Resultats de la cerca - Gareth Howell

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  1. 1
    The VEGFR2 receptor tyrosine kinase undergoes constitutive endosome-to-plasma membrane recycling

    The VEGFR2 receptor tyrosine kinase undergoes constitutive endosome-to-plasma membrane recycling per Helen M. Jopling, Gareth Howell, Nikita Gamper, Sreenivasan Ponnambalam

    Publicat 2011
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  2. 2
    Fas-Fas Ligand Interactions Are Essential for the Binding to and Killing of Activated Macrophages by γδ T Cells

    Fas-Fas Ligand Interactions Are Essential for the Binding to and Killing of Activated Macrophages by γδ T Cells per Jane E. Dalton, Gareth Howell, Jayne Pearson, Phillip Scott, Simon R. Carding

    Publicat 2004
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  3. 3
    Extracellular and Luminal pH Regulation by Vacuolar H+-ATPase Isoform Expression and Targeting to the Plasma Membrane and Endosomes

    Extracellular and Luminal pH Regulation by Vacuolar H+-ATPase Isoform Expression and Targeting to the Plasma Membrane and Endosomes per Gina A. Smith, Gareth Howell, Clair Phillips, Stephen P. Muench, Sreenivasan Ponnambalam, Michael A. Harrison

    Publicat 2016
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  4. 4
    Effects of Foot-and-Mouth Disease Virus Nonstructural Proteins on the Structure and Function of the Early Secretory Pathway: 2BC but Not 3A Blocks Endoplasmic Reticulum-to-Golgi Transport

    Effects of Foot-and-Mouth Disease Virus Nonstructural Proteins on the Structure and Function of the Early Secretory Pathway: 2BC but Not 3A Blocks Endoplasmic Reticulum-to-Golgi Tr... per Katy Moffat, Gareth Howell, Caroline Knox, Graham J. Belsham, Paul Monaghan, Martin D. Ryan, Thomas Wileman

    Publicat 2005
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  5. 5
    Effect of parasitic infection on dopamine biosynthesis in dopaminergic cells

    Effect of parasitic infection on dopamine biosynthesis in dopaminergic cells per Heather L. Martin, Isra Alsaady, Gareth Howell, Emese Prandovszky, Chris Peers, Philip Robinson, Glenn A. McConkey

    Publicat 2015
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  6. 6
    Trafficking of the Menkes copper transporter ATP7A is regulated by clathrin-, AP-2–, AP-1–, and Rab22-dependent steps

    Trafficking of the Menkes copper transporter ATP7A is regulated by clathrin-, AP-2–, AP-1–, and Rab22-dependent steps per Zoe G. Holloway, Antonio Velayos‐Baeza, Gareth Howell, Clotilde Lévecque, Sreenivasan Ponnambalam, Elizabeth Sztul, Anthony P. Monaco

    Publicat 2013
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  7. 7
    Inhibition of the Secretory Pathway by Foot-and-Mouth Disease Virus 2BC Protein Is Reproduced by Coexpression of 2B with 2C, and the Site of Inhibition Is Determined by the Subcellular Location of 2C

    Inhibition of the Secretory Pathway by Foot-and-Mouth Disease Virus 2BC Protein Is Reproduced by Coexpression of 2B with 2C, and the Site of Inhibition Is Determined by the Subcell... per Katy Moffat, Caroline Knox, Gareth Howell, Sarah J. Clark, Huan Yang, Graham J. Belsham, Martin D. Ryan, Thomas Wileman

    Publicat 2006
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  8. 8
    Intrinsic Tyrosine Kinase Activity is Required for Vascular Endothelial Growth Factor Receptor 2 Ubiquitination, Sorting and Degradation in Endothelial Cells

    Intrinsic Tyrosine Kinase Activity is Required for Vascular Endothelial Growth Factor Receptor 2 Ubiquitination, Sorting and Degradation in Endothelial Cells per Lorna C. Ewan, Helen M. Jopling, Haiyan Jia, Shweta Mittar, Azadeh Bagherzadeh, Gareth Howell, John H. Walker, Ian Zachary, Sreenivasan Ponnambalam

    Publicat 2006
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  9. 9
    TRPM2-mediated intracellular Zn2+ release triggers pancreatic β-cell death

    TRPM2-mediated intracellular Zn2+ release triggers pancreatic β-cell death per Paul T. Manna, Tim S. Munsey, Nada Abuarab, Fangfang Li, Aruna Asipu, Gareth Howell, Alicia Sedo, Wei Yang, Jacqui Naylor, David J. Beech, Lin‐Hua Jiang, Asipu Sivaprasadarao

    Publicat 2015
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  10. 10
    A Heat-Shock Protein Axis Regulates VEGFR2 Proteolysis, Blood Vessel Development and Repair

    A Heat-Shock Protein Axis Regulates VEGFR2 Proteolysis, Blood Vessel Development and Repair per Alexander Bruns, Nadira Yuldasheva, Antony M. Latham, Leyuan Bao, Caroline Pellet‐Many, Paul Frankel, Sam L. Stephen, Gareth Howell, Stephen B. Wheatcroft, Mark T. Kearney, Ian Zachary, Sreenivasan Ponnambalam

    Publicat 2012
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  11. 11
    Merkel Cell Polyomavirus Small T Antigen Mediates Microtubule Destabilization To Promote Cell Motility and Migration

    Merkel Cell Polyomavirus Small T Antigen Mediates Microtubule Destabilization To Promote Cell Motility and Migration per Laura M. Knight, Gabrielė Stakaitytė, J. Wood Jennifer, Hussein Abdul-Sada, David Griffiths, Gareth Howell, Rachel Wheat, G. Eric Blair, Neil Steven, Andrew Macdonald, David J. Blackbourn, Adrian Whitehouse

    Publicat 2014
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  12. 12
    High-Risk Human Papillomavirus E5 Oncoprotein Displays Channel-Forming Activity Sensitive to Small-Molecule Inhibitors

    High-Risk Human Papillomavirus E5 Oncoprotein Displays Channel-Forming Activity Sensitive to Small-Molecule Inhibitors per Laura F. Wetherill, Kristopher K. Holmes, Mark Verow, Marietta Müller, Gareth Howell, Mark Harris, Colin W. G. Fishwick, Nicola J. Stonehouse, Richard Foster, G. Eric Blair, Stephen Griffin, Andrew Macdonald

    Publicat 2012
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  13. 13
    Proteolytic shedding of the prion protein via activation of metallopeptidase ADAM10 reduces cellular binding and toxicity of amyloid-β oligomers

    Proteolytic shedding of the prion protein via activation of metallopeptidase ADAM10 reduces cellular binding and toxicity of amyloid-β oligomers per Heledd Jarosz-Griffiths, Nicola J. Corbett, Helen Rowland, Kate Fisher, Alys Jones, Jennifer Baron, Gareth Howell, Sally A. Cowley, Satyan Chintawar, M. Zameel Cader, Katherine A. B. Kellett, Nigel M. Hooper

    Publicat 2019
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  14. 14
    Hypoxia coordinates the spatial landscape of myeloid cells within glioblastoma to affect survival

    Hypoxia coordinates the spatial landscape of myeloid cells within glioblastoma to affect survival per Michael Haley, Leoma Bere, James Minshull, Sokratia Georgaka, Natalia Garcia-Martin, Gareth Howell, David Coope, Federico Roncaroli, Andrew T. King, David C. Wedge, Stuart M. Allan, Omar Pathmanaban, David Brough, Kevin N. Couper

    Publicat 2024
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  15. 15
    Generation of specific inhibitors of SUMO-1– and SUMO-2/3–mediated protein-protein interactions using Affimer (Adhiron) technology

    Generation of specific inhibitors of SUMO-1– and SUMO-2/3–mediated protein-protein interactions using Affimer (Adhiron) technology per David J. Hughes, Christian Tiede, Natalie Penswick, Anna A. Tang, Chi H. Trinh, Upasana Mandal, Katarzyna Z. Zajac, Thembaninkosi G. Gaule, Gareth Howell, Thomas A. Edwards, Jianxin Duan, Eric Feyfant, Michael J. McPherson, Darren C. Tomlinson, Adrian Whitehouse

    Publicat 2017
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  16. 16
    Mgl2+ cDC2s coordinate fungal allergic airway type 2, but not type 17, inflammation in mice

    Mgl2+ cDC2s coordinate fungal allergic airway type 2, but not type 17, inflammation in mice per Peter C. Cook, Sheila Brown, Emma L. Houlder, Julio Furlong-Silva, Daniel P. Conn, Stefano A. P. Colombo, Syed Murtuza Baker, Freya R. Svedberg, Gareth Howell, Margherita Bertuzzi, Louis Boon, Joanne E. Konkel, Christopher R. Thornton, Judith E. Allen, Andrew S. MacDonald

    Publicat 2025
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  17. 17
    The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation

    The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation per Freya R. Svedberg, Sheila Brown, Maria Z. Krauss, Laura Campbell, Catherine Sharpe, Maryam Clausen, Gareth Howell, Howard Clark, Jens Madsen, Christopher M. Evans, Tara E. Sutherland, Alasdair Ivens, David J. Thornton, Richard K. Grencis, Tracy Hussell, Danen Cunoosamy, Peter C. Cook, Andrew S. MacDonald

    Publicat 2019
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