Rezultati - Gregory H. Bird

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  1. 1
    Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress

    Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress od Loren D. Walensky, Gregory H. Bird

    Izdano 2014
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  2. 2
    Chemical Synthesis of Hydrocarbon‐Stapled Peptides for Protein Interaction Research and Therapeutic Targeting

    Chemical Synthesis of Hydrocarbon‐Stapled Peptides for Protein Interaction Research and Therapeutic Targeting od Gregory H. Bird, W. Christian Crannell, Loren D. Walensky

    Izdano 2011
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  3. 3
    Chapter 22 Synthesis and Biophysical Characterization of Stabilized α‐Helices of BCL‐2 Domains

    Chapter 22 Synthesis and Biophysical Characterization of Stabilized α‐Helices of BCL‐2 Domains od Gregory H. Bird, Federico Bernal, Kenneth L. Pitter, Loren D. Walensky

    Izdano 2008
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  4. 4
    BH3-Triggered Structural Reorganization Drives the Activation of Proapoptotic BAX

    BH3-Triggered Structural Reorganization Drives the Activation of Proapoptotic BAX od Evripidis Gavathiotis, Denis E. Reyna, Marguerite L. Davis, Gregory H. Bird, Loren D. Walensky

    Izdano 2010
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  5. 5
    Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies

    Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies od Gregory H. Bird, A. Irimia, Gilad Ofek, Peter D. Kwong, Ian A. Wilson, Loren D. Walensky

    Izdano 2014
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  6. 6
    Biophysical determinants for cellular uptake of hydrocarbon-stapled peptide helices

    Biophysical determinants for cellular uptake of hydrocarbon-stapled peptide helices od Gregory H. Bird, Emanuele Mazzola, Kwadwo Opoku-Nsiah, Margaret Lammert, Marina Godes, Donna Neuberg, Loren D. Walensky

    Izdano 2016
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  7. 7
    Targeted disruption of the EZH2–EED complex inhibits EZH2-dependent cancer

    Targeted disruption of the EZH2–EED complex inhibits EZH2-dependent cancer od Woojin Kim, Gregory H. Bird, Tobias Neff, Guoji Guo, Marc A. Kerenyi, Loren D. Walensky, Stuart H. Orkin

    Izdano 2013
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  8. 8
    Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor

    Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor od Edward P. Harvey, Hyuk‐Soo Seo, Rachel M. Guerra, Gregory H. Bird, Sirano Dhe‐Paganon, Loren D. Walensky

    Izdano 2017
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  9. 9
    Multimodal Interaction with BCL-2 Family Proteins Underlies the Proapoptotic Activity of PUMA BH3

    Multimodal Interaction with BCL-2 Family Proteins Underlies the Proapoptotic Activity of PUMA BH3 od Amanda Edwards, Evripidis Gavathiotis, James L. LaBelle, Craig R. Braun, Kwadwo Opoku-Nsiah, Gregory H. Bird, Loren D. Walensky

    Izdano 2013
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  10. 10
    A phospho-BAD BH3 helix activates glucokinase by a mechanism distinct from that of allosteric activators

    A phospho-BAD BH3 helix activates glucokinase by a mechanism distinct from that of allosteric activators od Benjamin Szlyk, Craig R. Braun, Sanda Ljubicic, Elaura Patton, Gregory H. Bird, Mayowa Osundiji, Franz M. Matschinsky, Loren D. Walensky, Nika N. Danial

    Izdano 2013
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  11. 11
    Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic

    Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic od Gregory H. Bird, Navid Madani, Alisa F. Perry, Amy M. Princiotto, Jeffrey G. Supko, Xiaoying He, Evripidis Gavathiotis, Joseph Sodroski, Loren D. Walensky

    Izdano 2010
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  12. 12
    Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices

    Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices od Elizaveta S. Leshchiner, Andrey A. Parkhitko, Gregory H. Bird, James Luccarelli, Joseph A. Bellairs, Silvia Escudero, Kwadwo Opoku-Nsiah, Marina Godes, Norbert Perrimon, Loren D. Walensky

    Izdano 2015
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  13. 13
    Iterative optimization yields Mcl-1–targeting stapled peptides with selective cytotoxicity to Mcl-1–dependent cancer cells

    Iterative optimization yields Mcl-1–targeting stapled peptides with selective cytotoxicity to Mcl-1–dependent cancer cells od Raheleh Rezaei Araghi, Gregory H. Bird, Jeremy Ryan, J.M. Jenson, Marina Godes, Jonathan R. Pritz, Robert A. Grant, Anthony Letai, Loren D. Walensky, Amy E. Keating

    Izdano 2018
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  14. 14
    BAX activation is initiated at a novel interaction site

    BAX activation is initiated at a novel interaction site od Evripidis Gavathiotis, Motoshi Suzuki, Marguerite L. Davis, Kenneth L. Pitter, Gregory H. Bird, Samuel G. Katz, Ho-Chou Tu, Hyungjin Kim, Emily H. Cheng, Nico Tjandra, Loren D. Walensky

    Izdano 2008
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  15. 15
    Allosteric inhibition of antiapoptotic MCL-1

    Allosteric inhibition of antiapoptotic MCL-1 od Susan Lee, Thomas E. Wales, Silvia Escudero, Daniel T. Cohen, James Luccarelli, Catherine G Gallagher, Nicole A. Cohen, Annissa J. Huhn, Gregory H. Bird, John R. Engen, Loren D. Walensky

    Izdano 2016
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  16. 16
    Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration

    Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration od Sarah E. Pease-Raissi, Maria F. Pazyra‐Murphy, Yihang Li, Franziska Wachter, Yusuke Fukuda, Sara J. Fenstermacher, Lauren A. Barclay, Gregory H. Bird, Loren D. Walensky, Rosalind A. Segal

    Izdano 2017
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  17. 17
    Mucosal delivery of a double-stapled RSV peptide prevents nasopulmonary infection

    Mucosal delivery of a double-stapled RSV peptide prevents nasopulmonary infection od Gregory H. Bird, Sandhya Boyapalle, Terianne Wong, Kwadwo Opoku-Nsiah, Raminder Bedi, W. Christian Crannell, Alisa F. Perry, Huy Duc Nguyen, Viviana Sampayo, Ankita Devareddy, Subhra Mohapatra, Shyam S. Mohapatra, Loren D. Walensky

    Izdano 2014
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  18. 18
    A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers

    A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers od James L. LaBelle, Samuel G. Katz, Gregory H. Bird, Evripidis Gavathiotis, Michelle L. Stewart, Chelsea E. Lawrence, Jill K. Fisher, Marina Godes, Kenneth L. Pitter, Andrew L. Kung, Loren D. Walensky

    Izdano 2012
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  19. 19
    Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets

    Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets od Accalia Fu, Lara van Rooyen, Lindsay Evans, Nina Armstrong, Daina Avizonis, Tatsuya Kin, Gregory H. Bird, Anita Reddy, Edward T. Chouchani, Marc Liesa, Loren D. Walensky, A. M. James Shapiro, Nika N. Danial

    Izdano 2021
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  20. 20
    Inhibition of Pro-Apoptotic BAX by a Noncanonical Interaction Mechanism

    Inhibition of Pro-Apoptotic BAX by a Noncanonical Interaction Mechanism od Lauren A. Barclay, Thomas E. Wales, Thomas P. Garner, Franziska Wachter, Susan Lee, Rachel M. Guerra, Michelle L. Stewart, Craig R. Braun, Gregory H. Bird, Evripidis Gavathiotis, John R. Engen, Loren D. Walensky

    Izdano 2015
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