Search Results - Giorgio Melloni

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  1. 1
    The origins and genetic interactions of KRAS mutations are allele- and tissue-specific

    The origins and genetic interactions of KRAS mutations are allele- and tissue-specific by Joshua Cook, Giorgio Melloni, D. Gulhan, Peter J. Park, Kevin M. Haigis

    Published 2021
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  2. 2
    INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments

    INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments by Stefano de Pretis, Theresia Kreß, Marco J. Morelli, Giorgio Melloni, Laura Riva, Bruno Amati, Mattia Pelizzola

    Published 2015
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  3. 3
    Per-Particle Cardiovascular Risk of Lipoprotein(a) vs Non-Lp(a) Apolipoprotein B-Containing Lipoproteins

    Per-Particle Cardiovascular Risk of Lipoprotein(a) vs Non-Lp(a) Apolipoprotein B-Containing Lipoproteins by Nicholas Marston, Giorgio Melloni, Sabina A. Murphy, Jakub Morze, Frederick Kamanu, Patrick T. Ellinor, Christian T. Ruff, Marc S. Sabatine

    Published 2024
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  4. 4
    Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns

    Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns by Emma V. Watson, Jake June-Koo Lee, D. Gulhan, Giorgio Melloni, Sergey V. Venev, Rayna Y. Magesh, Abdulrazak Frederick, Kunitoshi Chiba, Eric C. Wooten, Kamila Naxerova, Job Dekker, Peter J. Park, Stephen J. Elledge

    Published 2024
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  5. 5
    Very low-depth whole-genome sequencing in complex trait association studies

    Very low-depth whole-genome sequencing in complex trait association studies by Arthur Gilly, Lorraine Southam, Dániel Süveges, Karoline Kuchenbaecker, Rachel Moore, Giorgio Melloni, Konstantinos Hatzikotoulas, Aliki‐Eleni Farmaki, Graham R. S. Ritchie, Jeremy Schwartzentruber, Petr Danecek, Britt Kilian, Martin Pollard, Xiangyu Ge, Emmanouil Tsafantakis, George Dedoussis, Eleftheria Zeggini

    Published 2018
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  6. 6
    The Effect of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Inhibition on the Risk of Venous Thromboembolism

    The Effect of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Inhibition on the Risk of Venous Thromboembolism by Nicholas Marston, Yared Gurmu, Giorgio Melloni, Marc P. Bonaca, Bariş Gencer, Peter S. Sever, Terje R. Pedersen, Anthony Keech, Carolina Roselli, Steven A. Lubitz, Patrick T. Ellinor, Michelle L. O’Donoghue, Robert P. Giugliano, Christian T. Ruff, Marc S. Sabatine

    Published 2020
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  7. 7
    Predictive Utility of a Coronary Artery Disease Polygenic Risk Score in Primary Prevention

    Predictive Utility of a Coronary Artery Disease Polygenic Risk Score in Primary Prevention by Nicholas Marston, James P. Pirruccello, Giorgio Melloni, Satoshi Koyama, Frederick Kamanu, Lu‐Chen Weng, Carolina Roselli, Yoichiro Kamatani, Issei Komuro, Krishna G. Aragam, Adam S. Butterworth, Kaoru Ito, Steve A. Lubitz, Patrick T. Ellinor, Marc S. Sabatine, Christian T. Ruff

    Published 2022
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  8. 8
    Association of Apolipoprotein B–Containing Lipoproteins and Risk of Myocardial Infarction in Individuals With and Without Atherosclerosis

    Association of Apolipoprotein B–Containing Lipoproteins and Risk of Myocardial Infarction in Individuals With and Without Atherosclerosis by Nicholas Marston, Robert P. Giugliano, Giorgio Melloni, Jeong‐Gun Park, Valerie N. Morrill, Michael A. Blazing, Brian A. Ference, Evan A. Stein, Erik S.G. Stroes, Eugene Braunwald, Patrick T. Ellinor, Steven A. Lubitz, Christian T. Ruff, Marc S. Sabatine

    Published 2021
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  9. 9
    Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations

    Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations by Gaetano Ivan Dellino, Fernando Palluzzi, Andrea M. Chiariello, Rossana Piccioni, Simona Bianco, Laura Furia, Giulia De Conti, Britta A. M. Bouwman, Giorgio Melloni, Davide Guido, Luciano Giacò, Lucilla Luzi, Davide Cittaro, Mario Faretta, Mario Nicodemi, Nicola Crosetto, Pier Giuseppe Pelicci

    Published 2019
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  10. 10
    The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia

    The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia by Anna Giulia Sanarico, Chiara Ronchini, Anna Cleta Croce, Elisa Maria Memmi, U.A. Cammarata, Anna De Antoni, Serena Lavorgna, Mariadomenica Divona, Luciano Giacò, Giorgio Melloni, Andrea Brendolan, Giorgia Simonetti, Giovanni Martinelli, Patrizia Mancuso, Francesco Bertolini, Francesco Lo‐Coco, Gerry Melino, Pier Giuseppe Pelicci, Francesca Bernassola

    Published 2017
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  11. 11
    p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value

    p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value by Angela Santoro, Thalia Vlachou, Lucilla Luzi, Giorgio Melloni, Luca Mazzarella, Errico D’Elia, Xieraili Aobuli, Cristina E. Pasi, Linsey B. Reavie, Paola Bonetti, Simona Punzi, Lucia Casoli, Arianna Sabò, Maria Cristina Moroni, Gaetano Ivan Dellino, Bruno Amati, Francesco Nicassio, Luisa Lanfrancone, Pier Giuseppe Pelicci

    Published 2019
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  12. 12
    A polygenic risk score predicts atrial fibrillation in cardiovascular disease

    A polygenic risk score predicts atrial fibrillation in cardiovascular disease by Nicholas Marston, Amanda C. Garfinkel, Frederick Kamanu, Giorgio Melloni, Carolina Roselli, Petr Jarolı́m, David D. Berg, Deepak L. Bhatt, Marc P. Bonaca, Christopher P. Cannon, Robert P. Giugliano, Michelle L. O’Donoghue, Itamar Raz, Benjamin M. Scirica, Eugene Braunwald, David A. Morrow, Patrick T. Ellinor, Steven A. Lubitz, Marc S. Sabatine, Christian T. Ruff

    Published 2022
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  13. 13
    <i>In Vivo</i> Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype

    <i>In Vivo</i> Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype by Daniela Bossi, Angelo Cicalese, Gaetano Ivan Dellino, Lucilla Luzi, Laura Riva, Carolina D’Alesio, Giuseppe R. Diaferia, Alessandro Carugo, Elena Cavallaro, Rossana Piccioni, Massimo Barberis, Giovanni Mazzarol, Alessandro Testori, Simona Punzi, Isabella Pallavicini, Giulio Tosti, Luciano Giacò, Giorgio Melloni, Timothy P. Heffernan, Gioacchino Natoli, Giulio Draetta, Saverio Minucci, Pier Giuseppe Pelicci, Luisa Lanfrancone

    Published 2016
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  14. 14
    Clinical Application of a Novel Genetic Risk Score for Ischemic Stroke in Patients With Cardiometabolic Disease

    Clinical Application of a Novel Genetic Risk Score for Ischemic Stroke in Patients With Cardiometabolic Disease by Nicholas Marston, Parth Patel, Frederick Kamanu, Francesco Nordio, Giorgio Melloni, Carolina Roselli, Yared Gurmu, Lu‐Chen Weng, Marc P. Bonaca, Robert P. Giugliano, Benjamin M. Scirica, Michelle L. O’Donoghue, Christopher P. Cannon, Christopher D. Anderson, Deepak L. Bhatt, Philippe Gabríel Steg, Marc Cohen, Robert F. Storey, Peter S. Sever, Anthony Keech, Itamar Raz, Ofri Mosenzon, Elliott M. Antman, Eugene Braunwald, Patrick T. Ellinor, Steven A. Lubitz, Marc S. Sabatine, Christian T. Ruff

    Published 2020
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  15. 15
    Somatic mosaicism reveals clonal distributions of neocortical development

    Somatic mosaicism reveals clonal distributions of neocortical development by Martin W. Breuss, Xiaoxu Yang, Johannes C. M. Schlachetzki, Danny Antaki, Addison J. Lana, Xin Xu, Changuk Chung, Guoliang Chai, Valentina Stanley, Qiong Song, Traci Fang Newmeyer, An T. Nguyen, S O'Brien, Marten A. Hoeksema, Beibei Cao, Alexi Nott, Jennifer McEvoy‐Venneri, Martina P. Pasillas, Scott T. Barton, Brett Copeland, Shareef Nahas, Lucitia Van Der Kraan, Yan Ding, Joseph G. Gleeson, Martin W. Breuss, Xiaoxu Yang, Danny Antaki, Changuk Chung, Dan Averbuj, Eric Courchesne, Laurel Ball, Subhojit Roy, Daniel R. Weinberger, Andrew E. Jaffe, Apuã C.M. Paquola, Jennifer A. Erwin, Jooheon Shin, Michael J. McConnell, Richard E. Straub, Rujuta Narurkar, Gary W. Mathern, Christopher A. Walsh, Alice Lee, August Yue Huang, Alissa M. D’Gama, Caroline Dias, Eduardo A. Maury, Javier Ganz, Michael A. Lodato, Michael B. Miller, Pengpeng Li, Rachel E. Rodin, Rebeca Borges-Monroy, Robert Hill, Sara Bizzotto, Sattar Khoshkhoo, Sonia Kim, Zinan Zhou, Peter J. Park, Alison R. Barton, Alon Galor, Chong Chu, Craig L. Bohrson, D. Gulhan, Elaine T. Lim, Eun‐Cheon Lim, Giorgio Melloni, Isidro Cortes, Jake Lee, Joe Luquette, Lixing Yang, Maxwell A. Sherman, Michael E. Coulter, Min‐Seok Kwon, Semin Lee, Soo In Lee, Vinary Viswanadham, Yanmei Dou, Andrew Chess, Attila Jones, Chaggai Rosenbluh, Schahram Akbarian, Ben Langmead, Jeremy Thorpe, Sean Cho, Alexej Abyzov, Taejeong Bae, Yeongjun Jang, Yifan Wang, Cindy Molitor, Mette A. Peters, Fred H. Gage, Meiyan Wang, Patrick Reed, Sara B. Linker, Alexander E. Urban, Bo Zhou, Reenal Pattni, Xiaowei Zhu, Aitor Serres Amero

    Published 2022
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  16. 16
    Control-independent mosaic single nucleotide variant detection with DeepMosaic

    Control-independent mosaic single nucleotide variant detection with DeepMosaic by Xiaoxu Yang, Xin Xu, Martin W. Breuss, Danny Antaki, Laurel Ball, Changuk Chung, Jiawei Shen, Chen Li, Renee D. George, Yifan Wang, Taejeong Bae, Yuhe Cheng, Alexej Abyzov, Liping Wei, Ludmil B. Alexandrov, Jonathan Sebat, Dan Averbuj, Subhojit Roy, Eric Courchesne, August Yue Huang, Alissa M. D’Gama, Caroline Dias, Christopher A. Walsh, Javier Ganz, Michael A. Lodato, Michael Miller, Pengpeng Li, Rachel E. Rodin, Robert Hill, Sara Bizzotto, Sattar Khoshkhoo, Zinan Zhou, Alice Lee, Alison R. Barton, Alon Galor, Chong Chu, Craig L. Bohrson, D. Gulhan, Eduardo A. Maury, Elaine T. Lim, Eun‐Cheon Lim, Giorgio Melloni, Isidro Cortes, Jake Lee, Joe Luquette, Lixing Yang, Maxwell A. Sherman, Michael E. Coulter, Min‐Seok Kwon, Peter J. Park, Rebeca Borges-Monroy, Semin Lee, Sonia Kim, Soo In Lee, Vinary Viswanadham, Yanmei Dou, Andrew Chess, Attila Jones, Chaggai Rosenbluh, Schahram Akbarian, Ben Langmead, Jeremy Thorpe, Sean Cho, Andrew E. Jaffe, Apuã C.M. Paquola, Daniel M. Weinberger, Jennifer A. Erwin, Jooheon Shin, Michael V. McConnell, Richard E. Straub, Rujuta Narurkar, Yeongjun Jang, Cindy Molitor, Mette A. Peters, Fred H. Gage, Meiyan Wang, Patrick Reed, Sara B. Linker, Alexander E. Urban, Bo Zhou, Xiaowei Zhu, Aitor Serres Amero, David Juan, Inna Povolotskaya, Irene Lobón, Manuel Solis Moruno, Raquel García-Pérez, Tomàs Marquès‐Bonet, Eduardo Soriano, Gary W. Mathern, Diane A. Flasch, Trenton J. Frisbie, Huira C. Kopera, Jeffrey M. Kidd, John B. Moldovan, John V. Moran, Kenneth Y. Kwan, Ryan E. Mills, Sarah B. Emery, Weichen Zhou

    Published 2023
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  17. 17
    Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

    Genetic drivers of heterogeneity in type 2 diabetes pathophysiology by Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J. Taylor, Xianyong Yin, Kimberly Lorenz, Ravi Mandla, Alicia Huerta-Chagoya, Giorgio Melloni, Stavroula Kanoni, Nigel W. Rayner, Ozvan Bocher, Ana Luiza Arruda, Kyuto Sonehara, Shinichi Namba, Simon S. K. Lee, Michael Preuß, Lauren E. Petty, Philip Schroeder, Brett Vanderwerff, Mart Kals, Fiona Bragg, Kuang Lin, Xiuqing Guo, Weihua Zhang, Jie Yao, Young Jin Kim, Mariaelisa Graff, Fumihiko Takeuchi, Jana Nano, Amel Lamri, Masahiro Nakatochi, Sanghoon Moon, Robert A. Scott, James P. Cook, Jung‐Jin Lee, Ian Pan, Daniel Taliun, Esteban J. Parra, Jin Fang Chai, Lawrence F. Bielak, Yasuharu Tabara, Yang Hai, Guðmar Þorleifsson, Niels Grarup, Tamar Sofer, Matthias Wuttke, Chloé Sarnowski, Christian Gieger, Darryl Nousome, Stella Trompet, Soo‐Heon Kwak, Jirong Long, Meng Sun, Tong Lin, Wei‐Min Chen, Suraj S. Nongmaithem, Raymond Noordam, Victor Lim, Claudia H.T. Tam, Yoonjung Yoonie Joo, Chien-Hsiun Chen, Laura M. Raffield, Bram P. Prins, Aude Nicolas, Lisa R. Yanek, Guanjie Chen, Jennifer A. Brody, Edmond K. Kabagambe, Ping An, Anny H. Xiang, Hyeok Sun Choi, Brian E. Cade, Jingyi Tan, K. Alaine Broadaway, Alice Williamson, Zoha Kamali, Jinrui Cui, Manonanthini Thangam, Linda S. Adair, Adebowale Adeyemo, Carlos A. Aguilar‐Salinas, Tarunveer S. Ahluwalia, Sonia S. Anand, Alain G. Bertoni, Jette Bork‐Jensen, Ivan Brandslund, Thomas A. Buchanan, Charles Burant, Adam S. Butterworth, Mickaël Canouil, Juliana C.N. Chan, Li-Ching Chang, Miao-Li Chee, Ji Chen, Shyh‐Huei Chen, Yuan‐Tsong Chen, Zhengming Chen, Lee‐Ming Chuang, Mary Cushman

    Published 2024
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