Canlyniadau Chwilio - Graham Heap

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  1. 1
    The genetics of chronic inflammatory diseases

    The genetics of chronic inflammatory diseases gan Graham Heap, David A. van Heel

    Cyhoeddwyd 2009
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  2. 2
    The immunogenicity of biosimilar infliximab: can we extrapolate the data across indications?

    The immunogenicity of biosimilar infliximab: can we extrapolate the data across indications? gan Shomron Ben–Horin, Graham Heap, Tariq Ahmad, HoUng Kim, T. Kwon, Yehuda Chowers

    Cyhoeddwyd 2015
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  3. 3
    Comparative methylomics reveals gene-body H3K36me3 in <i>Drosophila</i> predicts DNA methylation and CpG landscapes in other invertebrates

    Comparative methylomics reveals gene-body H3K36me3 in <i>Drosophila</i> predicts DNA methylation and CpG landscapes in other invertebrates gan Lisa Nanty, Guillermo Carbajosa, Graham Heap, Francis L. W. Ratnieks, David A. van Heel, Thomas A. Down, Vardhman K. Rakyan

    Cyhoeddwyd 2011
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  4. 4
    Clinical Features and HLA Association of 5-Aminosalicylate (5-ASA)-induced Nephrotoxicity in Inflammatory Bowel Disease

    Clinical Features and HLA Association of 5-Aminosalicylate (5-ASA)-induced Nephrotoxicity in Inflammatory Bowel Disease gan Graham Heap, Kenji So, Michael N. Weedon, Naomi Edney, Claire Bewshea, Abhey Singh, Vito Annese, John Beckly, D. J. Buurman, Rubina Chaudhary

    Cyhoeddwyd 2015
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  5. 5
    The pattern and outcome of acute severe colitis

    The pattern and outcome of acute severe colitis gan Lotte C. Dinesen, Alissa Walsh, Marijana Nedeljkovic Protic, Graham Heap, Fraser Cummings, Bryan F. Warren, Bruce George, N J McC Mortensen, Simon Travis

    Cyhoeddwyd 2010
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  6. 6
    Exclusive enteral nutrition provides an effective bridge to safer interval elective surgery for adults with Crohn's disease

    Exclusive enteral nutrition provides an effective bridge to safer interval elective surgery for adults with Crohn's disease gan Neel Heerasing, Beth Thompson, Peter Hendy, Graham Heap, G Walker, Rob Bethune, Sarah Mansfield, C. C. Calvert, Nicholas A. Kennedy, Tariq Ahmad, James Goodhand

    Cyhoeddwyd 2017
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  7. 7
    Complex nature of SNP genotype effects on gene expression in primary human leucocytes

    Complex nature of SNP genotype effects on gene expression in primary human leucocytes gan Graham Heap, Gosia Trynka, Ritsert C. Jansen, Marcel Bruinenberg, Morris A. Swertz, Lotte C. Dinesen, Karen A. Hunt, Cisca Wijmenga, David A vanHeel, Lude Franke

    Cyhoeddwyd 2009
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  8. 8
    Tyrosine Kinase 2 Inhibition With Zasocitinib (TAK-279) in Psoriasis

    Tyrosine Kinase 2 Inhibition With Zasocitinib (TAK-279) in Psoriasis gan April W. Armstrong, Melinda Gooderham, Charles Lynde, Catherine Maari, Seth Forman, Lawrence Green, Vivian Laquer, Xinyan Zhang, Nathalie Franchimont, Esha Gangolli, Jessamyn Blau, Yiwei Zhao, Wenwen Zhang, Bhaskar Srivastava, Graham Heap, Kim Papp

    Cyhoeddwyd 2024
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  9. 9
    Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing

    Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing gan Graham Heap, Jennie H. M. Yang, Kate Downes, Barry Healy, Karen A. Hunt, Nicholas Bockett, Lude Franke, P Dubois, Charles A. Mein, Richard Dobson, Thomas J. Albert, Matthew J. Rodesch, David Clayton, John A. Todd, David A. van Heel, Vincent Plagnol

    Cyhoeddwyd 2009
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  10. 10
    Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease

    Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease gan Deborah J. Smyth, Vincent Plagnol, Neil Walker, Jason D. Cooper, Kate Downes, Jennie H. M. Yang, Joanna M. M. Howson, Helen Stevens, Ross McManus, Cisca Wijmenga, Graham Heap, P Dubois, David Clayton, Karen A. Hunt, David A. van Heel, John A. Todd

    Cyhoeddwyd 2008
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  11. 11
    Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

    Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease gan Katrina M. de Lange, Loukas Moutsianas, James Lee, Christopher A Lamb, Yang Luo, Nicholas A. Kennedy, Luke Jostins, Daniel L Rice, Javier Gutierrez‐Achury, Sun‐Gou Ji, Graham Heap, Elaine R. Nimmo, Cathryn Edwards, Paul Henderson, Craig Mowat, Jeremy Sanderson, Jack Satsangi, Alison Simmons, David C. Wilson, Mark Tremelling, Ailsa Hart, Christopher G. Mathew, William G. Newman, Miles Parkes, Charlie W. Lees, Holm H. Uhlig, C J Hawkey, Natalie J. Prescott, Tariq Ahmad, John Mansfield, Carl A. Anderson, Jeffrey C. Barrett

    Cyhoeddwyd 2017
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  12. 12
    Newly identified genetic risk variants for celiac disease related to the immune response

    Newly identified genetic risk variants for celiac disease related to the immune response gan Karen A. Hunt, Alexandra Zhernakova, Graham Turner, Graham Heap, Lude Franke, Marcel Bruinenberg, Jihane Romanos, Lotte C. Dinesen, Anthony W. Ryan, Davinder Panesar, Rhian Gwilliam, Fumihiko Takeuchi, William McLaren, Geoffrey Holmes, P D Howdle, Julian R.F. Walters, David S. Sanders, Raymond J. Playford, Gosia Trynka, Chris J. Mulder, M. Luisa Mearin, Wieke H.M. Verbeek, Valerie Trimble, Fiona Stevens, Colm O’Morain, Nicholas Kennedy, Dermot Kelleher, Daniel J. Pennington, David P. Strachan, Wendy L. McArdle, Charles A. Mein, Martin C. Wapenaar, Panos Deloukas, Ralph McGinnis, Ross McManus, Cisca Wijmenga, David A. van Heel

    Cyhoeddwyd 2008
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  13. 13
    Association of Genetic Variants in <i>NUDT15</i> With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease

    Association of Genetic Variants in <i>NUDT15</i> With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease gan G Walker, James Harrison, Graham Heap, Michiel Voskuil, Vibeke Andersen, Carl A. Anderson, Ashwin N. Ananthakrishnan, Jeffrey C. Barrett, Laurent Beaugerie, Claire Bewshea, Andy T. Cole, Fraser Cummings, Mark Daly, Pierre Ellul, Richard N. Fedorak, Eleonora A. Festen, Timothy H. Florin, Daniel R. Gaya, Jonas Halfvarson, Ailsa Hart, Neel Heerasing, Peter Hendy, Peter M. Irving, Samuel E. Jones, Jukka Koskela, James O. Lindsay, John Mansfield, Dermot McGovern, Miles Parkes, Richard Pollok, S. Ramakrishnan, David S. Rampton, Manuel A. Rivas, Richard K. Russell, Michael Schultz, Shaji Sebastian, Philippe Seksik, Abhey Singh, Kenji So, Harry Sokol, Kavitha Subramaniam, Anthony Todd, Vito Annese, Rinse K. Weersma, Ramnik J. Xavier, Rebecca Ward, Michael N. Weedon, James Goodhand, Nicholas A. Kennedy, Tariq Ahmad

    Cyhoeddwyd 2019
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  14. 14
    HLA-DQA1–HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants

    HLA-DQA1–HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants gan Graham Heap, Michael N. Weedon, Claire Bewshea, Abhey Singh, Mian Chen, Jack Satchwell, J.P. Vivian, Kenji So, P Dubois, Jane M. Andrews, Vito Annese, Peter A. Bampton, Martin Barnardo, Sally Bell, Andy Cole, Susan J. Connor, Tom Creed, Fraser Cummings, Mauro D’Amato, Tawfique K. Daneshmend, Richard N. Fedorak, Timothy H. Florin, Daniel R. Gaya, Emma I. Greig, Jonas Halfvarson, Alisa Hart, Peter M. Irving, Gareth‐Rhys Jones, Amir Karban, Ian C. Lawrance, James Lee, Charlie W. Lees, Raffi Lev‐Tzion, James O. Lindsay, John Mansfield, Joel Mawdsley, Zia Mazhar, Miles Parkes, Kirstie Parnell, Timothy R. Orchard, Graham Radford‐Smith, Richard K. Russell, David Reffitt, Jack Satsangi, Mark S. Silverberg, G Sturniolo, Mark Tremelling, Epameinondas V. Tsianos, David A. van Heel, Alissa Walsh, Gill Watermeyer, Rinse K. Weersma, Sebastian Zeißig, Jamie Rossjohn, Arthur L. Holden, Tariq Ahmad

    Cyhoeddwyd 2014
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  15. 15
    Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population

    Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population gan Manuel A. Rivas, Brandon E. Avila, Jukka Koskela, Hailiang Huang, Christine Stevens, Matti Pirinen, Talin Haritunians, Benjamin M. Neale, Mitja Kurki, Andrea Ganna, Daniel B. Graham, Benjamin Gläser, Inga Peter, Gil Atzmon, Nir Barzilai, Adam P. Levine, Elena Schiff, Nikolas Pontikos, Ben Weisburd, Monkol Lek, Konrad J. Karczewski, Jonathan M. Bloom, Eric Vallabh Minikel, Britt‐Sabina Petersen, Laurent Beaugerie, Philippe Seksik, Jacques Cosnes, Stefan Schreiber, Bernd Bokemeyer, Johannes Bethge, Graham Heap, Tariq Ahmad, Vincent Plagnol, Anthony W. Segal, Stephan R. Targan, Dan Turner, Päivi Saavalainen, Martti Färkkilâ, Kimmo Kontula, Aarno Palotie, Steven R. Brant, Richard H. Duerr, Mark S. Silverberg, John D. Rioux, Rinse K. Weersma, André Franke, Luke Jostins, Carl A. Anderson, Jeffrey C. Barrett, Daniel G. MacArthur, Chaim Jalas, Harry Sokol, Ramnik J. Xavier, Ann E. Pulver, Judy H. Cho, Dermot McGovern, Mark J. Daly

    Cyhoeddwyd 2018
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  16. 16
    Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

    Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease gan Gosia Trynka, Karen A. Hunt, Nicholas Bockett, Jihane Romanos, Vanisha Mistry, Agata Szperl, Sjoerd F. Bakker, Maria Teresa Bardella, Leena Bhaw, Gemma Castillejo, Emilio G. de la Concha, Rodrigo Coutinho de Almeida, Kerith‐Rae Dias, Cleo C. van Diemen, P Dubois, Richard H. Duerr, Sarah Edkins, Lude Franke, Karin Fransén, Javier Cuesta, Graham Heap, Barbara Hrdličková, Sarah Hunt, Leticia Plaza Izurieta, Valentina Izzo, Leo A. B. Joosten, Cordelia Langford, Maria Cristina Mazzilli, Charles A. Mein, Vandana Midah, Mitja Mitrovič, Barbara Mora, Marinita Morelli, Sarah Nutland, Concepción Núñez, Suna Önengüt-Gümüşcü, Kerra Pearce, Mathieu Platteel, Isabel Polanco, Simon Potter, Carmen Ribes‐Koninckx, Isis Ricaño-Ponce, Stephen S. Rich, Anna Rybak, José Luis Santiago, Sabyasachi Senapati, Ajit Sood, Hania Szajewska, Riccardo Troncone, Jezabel Varadé, Chris Wallace, Victorien M. Wolters, Alexandra Zhernakova, B.K. Thelma, Božena Cukrowská, Elena Urcelay, José Ramón Bilbao, M. L. Mearin, Donatella Barisani, Jeffrey C. Barrett, Vincent Plagnol, Panos Deloukas, Cisca Wijmenga, David A. van Heel

    Cyhoeddwyd 2011
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  17. 17
    Multiple common variants for celiac disease influencing immune gene expression

    Multiple common variants for celiac disease influencing immune gene expression gan P Dubois, Gosia Trynka, Lude Franke, Karen A. Hunt, Jihane Romanos, Alessandra Curtotti, Alexandra Zhernakova, Graham Heap, Róza Ádány, Arpo Aromaa, Maria Teresa Bardella, Leonard H. van den Berg, Nicholas Bockett, Emilio G. de la Concha, Bárbara Dema, Rudolf S.N. Fehrmann, Miguel Fernández‐Arquero, Szilvia Fiatal, Elvira Grandone, Peter M. Green, Harry J.M. Groen, Rhian Gwilliam, Roderick H.J. Houwen, Sarah Hunt, Katri Kaukinen, Dermot Kelleher, Ilma R. Korponay–Szabó, Kalle Kurppa, Padraic MacMathúna, Markku Mäki, Maria Cristina Mazzilli, Owen T McCann, M. Luisa Mearin, Charles A. Mein, Muddassar M. Mirza, Vanisha Mistry, Barbara Mora, Katherine I. Morley, Chris J. Mulder, Joseph A. Murray, Concepción Núñez, Elvira Oosterom, Roel A. Ophoff, Isabel Polanco, Leena Peltonen, Mathieu Platteel, Anna Rybak, Veikko Salomaa, Joachim J. Schweizer, Maria Pia Sperandeo, Greetje J. Tack, Graham Turner, Jan H. Veldink, Wieke H.M. Verbeek, Rinse K. Weersma, Victorien M. Wolters, Elena Urcelay, Božena Cukrowská, Luigi Greco, Susan L. Neuhausen, Ross McManus, Donatella Barisani, Panos Deloukas, Jeffrey C. Barrett, Päivi Saavalainen, Cisca Wijmenga, David A. van Heel

    Cyhoeddwyd 2010
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  18. 18
    A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

    A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis gan Manuel A. Rivas, Daniel B. Graham, Patrick Sulem, Christine Stevens, A. Nicole Desch, Philippe Goyette, Daníel F. Guðbjartsson, Ingileif Jónsdóttir, Unnur Þorsteinsdóttir, Frauke Degenhardt, Sören Mucha, Mitja Kurki, Dalin Li, Mauro D’Amato, Vito Annese, Séverine Vermeire, Rinse K. Weersma, Jonas Halfvarson, Paulina Paavola–Sakki, Maarit Lappalainen, Monkol Lek, Beryl B. Cummings, Taru Tukiainen, Talin Haritunians, Leena Halme, Lotta L. E. Koskinen, Ashwin N. Ananthakrishnan, Yang Luo, Graham Heap, Marijn C. Visschedijk, Jeffrey C. Barrett, Kim de Lange, Cathryn Edwards, AL Hart, C J Hawkey, Luke Jostins, Nicholas A. Kennedy, Christopher A Lamb, James Lee, Charlie W. Lees, John Mansfield, Christopher G. Mathew, C. Mowatt, William G. Newman, Elaine Nimmo, Miles Parkes, Martin Pollard, Natalie J. Prescott, Jessica Randall, Daniel L Rice, Jack Satsangi, Alison Simmons, Mark Tremelling, Holm H. Uhlig, David C. Wilson, Clara Abraham, J ACHKAR, Alain Bitton, Gabrielle Boucher, Kenneth Croitoru, Phil Fleshner, Jürgen Glas, Subra Kugathasan, Johan Van Limbergen, Raquel Milgrom, Deborah D. Proctor, Miguel Regueiro, L. Philip Schumm, Yashoda Sharma, Joanne M. Stempak, Stephan R. Targan, M. H. Wang, Daniel G. MacArthur, Benjamin M. Neale, Tariq Ahmad, Carl A. Anderson, Steven R. Brant, Richard H. Duerr, Mark S. Silverberg, Judy H. Cho, Aarno Palotie, Päivi Saavalainen, Kimmo Kontula, Martti Färkkilâ, Dermot McGovern, André Franke, Kāri Stefánsson, John D. Rioux, Ramnik J. Xavier, Mark J. Daly

    Cyhoeddwyd 2016
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  19. 19
    Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study

    Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study gan Nicholas A. Kennedy, Graham Heap, Harry Green, Benjamin Hamilton, Claire Bewshea, G Walker, Amanda Thomas, Rachel Nice, Mandy H. Perry, Sonia Bouri, Neil Chanchlani, Neel Heerasing, Peter Hendy, Simeng Lin, Daniel R. Gaya, Fraser Cummings, Christian P. Selinger, Charlie W. Lees, Ailsa Hart, Miles Parkes, Shaji Sebastian, John Mansfield, Peter M. Irving, James O. Lindsay, Richard K. Russell, Timothy J. McDonald, Dermot McGovern, James Goodhand, Tariq Ahmad, Vinod Patel, Zia Mazhar, Rebecca Saich, Ben Colleypriest, Tony Tham, Tariq Iqbal, Vishal Kaushik, Senthil Murugesan, Salil Singh, Sean Weaver, Cathryn Preston, Assad Butt, Melissa Smith, Dharamveer Basude, Amanda Beale, Sarah Langlands, Natalie Direkze, Miles Parkes, Franco Torrente, Juan De La Revella Negro, Chris Ewen MacDonald, Stephen M. Evans, Anton Gunasekera, Alka Thakur, David Elphick, Achuth Shenoy, Chuka Nwokolo, Anjan Dhar, A.T. Cole, Anurag K. Agrawal, Stephen Bridger, Julie Doherty, Sheldon C. Cooper, Shanika de Silva, Craig Mowat, Phillip Mayhead, Charlie W. Lees, Gareth‐Rhys Jones, Tariq Ahmad, J. W. Hart, Daniel R. Gaya, Richard K. Russell, Lisa Gervais, Paul Dunckley, Tariq Mahmood, Paul Banim, Sunil Sonwalkar, Deb Ghosh, Rosemary Phillips, Amer Azaz, Shaji Sebastian, Richard Shenderey, Lawrence Armstrong, Claire Bell, Radhakrishnan Hariraj, Helen Matthews, Hasnain Jafferbhoy, Christian P. Selinger, Veena Zamvar, John de Caestecker, Anne Willmott, Richard Miller, Palani Sathish Babu, Christos Tzivinikos, Stuart Bloom, Guy Chung‐Faye, Nicholas M. Croft, John Fell, Marcus Harbord, Ailsa Hart, Ben Hope

    Cyhoeddwyd 2019
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  20. 20
    Genetic architecture of human plasma lipidome and its link to cardiovascular disease

    Genetic architecture of human plasma lipidome and its link to cardiovascular disease gan Rubina Tabassum, Joel Rämö, Pietari Ripatti, Jukka Koskela, Mitja Kurki, Juha Karjalainen, Priit Palta, Shabbeer Hassan, Javier Núñez-Fontarnau, Tuomo Kiiskinen, Sanni Söderlund, Niina Matikainen, Mathias J. Gerl, Michał A. Surma, Christian Klose, Nathan O. Stitziel, Hannele Laivuori, Aki S. Havulinna, Susan K. Service, Veikko Salomaa, Matti Pirinen, Anu Jalanko, Jaakko Kaprio, Kati Donner, Mari Kaunisto, Nina Mars, Alexander Dada, Anastasia Shcherban, Andrea Ganna, Arto Lehistö, Elina Kilpeläinen, Georg Brein, Awaisa Ghazal, Jarmo Harju, Kalle Pärn, Pietro Della Briotta Parolo, Risto Kajanne, Susanna Lemmelä, Timo P. Sipilä, Tuomas Sipilä, Ulrike Lyhs, Vincent Llorens, Teemu Niiranen, Kati Kristiansson, Lotta Männikkö, Manuel González Jiménez, Markus Perola, Regis Wong, Terhi Kilpi, Tero Hiekkalinna, Elina Järvensivu, Essi Kaiharju, Hannele Mattsson, Markku Laukkanen, Päivi Laiho, Sini Lähteenmäki, Tuuli Sistonen, Sirpa Soini, Adam Ziemann, Anne Lehtonen, Apinya Lertratanakul, Bob Georgantas, Bridget Riley‐Gillis, Danjuma Quarless, Fedik Rahimov, Graham Heap, Howard J. Jacob, Jeffrey F. Waring, J. Wade Davis, Nizar Smaoui, Relja Popovic, Sahar Esmaeeli, Jeff Waring, Athena Matakidou, Ben Challis, David A. Close, Slavé Petrovski, Antti Karlsson, Johanna Schleutker, Kari Pulkki, Petri Virolainen, Lila Kallio, Graham J. Mann, Sami Heikkinen, Veli‐Matti Kosma, Chia‐Yen Chen, Heiko Runz, Jiang Liu, Paola G. Bronson, Sally John, Sanni Lahdenperä, Susan Eaton, Wei Zhou, Minna Hendolin, Outi Tuovila, Raimo Pakkanen, Joseph Maranville, Keith Usiskin, Marla Hochfeld, Robert Plenge

    Cyhoeddwyd 2019
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