Search Results - Geoffrey I. Shapiro

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  1. 1
    Heat Shock Protein 90 Inhibition in Lung Cancer

    Heat Shock Protein 90 Inhibition in Lung Cancer by Takeshi Shimamura, Geoffrey I. Shapiro

    Published 2008
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  2. 2
    Cyclin-dependent kinases (cdks) and the DNA damage response: rationale for cdk inhibitor–chemotherapy combinations as an anticancer strategy for solid tumors

    Cyclin-dependent kinases (cdks) and the DNA damage response: rationale for cdk inhibitor–chemotherapy combinations as an anticancer strategy for solid tumors by Neil Johnson, Geoffrey I. Shapiro

    Published 2010
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  3. 3
    Influenza virus RNA replication in vitro: synthesis of viral template RNAs and virion RNAs in the absence of an added primer

    Influenza virus RNA replication in vitro: synthesis of viral template RNAs and virion RNAs in the absence of an added primer by Geoffrey I. Shapiro, Robert M. Krug

    Published 1988
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  4. 4
    Anticancer drug targets: cell cycle and checkpoint control

    Anticancer drug targets: cell cycle and checkpoint control by Geoffrey I. Shapiro, J. Wade Harper

    Published 1999
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  5. 5
    Development of Phosphoinositide-3 Kinase Pathway Inhibitors for Advanced Cancer

    Development of Phosphoinositide-3 Kinase Pathway Inhibitors for Advanced Cancer by James M. Cleary, Geoffrey I. Shapiro

    Published 2010
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  6. 6
    Influenza virus gene expression: control mechanisms at early and late times of infection and nuclear-cytoplasmic transport of virus-specific RNAs

    Influenza virus gene expression: control mechanisms at early and late times of infection and nuclear-cytoplasmic transport of virus-specific RNAs by Geoffrey I. Shapiro, Theodore Gurney, Robert M. Krug

    Published 1987
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  7. 7
    Targeting CDK4 and CDK6: From Discovery to Therapy

    Targeting CDK4 and CDK6: From Discovery to Therapy by Charles J. Sherr, David Beach, Geoffrey I. Shapiro

    Published 2015
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  8. 8
    Clinical Development of the CDK4/6 Inhibitors Ribociclib and Abemaciclib in Breast Cancer

    Clinical Development of the CDK4/6 Inhibitors Ribociclib and Abemaciclib in Breast Cancer by Romualdo Barroso‐Sousa, Geoffrey I. Shapiro, Sara M. Tolaney

    Published 2016
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  9. 9
    Personalized chemotherapy in triple-negative breast cancer: are we ready for prime time?

    Personalized chemotherapy in triple-negative breast cancer: are we ready for prime time? by Romualdo Barroso‐Sousa, Geoffrey I. Shapiro, Sara M. Tolaney

    Published 2019
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  10. 10
    Combined Depletion of Cell Cycle and Transcriptional Cyclin-Dependent Kinase Activities Induces Apoptosis in Cancer Cells

    Combined Depletion of Cell Cycle and Transcriptional Cyclin-Dependent Kinase Activities Induces Apoptosis in Cancer Cells by Dongpo Cai, Vaughan M. Latham, Xinxin Zhang, Geoffrey I. Shapiro

    Published 2006
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  11. 11
    p16<sup><i>INK4A</i></sup> Participates in a G<sub>1</sub> Arrest Checkpoint in Response to DNA Damage

    p16<sup><i>INK4A</i></sup> Participates in a G<sub>1</sub> Arrest Checkpoint in Response to DNA Damage by Geoffrey I. Shapiro, Christian D. Edwards, Mark E. Ewen, Barrett J. Rollins

    Published 1998
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  12. 12
    Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian Cancer

    Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian Cancer by Panagiotis A. Konstantinopoulos, Raphaël Ceccaldi, Geoffrey I. Shapiro, Alan D. D’Andrea

    Published 2015
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  13. 13
    Inhibition of influenza viral mRNA synthesis in cells expressing the interferon-induced Mx gene product

    Inhibition of influenza viral mRNA synthesis in cells expressing the interferon-induced Mx gene product by Robert M. Krug, Michael W. Shaw, B Broni, Geoffrey I. Shapiro, Otto Haller

    Published 1985
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  14. 14
    MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance

    MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance by Liam Cornell, Seth A. Wander, Tanvi H. Visal, Nikhil Wagle, Geoffrey I. Shapiro

    Published 2019
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  15. 15
    Biomarker-Guided Development of DNA Repair Inhibitors

    Biomarker-Guided Development of DNA Repair Inhibitors by James M. Cleary, Andrew J. Aguirre, Geoffrey I. Shapiro, Alan D. D’Andrea

    Published 2020
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  16. 16
    The Aurora Kinase Inhibitor VX-680 Induces Endoreduplication and Apoptosis Preferentially in Cells with Compromised p53-Dependent Postmitotic Checkpoint Function

    The Aurora Kinase Inhibitor VX-680 Induces Endoreduplication and Apoptosis Preferentially in Cells with Compromised p53-Dependent Postmitotic Checkpoint Function by Farid Gizatullin, Yao Yao, Victor Kung, Matthew W. Harding, Massimo Loda, Geoffrey I. Shapiro

    Published 2006
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  17. 17
    Personalized Tumor Response Assessment in the Era of Molecular Medicine: Cancer-Specific and Therapy-Specific Response Criteria to Complement Pitfalls of RECIST

    Personalized Tumor Response Assessment in the Era of Molecular Medicine: Cancer-Specific and Therapy-Specific Response Criteria to Complement Pitfalls of RECIST by Mizuki Nishino, Jyothi P. Jagannathan, Katherine M. Krajewski, Kevin OʼRegan, Hiroto Hatabu, Geoffrey I. Shapiro, Nikhil H. Ramaiya

    Published 2012
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  18. 18
    First-in-Human Phase I Dose Escalation Study of a Second-Generation Non-Ansamycin HSP90 Inhibitor, AT13387, in Patients with Advanced Solid Tumors

    First-in-Human Phase I Dose Escalation Study of a Second-Generation Non-Ansamycin HSP90 Inhibitor, AT13387, in Patients with Advanced Solid Tumors by Geoffrey I. Shapiro, Eunice L. Kwak, Bruce J. Dezube, Murray Yule, John Ayrton, John F. Lyons, Daruka Mahadevan

    Published 2014
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  19. 19
    Pre-clinical evaluation of cyclin-dependent kinase 2 and 1 inhibition in anti-estrogen-sensitive and resistant breast cancer cells

    Pre-clinical evaluation of cyclin-dependent kinase 2 and 1 inhibition in anti-estrogen-sensitive and resistant breast cancer cells by Neil F. Johnson, J. Bentley, L-Z Wang, David R. Newell, Craig Robson, Geoffrey I. Shapiro, Nicola J. Curtin

    Published 2009
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  20. 20
    A phase I open-label study evaluating the cardiovascular safety of sorafenib in patients with advanced cancer

    A phase I open-label study evaluating the cardiovascular safety of sorafenib in patients with advanced cancer by Anthony W. Tolcher, Leonard J. Appleman, Geoffrey I. Shapiro, Alain C. Mita, Frank Cihon, Arthur Mazzu, P. R. Sundaresan

    Published 2010
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