检索结果 - Gosia Trynka

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  1. 1
    Functional studies of GWAS variants are gaining momentum

    Functional studies of GWAS variants are gaining momentum 由 Florence Lichou, Gosia Trynka

    出版 2020
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  2. 2
    From GWAS to Function: Using Functional Genomics to Identify the Mechanisms Underlying Complex Diseases

    From GWAS to Function: Using Functional Genomics to Identify the Mechanisms Underlying Complex Diseases 由 Eddie Cano-Gamez, Gosia Trynka

    出版 2020
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  3. 3
    Chromatin marks identify critical cell types for fine mapping complex trait variants

    Chromatin marks identify critical cell types for fine mapping complex trait variants 由 Gosia Trynka, Cynthia Sandor, Buhm Han, Han Xu, Barbara E. Stranger, X. Shirley Liu, Soumya Raychaudhuri

    出版 2012
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  4. 4
    Single-cell transcriptomics defines an improved, validated monoculture protocol for differentiation of human iPSC to microglia

    Single-cell transcriptomics defines an improved, validated monoculture protocol for differentiation of human iPSC to microglia 由 Sam Washer, Marta Perez‐Alcantara, Yixi Chen, Juliette Steer, William James, Gosia Trynka, Andrew Bassett, Sally A. Cowley

    出版 2022
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  5. 5
    Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci

    Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci 由 Gosia Trynka, Harm-Jan Westra, Kamil Slowikowski, Xinli Hu, Han Xu, Barbara E. Stranger, Robert J. Klein, Buhm Han, Soumya Raychaudhuri

    出版 2015
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  6. 6
    Potential Celiac Patients: A Model of Celiac Disease Pathogenesis

    Potential Celiac Patients: A Model of Celiac Disease Pathogenesis 由 Maria Pia Sperandeo, Antonella Tosco, Valentina Izzo, Francesca Tucci, Riccardo Troncone, Renata Auricchio, Jihane Romanos, Gosia Trynka, Salvatore Auricchio, Bana Jabrì, Luigi Greco

    出版 2011
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  7. 7
    Complex nature of SNP genotype effects on gene expression in primary human leucocytes

    Complex nature of SNP genotype effects on gene expression in primary human leucocytes 由 Graham Heap, Gosia Trynka, Ritsert C. Jansen, Marcel Bruinenberg, Morris A. Swertz, Lotte C. Dinesen, Karen A. Hunt, Cisca Wijmenga, David A vanHeel, Lude Franke

    出版 2009
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  8. 8
    The influence of a short-term gluten-free diet on the human gut microbiome

    The influence of a short-term gluten-free diet on the human gut microbiome 由 Marc Jan Bonder, Ettje F. Tigchelaar, Xianghang Cai, Gosia Trynka, María Carmen Cénit, Barbara Hrdličková, Huanzi Zhong, Tommi Vatanen, Dirk Gevers, Cisca Wijmenga, Yang Wang, Alexandra Zhernakova

    出版 2016
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  9. 9
    Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease

    Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease 由 Javier Gutierrez‐Achury, Alexandra Zhernakova, Sara L. Pulit, Gosia Trynka, Karen A. Hunt, Jihane Romanos, Soumya Raychaudhuri, David A. van Heel, Cisca Wijmenga, Paul I. W. de Bakker

    出版 2015
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  10. 10
    Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells

    Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells 由 Mary-Ellen Lynall, Blagoje Soskic, James Hayhurst, Jeremy Schwartzentruber, Daniel F. Levey, Gita A. Pathak, Renato Polimanti, Joel Gelernter, Murray B. Stein, Gosia Trynka, Menna R. Clatworthy, Edward T. Bullmore

    出版 2022
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  11. 11
    Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases

    Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases 由 Blagoje Soskic, Eddie Cano-Gamez, Deborah J. Smyth, Wendy C. Rowan, Nikolina Nakić, Jorge Esparza-Gordillo, Lara Bossini‐Castillo, David F. Tough, Christopher Larminie, Paola G. Bronson, David Willé, Gosia Trynka

    出版 2019
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  12. 12
    Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4+ Effector Memory T Cells

    Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4+ Effector Memory T Cells 由 Xinli Hu, Hyun Kim, Towfique Raj, Patrick J. Brennan, Gosia Trynka, Nikola C. Teslovich, Kamil Slowikowski, Wei‐Min Chen, Suna Önengüt, Clare Baecher‐Allan, Philip L. De Jager, Stephen S. Rich, Barbara E. Stranger, Michael B. Brenner, Soumya Raychaudhuri

    出版 2014
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  13. 13
    Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines

    Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines 由 Eddie Cano-Gamez, Blagoje Soskic, Theodoros I. Roumeliotis, Ernest C. So, Deborah J. Smyth, Marta Baldrighi, David Willé, Nikolina Nakić, Jorge Esparza-Gordillo, Christopher Larminie, Paola G. Bronson, David F. Tough, Wendy C. Rowan, Jyoti S. Choudhary, Gosia Trynka

    出版 2020
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  14. 14
    Contrasting the Genetic Background of Type 1 Diabetes and Celiac Disease Autoimmunity

    Contrasting the Genetic Background of Type 1 Diabetes and Celiac Disease Autoimmunity 由 Javier Gutierrez‐Achury, Jihane Romanos, Sjoerd F. Bakker, Vinod Kumar, De Haas, Gosia Trynka, Isis Ricaño-Ponce, Andrea K. Steck, Wei‐Min Chen, Suna Önengüt-Gümüşcü, Suat Şimşek, Marian Rewers, Chris J. Mulder, Ed Liu, Stephen S. Rich, Cisca Wijmenga

    出版 2015
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  15. 15
    Immune disease variants modulate gene expression in regulatory CD4+ T cells

    Immune disease variants modulate gene expression in regulatory CD4+ T cells 由 Lara Bossini‐Castillo, Dafni A. Glinos, Natalia Kunowska, Gosia Golda, Abigail Lamikanra, Michaela Spitzer, Blagoje Soskic, Eddie Cano-Gamez, Deborah J. Smyth, Claire Cattermole, Kaur Alasoo, Alice Mann, Kousik Kundu, Anna Lorenc, Nicole Soranzo, Ian Dunham, David J. Roberts, Gosia Trynka

    出版 2022
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  16. 16
    Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation

    Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation 由 Blagoje Soskic, Eddie Cano-Gamez, Deborah J. Smyth, Kirsty Ambridge, Ziying Ke, Julie C. Matte, Lara Bossini‐Castillo, Joanna Kaplanis, Lucia Ramirez-Navarro, Anna Lorenc, Nikolina Nakić, Jorge Esparza-Gordillo, Wendy C. Rowan, David Willé, David F. Tough, Paola G. Bronson, Gosia Trynka

    出版 2022
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  17. 17
    Evolutionary and Functional Analysis of Celiac Risk Loci Reveals SH2B3 as a Protective Factor against Bacterial Infection

    Evolutionary and Functional Analysis of Celiac Risk Loci Reveals SH2B3 as a Protective Factor against Bacterial Infection 由 Alexandra Zhernakova, Clara C. Elbers, Bart Ferwerda, Jihane Romanos, Gosia Trynka, P Dubois, Carolien G. F. de Kovel, Lude Franke, Marije Oosting, Donatella Barisani, Maria Teresa Bardella, Leo A. B. Joosten, Päivi Saavalainen, David A. van Heel, Carlo Catassi, Mihai G. Netea, Cisca Wijmenga

    出版 2010
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  18. 18
    A Meta-Analysis of Genome-Wide Association Scans Identifies IL18RAP, PTPN2, TAGAP, and PUS10 As Shared Risk Loci for Crohn's Disease and Celiac Disease

    A Meta-Analysis of Genome-Wide Association Scans Identifies IL18RAP, PTPN2, TAGAP, and PUS10 As Shared Risk Loci for Crohn's Disease and Celiac Disease 由 Eleonora A. Festen, Philippe Goyette, Todd J. Green, Gabrielle Boucher, Claudine Beauchamp, Gosia Trynka, P Dubois, Caroline Lagacé, Pieter Stokkers, Daan W. Hommes, Donatella Barisani, Orazio Palmieri, Vito Annese, David A. van Heel, Rinse K. Weersma, Mark J. Daly, Cisca Wijmenga, John D. Rioux

    出版 2011
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  19. 19
    The single-cell eQTLGen consortium

    The single-cell eQTLGen consortium 由 Monique G.P. van der Wijst, DH de Vries, Hilde E. Groot, Gosia Trynka, Chung-Chau Hon, Marc Jan Bonder, Oliver Stegle, Martijn C. Nawijn, Youssef Idaghdour, Pim van der Harst, CJ Ye, Joseph E. Powell, Fabian J. Theis, Ahmed Mahfouz, Matthias Heinig, Lude Franke

    出版 2020
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  20. 20
    Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-like receptors

    Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-like receptors 由 Hafid Laayouni, Marije Oosting, Pierre Luisi, Mihai Ioana, Santos Alonso, Isis Ricaño-Ponce, Gosia Trynka, Alexandra Zhernakova, Theo S. Plantinga, Shih‐Chin Cheng, Jos W.M. van der Meer, Radu A. Popp, Ajit Sood, B.K. Thelma, Cisca Wijmenga, Leo A. B. Joosten, Jaume Bertranpetit, Mihai G. Netea

    出版 2014
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