Zoekresultaten - Geoffrey I. Shapiro

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  1. 1
    Heat Shock Protein 90 Inhibition in Lung Cancer

    Heat Shock Protein 90 Inhibition in Lung Cancer door Takeshi Shimamura, Geoffrey I. Shapiro

    Gepubliceerd in 2008
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  2. 2
    Cyclin-dependent kinases (cdks) and the DNA damage response: rationale for cdk inhibitor–chemotherapy combinations as an anticancer strategy for solid tumors

    Cyclin-dependent kinases (cdks) and the DNA damage response: rationale for cdk inhibitor–chemotherapy combinations as an anticancer strategy for solid tumors door Neil Johnson, Geoffrey I. Shapiro

    Gepubliceerd in 2010
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  3. 3
    Influenza virus RNA replication in vitro: synthesis of viral template RNAs and virion RNAs in the absence of an added primer

    Influenza virus RNA replication in vitro: synthesis of viral template RNAs and virion RNAs in the absence of an added primer door Geoffrey I. Shapiro, Robert M. Krug

    Gepubliceerd in 1988
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  4. 4
    Anticancer drug targets: cell cycle and checkpoint control

    Anticancer drug targets: cell cycle and checkpoint control door Geoffrey I. Shapiro, J. Wade Harper

    Gepubliceerd in 1999
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  5. 5
    Development of Phosphoinositide-3 Kinase Pathway Inhibitors for Advanced Cancer

    Development of Phosphoinositide-3 Kinase Pathway Inhibitors for Advanced Cancer door James M. Cleary, Geoffrey I. Shapiro

    Gepubliceerd in 2010
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  6. 6
    Influenza virus gene expression: control mechanisms at early and late times of infection and nuclear-cytoplasmic transport of virus-specific RNAs

    Influenza virus gene expression: control mechanisms at early and late times of infection and nuclear-cytoplasmic transport of virus-specific RNAs door Geoffrey I. Shapiro, Theodore Gurney, Robert M. Krug

    Gepubliceerd in 1987
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  7. 7
    Targeting CDK4 and CDK6: From Discovery to Therapy

    Targeting CDK4 and CDK6: From Discovery to Therapy door Charles J. Sherr, David Beach, Geoffrey I. Shapiro

    Gepubliceerd in 2015
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  8. 8
    Clinical Development of the CDK4/6 Inhibitors Ribociclib and Abemaciclib in Breast Cancer

    Clinical Development of the CDK4/6 Inhibitors Ribociclib and Abemaciclib in Breast Cancer door Romualdo Barroso‐Sousa, Geoffrey I. Shapiro, Sara M. Tolaney

    Gepubliceerd in 2016
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  9. 9
    Personalized chemotherapy in triple-negative breast cancer: are we ready for prime time?

    Personalized chemotherapy in triple-negative breast cancer: are we ready for prime time? door Romualdo Barroso‐Sousa, Geoffrey I. Shapiro, Sara M. Tolaney

    Gepubliceerd in 2019
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  10. 10
    Combined Depletion of Cell Cycle and Transcriptional Cyclin-Dependent Kinase Activities Induces Apoptosis in Cancer Cells

    Combined Depletion of Cell Cycle and Transcriptional Cyclin-Dependent Kinase Activities Induces Apoptosis in Cancer Cells door Dongpo Cai, Vaughan M. Latham, Xinxin Zhang, Geoffrey I. Shapiro

    Gepubliceerd in 2006
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  11. 11
    p16<sup><i>INK4A</i></sup> Participates in a G<sub>1</sub> Arrest Checkpoint in Response to DNA Damage

    p16<sup><i>INK4A</i></sup> Participates in a G<sub>1</sub> Arrest Checkpoint in Response to DNA Damage door Geoffrey I. Shapiro, Christian D. Edwards, Mark E. Ewen, Barrett J. Rollins

    Gepubliceerd in 1998
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  12. 12
    Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian Cancer

    Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian Cancer door Panagiotis A. Konstantinopoulos, Raphaël Ceccaldi, Geoffrey I. Shapiro, Alan D. D’Andrea

    Gepubliceerd in 2015
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  13. 13
    Inhibition of influenza viral mRNA synthesis in cells expressing the interferon-induced Mx gene product

    Inhibition of influenza viral mRNA synthesis in cells expressing the interferon-induced Mx gene product door Robert M. Krug, Michael W. Shaw, B Broni, Geoffrey I. Shapiro, Otto Haller

    Gepubliceerd in 1985
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  14. 14
    MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance

    MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance door Liam Cornell, Seth A. Wander, Tanvi H. Visal, Nikhil Wagle, Geoffrey I. Shapiro

    Gepubliceerd in 2019
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  15. 15
    Biomarker-Guided Development of DNA Repair Inhibitors

    Biomarker-Guided Development of DNA Repair Inhibitors door James M. Cleary, Andrew J. Aguirre, Geoffrey I. Shapiro, Alan D. D’Andrea

    Gepubliceerd in 2020
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  16. 16
    The Aurora Kinase Inhibitor VX-680 Induces Endoreduplication and Apoptosis Preferentially in Cells with Compromised p53-Dependent Postmitotic Checkpoint Function

    The Aurora Kinase Inhibitor VX-680 Induces Endoreduplication and Apoptosis Preferentially in Cells with Compromised p53-Dependent Postmitotic Checkpoint Function door Farid Gizatullin, Yao Yao, Victor Kung, Matthew W. Harding, Massimo Loda, Geoffrey I. Shapiro

    Gepubliceerd in 2006
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  17. 17
    Personalized Tumor Response Assessment in the Era of Molecular Medicine: Cancer-Specific and Therapy-Specific Response Criteria to Complement Pitfalls of RECIST

    Personalized Tumor Response Assessment in the Era of Molecular Medicine: Cancer-Specific and Therapy-Specific Response Criteria to Complement Pitfalls of RECIST door Mizuki Nishino, Jyothi P. Jagannathan, Katherine M. Krajewski, Kevin OʼRegan, Hiroto Hatabu, Geoffrey I. Shapiro, Nikhil H. Ramaiya

    Gepubliceerd in 2012
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  18. 18
    First-in-Human Phase I Dose Escalation Study of a Second-Generation Non-Ansamycin HSP90 Inhibitor, AT13387, in Patients with Advanced Solid Tumors

    First-in-Human Phase I Dose Escalation Study of a Second-Generation Non-Ansamycin HSP90 Inhibitor, AT13387, in Patients with Advanced Solid Tumors door Geoffrey I. Shapiro, Eunice L. Kwak, Bruce J. Dezube, Murray Yule, John Ayrton, John F. Lyons, Daruka Mahadevan

    Gepubliceerd in 2014
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  19. 19
    Pre-clinical evaluation of cyclin-dependent kinase 2 and 1 inhibition in anti-estrogen-sensitive and resistant breast cancer cells

    Pre-clinical evaluation of cyclin-dependent kinase 2 and 1 inhibition in anti-estrogen-sensitive and resistant breast cancer cells door Neil F. Johnson, J. Bentley, L-Z Wang, David R. Newell, Craig Robson, Geoffrey I. Shapiro, Nicola J. Curtin

    Gepubliceerd in 2009
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  20. 20
    A phase I open-label study evaluating the cardiovascular safety of sorafenib in patients with advanced cancer

    A phase I open-label study evaluating the cardiovascular safety of sorafenib in patients with advanced cancer door Anthony W. Tolcher, Leonard J. Appleman, Geoffrey I. Shapiro, Alain C. Mita, Frank Cihon, Arthur Mazzu, P. R. Sundaresan

    Gepubliceerd in 2010
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