, Marcel Mettlen, Beate Baust, Mohit Jain, Roland Nilsson, Anjana Rao, Patrick G. Hogan

    Publicado 2013
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  7. 7
    CRISPR/Cas9-Mediated Scanning for Regulatory Elements Required for HPRT1 Expression via Thousands of Large, Programmed Genomic Deletions

    CRISPR/Cas9-Mediated Scanning for Regulatory Elements Required for HPRT1 Expression via Thousands of Large, Programmed Genomic Deletions por Molly Gasperini, Gregory M. Findlay, Aaron McKenna, Jennifer H. Milbank, Choli Lee, Melissa D. Zhang, Darren A. Cusanovich, Jay Shendure

    Publicado 2017
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  8. 8
    Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex

    Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex por Sonia Sharma, Gregory M. Findlay, Hozefa S. Bandukwala, Shalini Oberdoerffer, Beate Baust, Zhigang Li, Valentina A. Schmidt, Patrick G. Hogan, David B. Sacks, Anjana Rao

    Publicado 2011
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  9. 9
    Accurate classification of BRCA1 variants with saturation genome editing

    Accurate classification of BRCA1 variants with saturation genome editing por Gregory M. Findlay, Riza M. Daza, Beth Martin, Melissa D. Zhang, Anh Leith, Molly Gasperini, Joseph D. Janizek, Xingfan Huang, Lea M. Starita, Jay Shendure

    Publicado 2018
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  10. 10
    spinDrop: a droplet microfluidic platform to maximise single-cell sequencing information content

    spinDrop: a droplet microfluidic platform to maximise single-cell sequencing information content por Joachim De Jonghe, Tomasz S. Kamiński, David B. Morse, Marcin Tabaka, Anna L. Ellermann, Timo N. Kohler, Gianluca Amadei, Charlotte E. Handford, Gregory M. Findlay, Magdalena Zernicka‐Goetz, Sarah A. Teichmann, Florian Hollfelder

    Publicado 2023
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  11. 11
    Membrane dynamics of dividing cells imaged by lattice light-sheet microscopy

    Membrane dynamics of dividing cells imaged by lattice light-sheet microscopy por François Aguet, Srigokul Upadhyayula, Raphaël Gaudin, Yi-ying Chou, Emanuele Cocucci, Kangmin He, Bi‐Chang Chen, Kishore Mosaliganti, Mithun Pasham, Wesley Skillern, Wesley R. Legant, Tsung-Li Liu, Gregory M. Findlay, Eric Marino, Gaudenz Danuser, Sean G. Megason, Eric Betzig, Tomas Kirchhausen

    Publicado 2016
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  12. 12
    Saturation genome editing maps the functional spectrum of pathogenic VHL alleles

    Saturation genome editing maps the functional spectrum of pathogenic VHL alleles por Megan Buckley, Chloé Terwagne, Athina Ganner, Laura Cubitt, Reid A. Brewer, Dong‐Kyu Kim, Christina M. Kajba, N. Forrester, Phoebe Dace, Joachim De Jonghe, Scott T.C. Shepherd, Chelsea Sawyer, Mairead McEwen, Sven Diederichs, Elke Neumann‐Haefelin, Samra Turajlic, Evgueni A. Ivakine, Gregory M. Findlay

    Publicado 2024
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