תוצאות חיפוש - Gosia Trynka
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Functional studies of GWAS variants are gaining momentum מאת Florence Lichou, Gosia Trynka
יצא לאור 2020Artigo -
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Single-cell transcriptomics defines an improved, validated monoculture protocol for differentiation of human iPSC to microglia מאת Sam Washer, Marta Perez‐Alcantara, Yixi Chen, Juliette Steer, William James, Gosia Trynka, Andrew Bassett, Sally A. Cowley
יצא לאור 2022Artigo -
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Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci מאת Gosia Trynka, Harm-Jan Westra, Kamil Slowikowski, Xinli Hu, Han Xu, Barbara E. Stranger, Robert J. Klein, Buhm Han, Soumya Raychaudhuri
יצא לאור 2015Artigo -
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The influence of a short-term gluten-free diet on the human gut microbiome מאת Marc Jan Bonder, Ettje F. Tigchelaar, Xianghang Cai, Gosia Trynka, María Carmen Cénit, Barbara Hrdličková, Huanzi Zhong, Tommi Vatanen, Dirk Gevers, Cisca Wijmenga, Yang Wang, Alexandra Zhernakova
יצא לאור 2016Artigo -
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Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease מאת Javier Gutierrez‐Achury, Alexandra Zhernakova, Sara L. Pulit, Gosia Trynka, Karen A. Hunt, Jihane Romanos, Soumya Raychaudhuri, David A. van Heel, Cisca Wijmenga, Paul I. W. de Bakker
יצא לאור 2015Artigo -
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Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells מאת Mary-Ellen Lynall, Blagoje Soskic, James Hayhurst, Jeremy Schwartzentruber, Daniel F. Levey, Gita A. Pathak, Renato Polimanti, Joel Gelernter, Murray B. Stein, Gosia Trynka, Menna R. Clatworthy, Edward T. Bullmore
יצא לאור 2022Artigo -
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Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases מאת Blagoje Soskic, Eddie Cano-Gamez, Deborah J. Smyth, Wendy C. Rowan, Nikolina Nakić, Jorge Esparza-Gordillo, Lara Bossini‐Castillo, David F. Tough, Christopher Larminie, Paola G. Bronson, David Willé, Gosia Trynka
יצא לאור 2019Artigo -
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Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4+ Effector Memory T Cells מאת Xinli Hu, Hyun Kim, Towfique Raj, Patrick J. Brennan, Gosia Trynka, Nikola C. Teslovich, Kamil Slowikowski, Wei‐Min Chen, Suna Önengüt, Clare Baecher‐Allan, Philip L. De Jager, Stephen S. Rich, Barbara E. Stranger, Michael B. Brenner, Soumya Raychaudhuri
יצא לאור 2014Artigo -
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Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines מאת Eddie Cano-Gamez, Blagoje Soskic, Theodoros I. Roumeliotis, Ernest C. So, Deborah J. Smyth, Marta Baldrighi, David Willé, Nikolina Nakić, Jorge Esparza-Gordillo, Christopher Larminie, Paola G. Bronson, David F. Tough, Wendy C. Rowan, Jyoti S. Choudhary, Gosia Trynka
יצא לאור 2020Artigo -
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Contrasting the Genetic Background of Type 1 Diabetes and Celiac Disease Autoimmunity מאת Javier Gutierrez‐Achury, Jihane Romanos, Sjoerd F. Bakker, Vinod Kumar, De Haas, Gosia Trynka, Isis Ricaño-Ponce, Andrea K. Steck, Wei‐Min Chen, Suna Önengüt-Gümüşcü, Suat Şimşek, Marian Rewers, Chris J. Mulder, Ed Liu, Stephen S. Rich, Cisca Wijmenga
יצא לאור 2015Artigo -
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Immune disease variants modulate gene expression in regulatory CD4+ T cells מאת Lara Bossini‐Castillo, Dafni A. Glinos, Natalia Kunowska, Gosia Golda, Abigail Lamikanra, Michaela Spitzer, Blagoje Soskic, Eddie Cano-Gamez, Deborah J. Smyth, Claire Cattermole, Kaur Alasoo, Alice Mann, Kousik Kundu, Anna Lorenc, Nicole Soranzo, Ian Dunham, David J. Roberts, Gosia Trynka
יצא לאור 2022Artigo -
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Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation מאת Blagoje Soskic, Eddie Cano-Gamez, Deborah J. Smyth, Kirsty Ambridge, Ziying Ke, Julie C. Matte, Lara Bossini‐Castillo, Joanna Kaplanis, Lucia Ramirez-Navarro, Anna Lorenc, Nikolina Nakić, Jorge Esparza-Gordillo, Wendy C. Rowan, David Willé, David F. Tough, Paola G. Bronson, Gosia Trynka
יצא לאור 2022Artigo -
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Evolutionary and Functional Analysis of Celiac Risk Loci Reveals SH2B3 as a Protective Factor against Bacterial Infection מאת Alexandra Zhernakova, Clara C. Elbers, Bart Ferwerda, Jihane Romanos, Gosia Trynka, P Dubois, Carolien G. F. de Kovel, Lude Franke, Marije Oosting, Donatella Barisani, Maria Teresa Bardella, Leo A. B. Joosten, Päivi Saavalainen, David A. van Heel, Carlo Catassi, Mihai G. Netea, Cisca Wijmenga
יצא לאור 2010Artigo -
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A Meta-Analysis of Genome-Wide Association Scans Identifies IL18RAP, PTPN2, TAGAP, and PUS10 As Shared Risk Loci for Crohn's Disease and Celiac Disease מאת Eleonora A. Festen, Philippe Goyette, Todd J. Green, Gabrielle Boucher, Claudine Beauchamp, Gosia Trynka, P Dubois, Caroline Lagacé, Pieter Stokkers, Daan W. Hommes, Donatella Barisani, Orazio Palmieri, Vito Annese, David A. van Heel, Rinse K. Weersma, Mark J. Daly, Cisca Wijmenga, John D. Rioux
יצא לאור 2011Revisão -
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The single-cell eQTLGen consortium מאת Monique G.P. van der Wijst, DH de Vries, Hilde E. Groot, Gosia Trynka, Chung-Chau Hon, Marc Jan Bonder, Oliver Stegle, Martijn C. Nawijn, Youssef Idaghdour, Pim van der Harst, CJ Ye, Joseph E. Powell, Fabian J. Theis, Ahmed Mahfouz, Matthias Heinig, Lude Franke
יצא לאור 2020Artigo -
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Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-like receptors מאת Hafid Laayouni, Marije Oosting, Pierre Luisi, Mihai Ioana, Santos Alonso, Isis Ricaño-Ponce, Gosia Trynka, Alexandra Zhernakova, Theo S. Plantinga, Shih‐Chin Cheng, Jos W.M. van der Meer, Radu A. Popp, Ajit Sood, B.K. Thelma, Cisca Wijmenga, Leo A. B. Joosten, Jaume Bertranpetit, Mihai G. Netea
יצא לאור 2014Artigo
כלי חיפוש:
נושאים קשורים
Biology
Genetics
Gene
Genotype
Single-nucleotide polymorphism
Genome-wide association study
Medicine
Immunology
Disease
Immune system
Internal medicine
Genetic association
Allele
Expression quantitative trait loci
Antigen
Computational biology
Human leukocyte antigen
Quantitative trait locus
SNP
Gene expression
T cell
Bioinformatics
Computer science
Environmental health
Population
Rheumatoid arthritis
Cell biology
Evolutionary biology
Genotyping
Haplotype