Výsledky vyhledávání - Greg Coffey
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Dual SYK/JAK inhibition overcomes ibrutinib resistance in chronic lymphocytic leukemia: Cerdulatinib, but not ibrutinib, induces apoptosis of tumor cells protected by the microenvi... Autor Ailin Guo, Pin Lu, Greg Coffey, Pamela B. Conley, Anjali Pandey, Y. Lynn Wang
Vydáno 2017Artigo -
2
Increases in Dopamine D3 Receptor Binding in Rats Receiving a Cocaine Challenge at Various Time Points after Cocaine Self-Administration: Implications for Cocaine-Seeking Behavior Autor Janet L. Neisewander, Rita A. Fuchs, Ly T.L. Tran-Nguyen, Suzanne M. Weber, Greg Coffey, Jeffrey N. Joyce
Vydáno 2004Artigo -
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4
Cerdulatinib, a novel dual SYK/JAK kinase inhibitor, has broad anti-tumor activity in both ABC and GCB types of diffuse large B cell lymphoma Autor Jiao Ma, Xing Wei, Greg Coffey, Karen Dresser, Kellie Lu, Ailin Guo, Gordana Raca, Anjali Pandey, Pamela B. Conley, Hongbo Yu, Y. Lynn Wang
Vydáno 2015Artigo -
5
An engineered immunomodulatory IgG1 Fc suppresses autoimmune inflammation through pathways shared with i.v. immunoglobulin Autor Sunny L. Sneed, Brian B. Reese, Ana Fs Laureano, Sneha Ratnapriya, Isabella Fraschilla, Kate L. Jeffrey, Greg Coffey, Pamela B. Conley, Robert M. Anthony
Vydáno 2024Artigo -
6
Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration Autor Julia Hoellenriegel, Greg Coffey, Uma Sinha, Anju Pandey, Mariela Sivina, Alessandra Ferrajoli, Farhad Ravandi, William G. Wierda, Susan O’Brien, Michael J. Keating, JA Burger
Vydáno 2012Artigo -
7
The Selective Syk Inhibitor P505-15 (PRT062607) Inhibits B Cell Signaling and Function In Vitro and In Vivo and Augments the Activity of Fludarabine in Chronic Lymphocytic Leukemia Autor Stephen E. Spurgeon, Greg Coffey, Luke B. Fletcher, Russell T. Burke, Jeffrey W. Tyner, Brian J. Druker, Andreas Betz, Francis DeGuzman, Yvonne Pak, Dale C. Baker, Anjali Pandey, Stanley J. Hollenbach, Uma Sinha, Marc Loriaux
Vydáno 2012Artigo -
8
Results from an open-label phase 2a study of cerdulatinib, a dual spleen tyrosine kinase/janus kinase inhibitor, in relapsed/refractory peripheral T-cell lymphoma Autor Steven M. Horwitz, Tatyana Feldman, Jing Christine Ye, Michael S. Khodadoust, Javier Muñoz, Paul A. Hamlin, Youn H. Kim, Ryan A. Wilcox, Manish R. Patel, Greg Coffey, A. Micheil Innes, Andreas Betz, Jaymes Holland, Cristina B. Guzmán, Sonali M. Smith
Vydáno 2025Artigo -
9
The Dual Syk/JAK Inhibitor Cerdulatinib Antagonizes B-cell Receptor and Microenvironmental Signaling in Chronic Lymphocytic Leukemia Autor Matthew D. Blunt, Stefan Koehrer, Rachel Dobson, Marta Larráyoz, Sarah Wilmore, Alice Hayman, Jack Parnell, Lindsay Smith, Andrew Davies, Peter Johnson, Pamela B. Conley, Anjali Pandey, Jonathan C. Strefford, Freda K. Stevenson, Graham Packham, Francesco Forconi, Greg Coffey, Jan A. Burger, Andrew J. Steele
Vydáno 2016Artigo -
10
Pre-BCR signaling in precursor B-cell acute lymphoblastic leukemia regulates PI3K/AKT, FOXO1 and MYC, and can be targeted by SYK inhibition Autor Stefan Köhrer, Ondřej Havránek, Felix Seyfried, Christian Hurtz, Greg Coffey, E. Kim, Elisa ten Hacken, Ulrich Jäger, Katrina Vanura, Susan O’Brien, Deborah A. Thomas, Hagop M. Kantarjian, Dipanjan Ghosh, Z Wang, M. Zhang, Wencai Ma, Hassan Jumaa, Klaus‐Michael Debatin, Markus Müschen, L H Meyer, R. Eric Davis, Jan A. Burger
Vydáno 2016Artigo -
11
Sialylated IgG induces the transcription factor REST in alveolar macrophages to protect against lung inflammation and severe influenza disease Autor Saborni Chakraborty, Bowie Yik-Ling Cheng, Desmond L. Edwards, Joseph C. González, David Kung‐Chun Chiu, Hong Zheng, Courtney Scallan, Xinrong Guo, Gene S. Tan, Greg Coffey, Pamela B. Conley, Patrick S. Hume, William J. Janssen, Derek E. Byers, Philip A. Mudd, Jeffery K. Taubenberger, Matthew J. Memoli, Mark M. Davis, Katrin F. Chua, Michael Diamond, Evangelos Andreakos, Purvesh Khatri, Taia T. Wang
Vydáno 2024Artigo
Vyhledávací nástroje:
Související témata
Receptor
Biology
Cancer research
Immunology
Tyrosine kinase
Internal medicine
Medicine
Syk
Biochemistry
Bruton's tyrosine kinase
Antibody
Cell biology
Chronic lymphocytic leukemia
Leukemia
Signal transduction
breakpoint cluster region
B cell
Chemistry
Lymphoma
B-cell receptor
Biotechnology
Diffuse large B-cell lymphoma
Genetics
Ibrutinib
Idelalisib
In vitro
In vivo
Inflammation
Kinase
Pharmacology