نتائج البحث - Giuseppe Orsomando

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  1. 1
    Regulation of NAD biosynthetic enzymes modulates NAD-sensing processes to shape mammalian cell physiology under varying biological cues

    Regulation of NAD biosynthetic enzymes modulates NAD-sensing processes to shape mammalian cell physiology under varying biological cues حسب Silverio Ruggieri, Giuseppe Orsomando, Leonardo Sorci, Nadia Raffaelli

    منشور في 2015
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  2. 2
    Absence of SARM1 Rescues Development and Survival of NMNAT2-Deficient Axons

    Absence of SARM1 Rescues Development and Survival of NMNAT2-Deficient Axons حسب Jonathan Gilley, Giuseppe Orsomando, Isabel Nascimento-Ferreira, Michel P. Coleman

    منشور في 2015
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  3. 3
    Tissue expression and biochemical characterization of human 2‐amino 3‐carboxymuconate 6‐semialdehyde decarboxylase, a key enzyme in tryptophan catabolism

    Tissue expression and biochemical characterization of human 2‐amino 3‐carboxymuconate 6‐semialdehyde decarboxylase, a key enzyme in tryptophan catabolism حسب Lisa Pucci, Silvia Perozzi, Flavio Cimadamore, Giuseppe Orsomando, Nadia Raffaelli

    منشور في 2007
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  4. 4
    Novel assay for simultaneous measurement of pyridine mononucleotides synthesizing activities allows dissection of the <scp>NAD</scp><sup>+</sup> biosynthetic machinery in mammalian cells

    Novel assay for simultaneous measurement of pyridine mononucleotides synthesizing activities allows dissection of the <scp>NAD</scp><sup>+</sup> biosynthetic machinery in mammalian... حسب Federica Zamporlini, Silverio Ruggieri, Francesca Mazzola, Adolfo Amici, Giuseppe Orsomando, Nadia Raffaelli

    منشور في 2014
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  5. 5
    Enzymology of NAD+ homeostasis in man

    Enzymology of NAD+ homeostasis in man حسب Giulio Magni, Adolfo Amici, Monica Emanuelli, Giuseppe Orsomando, Nadia Raffaelli, Silverio Ruggieri

    منشور في 2004
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  6. 6
    A central role for gamma-glutamyl hydrolases in plant folate homeostasis

    A central role for gamma-glutamyl hydrolases in plant folate homeostasis حسب Tariq A. Akhtar, Giuseppe Orsomando, Payam Mehrshahi, Aurora Lara‐Núñez, Malcolm J. Bennett, Jesse F. Gregory, Andrew D. Hanson

    منشور في 2010
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  7. 7
    Metabolic Profiling of Alternative NAD Biosynthetic Routes in Mouse Tissues

    Metabolic Profiling of Alternative NAD Biosynthetic Routes in Mouse Tissues حسب Valerio Mori, Adolfo Amici, Francesca Mazzola, M. Di Stefano, Laura Conforti, Giulio Magni, Silverio Ruggieri, Nadia Raffaelli, Giuseppe Orsomando

    منشور في 2014
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  8. 8
    SARM1 is a multi-functional NAD(P)ase with prominent base exchange activity, all regulated bymultiple physiologically relevant NAD metabolites

    SARM1 is a multi-functional NAD(P)ase with prominent base exchange activity, all regulated bymultiple physiologically relevant NAD metabolites حسب Carlo Alberto Angeletti, Adolfo Amici, Jonathan Gilley, Andrea Loreto, Antonio G. Trapanotto, Christina Antoniou, Elisa Merlini, Michael P. Coleman, Giuseppe Orsomando

    منشور في 2022
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  9. 9
    Reducing expression of NAD<sup>+</sup> synthesizing enzyme NMNAT1 does not affect the rate of Wallerian degeneration

    Reducing expression of NAD<sup>+</sup> synthesizing enzyme NMNAT1 does not affect the rate of Wallerian degeneration حسب Laura Conforti, Lucie Janečková, Diana Wagner, Francesca Mazzola, Lucia Cialabrini, M. Di Stefano, Giuseppe Orsomando, Giulio Magni, Caterina Bendotti, Neil Smyth, Michael P. Coleman

    منشور في 2011
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  10. 10
    Plant γ-Glutamyl Hydrolases and Folate Polyglutamates

    Plant γ-Glutamyl Hydrolases and Folate Polyglutamates حسب Giuseppe Orsomando, Rocío Díaz de la Garza, Brian J. Green, Mingsheng Peng, Philip A. Rea, Thomas J. Ryan, Jesse F. Gregory, Andrew D. Hanson

    منشور في 2005
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  11. 11
    Severe biallelic loss-of-function mutations in nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) in two fetuses with fetal akinesia deformation sequence

    Severe biallelic loss-of-function mutations in nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) in two fetuses with fetal akinesia deformation sequence حسب Marshall Lukacs, Jonathan Gilley, Yi Zhu, Giuseppe Orsomando, Carlo Alberto Angeletti, Jiaqi Liu, Xiuna Yang, Joun Park, Robert J. Hopkin, Michael P. Coleman, R. Grace Zhai, Rolf W. Stottmann

    منشور في 2019
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  12. 12
    NMN Deamidase Delays Wallerian Degeneration and Rescues Axonal Defects Caused by NMNAT2 Deficiency In Vivo

    NMN Deamidase Delays Wallerian Degeneration and Rescues Axonal Defects Caused by NMNAT2 Deficiency In Vivo حسب M. Di Stefano, Andrea Loreto, Giuseppe Orsomando, Valerio Mori, Federica Zamporlini, Richard P. Hulse, Jamie Webster, Lucy F. Donaldson, Martin Gering, Nadia Raffaelli, Michael P. Coleman, Jonathan Gilley, Laura Conforti

    منشور في 2017
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  13. 13
    Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration

    Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration حسب Andrea Loreto, Ciaran Scott Hill, Victoria L. Hewitt, Giuseppe Orsomando, Carlo Alberto Angeletti, Jonathan Gilley, Cristiano Lucci, Álvaro Sánchez-Martínez, Alexander J. Whitworth, Laura Conforti, Federico Dajas‐Bailador, Michael P. Coleman

    منشور في 2019
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  14. 14
    Homozygous NMNAT2 mutation in sisters with polyneuropathy and erythromelalgia

    Homozygous NMNAT2 mutation in sisters with polyneuropathy and erythromelalgia حسب Peter Huppke, Eike Wegener, Jonathan Gilley, Carlo Alberto Angeletti, Ingo Kurth, Joost P.H. Drenth, Christine Stadelmann, Alonso Barrantes‐Freer, Wolfgang Brück, Hölger Thiele, Peter Nürnberg, Jutta Gärtner, Giuseppe Orsomando, Michael P. Coleman

    منشور في 2019
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  15. 15
    Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1

    Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1 حسب Andrea Loreto, Carlo Alberto Angeletti, Weixi Gu, Andrew Osborne, Bart Nieuwenhuis, Jonathan Gilley, Elisa Merlini, Peter Arthur‐Farraj, Adolfo Amici, Zhenyao Luo, Lauren E. Hartley‐Tassell, Thomas Ve, Laura M. Desrochers, Qi Wang, Boštjan Kobe, Giuseppe Orsomando, Michael P. Coleman

    منشور في 2021
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  16. 16
    Author response: Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1

    Author response: Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1 حسب Andrea Loreto, Carlo Alberto Angeletti, Weixi Gu, Andrew Osborne, Bart Nieuwenhuis, Jonathan Gilley, Elisa Merlini, Peter Arthur‐Farraj, Adolfo Amici, Zhenyao Luo, Lauren E. Hartley‐Tassell, Thomas Ve, Laura M. Desrochers, Qi Wang, Boštjan Kobe, Giuseppe Orsomando, Michael P. Coleman

    منشور في 2021
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  17. 17
    A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration

    A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration حسب M. Di Stefano, Isabel Nascimento-Ferreira, Giuseppe Orsomando, Valerio Mori, Jonathan Gilley, Rosalind Brown, Lucie Janečková, Mauricio E. Vargas, L Andre Worrell, Andrea Loreto, Joseph Tickle, Jane Patrick, Jamie Webster, Martina Marangoni, Francesco M. Carpi, Stefania Pucciarelli, Francesca Rossi, Weina Meng, Alvaro Sagasti, Richard R. Ribchester, Giulio Magni, Michael P. Coleman, Laura Conforti

    منشور في 2014
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