Resultats de la cerca - Gerald Schwank

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  1. 1
    Advances in therapeutic CRISPR/Cas9 genome editing

    Advances in therapeutic CRISPR/Cas9 genome editing per Nataša Savić, Gerald Schwank

    Publicat 2015
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  2. 2
    Regulation of Organ Growth by Morphogen Gradients

    Regulation of Organ Growth by Morphogen Gradients per Gerald Schwank, Konrad Basler

    Publicat 2009
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  3. 3
    Growth regulation by Dpp: an essential role for Brinker and a non-essential role for graded signaling levels

    Growth regulation by Dpp: an essential role for Brinker and a non-essential role for graded signaling levels per Gerald Schwank, Simon Restrepo, Konrad Basler

    Publicat 2008
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  4. 4
    State‐of‐the‐art 2023 on gene therapy for phenylketonuria

    State‐of‐the‐art 2023 on gene therapy for phenylketonuria per Michael Martinez, Cary O. Harding, Gerald Schwank, Beat Thöny

    Publicat 2023
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  5. 5
    Generation of BAC Transgenic Epithelial Organoids

    Generation of BAC Transgenic Epithelial Organoids per Gerald Schwank, Amanda Andersson-Rolf, Bon‐Kyoung Koo, Nobuo Sasaki, Hans Clevers

    Publicat 2013
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  6. 6
    Antagonistic Growth Regulation by Dpp and Fat Drives Uniform Cell Proliferation

    Antagonistic Growth Regulation by Dpp and Fat Drives Uniform Cell Proliferation per Gerald Schwank, Gerardo Tauriello, Ryohei Yagi, Elizabeth Kranz, Petros Koumoutsakos, Konrad Basler

    Publicat 2011
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  7. 7
    Formation of the Long Range Dpp Morphogen Gradient

    Formation of the Long Range Dpp Morphogen Gradient per Gerald Schwank, Sascha Dalessi, Schu-Fee Yang, Ryohei Yagi, Aitana Morton de Lachapelle, Markus Affolter, Sven Bergmann, Konrad Basler

    Publicat 2011
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  8. 8
    Loss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killing

    Loss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killing per Nina Frey, Luigi Tortola, David Egli, Sharan Janjuha, Tanja Rothgangl, Kim Fabiano Marquart, Franziska Ampenberger, Manfred Köpf, Gerald Schwank

    Publicat 2022
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  9. 9
    Predicting prime editing efficiency and product purity by deep learning

    Predicting prime editing efficiency and product purity by deep learning per Nicolas Mathis, Ahmed Allam, Lucas Kissling, Kim Fabiano Marquart, Lukas Schmidheini, Cristina Solari, Zsolt Balázs, Michael Krauthammer, Gerald Schwank

    Publicat 2023
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  10. 10
    miR-802 Suppresses Acinar-to-Ductal Reprogramming During Early Pancreatitis and Pancreatic Carcinogenesis

    miR-802 Suppresses Acinar-to-Ductal Reprogramming During Early Pancreatitis and Pancreatic Carcinogenesis per Wenjie Ge, Algera Goga, Yuliang He, Pamuditha N. Silva, Christian Hirt, Karolin Herrmanns, Ilaria Guccini, Svenja Godbersen, Gerald Schwank, Markus Stoffel

    Publicat 2021
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  11. 11
    Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility

    Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility per Lukas Schmidheini, Nicolas Mathis, Kim Fabiano Marquart, Tanja Rothgangl, Lucas Kissling, Desirée Böck, Christelle Chanez, Jingrui Priscilla Wang, Martin Jínek, Gerald Schwank

    Publicat 2023
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  12. 12
    Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell–derived IFN-γ

    Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell–derived IFN-γ per Henner F. Farin, Wouter R. Karthaus, Pekka Kujala, Maryam Rakhshandehroo, Gerald Schwank, Robert G.J. Vries, Eric Kalkhoven, Edward E. S. Nieuwenhuis, Hans Clevers

    Publicat 2014
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  13. 13
    Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair

    Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair per Natas̆a Savić, Femke Ringnalda, Helen Lindsay, Christian Berk, Katja Bargsten, Yizhou Li, Dario Neri, Mark D. Robinson, Constance Ciaudo, Jonathan Hall, Martin Jínek, Gerald Schwank

    Publicat 2018
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  14. 14
    Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies

    Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies per Sandro Nuciforo, Isabel Fofana, Matthias S. Matter, Tanja Blumer, Diego Calabrese, Tujana Boldanova, Salvatore Piscuoglio, Stefan Wieland, Femke Ringnalda, Gerald Schwank, Luigi Terracciano, Charlotte K.Y. Ng, Markus H. Heim

    Publicat 2018
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  15. 15
    In vivo prime editing of a metabolic liver disease in mice

    In vivo prime editing of a metabolic liver disease in mice per Desirée Böck, Tanja Rothgangl, Lukas Villiger, Lukas Schmidheini, Mai Matsushita, Nicolas Mathis, Eleonora Ioannidi, Nicole Rimann, Hiu Man Grisch‐Chan, Susanne Kreutzer, Zacharias Kontarakis, Manfred Köpf, Beat Thöny, Gerald Schwank

    Publicat 2022
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  16. 16
    Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance

    Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance per Till Ringel, Nina Frey, Femke Ringnalda, Sharan Janjuha, Sarah Cherkaoui, Stefan Butz, Sumana Srivatsa, Martin Pirkl, Giancarlo Russo, Lukas Villiger, Gerhard Rogler, Hans Clevers, Niko Beerenwinkel, Nicola Zamboni, Tuncay Baubec, Gerald Schwank

    Publicat 2020
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  17. 17
    Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients

    Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients per Gerald Schwank, Bon‐Kyoung Koo, Valentina Sasselli, Johanna F. Dekkers, Inha Heo, Turan Demircan, Nobuo Sasaki, Sander Boymans, Edwin Cuppen, Cornelis K. van der Ent, Edward E. S. Nieuwenhuis, Jeffrey M. Beekman, Hans Clevers

    Publicat 2013
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  18. 18
    Enhancing prime editor activity by directed protein evolution in yeast

    Enhancing prime editor activity by directed protein evolution in yeast per Yanik Weber, Desirée Böck, A. Ivascu, Nicolas Mathis, Tanja Rothgangl, Eleonora Ioannidi, Alex C. Blaudt, Lisa Tidecks, Máté Vadovics, Hiromi Muramatsu, Andreas M. Reichmuth, Kim Fabiano Marquart, Lucas Kissling, Norbert Pardi, Martin Jínek, Gerald Schwank

    Publicat 2024
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  19. 19
    In vivo cytidine base editing of hepatocytes without detectable off-target mutations in RNA and DNA

    In vivo cytidine base editing of hepatocytes without detectable off-target mutations in RNA and DNA per Lukas Villiger, Tanja Rothgangl, Dominik Witzigmann, Rurika Oka, Paulo J.C. Lin, Weihong Qi, Sharan Janjuha, Christian Berk, Femke Ringnalda, Mitchell Beattie, Markus Stoffel, Beat Thöny, Jonathan Hall, Hubert Rehrauer, Ruben van Boxtel, Ying K. Tam, Gerald Schwank

    Publicat 2021
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  20. 20
    Drug screening and genome editing in human pancreatic cancer organoids identifies drug-gene interactions and candidates for off-label therapy

    Drug screening and genome editing in human pancreatic cancer organoids identifies drug-gene interactions and candidates for off-label therapy per Christian Hirt, Tijmen H. Booij, Linda Grob, Patrik Simmler, Nora C. Toussaint, David Keller, Doreen Taube, Vanessa Ludwig, Alexander Goryachkin, Chantal Pauli, Daniela Lenggenhager, Daniel J. Stekhoven, Christian U. Stirnimann, Katharina Endhardt, Femke Ringnalda, Lukas Villiger, Alexander Siebenhüner, Sofia Karkampouna, Marta De Menna, Janette Beshay, Hagen Klett, Marianna Kruithof‐de Julio, Julia Schüler, Gerald Schwank

    Publicat 2022
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