Search Results - Gowtham Jayakumaran

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  1. 1
    β-Catenin Enhances Oct-4 Activity and Reinforces Pluripotency through a TCF-Independent Mechanism

    β-Catenin Enhances Oct-4 Activity and Reinforces Pluripotency through a TCF-Independent Mechanism by Kevin Kelly, Deborah Y. Ng, Gowtham Jayakumaran, Geoffrey A. Wood, Hiroshi Koide, Bradley W. Doble

    Published 2011
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  2. 2
    A Late Transition in Somatic Cell Reprogramming Requires Regulators Distinct from the Pluripotency Network

    A Late Transition in Somatic Cell Reprogramming Requires Regulators Distinct from the Pluripotency Network by Azadeh Golipour, Laurent David, Yu Liu, Gowtham Jayakumaran, Calley Hirsch, Dan Trcka, Jeffrey L. Wrana

    Published 2012
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  3. 3
    Somatic Mutations of TSC2 or MTOR Characterize a Morphologically Distinct Subset of Sporadic Renal Cell Carcinoma With Eosinophilic and Vacuolated Cytoplasm

    Somatic Mutations of TSC2 or MTOR Characterize a Morphologically Distinct Subset of Sporadic Renal Cell Carcinoma With Eosinophilic and Vacuolated Cytoplasm by Ying‐Bei Chen, Leili Mirsadraei, Gowtham Jayakumaran, Hikmat Al‐Ahmadie, Samson W. Fine, Anuradha Gopalan, S. Joseph Sirintrapun, Satish K. Tickoo, Victor E. Reuter

    Published 2018
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  4. 4
    Cell competition during reprogramming gives rise to dominant clones

    Cell competition during reprogramming gives rise to dominant clones by Nika Shakiba, Ahmed Fahmy, Gowtham Jayakumaran, Sophie McGibbon, Laurent David, Daniel Trcka, Judith Elbaz, Mira C. Puri, András Nagy, Derek van der Kooy, Sidhartha Goyal, Jeffrey L. Wrana, Peter W. Zandstra

    Published 2019
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  5. 5
    A Performance Comparison of Commonly Used Assays to Detect RET Fusions

    A Performance Comparison of Commonly Used Assays to Detect RET Fusions by Soo‐Ryum Yang, Umut Aypar, Ezra Rosen, Douglas A. Mata, Ryma Benayed, Kerry Mullaney, Gowtham Jayakumaran, Yanming Zhang, Denise Frosina, Alexander Drilon, Marc Ladanyi, Achim A. Jungbluth, Natasha Rekhtman, Jaclyn F. Hechtman

    Published 2020
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  6. 6
    Molecular Characterization of Peritoneal Mesotheliomas

    Molecular Characterization of Peritoneal Mesotheliomas by Michael Offin, Soo‐Ryum Yang, Jacklynn V. Egger, Gowtham Jayakumaran, Rowanne S Spencer, Jessica Lopardo, Garrett M. Nash, Andrea Cercek, William D. Travis, Mark G. Kris, Marc Ladanyi, Jennifer L. Sauter, Marjorie G. Zauderer

    Published 2021
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  7. 7
    Reliable Pan-Cancer Microsatellite Instability Assessment by Using Targeted Next-Generation Sequencing Data

    Reliable Pan-Cancer Microsatellite Instability Assessment by Using Targeted Next-Generation Sequencing Data by Sumit Middha, Liying Zhang, Khédoudja Nafa, Gowtham Jayakumaran, Donna Wong, Hyunjae R. Kim, Justyna Sadowska, Michael F. Berger, Deborah F. DeLair, Jinru Shia, Zsofia K. Stadler, David S. Klimstra, Marc Ladanyi, Ahmet Zehir, Jaclyn F. Hechtman

    Published 2017
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  8. 8
    Tubulocystic renal cell carcinoma: a distinct clinicopathologic entity with a characteristic genomic profile

    Tubulocystic renal cell carcinoma: a distinct clinicopathologic entity with a characteristic genomic profile by Judy Sarungbam, Rohit Mehra, Scott A. Tomlins, Steven C. Smith, Gowtham Jayakumaran, Hikmat Al‐Ahmadie, Anuradha Gopalan, S. Joseph Sirintrapun, Samson W. Fine, Yanming Zhang, Mahul B. Amin, Victor E. Reuter, Ying‐Bei Chen, Satish K. Tickoo

    Published 2019
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  9. 9
    Structure–function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targeting

    Structure–function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targeting by Zhenfang Du, Benjamin P. Brown, Soyeon Kim, Donna C. Ferguson, Dean C. Pavlick, Gowtham Jayakumaran, Ryma Benayed, Jean‐Nicolas Gallant, Yunkai Zhang, Yingjun Yan, Monica Red-Brewer, Siraj M. Ali, Alexa B. Schrock, Ahmet Zehir, Marc Ladanyi, Adam W. Smith, Jens Meiler, Christine M. Lovly

    Published 2021
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  10. 10
    Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming

    Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming by Calley Hirsch, Zeynep Coban‐Akdemir, Li Wang, Gowtham Jayakumaran, Dan Trcka, Alexander Weiß, J. Javier Hernández, Qun Pan, Hong Han, Xueping Xu, Zheng Xia, Andrew P. Salinger, Marenda A. Wilson, Frederick S. Vizeacoumar, Alessandro Datti, Wei Li, Austin J. Cooney, Michelle Barton, Benjamin J. Blencowe, Jeffrey L. Wrana, Sharon Dent

    Published 2015
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  11. 11
    Comprehensive assessment of germline pathogenic variant detection in tumor-only sequencing

    Comprehensive assessment of germline pathogenic variant detection in tumor-only sequencing by Panieh Terraf, Fresia Pareja, David Brown, Ozge Ceyhan‐Birsoy, Maksym Misyura, Satshil Rana, Eileen M. O’Reilly, Maria I. Carlo, Carol Aghajanian, Ying L. Liu, Fatemeh Derakhshan, Gowtham Jayakumaran, Britta Weigelt, Michael F. Walsh, Zsofia K. Stadler, Kenneth Offit, Marc Ladanyi, Mark E. Robson, Ahmet Zehir, Jorge S. Reis‐Filho, Diana Mandelker

    Published 2022
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  12. 12
    Diagnostic yield and clinical relevance of expanded genetic testing for cancer patients

    Diagnostic yield and clinical relevance of expanded genetic testing for cancer patients by Ozge Ceyhan‐Birsoy, Gowtham Jayakumaran, Yelena Kemel, Maksym Misyura, Umut Aypar, Sowmya Jairam, Ciyu Yang, Yirong Li, Nikita Mehta, Anna Maio, Angela G. Arnold, Erin Salo‐Mullen, Margaret Sheehan, Aijazuddin Syed, Michael F. Walsh, Maria I. Carlo, Mark E. Robson, Kenneth Offit, Marc Ladanyi, Jorge S. Reis‐Filho, Zsofia K. Stadler, Liying Zhang, Alicia Latham, Ahmet Zehir, Diana Mandelker

    Published 2022
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  13. 13
    The Landscape of Somatic Genetic Alterations in Breast Cancers From ATM Germline Mutation Carriers

    The Landscape of Somatic Genetic Alterations in Breast Cancers From ATM Germline Mutation Carriers by Britta Weigelt, Rui Bi, Rahul Kumar, Pedro Blecua, Diana Mandelker, Felipe C. Geyer, Fresia Pareja, Paul A. James, Fergus J. Couch, Diana Eccles, Fiona M. Blows, Paul D.P. Pharoah, Anqi Li, Pier Selenica, Raymond S. Lim, Gowtham Jayakumaran, Nicola Waddell, Ronglai Shen, Larry Norton, Hannah Y. Wen, Simon N. Powell, Nadeem Riaz, Mark E. Robson, Jorge S. Reis‐Filho, Georgia Chenevix‐Trench

    Published 2018
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  14. 14
    Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer

    Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer by Rona Yaeger, Walid K. Chatila, Marla Lipsyc, Jaclyn F. Hechtman, Andrea Cercek, Francisco Sánchez-Vega, Gowtham Jayakumaran, Sumit Middha, Ahmet Zehir, Mark T.A. Donoghue, Daoqi You, Agnès Viale, Nancy E. Kemeny, Neil H. Segal, Zsofia K. Stadler, Anna M. Varghese, Ritika Kundra, Jianjiong Gao, Aijazuddin Syed, David M. Hyman, Efsevia Vakiani, Neal Rosen, Barry S. Taylor, Marc Ladanyi, Michael F. Berger, David B. Solit, Jinru Shia, Leonard B. Saltz, Nikolaus Schultz

    Published 2018
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  15. 15
    Genetic hallmarks of recurrent/metastatic adenoid cystic carcinoma

    Genetic hallmarks of recurrent/metastatic adenoid cystic carcinoma by Allen S. Ho, Angelica Ochoa, Gowtham Jayakumaran, Ahmet Zehir, Cristina Valero, Justin Tepe, Vladimir Makarov, Martin G. Dalin, Jie He, Mark Bailey, Meagan Montesion, Jeffrey S. Ross, Vincent A. Miller, Lindsay Chan, Ian Ganly, Snjezana Doğan, Nora Katabi, Petros Tsipouras, Patrick K. Ha, Nishant Agrawal, David B. Solit, P. Andrew Futreal, Adel K. El Naggar, Jorge S. Reis‐Filho, Britta Weigelt, Alan L. Ho, Nikolaus Schultz, Timothy A. Chan, Luc G.T. Morris

    Published 2019
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  16. 16
    Accelerating Discovery of Functional Mutant Alleles in Cancer

    Accelerating Discovery of Functional Mutant Alleles in Cancer by Matthew T. Chang, Tripti Shrestha Bhattarai, Alison M. Schram, Craig M. Bielski, Mark T.A. Donoghue, Philip Jonsson, Debyani Chakravarty, Sarah Phillips, Cyriac Kandoth, Alexander Penson, Alexander N. Gorelick, Tambudzai Shamu, Swati Patel, Christopher Harris, Jianjiong Gao, S. Onur Sumer, Ritika Kundra, Pedram Razavi, Bob T. Li, Dalicia N. Reales, Nicholas D. Socci, Gowtham Jayakumaran, Ahmet Zehir, Ryma Benayed, Maria E. Arcila, Sarat Chandarlapaty, Marc Ladanyi, Nikolaus Schultz, José Baselga, Michael F. Berger, Neal Rosen, David B. Solit, David M. Hyman, Barry S. Taylor

    Published 2017
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  17. 17
    Prospective Comprehensive Molecular Characterization of Lung Adenocarcinomas for Efficient Patient Matching to Approved and Emerging Therapies

    Prospective Comprehensive Molecular Characterization of Lung Adenocarcinomas for Efficient Patient Matching to Approved and Emerging Therapies by Emmet Jordan, Hyunjae R. Kim, Maria E. Arcila, David Barron, Debyani Chakravarty, Jianjiong Gao, Matthew T. Chang, Ai Ni, Ritika Kundra, Philip Jonsson, Gowtham Jayakumaran, Sizhi Paul Gao, Hannah C. Johnsen, Aphrothiti J. Hanrahan, Ahmet Zehir, Natasha Rekhtman, Michelle S. Ginsberg, Bob T. Li, Helena A. Yu, Paul K. Paik, Alexander Drilon, Matthew D. Hellmann, Dalicia N. Reales, Ryma Benayed, Valerie W. Rusch, Mark G. Kris, Jamie E. Chaft, José Baselga, Barry S. Taylor, Nikolaus Schultz, Charles M. Rudin, David M. Hyman, Michael F. Berger, David B. Solit, Marc Ladanyi, Gregory J. Riely

    Published 2017
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  18. 18
    Therapeutic Implications of Germline Testing in Patients With Advanced Cancers

    Therapeutic Implications of Germline Testing in Patients With Advanced Cancers by Zsofia K. Stadler, Anna Maio, Debyani Chakravarty, Yelena Kemel, Margaret Sheehan, Erin Salo‐Mullen, Kaitlyn Tkachuk, Christopher J. Fong, Bastien Nguyen, Amanda Erakky, Karen A. Cadoo, Ying L. Liu, Maria I. Carlo, Alicia Latham, Hongxin Zhang, Ritika Kundra, Shaleigh Smith, Jesse Galle, Carol Aghajanian, Nadeem R. Abu‐Rustum, Anna M. Varghese, Eileen M. O’Reilly, Michael J. Morris, Wassim Abida, Michael F. Walsh, Alexander Drilon, Gowtham Jayakumaran, Ahmet Zehir, Marc Ladanyi, Ozge Ceyhan‐Birsoy, David B. Solit, Nikolaus Schultz, Michael F. Berger, Diana Mandelker, Luis A. Díaz, Kenneth Offit, Mark E. Robson

    Published 2021
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  19. 19
    The context-specific role of germline pathogenicity in tumorigenesis

    The context-specific role of germline pathogenicity in tumorigenesis by Preethi Srinivasan, Chaitanya Bandlamudi, Philip Jonsson, Yelena Kemel, Shweta S. Chavan, Allison L. Richards, Alexander Penson, Craig M. Bielski, Christopher J. Fong, Aijazuddin Syed, Gowtham Jayakumaran, Meera Prasad, Jason Hwee, S. Onur Sumer, Ino de Bruijn, Xiang Li, Jianjiong Gao, Nikolaus Schultz, Roy Cambria, Jesse Galle, Semanti Mukherjee, Joseph Vijai, Karen A. Cadoo, Maria I. Carlo, Michael F. Walsh, Diana Mandelker, Ozge Ceyhan‐Birsoy, Jinru Shia, Ahmet Zehir, Marc Ladanyi, David M. Hyman, Liying Zhang, Kenneth Offit, Mark E. Robson, David B. Solit, Zsofia K. Stadler, Michael F. Berger, Barry S. Taylor

    Published 2021
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  20. 20
    Enhanced clinical assessment of hematologic malignancies through routine paired tumor:normal sequencing

    Enhanced clinical assessment of hematologic malignancies through routine paired tumor:normal sequencing by Ryan Ptashkin, Mark D. Ewalt, Gowtham Jayakumaran, Iwona Kiecka, Anita S. Bowman, JinJuan Yao, Jacklyn Casanova, Yun-Te David Lin, Kseniya Petrova‐Drus, Abhinita Mohanty, Ruben Bacares, Jamal Benhamida, Satshil Rana, Anna Razumova, Chad Vanderbilt, Anoop Balakrishnan Rema, Ivelise Rijo, Julie Son-Garcia, Ino de Bruijn, Menglei Zhu, Sean Lachhander, Wei Wang, Mohammad Mahfuzul Haque, Venkatraman Seshan, Jiajing Wang, Ying Liu, Khédoudja Nafa, Laetitia Borsu, Yanming Zhang, Umut Aypar, Sarah P. Suehnholz, Debyani Chakravarty, Jae H. Park, Omar Abdel‐Wahab, Anthony Mato, Wenbin Xiao, Mikhail Roshal, Mariko Yabe, Connie Lee Batlevi, Sergio Giralt, Gilles Salles, Raajit K. Rampal, Martin S. Tallman, Eytan M. Stein, Anas Younes, Ross L. Levine, Miguel‐Angel Perales, Marcel R.M. van den Brink, Ahmet Doǧan, Marc Ladanyi, Michael F. Berger, A. Rose Brannon, Ryma Benayed, Ahmet Zehir, Maria E. Arcila

    Published 2022
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