Search Results - Georg Meisl

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  1. 1
    Quantitative analysis of intrinsic and extrinsic factors in the aggregation mechanism of Alzheimer-associated Aβ-peptide

    Quantitative analysis of intrinsic and extrinsic factors in the aggregation mechanism of Alzheimer-associated Aβ-peptide by Georg Meisl, Xiaoting Yang, Birgitta Frohm, Tuomas P. J. Knowles, Sara Linse

    Published 2016
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  2. 2
    Modulation of electrostatic interactions to reveal a reaction network unifying the aggregation behaviour of the Aβ42 peptide and its variants

    Modulation of electrostatic interactions to reveal a reaction network unifying the aggregation behaviour of the Aβ42 peptide and its variants by Georg Meisl, Xiaoting Yang, Christopher M. Dobson, Sara Linse, Tuomas P. J. Knowles

    Published 2017
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  3. 3
    On the role of sidechain size and charge in the aggregation of A <i>β</i> 42 with familial mutations

    On the role of sidechain size and charge in the aggregation of A <i>β</i> 42 with familial mutations by Xiaoting Yang, Georg Meisl, Birgitta Frohm, Eva Thulin, Tuomas P. J. Knowles, Sara Linse

    Published 2018
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  4. 4
    The role of fibril structure and surface hydrophobicity in secondary nucleation of amyloid fibrils

    The role of fibril structure and surface hydrophobicity in secondary nucleation of amyloid fibrils by Dev Thacker, Kalyani Sanagavarapu, Birgitta Frohm, Georg Meisl, Tuomas P. J. Knowles, Sara Linse

    Published 2020
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  5. 5
    Super-resolution imaging reveals α-synuclein seeded aggregation in SH-SY5Y cells

    Super-resolution imaging reveals α-synuclein seeded aggregation in SH-SY5Y cells by Jason C. Sang, Eric Hidari, Georg Meisl, Rohan T. Ranasinghe, Maria Grazia Spillantini, David Klenerman

    Published 2021
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  6. 6
    Oligomer Diversity during the Aggregation of the Repeat Region of Tau

    Oligomer Diversity during the Aggregation of the Repeat Region of Tau by Magnus Kjærgaard, Alexander J. Dear, Franziska Kundel, Seema Qamar, Georg Meisl, Tuomas P. J. Knowles, David Klenerman

    Published 2018
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  7. 7
    Kinetic barriers to α-synuclein protofilament formation and conversion into mature fibrils

    Kinetic barriers to α-synuclein protofilament formation and conversion into mature fibrils by James W. Brown, Georg Meisl, Tuomas P. J. Knowles, Alexander K. Buell, Christopher M. Dobson, Céline Galvagnion

    Published 2018
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  8. 8
    The catalytic nature of protein aggregation

    The catalytic nature of protein aggregation by Alexander J. Dear, Georg Meisl, Thomas C. T. Michaels, Manuela R. Zimmermann, Sara Linse, Tuomas P. J. Knowles

    Published 2020
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  9. 9
    The Aβ40 and Aβ42 peptides self-assemble into separate homomolecular fibrils in binary mixtures but cross-react during primary nucleation

    The Aβ40 and Aβ42 peptides self-assemble into separate homomolecular fibrils in binary mixtures but cross-react during primary nucleation by Risto Cukalevski, Xiaoting Yang, Georg Meisl, Ulrich Weininger, Katja Bernfur, Birgitta Frohm, Tuomas P. J. Knowles, Sara Linse

    Published 2015
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  10. 10
    Mutations associated with familial Parkinson’s disease alter the initiation and amplification steps of α-synuclein aggregation

    Mutations associated with familial Parkinson’s disease alter the initiation and amplification steps of α-synuclein aggregation by Patrick Flagmeier, Georg Meisl, Michele Vendruscolo, Tuomas P. J. Knowles, Christopher M. Dobson, Alexander K. Buell, Céline Galvagnion

    Published 2016
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  11. 11
    Identification of on- and off-pathway oligomers in amyloid fibril formation

    Identification of on- and off-pathway oligomers in amyloid fibril formation by Alexander J. Dear, Georg Meisl, Anđela Šarić, Thomas C. T. Michaels, Magnus Kjærgaard, Sara Linse, Tuomas P. J. Knowles

    Published 2020
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  12. 12
    Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation

    Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation by Céline Galvagnion, Alexander K. Buell, Georg Meisl, Thomas C. T. Michaels, Michele Vendruscolo, Tuomas P. J. Knowles, Christopher M. Dobson

    Published 2015
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  13. 13
    Chemical Kinetics for Bridging Molecular Mechanisms and Macroscopic Measurements of Amyloid Fibril Formation

    Chemical Kinetics for Bridging Molecular Mechanisms and Macroscopic Measurements of Amyloid Fibril Formation by Thomas C. T. Michaels, Anđela Šarić, Johnny Habchi, Sean Chia, Georg Meisl, Michele Vendruscolo, Christopher M. Dobson, Tuomas P. J. Knowles

    Published 2018
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  14. 14
    Ultrastructural evidence for self-replication of Alzheimer-associated Aβ42 amyloid along the sides of fibrils

    Ultrastructural evidence for self-replication of Alzheimer-associated Aβ42 amyloid along the sides of fibrils by Mattias Törnquist, Risto Cukalevski, Ulrich Weininger, Georg Meisl, Tuomas P. J. Knowles, Thom Leiding, Anders Malmendal, Mikael Akke, Sara Linse

    Published 2020
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  15. 15
    Mechanism of Secondary Nucleation at the Single Fibril Level from Direct Observations of Aβ42 Aggregation

    Mechanism of Secondary Nucleation at the Single Fibril Level from Direct Observations of Aβ42 Aggregation by Manuela R. Zimmermann, Subhas Chandra Bera, Georg Meisl, Sourav Dasadhikari, Shamasree Ghosh, Sara Linse, Kanchan Garai, Tuomas P. J. Knowles

    Published 2021
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  16. 16
    Physical determinants of the self-replication of protein fibrils

    Physical determinants of the self-replication of protein fibrils by Anđela Šarić, Alexander K. Buell, Georg Meisl, Thomas C. T. Michaels, Christopher M. Dobson, Sara Linse, Tuomas P. J. Knowles, Daan Frenkel

    Published 2016
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  17. 17
    Secondary nucleation of monomers on fibril surface dominates<i>α</i>-synuclein aggregation and provides autocatalytic amyloid amplification

    Secondary nucleation of monomers on fibril surface dominates<i>α</i>-synuclein aggregation and provides autocatalytic amyloid amplification by Ricardo Gaspar, Georg Meisl, Alexander K. Buell, Laurence J. Young, Clemens F. Kaminski, Tuomas P. J. Knowles, Emma Sparr, Sara Linse

    Published 2017
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  18. 18
    Secondary nucleation in amyloid formation

    Secondary nucleation in amyloid formation by Mattias Törnquist, Thomas C. T. Michaels, Kalyani Sanagavarapu, Xiaoting Yang, Georg Meisl, Samuel I. A. Cohen, Tuomas P. J. Knowles, Sara Linse

    Published 2018
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  19. 19
    The Influence of Pathogenic Mutations in α-Synuclein on Biophysical and Structural Characteristics of Amyloid Fibrils

    The Influence of Pathogenic Mutations in α-Synuclein on Biophysical and Structural Characteristics of Amyloid Fibrils by Francesco Simone Ruggeri, Patrick Flagmeier, Janet R. Kumita, Georg Meisl, Dimitri Y. Chirgadze, Marie N. Bongiovanni, Tuomas P. J. Knowles, Christopher M. Dobson

    Published 2020
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  20. 20
    Kinetic diversity of amyloid oligomers

    Kinetic diversity of amyloid oligomers by Alexander J. Dear, Thomas C. T. Michaels, Georg Meisl, David Klenerman, Si Wu, Sarah Perrett, Sara Linse, Christopher M. Dobson, Tuomas P. J. Knowles

    Published 2020
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