Resultats de la cerca - Greg Coffey

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  1. 1
    Dual SYK/JAK inhibition overcomes ibrutinib resistance in chronic lymphocytic leukemia: Cerdulatinib, but not ibrutinib, induces apoptosis of tumor cells protected by the microenvironment

    Dual SYK/JAK inhibition overcomes ibrutinib resistance in chronic lymphocytic leukemia: Cerdulatinib, but not ibrutinib, induces apoptosis of tumor cells protected by the microenvi... per Ailin Guo, Pin Lu, Greg Coffey, Pamela B. Conley, Anjali Pandey, Y. Lynn Wang

    Publicat 2017
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  2. 2
    Increases in Dopamine D3 Receptor Binding in Rats Receiving a Cocaine Challenge at Various Time Points after Cocaine Self-Administration: Implications for Cocaine-Seeking Behavior

    Increases in Dopamine D3 Receptor Binding in Rats Receiving a Cocaine Challenge at Various Time Points after Cocaine Self-Administration: Implications for Cocaine-Seeking Behavior per Janet L. Neisewander, Rita A. Fuchs, Ly T.L. Tran-Nguyen, Suzanne M. Weber, Greg Coffey, Jeffrey N. Joyce

    Publicat 2004
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  3. 3
    SYK inhibition and response prediction in diffuse large B-cell lymphoma

    SYK inhibition and response prediction in diffuse large B-cell lymphoma per Shuhua Cheng, Greg Coffey, Xu Hannah Zhang, Rita Shaknovich, Zibo Song, Pin Lu, Anjali Pandey, Ari Melnick, Uma Sinha, Y. Lynn Wang

    Publicat 2011
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  4. 4
    Cerdulatinib, a novel dual SYK/JAK kinase inhibitor, has broad anti-tumor activity in both ABC and GCB types of diffuse large B cell lymphoma

    Cerdulatinib, a novel dual SYK/JAK kinase inhibitor, has broad anti-tumor activity in both ABC and GCB types of diffuse large B cell lymphoma per Jiao Ma, Xing Wei, Greg Coffey, Karen Dresser, Kellie Lu, Ailin Guo, Gordana Raca, Anjali Pandey, Pamela B. Conley, Hongbo Yu, Y. Lynn Wang

    Publicat 2015
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  5. 5
    An engineered immunomodulatory IgG1 Fc suppresses autoimmune inflammation through pathways shared with i.v. immunoglobulin

    An engineered immunomodulatory IgG1 Fc suppresses autoimmune inflammation through pathways shared with i.v. immunoglobulin per Sunny L. Sneed, Brian B. Reese, Ana Fs Laureano, Sneha Ratnapriya, Isabella Fraschilla, Kate L. Jeffrey, Greg Coffey, Pamela B. Conley, Robert M. Anthony

    Publicat 2024
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  6. 6
    Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration

    Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration per Julia Hoellenriegel, Greg Coffey, Uma Sinha, Anju Pandey, Mariela Sivina, Alessandra Ferrajoli, Farhad Ravandi, William G. Wierda, Susan O’Brien, Michael J. Keating, JA Burger

    Publicat 2012
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  7. 7
    The Selective Syk Inhibitor P505-15 (PRT062607) Inhibits B Cell Signaling and Function In Vitro and In Vivo and Augments the Activity of Fludarabine in Chronic Lymphocytic Leukemia

    The Selective Syk Inhibitor P505-15 (PRT062607) Inhibits B Cell Signaling and Function In Vitro and In Vivo and Augments the Activity of Fludarabine in Chronic Lymphocytic Leukemia per Stephen E. Spurgeon, Greg Coffey, Luke B. Fletcher, Russell T. Burke, Jeffrey W. Tyner, Brian J. Druker, Andreas Betz, Francis DeGuzman, Yvonne Pak, Dale C. Baker, Anjali Pandey, Stanley J. Hollenbach, Uma Sinha, Marc Loriaux

    Publicat 2012
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  8. 8
    Results from an open-label phase 2a study of cerdulatinib, a dual spleen tyrosine kinase/janus kinase inhibitor, in relapsed/refractory peripheral T-cell lymphoma

    Results from an open-label phase 2a study of cerdulatinib, a dual spleen tyrosine kinase/janus kinase inhibitor, in relapsed/refractory peripheral T-cell lymphoma per Steven M. Horwitz, Tatyana Feldman, Jing Christine Ye, Michael S. Khodadoust, Javier Muñoz, Paul A. Hamlin, Youn H. Kim, Ryan A. Wilcox, Manish R. Patel, Greg Coffey, A. Micheil Innes, Andreas Betz, Jaymes Holland, Cristina B. Guzmán, Sonali M. Smith

    Publicat 2025
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  9. 9
    The Dual Syk/JAK Inhibitor Cerdulatinib Antagonizes B-cell Receptor and Microenvironmental Signaling in Chronic Lymphocytic Leukemia

    The Dual Syk/JAK Inhibitor Cerdulatinib Antagonizes B-cell Receptor and Microenvironmental Signaling in Chronic Lymphocytic Leukemia per Matthew D. Blunt, Stefan Koehrer, Rachel Dobson, Marta Larráyoz, Sarah Wilmore, Alice Hayman, Jack Parnell, Lindsay Smith, Andrew Davies, Peter Johnson, Pamela B. Conley, Anjali Pandey, Jonathan C. Strefford, Freda K. Stevenson, Graham Packham, Francesco Forconi, Greg Coffey, Jan A. Burger, Andrew J. Steele

    Publicat 2016
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  10. 10
    Pre-BCR signaling in precursor B-cell acute lymphoblastic leukemia regulates PI3K/AKT, FOXO1 and MYC, and can be targeted by SYK inhibition

    Pre-BCR signaling in precursor B-cell acute lymphoblastic leukemia regulates PI3K/AKT, FOXO1 and MYC, and can be targeted by SYK inhibition per Stefan Köhrer, Ondřej Havránek, Felix Seyfried, Christian Hurtz, Greg Coffey, E. Kim, Elisa ten Hacken, Ulrich Jäger, Katrina Vanura, Susan O’Brien, Deborah A. Thomas, Hagop M. Kantarjian, Dipanjan Ghosh, Z Wang, M. Zhang, Wencai Ma, Hassan Jumaa, Klaus‐Michael Debatin, Markus Müschen, L H Meyer, R. Eric Davis, Jan A. Burger

    Publicat 2016
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  11. 11
    Sialylated IgG induces the transcription factor REST in alveolar macrophages to protect against lung inflammation and severe influenza disease

    Sialylated IgG induces the transcription factor REST in alveolar macrophages to protect against lung inflammation and severe influenza disease per Saborni Chakraborty, Bowie Yik-Ling Cheng, Desmond L. Edwards, Joseph C. González, David Kung‐Chun Chiu, Hong Zheng, Courtney Scallan, Xinrong Guo, Gene S. Tan, Greg Coffey, Pamela B. Conley, Patrick S. Hume, William J. Janssen, Derek E. Byers, Philip A. Mudd, Jeffery K. Taubenberger, Matthew J. Memoli, Mark M. Davis, Katrin F. Chua, Michael Diamond, Evangelos Andreakos, Purvesh Khatri, Taia T. Wang

    Publicat 2024
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