Search Results - Graeme R. Grimes

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  1. 1
    Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors and Contributes to the Regulation of Alternative Splicing

    Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors and Contributes to the Regulation of Alternative Splicing by Madapura M. Pradeepa, Heidi G. Sutherland, Jernej Ule, Graeme R. Grimes, Wendy A. Bickmore

    Published 2012
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  2. 2
    DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans

    DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans by Dáša Longman, Nele Hug, Marianne Keith, Corina Anastasaki, E. Elizabeth Patton, Graeme R. Grimes, Javier F. Cáceres

    Published 2013
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  3. 3
    Histone H3 globular domain acetylation identifies a new class of enhancers

    Histone H3 globular domain acetylation identifies a new class of enhancers by Madapura M. Pradeepa, Graeme R. Grimes, Yatendra Kumar, Gabrielle Olley, Gillian C.A. Taylor, Robert Schneider, Wendy A. Bickmore

    Published 2016
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  4. 4
    Decreased Enhancer-Promoter Proximity Accompanying Enhancer Activation

    Decreased Enhancer-Promoter Proximity Accompanying Enhancer Activation by Nezha S. Benabdallah, Iain Williamson, Robert S. Illingworth, Lauren Kane, Shelagh Boyle, Dipta Sengupta, Graeme R. Grimes, Pierre Therizols, Wendy A. Bickmore

    Published 2019
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  5. 5
    Anterior-posterior differences in HoxD chromatin topology in limb development

    Anterior-posterior differences in HoxD chromatin topology in limb development by Iain Williamson, Ragnhild Eskeland, Laura A. Lettice, Alison E. Hill, Shelagh Boyle, Graeme R. Grimes, Robert E. Hill, Wendy A. Bickmore

    Published 2012
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  6. 6
    Ring1B Compacts Chromatin Structure and Represses Gene Expression Independent of Histone Ubiquitination

    Ring1B Compacts Chromatin Structure and Represses Gene Expression Independent of Histone Ubiquitination by Ragnhild Eskeland, Martin Leeb, Graeme R. Grimes, Clémence Kress, Shelagh Boyle, Duncan Sproul, Nick Gilbert, Yuhong Fan, Arthur I. Skoultchi, Anton Wutz, Wendy A. Bickmore

    Published 2010
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  7. 7
    Human β‐defensin 3 affects the activity of pro‐inflammatory pathways associated with MyD88 and TRIF

    Human β‐defensin 3 affects the activity of pro‐inflammatory pathways associated with MyD88 and TRIF by Fiona Semple, Heather MacPherson, Sheila Webb, Sarah L. Cox, Lucy J. Mallin, Christine Tyrrell, Graeme R. Grimes, Colin A. Semple, Matthew A. Nix, Glenn L. Millhauser, Julia R. Dorin

    Published 2011
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  8. 8
    Opposing Functions of the ETS Factor Family Define Shh Spatial Expression in Limb Buds and Underlie Polydactyly

    Opposing Functions of the ETS Factor Family Define Shh Spatial Expression in Limb Buds and Underlie Polydactyly by Laura A. Lettice, Iain Williamson, John H. Wiltshire, Silvia Peluso, Paul S. Devenney, Alison E. Hill, Abdelkader Essafi, James Hagman, Richard L. Mort, Graeme R. Grimes, Carlo L. DeAngelis, Robert E. Hill

    Published 2012
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  9. 9
    DNA Methylation Directs Polycomb-Dependent 3D Genome Re-organization in Naive Pluripotency

    DNA Methylation Directs Polycomb-Dependent 3D Genome Re-organization in Naive Pluripotency by Katy McLaughlin, Ilya M. Flyamer, John P. Thomson, Heidi K. Mjoseng, Ruchi Shukla, Iain Williamson, Graeme R. Grimes, Robert S. Illingworth, Ian R. Adams, Sari Pennings, Richard R. Meehan, Wendy A. Bickmore

    Published 2019
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  10. 10
    Nuclear RNA forms an interconnected network of transcription-dependent and tunable microgels

    Nuclear RNA forms an interconnected network of transcription-dependent and tunable microgels by Mattia Marenda, Davide Michieletto, Rafal Czapiewski, Jon Stocks, Sophie Winterbourne, Jamilla Miles, Olivia Fleming, Elena Lazarova, Michael Chiang, Graeme R. Grimes, Hannes Becher, Atlanta G. Cook, Davide Marenduzzo, Ryu‐Suke Nozawa, Nick Gilbert

    Published 2024
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  11. 11
    BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange–like syndrome

    BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange–like syndrome by Gabrielle Olley, Morad Ansari, Hemant Bengani, Graeme R. Grimes, James Rhodes, Alex von Kriegsheim, Ana Blatnik, Fiona J. Stewart, Emma Wakeling, Nicola Carroll, Alison Ross, Soo‐Mi Park, Wendy A. Bickmore, Madapura M. Pradeepa, David Fitzpatrick

    Published 2018
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  12. 12
    Ribonuclease H2 mutations induce a <scp>cGAS</scp>/<scp>STING</scp>‐dependent innate immune response

    Ribonuclease H2 mutations induce a <scp>cGAS</scp>/<scp>STING</scp>‐dependent innate immune response by Karen J. Mackenzie, Paula Carroll, Laura A. Lettice, Žygimantė Tarnauskaitė, Kaalak Reddy, Flora Dix, Ailsa Revuelta, E. Abbondati, Rachel E. Rigby, Björn Rabe, Fiona Kilanowski, Graeme R. Grimes, Adeline Fluteau, Paul S. Devenney, Robert E. Hill, Martin A.M. Reijns, Andrew P. Jackson

    Published 2016
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  13. 13
    Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development

    Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development by Martin A.M. Reijns, Björn Rabe, Rachel E. Rigby, Pleasantine Mill, Katy R. Astell, Laura A. Lettice, Shelagh Boyle, Andrea Leitch, Margaret Keighren, Fiona Kilanowski, Paul S. Devenney, David Sexton, Graeme R. Grimes, Ian Holt, Robert E. Hill, Martin S. Taylor, Kirstie A. Lawson, Julia R. Dorin, Andrew P. Jackson

    Published 2012
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  14. 14
    Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis

    Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis by Emma A. Hall, Dhivya Kumar, Suzanna L. Prosser, Patricia L. Yeyati, Vicente Herranz‐Pérez, José Manuel García‐Verdugo, Lorraine Rose, Lisa McKie, Daniel O Dodd, Peter Tennant, Roly Megaw, Laura C. Murphy, Marisa Ferreira, Graeme R. Grimes, Lucy Williams, Tooba Quidwai, Laurence Pelletier, Jeremy F. Reiter, Pleasantine Mill

    Published 2023
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  15. 15
    Structural Variants at the<i>BRCA1/2</i>Loci are a Common Source of Homologous Repair Deficiency in High-grade Serous Ovarian Carcinoma

    Structural Variants at the<i>BRCA1/2</i>Loci are a Common Source of Homologous Repair Deficiency in High-grade Serous Ovarian Carcinoma by Ailith Ewing, Alison Meynert, Michael Churchman, Graeme R. Grimes, Robert L. Hollis, C. Simon Herrington, Tzyvia Rye, Clare Bartos, Ian Croy, Michelle Ferguson, Mairi Lennie, Trevor McGoldrick, Neil McPhail, Nadeem Siddiqui, Suzanne Dowson, Rosalind Glasspool, Melanie Mackean, Fiona Nussey, Brian McDade, Darren Ennis, Lynn McMahon, Athena Matakidou, Brian Dougherty, Ruth March, J. Carl Barrett, Iain A. McNeish, Andrew V. Biankin, Patricia Roxburgh, Charlie Gourley, Colin A. Semple

    Published 2021
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  16. 16
    A prenylated dsRNA sensor protects against severe COVID-19

    A prenylated dsRNA sensor protects against severe COVID-19 by Arthur Wickenhagen, Elena Sugrue, Spyros Lytras, Srikeerthana Kuchi, Marko Noerenberg, Matthew L. Turnbull, Colin Loney, Vanessa Herder, Jay Allan, Innes Jarmson, Natalia Cameron-Ruiz, Margus Varjak, Rute Maria Pinto, Young Seok Lee, Louisa Iselin, Natasha Palmalux, Douglas G. Stewart, Simon Swingler, Edward JD Greenwood, Thomas W.M. Crozier, Quan Gu, Emma L. Davies, Sara Clohisey, Bo Wang, Fábio Trindade Maranhão Costa, Monique Freire Santana, Luíz Carlos de Lima Ferreira, Lee Murphy, Angie Fawkes, Alison Meynert, Graeme R. Grimes, João Luiz Silva‐Filho, Matthias Marti, Joseph Hughes, Richard J. Stanton, Eddie C. Y. Wang, Antonia Ho, Ilan Davis, Ruth F. Jarrett, Alfredo Castelló, David L. Robertson, Malcolm G. Semple, Peter J. M. Openshaw, Massimo Palmarini, Paul J. Lehner, J. Kenneth Baillie, Suzannah J. Rihn, Sam J. Wilson

    Published 2021
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  17. 17
    Genetic mechanisms of critical illness in Covid-19

    Genetic mechanisms of critical illness in Covid-19 by Erola Pairo‐Castineira, Sara Clohisey, Lucija Klarić, Andrew D. Bretherick, Konrad Rawlik, Nick Parkinson, Dorota Pasko, Susan Walker, Anne Richmond, Max Head Fourman, Clark D Russell, Andrew Law, James Furniss, Viktoria‐Eleni Gountouna, Nicola Wrobel, Loukas Moutsianas, Bo Wang, Alison Meynert, Zhijian Yang, Ranran Zhai, Chenqing Zheng, Fiona Griffiths, Wilna Oosthuyzen, Graeme R. Grimes, Barbara Shih, Seán Keating, Marie Zechner, Chris Haley, David J. Porteous, Caroline Hayward, Julian C. Knight, Charlotte Summers, Manu Shankar‐Hari, Paul Klenerman, Lance Turtle, Antonia Ho, Charles Hinds, Peter Horby, Alistair Nichol, David M. Maslove, Lowell Ling, Daniel F. McAuley, Hugh Montgomery, Timothy Walsh, Xia Shen, Kathy Rowan, Angie Fawkes, Lee Murphy, Chris P. Ponting, Albert Tenesa, Mark J. Caulfield, Richard H. Scott, Peter Openshaw, Malcolm G. Semple, Véronique Vitart, James F. Wilson, J. Kenneth Baillie

    Published 2020
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  18. 18
    Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project

    Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project by Chris Taylor, Dawn Field, Susanna‐Assunta Sansone, Jan Aerts, Rolf Apweiler, Michael Ashburner, Catherine A. Ball, Pierre‐Alain Binz, Molly A. Bogue, Tim Booth, Alvis Brāzma, Ryan R. Brinkman, Adam M. Clark, Eric W. Deutsch, Oliver Fiehn, Jennifer Fostel, Peter Ghazal, F. Gibson, Tanya Gray, Graeme R. Grimes, John M. Hancock, Nigel Hardy, Henning Hermjakob, Randall K. Julian, Matthew D. Kane, Carsten Kettner, Christopher R. Kinsinger, Eugene Kolker, Martin Kuiper, Nicolas Le Novère, Jim Leebens‐Mack, Suzanna Lewis, Phillip Lord, Ann‐Marie Mallon, Nishanth Marthandan, Hiroshi Masuya, Ruth McNally, Alexander Mehrle, Norman Morrison, Sandra Orchard, John Quackenbush, James M. Reecy, Donald G. Robertson, Philippe Rocca‐Serra, Henry Rodriguez, Heiko Rosenfelder, Javier Santoyo‐López, Richard H. Scheuermann, Daniel Schober, Barry Smith, Jason Snape, Christian J. Stoeckert, Keith F. Tipton, Peter Sterk, Andreas Untergasser, Jo Vandesompele, Stefan Wiemann

    Published 2008
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  19. 19
    Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

    Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk by Malcolm G. Dunlop, Sara E. Dobbins, Susan M. Farrington, Angela M. Jones, Claire Palles, Nicola Whiffin, Albert Tenesa, Sarah L. Spain, Peter Broderick, Li Yin Ooi, Enric Domingo, Claire Smillie, Marc Henrion, Matthew Frampton, Lynn Martin, Graeme R. Grimes, Maggie Gorman, Colin A. Semple, P Yusanne, Ella Barclay, James Prendergast, Jean‐Baptiste Cazier, Bianca Olver, Steven Penegar, Steven Lubbe, Ian Chander, Luis G. Carvajal–Carmona, Stéphane Ballereau, Amy Lloyd, Jayaram Vijayakrishnan, Lina Zgaga, Igor Rudan, Evropi Τheodoratou, John M. Starr, Ian J. Deary, Iva Kirac, Dujo Kovačević, Lauri A. Aaltonen, Laura Renkonen‐Sinisalo, Jukka‐Pekka Mecklin, Koichi Matsuda, Yusuke Nakamura, Yukinori Okada, Steven Gallinger, David Duggan, David V. Conti, Polly A. Newcomb, John L. Hopper, Mark A. Jenkins, Fredrick R. Schumacher, Graham Casey, Douglas Easton, Mitul Shah, Paul D.P. Pharoah, Annika Lindblom, Tao Liu, Christopher G. Smith, Hannah D. West, Jeremy P. Cheadle, Rachel Midgley, David Kerr, Harry Campbell, Ian Tomlinson, Richard S. Houlston

    Published 2012
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  20. 20
    Genetic mechanisms of critical illness in COVID-19

    Genetic mechanisms of critical illness in COVID-19 by Erola Pairo‐Castineira, Sara Clohisey, Lucija Klarić, Andrew D. Bretherick, Konrad Rawlik, Dorota Pasko, Susan Walker, Nick Parkinson, Max Head Fourman, Clark D Russell, James Furniss, Anne Richmond, Viktoria‐Eleni Gountouna, Nicola Wrobel, David A Harrison, Bo Wang, Yang Wu, Alison Meynert, Fiona Griffiths, Wilna Oosthuyzen, Athanasios Kousathanas, Loukas Moutsianas, Zhijian Yang, Ranran Zhai, Chenqing Zheng, Graeme R. Grimes, Rupert Beale, Jonathan Millar, Barbara Shih, Seán Keating, Marie Zechner, Chris Haley, David J. Porteous, Caroline Hayward, Jian Yang, Julian C. Knight, Charlotte Summers, Manu Shankar‐Hari, Paul Klenerman, Lance Turtle, Antonia Ho, Shona C. Moore, Charles Hinds, Peter Horby, Alistair Nichol, David M. Maslove, Lowell Ling, Danny McAuley, Hugh Montgomery, Timothy Walsh, Alexandre C. Pereira, Alessandra Renieri, Xia Shen, Chris P. Ponting, Angie Fawkes, Albert Tenesa, Mark J. Caulfield, Richard H. Scott, Kathy Rowan, Lee Murphy, Peter Openshaw, Malcolm G. Semple, Andrew Law, Véronique Vitart, James F. Wilson, J. Kenneth Baillie

    Published 2020
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