Search Results - Gennaro Napolitano

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  1. 1
    TFEB at a glance

    TFEB at a glance by Gennaro Napolitano, Andrea Ballabio

    Published 2016
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  2. 2
    Non-canonical mTORC1 signaling at the lysosome

    Non-canonical mTORC1 signaling at the lysosome by Gennaro Napolitano, Chiara Di Malta, Andrea Ballabio

    Published 2022
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  3. 3
    Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase–activating protein Gem-interacting protein

    Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase–activating protein Gem-interacting protein by Jennifer L. Johnson, Jlenia Monfregola, Gennaro Napolitano, William B. Kiosses, Sergio Catz

    Published 2012
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  4. 4
    Upregulation of the Rab27a-Dependent Trafficking and Secretory Mechanisms Improves Lysosomal Transport, Alleviates Endoplasmic Reticulum Stress, and Reduces Lysosome Overload in Cystinosis

    Upregulation of the Rab27a-Dependent Trafficking and Secretory Mechanisms Improves Lysosomal Transport, Alleviates Endoplasmic Reticulum Stress, and Reduces Lysosome Overload in Cy... by Jennifer L. Johnson, Gennaro Napolitano, Jlenia Monfregola, Céline J. Rocca, Stéphanie Cherqui, Sergio Catz

    Published 2013
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  5. 5
    Impairment of chaperone‐mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis

    Impairment of chaperone‐mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis by Gennaro Napolitano, Jennifer L. Johnson, Jing He, Céline J. Rocca, Jlenia Monfregola, Kersi Pestonjamasp, Stéphanie Cherqui, Sergio Catz

    Published 2015
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  6. 6
    Crystal structure of inhibitor of κB kinase β

    Crystal structure of inhibitor of κB kinase β by Guozhou Xu, Yu-Chih Lo, Qiubai Li, Gennaro Napolitano, Xuefeng Wu, Xuliang Jiang, Michel Dréano, Michael Karin, Hao Wu

    Published 2011
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  7. 7
    A SPLICS reporter reveals $${{{{{\boldsymbol{\alpha }}}}}}$$-synuclein regulation of lysosome-mitochondria contacts which affects TFEB nuclear translocation

    A SPLICS reporter reveals $${{{{{\boldsymbol{\alpha }}}}}}$$-synuclein regulation of lysosome-mitochondria contacts which affects TFEB nuclear translocation by Flavia Giamogante, Lucia Barazzuol, Francesca Maiorca, Elena Poggio, Alessandra Esposito, Anna Masato, Gennaro Napolitano, Alessio Vagnoni, Tito Calì, Marisa Brini

    Published 2024
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  8. 8
    Structure of the lysosomal mTORC1–TFEB–Rag–Ragulator megacomplex

    Structure of the lysosomal mTORC1–TFEB–Rag–Ragulator megacomplex by Zhicheng Cui, Gennaro Napolitano, Mariana E. G. de Araújo, Alessandra Esposito, Jlenia Monfregola, Lukas A. Huber, Andrea Ballabio, James H. Hurley

    Published 2023
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  9. 9
    mTOR-dependent phosphorylation controls TFEB nuclear export

    mTOR-dependent phosphorylation controls TFEB nuclear export by Gennaro Napolitano, Alessandra Esposito, Heejun Choi, Maria Matarese, Valerio Benedetti, Chiara Di Malta, Jlenia Monfregola, Diego L. Medina, Jennifer Lippincott‐Schwartz, Andrea Ballabio

    Published 2018
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  10. 10
    The CLN3 gene and protein: What we know

    The CLN3 gene and protein: What we know by Myriam Mirza, Anna Vainshtein, Alberto DiRonza, Uma Chandrachud, Luke J. Haslett, Michela Palmieri, Stephan Storch, Janos Groh, Niv Dobzinski, Gennaro Napolitano, Carolin Schmidtke, Danielle Kerkovich

    Published 2019
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  11. 11
    TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy

    TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy by Israel C. Nnah, Biao Wang, Chaitali Saqcena, Gregory F. Weber, Edward M. Bonder, Dustin Bagley, Rossella De Cegli, Gennaro Napolitano, Diego L. Medina, Andrea Ballabio, Radek Dobrowolski

    Published 2018
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  12. 12
    Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A

    Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A by Jinzhong Zhang, Jennifer L. Johnson, Jing He, Gennaro Napolitano, Mahalakshmi Ramadass, Céline J. Rocca, William B. Kiosses, Cecilia Bucci, Qisheng Xin, Evripidis Gavathiotis, Ana María Cuervo, Stéphanie Cherqui, Sergio Catz

    Published 2017
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  13. 13
    Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells

    Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells by Laura Rita Rega, Elena Polishchuk, Sandro Montefusco, Gennaro Napolitano, Giulia Tozzi, Jinzhong Zhang, Francesco Bellomo, Anna Taranta, Anna Pastore, Roman Polishchuk, Fiorella Piemonte, Diego L. Medina, Sergio Catz, Andrea Ballabio, Francesco Emma

    Published 2016
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  14. 14
    Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence

    Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence by Hanlin Zhang, Ghada Alsaleh, Jack Feltham, Yizhe Sun, Gennaro Napolitano, Thomas Riffelmacher, Philip D. Charles, Lisa Frau, Philip Hublitz, Zhanru Yu, Shabaz Mohammed, Andrea Ballabio, Stefan Balabanov, Jane Mellor, Anna Katharina Simon

    Published 2019
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  15. 15
    A network-based approach to overcome BCR::ABL1-independent resistance in chronic myeloid leukemia

    A network-based approach to overcome BCR::ABL1-independent resistance in chronic myeloid leukemia by Valeria Bica, Veronica Venafra, Giorgia Massacci, Simone Graziosi, Silvio Gualdi, Gessica Minnella, Federica Sorà, Patrizia Chiusolo, Maria Elsa Brunetti, Gennaro Napolitano, M. Breccia, Dimitrios Mougiakakos, Martin Böttcher, Thomas Fischer, Livia Perfetto, Francesca Sacco

    Published 2025
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  16. 16
    A substrate-specific mTORC1 pathway underlies Birt–Hogg–Dubé syndrome

    A substrate-specific mTORC1 pathway underlies Birt–Hogg–Dubé syndrome by Gennaro Napolitano, Chiara Di Malta, Alessandra Esposito, Mariana E. G. de Araújo, Salvatore Pece, Giovanni Bertalot, Maria Matarese, Valerio Benedetti, Angela Zampelli, Taras Stasyk, Diletta Siciliano, Alessandro Venuta, Marcella Cesana, Claudia Vilardo, Edoardo Nusco, Jlenia Monfregola, Alessia Calcagnì, Pier Paolo Di Fiore, Lukas A. Huber, Andrea Ballabio

    Published 2020
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  17. 17
    Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy

    Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy by Giorgia Di Lorenzo, Francescopaolo Iavarone, Marianna Maddaluno, Ana Belén Plata-Gómez, Simone Aureli, Camila Paz Quezada Meza, Laura Cinque, Alessandro Palma, Alessio Reggio, Carmine Cirillo, Francesca Sacco, Alexandra Stolz, Gennaro Napolitano, Oriano Marin, Lorenzo A. Pinna, Maria Ruzzene, Vittorio Limongelli, Alejo Efeyan, Paolo Grumati, Carmine Settembre

    Published 2022
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  18. 18
    c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder

    c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder by Pablo S. Contreras, Pablo Tapía, Lila González-Hódar, Ivana Peluso, Chiara Soldati, Gennaro Napolitano, Maria Matarese, Macarena Las Heras, Cristian Valls, Alexis Martínez, Elisa Balboa, Juan Francisco Castro, Nancy Leal, Frances M. Platt, Andrzej Sobota, Dominic Winter, Andrés D. Klein, Diego L. Medina, Andrea Ballabio, Alejandra Álvarez, Silvana Zanlungo

    Published 2020
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  19. 19
    TFEB drives mTORC1 hyperactivation and kidney disease in Tuberous Sclerosis Complex

    TFEB drives mTORC1 hyperactivation and kidney disease in Tuberous Sclerosis Complex by Nicola Alesi, Damir Khabibullin, Dean M. Rosenthal, Elie W. Akl, Pieter M. Cory, Michel Alchoueiry, S. Salem, Melissa Daou, William F. Gibbons, Jennifer A. Chen, Long Zhang, Harilaos Filippakis, Laura Graciotti, Caterina Miceli, Jlenia Monfregola, Claudia Vilardo, Manrico Morroni, Chiara Di Malta, Gennaro Napolitano, Andrea Ballabio, Elizabeth P. Henske

    Published 2024
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  20. 20
    Current methods to analyze lysosome morphology, positioning, motility and function

    Current methods to analyze lysosome morphology, positioning, motility and function by Duarte C. Barral, Leopoldo Staiano, Cláudia G. Almeida, Dan F. Cutler, Emily R. Eden, Clare E. Futter, Antony Galione, André R. A. Marques, Diego L. Medina, Gennaro Napolitano, Carmine Settembre, Otília V. Vieira, Johannes M. F. G. Aerts, Peace Atakpa‐Adaji, Giovanni Bruno, Antonella Capuozzo, Elvira De Leonibus, Chiara Di Malta, Cristina Escrevente, Alessandra Esposito, Paolo Grumati, Michael J. Hall, Rita O. Teodoro, Susana S. Lopes, J. Paul Luzio, Jlenia Monfregola, Sandro Montefusco, Frances M. Platt, Roman Polishchuck, Maria De Risi, Irene Sambri, Chiara Soldati, Miguel C. Seabra

    Published 2022
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