Search Results - Gareth Jenkins
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The bile acid deoxycholic acid has a non-linear dose response for DNA damage and possibly NF- B activation in oesophageal cells, with a mechanism of action involving ROS by Gareth Jenkins, J. Cronin, Ali Al-Hamdani, N. Rawat, F. R. D'Souza, Tojo Thomas, Zakaria Eltahir, A P Griffiths, J N Baxter
Published 2008Artigo -
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Inducible Nitric Oxide Synthase (iNOS) and Nitric Oxide (NO) are Important Mediators of Reflux-induced Cell Signalling in Esophageal Cells by Elizabeth McAdam, Hasan Haboubi, Gene D. Forrester, Zakaria Eltahir, Samantha Spencer-Harty, C. A. Davies, A P Griffiths, J N Baxter, Gareth Jenkins
Published 2012Artigo -
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Adaptation of the <i>in vitro</i> micronucleus assay for genotoxicity testing using 3D liver models supporting longer-term exposure durations by Gillian E. Conway, Ume-Kulsoom Shah, Samantha V. Llewellyn, Tereza Červená, Stephen J. Evans, Abdullah Ali, Gareth Jenkins, Martin J. D. Clift, Shareen H. Doak
Published 2020Artigo -
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New approaches to advance the use of genetic toxicology analyses for human health risk assessment by George E. Johnson, Wout Slob, Shareen H. Doak, Mick D. Fellows, B. Bhaskar Gollapudi, Robert H. Heflich, Ben J. Rees, Lya G. Soeteman‐Hernández, Jatin R. Verma, John W. Wills, Gareth Jenkins, Paul A. White
Published 2014Artigo
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Biology
Chemistry
Genetics
Medicine
Molecular biology
Biochemistry
DNA
DNA damage
Gene
Toxicology
Bile acid
Cancer
Cancer research
Carcinogen
DNA repair
Genotoxicity
In vitro
Micronucleus
Micronucleus test
Organic chemistry
Toxicity
Adenocarcinoma
Andrology
Carcinogenesis
Deoxycholic acid
Ethylnitrosourea
Hypoxanthine-guanine phosphoribosyltransferase
Internal medicine
Methyl methanesulfonate
Mutant