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1

Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress 著者: Loren D. Walensky, Gregory H. Bird

出版事項 2014

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Revisão

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2

Chemical Synthesis of Hydrocarbon‐Stapled Peptides for Protein Interaction Research and Therapeutic Targeting 著者: Gregory H. Bird, W. Christian Crannell, Loren D. Walensky

出版事項 2011

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Artigo

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3

Chapter 22 Synthesis and Biophysical Characterization of Stabilized α‐Helices of BCL‐2 Domains 著者: Gregory H. Bird, Federico Bernal, Kenneth L. Pitter, Loren D. Walensky

出版事項 2008

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Artigo

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4

BH3-Triggered Structural Reorganization Drives the Activation of Proapoptotic BAX 著者: Evripidis Gavathiotis, Denis E. Reyna, Marguerite L. Davis, Gregory H. Bird, Loren D. Walensky

出版事項 2010

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Artigo

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5

Mechanistic validation of a clinical lead stapled peptide that reactivates p53 by dual HDM2 and HDMX targeting 著者: Franziska Wachter, Ann M. Morgan, Marina Godes, Rida Mourtada, Gregory H. Bird, Loren D. Walensky

出版事項 2016

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Artigo

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6

Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies 著者: Gregory H. Bird, A. Irimia, Gilad Ofek, Peter D. Kwong, Ian A. Wilson, Loren D. Walensky

出版事項 2014

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Artigo

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7

Biophysical determinants for cellular uptake of hydrocarbon-stapled peptide helices 著者: Gregory H. Bird, Emanuele Mazzola, Kwadwo Opoku-Nsiah, Margaret Lammert, Marina Godes, Donna Neuberg, Loren D. Walensky

出版事項 2016

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Artigo

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8

Targeted disruption of the EZH2–EED complex inhibits EZH2-dependent cancer 著者: Woojin Kim, Gregory H. Bird, Tobias Neff, Guoji Guo, Marc A. Kerenyi, Loren D. Walensky, Stuart H. Orkin

出版事項 2013

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Artigo

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9

Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor 著者: Edward P. Harvey, Hyuk‐Soo Seo, Rachel M. Guerra, Gregory H. Bird, Sirano Dhe‐Paganon, Loren D. Walensky

出版事項 2017

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Artigo

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10

Multimodal Interaction with BCL-2 Family Proteins Underlies the Proapoptotic Activity of PUMA BH3 著者: Amanda Edwards, Evripidis Gavathiotis, James L. LaBelle, Craig R. Braun, Kwadwo Opoku-Nsiah, Gregory H. Bird, Loren D. Walensky

出版事項 2013

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Artigo

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11

A phospho-BAD BH3 helix activates glucokinase by a mechanism distinct from that of allosteric activators 著者: Benjamin Szlyk, Craig R. Braun, Sanda Ljubicic, Elaura Patton, Gregory H. Bird, Mayowa Osundiji, Franz M. Matschinsky, Loren D. Walensky, Nika N. Danial

出版事項 2013

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Artigo

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12

Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic 著者: Gregory H. Bird, Navid Madani, Alisa F. Perry, Amy M. Princiotto, Jeffrey G. Supko, Xiaoying He, Evripidis Gavathiotis, Joseph Sodroski, Loren D. Walensky

出版事項 2010

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Artigo

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13

Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices 著者: Elizaveta S. Leshchiner, Andrey A. Parkhitko, Gregory H. Bird, James Luccarelli, Joseph A. Bellairs, Silvia Escudero, Kwadwo Opoku-Nsiah, Marina Godes, Norbert Perrimon, Loren D. Walensky

出版事項 2015

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Artigo

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14

Iterative optimization yields Mcl-1–targeting stapled peptides with selective cytotoxicity to Mcl-1–dependent cancer cells 著者: Raheleh Rezaei Araghi, Gregory H. Bird, Jeremy Ryan, J.M. Jenson, Marina Godes, Jonathan R. Pritz, Robert A. Grant, Anthony Letai, Loren D. Walensky, Amy E. Keating

出版事項 2018

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Artigo

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15

BAX activation is initiated at a novel interaction site 著者: Evripidis Gavathiotis, Motoshi Suzuki, Marguerite L. Davis, Kenneth L. Pitter, Gregory H. Bird, Samuel G. Katz, Ho-Chou Tu, Hyungjin Kim, Emily H. Cheng, Nico Tjandra, Loren D. Walensky

出版事項 2008

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Artigo

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16

Allosteric inhibition of antiapoptotic MCL-1 著者: Susan Lee, Thomas E. Wales, Silvia Escudero, Daniel T. Cohen, James Luccarelli, Catherine G Gallagher, Nicole A. Cohen, Annissa J. Huhn, Gregory H. Bird, John R. Engen, Loren D. Walensky

出版事項 2016

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Artigo

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17

Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration 著者: Sarah E. Pease-Raissi, Maria F. Pazyra‐Murphy, Yihang Li, Franziska Wachter, Yusuke Fukuda, Sara J. Fenstermacher, Lauren A. Barclay, Gregory H. Bird, Loren D. Walensky, Rosalind A. Segal

出版事項 2017

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Artigo

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18

Mucosal delivery of a double-stapled RSV peptide prevents nasopulmonary infection 著者: Gregory H. Bird, Sandhya Boyapalle, Terianne Wong, Kwadwo Opoku-Nsiah, Raminder Bedi, W. Christian Crannell, Alisa F. Perry, Huy Duc Nguyen, Viviana Sampayo, Ankita Devareddy, Subhra Mohapatra, Shyam S. Mohapatra, Loren D. Walensky

出版事項 2014

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Artigo

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19

A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers 著者: James L. LaBelle, Samuel G. Katz, Gregory H. Bird, Evripidis Gavathiotis, Michelle L. Stewart, Chelsea E. Lawrence, Jill K. Fisher, Marina Godes, Kenneth L. Pitter, Andrew L. Kung, Loren D. Walensky

出版事項 2012

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Artigo

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20

Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets 著者: Accalia Fu, Lara van Rooyen, Lindsay Evans, Nina Armstrong, Daina Avizonis, Tatsuya Kin, Gregory H. Bird, Anita Reddy, Edward T. Chouchani, Marc Liesa, Loren D. Walensky, A. M. James Shapiro, Nika N. Danial

出版事項 2021

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Artigo

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検索結果 - Gregory H. Bird

Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress 著者: Loren D. Walensky, Gregory H. Bird

Chemical Synthesis of Hydrocarbon‐Stapled Peptides for Protein Interaction Research and Therapeutic Targeting 著者: Gregory H. Bird, W. Christian Crannell, Loren D. Walensky

Chapter 22 Synthesis and Biophysical Characterization of Stabilized α‐Helices of BCL‐2 Domains 著者: Gregory H. Bird, Federico Bernal, Kenneth L. Pitter, Loren D. Walensky

BH3-Triggered Structural Reorganization Drives the Activation of Proapoptotic BAX 著者: Evripidis Gavathiotis, Denis E. Reyna, Marguerite L. Davis, Gregory H. Bird, Loren D. Walensky

Mechanistic validation of a clinical lead stapled peptide that reactivates p53 by dual HDM2 and HDMX targeting 著者: Franziska Wachter, Ann M. Morgan, Marina Godes, Rida Mourtada, Gregory H. Bird, Loren D. Walensky

Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies 著者: Gregory H. Bird, A. Irimia, Gilad Ofek, Peter D. Kwong, Ian A. Wilson, Loren D. Walensky

Biophysical determinants for cellular uptake of hydrocarbon-stapled peptide helices 著者: Gregory H. Bird, Emanuele Mazzola, Kwadwo Opoku-Nsiah, Margaret Lammert, Marina Godes, Donna Neuberg, Loren D. Walensky

Targeted disruption of the EZH2–EED complex inhibits EZH2-dependent cancer 著者: Woojin Kim, Gregory H. Bird, Tobias Neff, Guoji Guo, Marc A. Kerenyi, Loren D. Walensky, Stuart H. Orkin

Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor 著者: Edward P. Harvey, Hyuk‐Soo Seo, Rachel M. Guerra, Gregory H. Bird, Sirano Dhe‐Paganon, Loren D. Walensky

Multimodal Interaction with BCL-2 Family Proteins Underlies the Proapoptotic Activity of PUMA BH3 著者: Amanda Edwards, Evripidis Gavathiotis, James L. LaBelle, Craig R. Braun, Kwadwo Opoku-Nsiah, Gregory H. Bird, Loren D. Walensky

A phospho-BAD BH3 helix activates glucokinase by a mechanism distinct from that of allosteric activators 著者: Benjamin Szlyk, Craig R. Braun, Sanda Ljubicic, Elaura Patton, Gregory H. Bird, Mayowa Osundiji, Franz M. Matschinsky, Loren D. Walensky, Nika N. Danial

Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic 著者: Gregory H. Bird, Navid Madani, Alisa F. Perry, Amy M. Princiotto, Jeffrey G. Supko, Xiaoying He, Evripidis Gavathiotis, Joseph Sodroski, Loren D. Walensky

Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices 著者: Elizaveta S. Leshchiner, Andrey A. Parkhitko, Gregory H. Bird, James Luccarelli, Joseph A. Bellairs, Silvia Escudero, Kwadwo Opoku-Nsiah, Marina Godes, Norbert Perrimon, Loren D. Walensky

Iterative optimization yields Mcl-1–targeting stapled peptides with selective cytotoxicity to Mcl-1–dependent cancer cells 著者: Raheleh Rezaei Araghi, Gregory H. Bird, Jeremy Ryan, J.M. Jenson, Marina Godes, Jonathan R. Pritz, Robert A. Grant, Anthony Letai, Loren D. Walensky, Amy E. Keating

BAX activation is initiated at a novel interaction site 著者: Evripidis Gavathiotis, Motoshi Suzuki, Marguerite L. Davis, Kenneth L. Pitter, Gregory H. Bird, Samuel G. Katz, Ho-Chou Tu, Hyungjin Kim, Emily H. Cheng, Nico Tjandra, Loren D. Walensky

Allosteric inhibition of antiapoptotic MCL-1 著者: Susan Lee, Thomas E. Wales, Silvia Escudero, Daniel T. Cohen, James Luccarelli, Catherine G Gallagher, Nicole A. Cohen, Annissa J. Huhn, Gregory H. Bird, John R. Engen, Loren D. Walensky

Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration 著者: Sarah E. Pease-Raissi, Maria F. Pazyra‐Murphy, Yihang Li, Franziska Wachter, Yusuke Fukuda, Sara J. Fenstermacher, Lauren A. Barclay, Gregory H. Bird, Loren D. Walensky, Rosalind A. Segal

A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers 著者: James L. LaBelle, Samuel G. Katz, Gregory H. Bird, Evripidis Gavathiotis, Michelle L. Stewart, Chelsea E. Lawrence, Jill K. Fisher, Marina Godes, Kenneth L. Pitter, Andrew L. Kung, Loren D. Walensky

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