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The Evolving Genomic Landscape of Barrett’s Esophagus and Esophageal Adenocarcinoma av Gianmarco Contino, Thomas L. Vaughan, David C. Whiteman, Rebecca C. Fitzgerald

Publicerad 2017

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Lysine-specific Demethylase 2B (KDM2B)-let-7-Enhancer of Zester Homolog 2 (EZH2) Pathway Regulates Cell Cycle Progression and Senescence in Primary Cells av Alexandros Tzatsos, Polina Paskaleva, Stephania Lymperi, Gianmarco Contino, Svetlana Stoykova, Zhao Chen, Kwok‐Kin Wong, Nabeel Bardeesy

Publicerad 2011

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3

KDM2B promotes pancreatic cancer via Polycomb-dependent and -independent transcriptional programs av Alexandros Tzatsos, Polina Paskaleva, Francesco Ferrari, Vikram Deshpande, Svetlana Stoykova, Gianmarco Contino, Kwok‐Kin Wong, Fei Lan, Patrick Trojer, Peter J. Park, Nabeel Bardeesy

Publicerad 2013

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4

<i>STAT3</i> Plays a Critical Role in <i>KRAS</i>-Induced Pancreatic Tumorigenesis av Ryan B. Corcoran, Gianmarco Contino, Vikram Deshpande, Alexandros Tzatsos, Claudius Conrad, Cyril H. Benes, David E. Levy, Jeffrey Settleman, Jeffrey A. Engelman, Nabeel Bardeesy

Publicerad 2011

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5

TGF-β and αvβ6 Integrin Act in a Common Pathway to Suppress Pancreatic Cancer Progression av Aram F. Hezel, Vikram Deshpande, Stephanie M. Zimmerman, Gianmarco Contino, Brinda Alagesan, Michael R. O’Dell, Lee B. Rivera, Jay Harper, Scott Lonning, Rolf A. Brekken, Nabeel Bardeesy

Publicerad 2012

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6

Combined MEK and PI3K Inhibition in a Mouse Model of Pancreatic Cancer av Brinda Alagesan, Gianmarco Contino, Alexander R. Guimarães, Ryan B. Corcoran, Vikram Deshpande, Gregory R. Wojtkiewicz, Aram F. Hezel, Kwok‐Kin Wong, Massimo Loda, Ralph Weissleder, Cyril H. Benes, Jeffrey A. Engelman, Nabeel Bardeesy

Publicerad 2014

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7

Pancreatic cancers require autophagy for tumor growth av Shenghong Yang, Xiaoxu Wang, Gianmarco Contino, Marc Liesa, Ergün Sahin, Haoqiang Ying, Alexandra S. Bause, Yinghua Li, Jayne M. Stommel, Giacomo Dell’Antonio, Josef Mautner, Giovanni Tonon, Marcia C. Haigis, Orian S. Shirihai, Claudio Doglioni, Nabeel Bardeesy, Alec C. Kimmelman

Publicerad 2011

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The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic av Alexander M. Frankell, Sriganesh Jammula, Xiaodun Li, Gianmarco Contino, Sarah Killcoyne, Sujath Abbas, Juliane Perner, Lawrence Bower, Ginny Devonshire, E. Ococks, Nicola Grehan, James Mok, Maria O’Donovan, Shona MacRae, Matthew Eldridge, Simon Tavaré, Rebecca C. Fitzgerald

Publicerad 2019

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9

RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis av Min Yu, David T. Ting, Shannon L. Stott, Ben S. Wittner, Fatih Ozsolak, Suchismita Paul, Jordan C. Ciciliano, Malgorzata E. Smas, Daniel Winokur, Anna J. Gilman, Matthew Ulman, Kristina Xega, Gianmarco Contino, Brinda Alagesan, Brian W. Brannigan, Patrice M. Milos, David P. Ryan, Lecia V. Sequist, Nabeel Bardeesy, Sridhar Ramaswamy, Mehmet Toner, Shyamala Maheswaran, Daniel A. Haber

Publicerad 2012

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10

Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance av Maria Secrier, Xiaodun Li, Nadeera de Silva, Matthew Eldridge, Gianmarco Contino, Jan Bornschein, Shona MacRae, Nicola Grehan, Maria O’Donovan, Ahmad Miremadi, Tsun-Po Yang, Lawrence Bower, Hamza Chettouh, Jason Crawte, Núria Galeano-Dalmau, Anna M. Grabowska, John Saunders, Tim Underwood, Nicola Waddell, Andrew P. Barbour, Barbara Nutzinger, Achilleas Achilleos, Paul A. Edwards, Andy G. Lynch, Simon Tavaré, Rebecca C. Fitzgerald

Publicerad 2016

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Errata/Corrigenda

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Multicentre cohort study to define and validate pathological assessment of response to neoadjuvant therapy in oesophagogastric adenocarcinoma av Fergus Noble, Megan Lloyd, Richard Turkington, Ewen A. Griffiths, Maria O’Donovan, J. Robert O’Neill, S Mercer, Simon L. Parsons, Rebecca C. Fitzgerald, Tim Underwood, A Noorani, Rachael Fels Elliott, Zarah Abdullahi, Rachel de la Rue, Jan Bornschein, Shona MacRae, Barbara Nutzinger, Nicola Grehan, Gianmarco Contino, Jason Crawte, Paul A. Edwards, Ahmad Miremadi, Shalini Malhotra, Annette Hayden, Rob F. Walker, Christopher J. Peters, G Hannah, Richard Hardwick, Jim Davies, Hugo Ford, D. Gilligan, Peter Safranek, Andrew Hindmarsh, Vijayendran Sujendran, Nicholas Carroll, Damien McManus, Stephen J. Hayes, Yeng Ang, Shaun R. Preston, Sarah Oakes, Izhar Bagwan, Richard J.E. Skipworth, Vicki Save, Ted R. Hupp, Susana Puig, M Bedford, Philippe Tanière, J Whiting, James Byrne, Jamie Kelly, Jack Owsley, Charles Crichton, H. Barr, Neil A. Shepherd, Oliver Old, Jesper Lagergren, J Gossage, Andrew Davies, Fuju Chang, Janine Zylstra, Grant Sanders, Richard Berrisford, Christopher Harden, David Bunting, Michael Lewis, E Cheong, Bhaskar Kumar, James H. Saunders, Irshad Soomro, Ravinder Vohra, John P. Duffy, Philip Kaye, Anna M. Grabowska, Laurence Lovat, Rehan Haidry, V Eneh, Laszlo Igali, I. Welch, Michael Scott, Sharmila Sothi, Sari Suortamo, Suzy Lishman, Duncan Beardsmore, Rupesh Sutaria, Maria Secrier, Matthew Eldridge, Lawrence Bower, Andy G. Lynch, Simon Tavaré

Publicerad 2017

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Machine learning to predict early recurrence after oesophageal cancer surgery av Saqib Rahman, Robert Walker, Megan Lloyd, Leena Grace Beslin, G.I. van Boxel, B. Feike Kingma, Jelle P. Ruurda, Richard van Hillegersberg, Scott Harris, Simon L. Parsons, S Mercer, Ewen A. Griffiths, J. Robert O’Neill, Richard Turkington, Rebecca C. Fitzgerald, Tim Underwood, Ayesha Noorani, Rachael Fels Elliott, Paul A. Edwards, Nicola Grehan, Barbara Nutzinger, Jason Crawte, Hamza Chettouh, Gianmarco Contino, Xiaodun Li, Eleanor Gregson, Sebastian Zeki, Rachel de la Rue, Shalini Malhotra, Simon Tavaré, Andy G. Lynch, Mike L. Smith, Jim Davies, Charles Crichton, Nick Carroll, Peter Safranek, Andrew Hindmarsh, Vijayendran Sujendran, Stephen J. Hayes, Yeng Ang, Shaun R. Preston, Sarah Oakes, Izhar Bagwan, Vicki Save, Richard J. E. Skipworth, Ted R. Hupp, J. Robert O’Neill, Olga Tucker, Andrew D. Beggs, Philippe Tanière, Susana Puig, Tim Underwood, Fergus Noble, James Byrne, Jamie Kelly, Jack Owsley, Hugh Barr, Neil A. Shepherd, Oliver Old, Jesper Lagergren, James Gossage, Fuju Chang, Janine Zylstra, Vicky Goh, Francesca D. Ciccarelli, Grant Sanders, Richard Berrisford, Catherine Harden, David Bunting, M. H. Lewis, Ed Cheong, Bhaskar Kumar, Simon L. Parsons, Irshad Soomro, Philip Kaye, John Saunders, Laurence Lovat, Rehan Haidry, Victor Eneh, Laszlo Igali, Michael J. Scott, Shamila Sothi, Sari Suortamo, Suzy Lishman, George B. Hanna, Christopher J. Peters, Anna M. Grabowska

Publicerad 2020

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13

Disentangling oncogenic amplicons in esophageal adenocarcinoma av Alvin Wei Tian Ng, Dylan Peter McClurg, Ben Wesley, Shahriar A. Zamani, Emily L. Black, Ahmad Miremadi, Olivier Giger, Rogier ten Hoopen, Ginny Devonshire, Aisling M. Redmond, Nicola Grehan, Sriganesh Jammula, Adrienn Blasko, Xiaodun Li, Samuel Aparício, Simon Tavaré, Paul A. Edwards, Nicola Grehan, Barbara Nutzinger, Christine Loreno, Sujath Abbas, Adam Freeman, Elizabeth Smyth, Maria O’Donovan, Ahmad Miremadi, Shalini Malhotra, Monika Tripathi, Calvin Cheah, Hannah Coles, Curtis Millington, Matthew Eldridge, Maria Secrier, Sriganesh Jammula, Jim Davies, Charles Crichton, Nick Carroll, Richard Hardwick, Peter Safranek, Andrew Hindmarsh, Vijayendran Sujendran, Stephen J. Hayes, Yeng Ang, Andrew D Sharrocks, Shaun R. Preston, Izhar Bagwan, Vicki Save, Richard J. E. Skipworth, Ted R. Hupp, J. Robert O’Neill, Olga Tucker, Andrew D. Beggs, Philippe Tanière, Susana Puig, Gianmarco Contino, Tim Underwood, Robert Walker, Ben Grace, Jesper Lagergren, James Gossage, Andrew Davies, Fuju Chang, Ula Mahadeva, Vicky Goh, Francesca D. Ciccarelli, Grant Sanders, Richard Berrisford, David Tsz Chung Chan, Ed Cheong, Bhaskar Kumar, L. Sreedharan, Simon L. Parsons, Irshad Soomro, Philip Kaye, John Saunders, Laurence Lovat, Rehan Haidry, Michael Scott, Sharmila Sothi, Suzy Lishman, George B. Hanna, Christopher J. Peters, Krishna Moorthy, Anna M. Grabowska, Richard Turkington, Damian McManus, Helen G. Coleman, Russell Petty, Freddie Bartlet, Karol Nowicki-Osuch, Rebecca C. Fitzgerald

Publicerad 2024

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14

Context-dependent effects of CDKN2A and other 9p21 gene losses during the evolution of esophageal cancer av Piyali Ganguli, Celia De Los Angeles Colomina Basanta, Amelia Acha‐Sagredo, Hrvoje Mišetić, Maria Armero, Akram Mendez, Aeman Zahra, Ginny Devonshire, Gavin Kelly, Adam Freeman, Mary Green, Emma Nye, Anita Bichisecchi, Paola Bonfanti, Rebecca C. Fitzgerald, Paul A. Edwards, Nicola Grehan, Barbara Nutzinger, Aisling M. Redmond, Christine Loreno, Sujath Abbas, Adam Freeman, Elizabeth Smyth, Maria O’Donovan, Ahmad Miremadi, Shalini Malhotra, Monika Tripathi, Hannah Coles, Curtis Millington, Matthew Eldridge, Maria Secrier, Ginny Devonshire, Jim Davies, Charles Crichton, Nick Carroll, Richard Hardwick, Peter Safranek, Andrew Hindmarsh, Vijayendran Sujendran, Stephen J. Hayes, Yeng Ang, Andrew D Sharrocks, Shaun R. Preston, Izhar Bagwan, Vicki Save, Richard J.E. Skipworth, Ted R. Hupp, J. Robert O’Neill, Olga Tucker, Andrew D. Beggs, Philippe Tanière, Susana Puig, Gianmarco Contino, Tim Underwood, Robert Walker, Ben Grace, Jesper Lagergren, James Gossage, Andrew Davies, Fuju Chang, Ula Mahadeva, Vicky Goh, Francesca D. Ciccarelli, Grant Sanders, Richard Berrisford, David Tsz Chung Chan, Ed Cheong, Bhaskar Kumar, Loveena Sreedharan, Simon L. Parsons, Irshad Soomro, Philip Kaye, John Saunders, Laurence Lovat, Rehan Haidry, Michael A. Scott, Sharmila Sothi, Suzy Lishman, George B. Hanna, Christopher J. Peters, Krishna Moorthy, Anna M. Grabowska, Richard Turkington, Damian McManus, Helen G. Coleman, Russell Petty, Freddie Bartlett, Manuel Rodriguez‐Justo, Jo Spencer, Rebecca C. Fitzgerald, Francesca D. Ciccarelli

Publicerad 2025

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15

Identification of Prognostic Phenotypes of Esophageal Adenocarcinoma in 2 Independent Cohorts av Tarek Sawas, Sarah Killcoyne, Prasad G. Iyer, Kenneth K Wang, Thomas C. Smyrk, John B. Kisiel, Yi Qin, David A. Ahlquist, Anil K. Rustgi, Rui J. Costa, Moritz Gerstung, Rebecca C. Fitzgerald, David A. Katzka, Ayesha Noorani, Paul A. Edwards, Nicola Grehan, Barbara Nutzinger, Caitriona Hughes, Elwira Fidziukiewicz, Jan Bornschein, Shona MacRae, Jason Crawte, Gianmarco Contino, Xiaodun Li, Rachel de la Rue, Maria O’Donovan, Ahmad Miremad, Shalini Malhotra, Monika Tripathi, Simon Tavaré, Andy G. Lynch, Matthew Eldridge, Maria Secrier, Lawrence Bower, Ginny Devonshire, Juliane Perner, Sriganesh Jammula, Jim Davies, Charles Crichton, Nick Carroll, Peter Safranek, Andrew Hindmarsh, Vijayendran Sujendran, Stephen J. Hayes, Yeng Ang, Shaun R. Preston, Sarah Oakes, Izhar Bagwan, Vicki Save, Richard J.E. Skipworth, Ted R. Hupp, J. Robert O’Neill, Olga Tucker, Andrew D. Beggs, Philippe Tanière, Susana Puig, Tim Underwood, Fergus Noble, Jack Owsley, Hugh Barr, Neil A. Shepherd, Oliver Old, Jesper Lagergren, James Gossage, Andrew Davies, Fuju Chang, Janine Zylstra, Ula Mahadeva, Vicky Goh, Francesca D. Ciccarelli, Grant Sanders, Richard Berrisford, Catherine Harden, David Bunting, M. H. Lewis, Ed Cheong, Bhaskar Kumar, Simon L. Parsons, Irshad Soomro, Philip Kaye, John R. Saunders, Laurence Lovat, Rehan Haidry, Victor Eneh, Laszlo Igali, Michael Scott, Sharmila Sothi, Sari Suortamo, Suzy Lishman, George B. Hanna, Christopher J. Peters, Anna M. Grabowska, Richard Turkington

Publicerad 2018

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16

Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma av Thanos P. Mourikis, Lorena Benedetti, Elizabeth Foxall, Damjan Temelkovski, Joel Nulsen, Juliane Perner, Matteo Cereda, Jesper Lagergren, Michael Howell, Christopher Yau, Rebecca C. Fitzgerald, Paola Scaffidi, Ayesha Noorani, Paul A. Edwards, Rachael Fels Elliott, Nicola Grehan, Barbara Nutzinger, Caitriona Hughes, Elwira Fidziukiewicz, Jan Bornschein, Shona MacRae, Jason Crawte, Alex Northrop, Gianmarco Contino, Xiaodun Li, Rachel de la Rue, Annalise Katz‐Summercorn, Sujath Abbas, Daniel Loureda, Maria O’Donovan, Ahmad Miremadi, Shalini Malhotra, Monika Tripathi, Simon Tavaré, Andy G. Lynch, Matthew Eldridge, Maria Secrier, Lawrence Bower, Ginny Devonshire, Sriganesh Jammula, Jim Davies, Charles Crichton, Nick Carroll, Peter Safranek, Andrew Hindmarsh, Vijayendran Sujendran, Stephen J. Hayes, Yeng Ang, Andrew D Sharrocks, Shaun R. Preston, Sarah Oakes, Izhar Bagwan, Vicki Save, Richard J. E. Skipworth, Ted R. Hupp, J. Robert O’Neill, Olga Tucker, Andrew D. Beggs, Philippe Tanière, Susana Puig, Tim Underwood, Robert Walker, Ben Grace, Hugh Barr, Neil A. Shepherd, Oliver Old, James Gossage, Andrew Davies, Fuju Chang, Janine Zylstra, Ula Mahadeva, Vicky Goh, Grant Sanders, Richard Berrisford, Catherine Harden, Mike Lewis, Ed Cheong, Bhaskar Kumar, Simon L. Parsons, Irshad Soomro, Philip Kaye, John Saunders, Laurence Lovat, Rehan Haidry, Laszlo Igali, Michael A. Scott, Sharmila Sothi, Sari Suortamo, Suzy Lishman, George B. Hanna, Christopher J. Peters, Krishna Moorthy, Anna M. Grabowska, Richard Turkington, Damian McManus, David Khoo, W E Fickling, Francesca D. Ciccarelli

Publicerad 2019

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17

Identification of Subtypes of Barrett’s Esophagus and Esophageal Adenocarcinoma Based on DNA Methylation Profiles and Integration of Transcriptome and Genome Data av Sriganesh Jammula, Annalise Katz‐Summercorn, Xiaodun Li, Constanza Linossi, Elizabeth Smyth, Sarah Killcoyne, Daniele Biasci, Vinod V. Subash, Sujath Abbas, Adrienn Blasko, Ginny Devonshire, Amber Grantham, Filip Wronowski, Maria O’Donovan, Nicola Grehan, Matthew Eldridge, Simon Tavaré, Rebecca C. Fitzgerald, Rebecca C. Fitzgerald, Ayesha Noorani, Paul A. Edwards, Nicola Grehan, Barbara Nutzinger, Caitriona Hughes, Elwira Fidziukiewicz, Jan Bornschein, Shona MacRae, Jason Crawte, Alex Northrop, Gianmarco Contino, Xiaodun Li, Rachel de la Rue, Maria O’Donovan, Ahmad Miremadi, Shalini Malhotra, Monika Tripathi, Simon Tavaré, Andy G. Lynch, Matthew Eldridge, Maria Secrier, Lawrence Bower, Ginny Devonshire, Juliane Perner, Sriganesh Jammula, Jim Davies, Charles Crichton, Nick Carroll, Peter Safranek, Andrew Hindmarsh, Vijayendran Sujendran, Stephen J. Hayes, Yeng Ang, Shaun R. Preston, Sarah Oakes, Izhar Bagwan, Vicki Save, Richard J.E. Skipworth, Ted R. Hupp, J. Robert O’Neill, Olga Tucker, Andrew D. Beggs, Philippe Tanière, Susana Puig, Tim Underwood, Fergus Noble, Jack Owsley, Hugh Barr, Neil A. Shepherd, Oliver Old, Jesper Lagergren, James Gossage, Andrew Davies, Fuju Chang, Janine Zylstra, Ula Mahadeva, Vicky Goh, Francesca D. Ciccarelli, Grant Sanders, Richard Berrisford, Catherine Harden, M. H. Lewis, Ed Cheong, Bhaskar Kumar, Simon L. Parsons, Irshad Soomro, Philip Kaye, John Saunders, Laurence Lovat, Rehan Haidry, Laszlo Igali, Michael Scott, Sharmila Sothi, Sari Suortamo, Suzy Lishman, George B. Hanna, Krishna Moorthy, Christopher J. Peters, Anna M. Grabowska, Richard Turkington

Publicerad 2020

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Artigo

Sökresultat - Gianmarco Contino

The Evolving Genomic Landscape of Barrett’s Esophagus and Esophageal Adenocarcinoma av Gianmarco Contino, Thomas L. Vaughan, David C. Whiteman, Rebecca C. Fitzgerald

Lysine-specific Demethylase 2B (KDM2B)-let-7-Enhancer of Zester Homolog 2 (EZH2) Pathway Regulates Cell Cycle Progression and Senescence in Primary Cells av Alexandros Tzatsos, Polina Paskaleva, Stephania Lymperi, Gianmarco Contino, Svetlana Stoykova, Zhao Chen, Kwok‐Kin Wong, Nabeel Bardeesy

KDM2B promotes pancreatic cancer via Polycomb-dependent and -independent transcriptional programs av Alexandros Tzatsos, Polina Paskaleva, Francesco Ferrari, Vikram Deshpande, Svetlana Stoykova, Gianmarco Contino, Kwok‐Kin Wong, Fei Lan, Patrick Trojer, Peter J. Park, Nabeel Bardeesy

<i>STAT3</i> Plays a Critical Role in <i>KRAS</i>-Induced Pancreatic Tumorigenesis av Ryan B. Corcoran, Gianmarco Contino, Vikram Deshpande, Alexandros Tzatsos, Claudius Conrad, Cyril H. Benes, David E. Levy, Jeffrey Settleman, Jeffrey A. Engelman, Nabeel Bardeesy

TGF-β and αvβ6 Integrin Act in a Common Pathway to Suppress Pancreatic Cancer Progression av Aram F. Hezel, Vikram Deshpande, Stephanie M. Zimmerman, Gianmarco Contino, Brinda Alagesan, Michael R. O’Dell, Lee B. Rivera, Jay Harper, Scott Lonning, Rolf A. Brekken, Nabeel Bardeesy

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